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  • Proteins
  • You can profile your target enzyme against thousands of substrate compounds or proteins, or study various types of protein modifications including phosphorylation , methylation , ubiquitination , SUMOylation , NEDDylation , and nitrosylation . (profacgen.com)
  • SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al. (genecards.org)
  • vitro
  • Detailed in vitro enzyme kinetic analysis indicated that both soluble Aβ40 and Aβ42 enhanced the catalytic efficiency of ChAT by ∼21% and 26% at physiological concentration ranges found in human cerebrospinal fluid (CSF). (frontiersin.org)
  • results
  • These results indicate that resistance exercise may be an efficient way to increase intramuscular VDR and related enzyme expression. (greenmedinfo.com)
  • Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. (genecards.org)
  • drug
  • Enzyme profiling in disease states or under different treatments (drug, growth factors, hormones, etc. (profacgen.com)
  • system
  • Where this takes place in such a way that the effect is reversible on removing the compound, say by dialysis, and where the compound is unchanged chemically by the enzyme system, we refer to such a compound as a modifier. (biochemj.org)
  • complex
  • Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. (genecards.org)
  • main
  • ChAT is the main enzyme involved in the biosynthesis of the key neurotransmitter acetylcholine (ACh) from choline and acetyl-CoA (ACoA). (frontiersin.org)