• Other names in common use include acyl-ACP dehydrogenase, reductase, enoyl-[acyl carrier protein] (reduced nicotinamide, adenine dinucleotide phosphate), NADPH 2-enoyl Co A reductase, enoyl acyl-carrier-protein reductase, enoyl-ACP reductase, and enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific). (wikipedia.org)
  • Short-chain acyl-coenzyme A dehydrogenase deficiency. (harvard.edu)
  • Coordinated and reversible reduction of enzymes involved in terminal oxidative metabolism in skeletal muscle mitochondria from a riboflavin-responsive, multiple acyl-CoA dehydrogenase deficiency patient. (harvard.edu)
  • Anesthetic considerations for a patient with compound heterozygous medium-chain Acyl-CoA dehydrogenase deficiency. (harvard.edu)
  • Neonatal screening for medium--chain acyl-CoA dehydrogenase deficiency. (harvard.edu)
  • Compound heterozygosity in four asymptomatic siblings with medium-chain acyl-CoA dehydrogenase deficiency. (harvard.edu)
  • Short-chain acyl-CoA dehydrogenase deficiency: a cause of ophthalmoplegia and multicore myopathy. (harvard.edu)
  • It is a member of the short-chain dehydrogenase/reductase superfamily. (enzyme-database.org)
  • The enzyme is a member of the succinate dehydrogenase/fumarate-reductase family of enzymes [5]. (enzyme-database.org)
  • 7a-hydroxycholesterol then becomes 7a-hydroxy-cholestene-3-one, which is made possible by the enzyme 3-beta-hydroxysteroid dehydrogenase type 7. (smpdb.ca)
  • The systematic name of this enzyme class is acyl-[acyl-carrier-protein]:NADP+ oxidoreductase (B-specific). (wikipedia.org)
  • 1. Fischer, D., Ebenau-Jehle, C. and Grisebach, H. Phytoalexin synthesis in soybean: purification and characterization of NADPH:2'-hydroxydaidzein oxidoreductase from elicitor-challenged soybean cell cultures. (qmul.ac.uk)
  • The enzyme has a preference for NADPH as the reductant, with NADH being a poor substitute [2]. (enzyme-database.org)
  • This enzyme belongs to the family of oxidoreductases, to be specific, those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. (wikipedia.org)
  • D8 - Enzymes , Coenzymes , and Enzyme Inhibitors. (lookformedical.com)
  • [6] This difference in the ultraviolet absorption spectra between the oxidized and reduced forms of the coenzymes at higher wavelengths makes it simple to measure the conversion of one to another in enzyme assays - by measuring the amount of UV absorption at 340 nm using a spectrophotometer . (wikidoc.org)
  • protein_coding" "AAC74155","flgM","Escherichia coli","anti-sigma factor for FliA (sigma 28) [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74156","flgA","Escherichia coli","assembly protein for flagellar basal-body periplasmic P ring [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74157","flgB","Escherichia coli","flagellar component of cell-proximal portion of basal-body rod [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74158","flgC","Escherichia coli","flagellar component of cell-proximal portion of basal-body rod [Ensembl]. (ntu.edu.sg)
  • protein_coding" "AAC74163","flgH","Escherichia coli","flagellar protein of basal-body outer-membrane L ring [Ensembl]. (ntu.edu.sg)
  • Nasu, S., Wicks, F.D. and Gholson, R.K. L -Aspartate oxidase, a newly discovered enzyme of Escherichia coli , is the B protein of quinolinate synthetase. (enzyme-database.org)
  • The entries below are proposed additions and amendments to the Enzyme Nomenclature list . (enzyme-database.org)
  • Specficially, activation is associated with reduction of the mycobacterial ferric KatG catalase-peroxidase by hydrazine and reaction with oxygen to form an oxyferrous enzyme complex. (illumina.com)
  • In the mitochondria of the cell, sterol 26-hydroxylase converts 3a,7a-dihydroxy-5b-cholestane to 3a,7a,26-trihydroxy-5b-cholestane, which is then converted to 3a,7a-dihydroxy-5b-cholestan-26-al by the same enzyme used in the previous reaction. (smpdb.ca)
  • This enzyme participates in fatty acid biosynthesis. (wikipedia.org)
  • An enzyme that catalyzes the oxidation of acyl-[acyl-carrier protein] to trans-2,3-dehydroacyl-[acyl-carrier protein] in the fatty acid biosynthesis pathway. (umassmed.edu)
  • Therefore, the relevance of S. pasteuri exoproteome in the buffalo cervical mucus during the estrus phase was analyzed using LC-MS/MS. As many as 219 proteins were identified, among which elongation factor Tu (EF-Tu), 60-kDa chaperonin (Cpn60), enolase, fructose-bisphosphate aldolase class 1 (FBP aldolase), enoyl-[acyl-carrier-protein] reductase [NADPH] (ENR) and lipoprotein (Lpp) were the functionally important candidates. (bvsalud.org)
  • Then, bile acyl-CoA synthetase teams up with 3a,7a-dihydroxycoprostanic acid to create 3a,7a-dihydroxy-5b-cholestanoyl-CoA. (smpdb.ca)
