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  • murine
  • 1 ) HGF overexpression and enhanced β-cell engraftment were not associated with increases in β-cell proliferation, 2 ) abundant adenovirus expression persisted the full 6 weeks of the experiment, and 3 ) murine HGF was superior to human HGF (hHGF) in this system. (diabetesjournals.org)
  • The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor CXCR4 were found to be critical for murine bone marrow engraftment by human severe combined immunodeficient (SCID) repopulating stem cells. (sciencemag.org)
  • MSCs
  • Engraftment efficiency is enhanced by using intra-arterial delivery instead of intravenous delivery, thus avoiding the "first-pass" accumulation of MSCs in the lung. (hindawi.com)
  • rate
  • Intravenous treatment with silica particles or L-asparaginase did improve the engraftment rate after 7.5 Gy TBI. (osti.gov)
  • secondary
  • These genome-edited HSPCs support multilineage engraftment and generate progeny capable of trafficking to secondary tissues including the gut. (nih.gov)
  • approaches
  • The technology demonstration here is an improvement over past work on heart tissue, but at 10% engraftment there is clearly a way to go yet when it comes to building better approaches. (fightaging.org)
  • host
  • As HLA-matched donors were often unavailable, during the 1980s and 1990s, several investigators explored ways to promote engraftment in HLA-mismatched conditions where host versus graft reactions are stronger (e.g., following haploidentical HCT) and where fully myeloablative conditioning was often not enough to avoid rejection [ 9 , 10 ]. (hindawi.com)
  • total
  • However, p-preDCs alone or p-preDCs from the FC population facilitate HSC engraftment less efficiently than total FCs. (rupress.org)