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  • catalyzes
  • This enzyme catalyzes the biodegradation of fatty acid derivatives known as gangliosides. (wikipedia.org)
  • The HADHB protein catalyzes the final step of beta-oxidation, in which 3-ketoacyl CoA is cleaved by the thiol group of another molecule of Coenzyme A. The thiol is inserted between C-2 and C-3, which yields an acetyl CoA molecule and an acyl CoA molecule, which is two carbons shorter. (wikipedia.org)
  • batch
  • The mixed beta- glucanase and xylanase preparation under evaluation is produced by fed-batch, submerged, pure culture fermentation of a strain of Humicola insolens that is non-pathogenic and non-toxigenic. (inchem.org)
  • Dr Len McEwen, inventor of EPD, speculated that the reason for the failure might have been that the beta glucuronidase enzyme preparation was inadvertently heated or frozen during storage in the hospital pharmacy, as it is sensitive to the storage temperature and enzyme from the same manufactured batch had been used to treat a number of patients successfully. (wikipedia.org)
  • reduces
  • The conversion of B-OHB to acetoacetate catalyzed by the enzyme reduces the NAD+ to NADH, generating an electrical change, the magnitude of which can then be used to extrapolate the amount of beta-hydroxybutyrate in the sample. (wikipedia.org)
  • lipids
  • Persons with mucolipidosis may share some of the clinical features associated with the mucopolysaccharidoses (certain facial features, bony structure abnormalities, and damage to the brain), and increased amounts of the enzymes needed to break down the lipids are found in the blood. (wikipedia.org)
  • When beta-hexosaminidase is no longer functioning properly, the lipids accumulate in the nervous tissue of the brain and cause problems. (wikipedia.org)
  • stabilization
  • Evolution of alpha-amylases: architectural features and key residues in the stabilization of the (beta/alpha)(8) scaffold. (ebi.ac.uk)
  • Chains
  • The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an RNA 5'-triphosphatase. (rcsb.org)
  • Subjects with a mucopolysaccharidosis either do not produce enough of one of the eleven enzymes required to break down these sugar chains into simpler molecules, or they produce enzymes that do not work properly. (wikipedia.org)
  • known
  • The evaluated enzyme preparation, known as 'Ultraflo L', is used in the food industry as a processing aid. (inchem.org)
  • preparation
  • The enzyme preparation contains two main activities, beta- glucanase and xylanase, and several secondary activities, including cellulase, hemicellulase, pentosanase and arabinase. (inchem.org)
  • The preparation is used in beer brewing to hydrolyse beta- glucans, pentosans and other gums. (inchem.org)
  • The recommended dosage is 200 g of the enzyme preparation per 1000 kg of total raw materials, but is dependent on the composition of the raw material. (inchem.org)
  • The mixed beta- glucanase/xylanase preparation is also marketed within the European Union as a feed-additive under the name of 'Pentopan/Biofeed Plus. (inchem.org)
  • The mixed enzyme preparation is standardized on the main activity, beta- glucanase. (inchem.org)
  • In addition, the enzyme preparation contains approximately 470 farbe xylanase units (FXU) per g. (inchem.org)
  • intracellular
  • SEPT8 (show SEPT8 ELISA Kits ) modulates beta-amyloidogenic processing of APP (show APP ELISA Kits ) through a mechanism affecting the intracellular sorting and accumulation of BACE1 . (antibodies-online.com)
  • cofactor
  • Blood beta-hydroxybutyrate levels are measured through a test that uses beta-hydroxybutyrate dehydrogenase, with NAD+ as an electron-accepting cofactor. (wikipedia.org)
  • whereas
  • The aspartyl protease β-site APP cleaving enzyme 1 (BACE1) cleaves APP predominantly at a unique site, whereas the c-secretase complex cleaves the resulting carboxy-terminal fragment at several sites, with preference for positions 40 and 42, leading to formation of amyloid β1-40 (Aβ1-40) and Aβ1-42 peptides. (creative-biogene.com)
  • Site
  • Amylases have at least one conserved calcium-binding site, as calcium is essential for the stability of the enzyme. (ebi.ac.uk)
  • liquid
  • Alternatively, lyophilized or liquid, highly potent preparations of these β-lactamase enzymes are also available. (merckmillipore.com)
  • The liquid enzyme concentrate (LEC) is then stabilized, formulated and standardized by the addition of sorbitol, glycerol, and potassium sorbate. (inchem.org)
  • family
  • This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. (wikipedia.org)
  • formation
  • beta- Glucanase hydrolyses the barley beta- glucans under formation of mono- or oligomers. (inchem.org)
  • The chloride-binding functions to activate the enzyme, which acts by a two-step mechanism involving a catalytic nucleophile base (usually an Asp) and a catalytic proton donor (usually a Glu) that are responsible for the formation of the beta-linked glycosyl-enzyme intermediate. (ebi.ac.uk)
  • Branching enzyme catalyses the formation of alpha-1,6 branch points in either glycogen or starch. (ebi.ac.uk)
  • level
  • This elevated beta-hydroxybutyrate level is naturally expected, as beta-hydroxybutyrate is formed from acetoacetate. (wikipedia.org)
  • treatment
  • Enzyme potentiated desensitization, or EPD, is a treatment for allergies developed in the 1960s by Dr. Leonard M. McEwen in the United Kingdom. (wikipedia.org)
  • EPD uses much lower doses of antigens than conventional desensitization treatment paired with the enzyme β-glucuronidase. (wikipedia.org)
  • The treatment uses dilutions of allergen and enzyme to which T-regulatory lymphocytes are believed to respond by favouring desensitization, or down-regulation, rather than sensitization. (wikipedia.org)
  • essential
  • Alpha-amylase is an essential enzyme in alpha-glucan metabolism, acting to catalyse the hydrolysis of alpha-1,4-glucosidic bonds of glycogen, starch and related polysaccharides. (ebi.ac.uk)
  • component
  • Beta is an important component of the Capital Asset Pricing Model , which attempts to use volatility and risk to estimate expected returns . (thefreedictionary.com)