  • An enzyme that catalyzes the conversion of prephenate to p-hydroxyphenylpyruvate in the presence of NAD . (nih.gov)
  • It catalyzes the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. (nih.gov)
  • This enzyme catalyzes the final step in methanogenesis, the biological production of methane . (lookformedical.com)
  • Upon decomposition, they form products that are enzyme inhibitors . (wikidoc.org)
  • Peroxisomal acyl coenzyme A oxidase 2 converts 3a,7a-dihydroxy-5b-cholestanoyl-CoA into 3a,7a-dihydoxy-5b-cholest-24-enoyl-CoA. (smpdb.ca)
  • D-Amino acid oxidase (DAAO) is one of the main enzymes that metabolize D-Amino acids via deamination. (smpdb.ca)
  • The enzyme requires the hydroporphinoid nickel complex coenzyme F430. (lookformedical.com)
  • By comparison, we found that various genes associated with acyl editing, fatty acid β-oxidation, triacylglycerol assembly and oil-body formation had greater expression levels at middle developmental stage (38 DAP), which are consistent with the fast accumulation of EFA in V. galamensis developing seed, implying their fundamental roles in EFA production. (researchsquare.com)
  • Enzymes that catalyze the first step in the beta-oxidation of FATTY ACIDS. (harvard.edu)
  • Measurement of tissue acyl-CoAs using flow-injection tandem mass spectrometry: acyl-CoA profiles in short-chain fatty acid oxidation defects. (harvard.edu)
  • Ringer, K.L., McConkey, M.E., Davis, E.M., Rushing, G.W. and Croteau, R. Monoterpene double-bond reductases of the (-)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (-)-isopiperitenone reductase and (+)-pulegone reductase of peppermint. (enzyme-database.org)
  • The ability of the enzyme to use both O 2 and fumarate in cofactor reoxidation enables it to function under both aerobic and anaerobic conditions [5]. (enzyme-database.org)
  • Specifically isoniazid inhibits InhA, the enoyl reductase from Mycobacterium tuberculosis , by forming a covalent adduct with the NAD cofactor. (illumina.com)
  • Skeletal muscle MnSOD, mitochondrial complex II, and SIRT3 enzyme activities are decreased in maternal obesity during human pregnancy and gestational diabetes mellitus. (ouhsc.edu)
  • The enzyme participates in the menthol-biosynthesis pathway of Mentha plants. (enzyme-database.org)
  • So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. (wikidoc.org)
  • Bacterial extracellular proteins participate in the host cell communication by virtue of the modulation of pathogenicity, commensalism and mutualism. (bvsalud.org)
  • Consequently, it is important to determine the significance of the specific abundance of S. pasteuri during the estrus phase of the buffalo host, particularly from the perspective of whether this bacterial species is capable of contributing to sexual communication via its extracellular proteins and volatiles. (bvsalud.org)
  • The present findings suggest that S. pasteuri extracellular proteins may play an important role in buffalo sexual communication during the estrus phase. (bvsalud.org)
  • Water is also central to acid-base neutrality and enzyme function. (hmdb.ca)
  • This enzyme is used another time, to create 3a,7a-dihydroxycoprostanic acid. (smpdb.ca)
  • Although lipids are a distinct class of biomolecules, we shall see that they often occur combined, either covalently or through weak bonds, with members of other classes of bio-molecules to yield hybrid molecules such as glycolipids , which contain both carbohydrate and lipid groups, "and lipoproteins , which contain both lipids and proteins. (medmuv.com)
  • In the enteric bacteria, this enzyme also possesses chorismate mutase activity, thereby catalyzing the first two steps in the biosynthesis of tyrosine. (nih.gov)
  • Sigma-54 interaction domain, Bacterial regulatory protein, Propionate catabolism activator [Interproscan]. (ntu.edu.sg)
  • An enzyme active in prostaglandin E and F catabolism. (nih.gov)
  • protein_coding" "Cz03g27200.t1","No alias","Chromochloris zofingiensis","CRAL-TRIO lipid binding domain [Interproscan]. (ntu.edu.sg)
  • From there, propionyl-CoA and chenodeoxycholoyl-CoA join forces and enlist the help of non-specific lipid transfer protein to further chenodeoxycholoyl-CoAâ€TMs journey in the peroxisome. (smpdb.ca)
  • It has a preference for acyl derivatives with carbon chain length from 4 to 16. (umassmed.edu)
  • These components of the pathway occur in the endoplasmic reticulum membrane, although 2 enzymes, 25-hydroxycholesterol 7-alpha-hydroxylase and sterol 26 hydroxylase, are found in the mitochondria. (smpdb.ca)
