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  • NADH
  • The overall reaction for one cycle of beta oxidation is: Cn-acyl CoA + FAD + NAD+ + H 2O + CoA → Cn-2-acyl CoA + FADH 2 + NADH + H+ + acetyl CoA Fatty acid catabolism consists of: Activation and membrane transport of free fatty acids by binding to coenzyme A. Oxidation of the beta carbon to a carbonyl group. (wikipedia.org)
  • The properties of the fluorescence signal changes when NADH binds to proteins, so these changes can be used to measure dissociation constants, which are useful in the study of enzyme kinetics. (wikipedia.org)
  • carnitine shuttle
  • If the fatty acyl-CoA has a long chain, then the carnitine shuttle must be utilized: Acyl-CoA is transferred to the hydroxyl group of carnitine by carnitine palmitoyltransferase I, located on the cytosolic faces of the outer and inner mitochondrial membranes. (wikipedia.org)
  • In order for the acyl-CoA to enter the mitochondrion the carnitine shuttle is used: Acyl-CoA is transferred to the hydroxyl group of carnitine by carnitine palmitoyltransferase I, located on the cytosolic faces of the outer and inner mitochondrial membranes. (wikipedia.org)
  • pyrimidine
  • The organic acids induced several proteins involved in amino acid biosynthesis, purine and pyrimidine biosynthesis, and cofactor biosynthesis in R. eutropha , but the regulations had a great variation. (ijbs.com)
  • acids
  • The responses of the cells to the organic acids, such as regulation of proteins, can reveal the metabolic activities and mechanisms in detoxification and utilization of different organic acids by the microbial cells [ 10 ]. (ijbs.com)
  • The information on proteins involved in different metabolic pathways, particularly the regulation of the enzymes in cells' responses to different organic acids, is invaluable to biosynthesis of PHA biopolymers. (ijbs.com)
  • sequence
  • Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. (uniprot.org)
  • Download DNA or protein sequence, view genomic context and coordinates. (yeastgenome.org)
  • Basic sequence-derived (length, molecular weight, isoelectric point) and experimentally-determined (median abundance, median absolute deviation) protein information. (yeastgenome.org)
  • Patterns of sequence variation reveal signals of recent selection in specific genes that may contribute to human fitness, and also in regions where no function is evident. (wikipedia.org)
  • synthesis
  • Its main function is to catalyze the synthesis of palmitate (C16:0, a long-chain saturated fatty acid ) from acetyl-CoA and malonyl-CoA , in the presence of NADPH . (wikipedia.org)
  • acetate
  • A number of proteins were found to be induced in R. eutropha by using 1D-PAGE and nano-liquid chromatography tandem MS/MS. With the proteins being up-regulated, a dramatic change occurred in the induction of PHA metabolism, including fatty acid biosynthesis for acetate, β-oxidation for propionate and both for levulinic acid. (ijbs.com)
  • Enzymes
  • However, it is also used in other cellular processes, most notably a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. (wikipedia.org)
  • contains
  • Acetyl-CoA is a single polypeptide chain which contains a biotin carboxyl carrier protein, biotin carboxylase, and carboxyl transferase domains [ 2 , 3 ]. (intechopen.com)
  • However, one weakness of the protein-protein interaction data is that it contains no information about the conditions under which the interactions may take place which means it is not a real snapshot of the interactions in vivo, but a union of the interactions activated under various conditions. (biomedcentral.com)
  • reaction
  • The ACC reaction is a two-step reaction in which the biotin molecule, covalently attached by holo-carboxylase synthetase to the ε-amino group of a lysine residue, acts as the carboxyl carrier [ 5 ]. (intechopen.com)
  • gene
  • So CCDS's gene number prediction represents a lower bound on the total number of human protein-coding genes. (wikipedia.org)
  • beta
  • Following each round of elongation the beta keto group is reduced to the fully saturated carbon chain by the sequential action of a ketoreductase (KR), dehydratase (DH), and enoyl reductase (ER). (wikipedia.org)
  • different
  • p>When browsing through different UniProt proteins, you can use the 'basket' to save them, so that you can back to find or analyse them later. (uniprot.org)
  • scientific
  • p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc. (uniprot.org)
  • structure
  • Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure. (supfam.org)
  • data
  • Except protein interaction network supported, the network will be much more biologically insightful if the expression data is incorporated with them. (biomedcentral.com)
  • cell
  • The network provides a systems-level view of how genes and their products interact within the cell and explain the biological actions under specific condition. (biomedcentral.com)
  • genome
  • In the post-genomic era, proteomic studies analyzing the protein complement of a genome in a particular organism at any given time, have gained real significance. (usf.edu)
  • The genome contained genes of respiratory polysulfide/thiosulfate reductase, however, elemental sulfur and thiosulfate were not used as the electron acceptors for anaerobic respiration with acetate or H 2 , probably due to the lack of the gene of the maturation protein. (frontiersin.org)
  • reduction
  • The ability to reduce nitrate is determined by a nitrate reductase of the Nap family, while nitrite reduction to ammonia is presumably catalyzed by an octaheme cytochrome c nitrite reductase εHao. (frontiersin.org)
  • however
  • However, it is also used in other cellular processes, most notably a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. (wikipedia.org)
  • changes
  • This result is largely due to dynamic changes in protein expression profiles which can lead wide alterations in physiology and behavior. (usf.edu)
  • scientific literature
  • p>An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc. (uniprot.org)