• Although ferric enterobactin long eluded crystallization, its definitive three-dimensional structure was ultimately obtained using racemic crystallography, in which crystals of a 1:1 mixture of ferric enterobactin and its mirror image (ferric enantioenterobactin) were grown and analyzed by X-ray crystallography. (wikipedia.org)
  • outer membrane porin, receptor for ferric enterobactin. (ntu.edu.sg)
  • Enterobactin (also known as enterochelin) is a high affinity siderophore that acquires iron for microbial systems. (wikipedia.org)
  • Enterobactin is the strongest siderophore known, binding to the ferric ion (Fe3+) with affinity K = 1052 M−1. (wikipedia.org)
  • Iron deficiency in bacterial cells triggers secretion of enterobactin into the extracellular environment, causing formation of a coordination complex "FeEnt" wherein ferric ion is chelated to the conjugate base of enterobactin. (wikipedia.org)
  • Genes similar to the entCEBA genes of enterobactin biosynthesis involved in the production and activation of dihydroxybenzoic acid (DHB) are present in this cluster, as well as a two-module non-ribosomal peptide synthetase (NRPS). (ucsb.edu)
  • The first three-dimensional structure of a metal enterobactin complex was determined as the vanadium(IV) complex. (wikipedia.org)
  • The reduction potential for Fe3+/Fe2+-enterobactin complex is pH dependent and varies from −0.57 V (vs NHE) at pH 6 to −0.79 V at pH 7.4 to −0.99 at pH values higher than 10.4. (wikipedia.org)
  • The resulting RNA scaffolds functionalized with different aptamers are designed and evaluated for in vitro production of enterobactin. (asu.edu)
  • The best RNA scaffold provides a 418% increase in enterobactin production compared with the system in absence of the RNA scaffold. (asu.edu)
  • Using the NRP enterobactin pathway as a model, RNA scaffolds are developed to direct the assembly of the enzymes entE, entB, and entF from E. coli, along with the aryl-carrier protein dhbB from B. subtilis. (asu.edu)
  • So far, our structures have shown how iron transporters specifically recognize Fe 3+ bound to small molecules such as enterobactin (a siderophore synthesized by Escherichia coli) and citrate. (nih.gov)
  • Deletion of fur resulted in copper hypersensitivity that was alleviated by additional deletion of entC, preventing synthesis of enterobactin. (nih.gov)
  • Catecholates can potentially reduce Cu(II) to the prooxidant Cu(I). In this report we provide evidence that CueO protects E. coli cells by oxidizing enterobactin, the catechol iron siderophore of E. coli, in the presence of copper. (nih.gov)
  • iron-enterobactin transporter permease [Ensembl]. (ntu.edu.sg)