  • Reactome analysis revealed innate immune system, neutrophil degranulation, cell surface interactions at the vascular wall, and FCERI-mediated NF-kB activation as the major pathways to which the salivary proteins identified during EPR are associated. (bvsalud.org)
  • LysR substrate binding domain, Bacterial regulatory helix-turn-helix protein [Interproscan]. (ntu.edu.sg)
  • Protein of unknown function (DUF454) [Interproscan]. (ntu.edu.sg)
  • Binding-protein-dependent transport system inner membrane component [Interproscan]. (ntu.edu.sg)
  • FlgN protein [Interproscan]. (ntu.edu.sg)
  • Flagella basal body rod protein [Interproscan]. (ntu.edu.sg)
  • Flagella basal body rod protein, Flagellar basal body rod FlgEFG protein C-terminal [Interproscan]. (ntu.edu.sg)
  • FlgD Ig-like domain, FlgD Tudor-like domain, Flagellar hook capping protein - N-terminal region [Interproscan]. (ntu.edu.sg)
  • Flagellar L-ring protein [Interproscan]. (ntu.edu.sg)
  • Rod binding protein, Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [Interproscan]. (ntu.edu.sg)
  • Aldo/keto reductase family [Interproscan]. (ntu.edu.sg)
  • HAMP domain, Tar ligand binding domain homologue, Methyl-accepting chemotaxis protein (MCP) signalling domain [Interproscan]. (ntu.edu.sg)
  • Enoyl-(Acyl carrier protein) reductase [Interproscan]. (ntu.edu.sg)
  • protein_coding" "Cz02g30180.t1","No alias","Chromochloris zofingiensis","N-(5'phosphoribosyl) anthranilate isomerase (PRAI) [Interproscan]. (ntu.edu.sg)
  • protein_coding" "Cz04g10270.t1","No alias","Chromochloris zofingiensis","Ribosomal protein L1/ribosomal biogenesis protein [Interproscan]. (ntu.edu.sg)
  • Using a combinatorial pathway library approach, we first mined a historical industrial strain collection for superior enzymes that we used to engineer the autotrophic acetogen Clostridium autoethanogenum . (nature.com)
  • This pathway occurs in the liver, beginning with cholesterol being converted to 7a-hydroxycholesterol through the enzyme cholesterol-7-alpha-monooxygenase, after being transported into the liver cell. (smpdb.ca)
  • Human biochemistry that involves enzymes usually performs optimally around a biologically neutral pH of 7.4. (hmdb.ca)
  • putative site-specific recombinase [Ensembl]. (ntu.edu.sg)
  • The enzyme is highly regioselective for the reduction of the endocyclic 1,2-double bond, and is stereoselective, producing only the 1 R -configured product. (enzyme-database.org)
  • trans-Hexadec-2-enoyl-[acp] = 4 reactions were found. (brenda-enzymes.org)
  • In anabolism, water is removed from molecules (through energy requiring enzymatic chemical reactions) in order to grow larger molecules (e.g. starches, triglycerides and proteins for storage of fuels and information). (hmdb.ca)
  • This compound then uses peroxisomal multifunctional enzyme type 2 to create chenodeoxycholoyl-CoA. (smpdb.ca)
  • However, it is also used in other cellular processes, notably as a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications . (wikidoc.org)
  • As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1ULU and 2YW9. (wikipedia.org)
  • In this scenario the latest discoveries suggest the relevance of nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) to connect ROS production and metabolic control. (biomed.news)
  • Co - enzyme Q10 is part of the electron transport system, involved in energy production within the nucleus of all body cells. (lookformedical.com)
  • After that, aldo-keto reductase family 1 member C4 is used to create 3a,7a-dihydroxy-5b-cholestane. (smpdb.ca)
  • An asterisk before 'EC' indicates that this is an amendment to an existing enzyme rather than a new enzyme entry. (enzyme-database.org)
  • View entry in original ENZYME format View entry in raw text format (no links). (lookformedical.com)
  • It is a highly specific agent, ineffective against other microorganisms. (illumina.com)
  • DAAO is highly specific towards D-amino acids and favours free neutral D-amino acids or those with hydrophobic, polar or aromatic groups. (smpdb.ca)
  • Enoyl-(Acyl-Carrier Protein) Reductase (NADPH, B-Specific)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (umassmed.edu)
  • Gel-based protein separation was performed on saliva, followed by identification of proteins using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS). Totally, 326 proteins were identified in the salivary samples, among which 101 were found to be specific for ruptured ectopic pregnancy (EPR). (bvsalud.org)
  • With the help of water, peroxisomal multifunctional enzyme type 2 turns 3a,7a-dihydoxy-5b-cholest-24-enoyl-CoA into 3a,7a,24-trihydoxy-5b-cholestanoyl-CoA. (smpdb.ca)
  • The date on which an enzyme will be made official is appended after the EC number. (enzyme-database.org)