Metabolic rateRelated to exercisMitochondrialGlucoseLactateRedoxPathwaysAerobicEcologicalPhysiologicalRegulateExpenditureBody temperatureBirdsOxidativeEnergyHallmarkHormonesMetabolitesProfoundRadiationDeterminesFunctionTemperaturesIncreasesLevelLosing weightPatternCancer cellsJournalCommonUniqueActivityNaturalCenterGroupsMuscle
Metabolic rate5
- This set-up enables determination of basal and resting metabolic rate of mice inside the metabolic chambers. (mouseclinic.de)
- Keep reading to discover not only how metabolism works but how to safely and sustainably maintain a high metabolic rate. (bistromd.com)
- This is otherwise called resting metabolic rate (RMR) or basal metabolic rate (BMR). (bistromd.com)
- Thyroid hormones boost animals' basal metabolic rate and represent an important thermoregulatory pathway for mammals that face cold temperatures. (omeka.net)
- Also emerging from the modelling were the thermal neutral zone and basal metabolic rate characteristic of homeothermic endotherms. (allenpress.com)
Related to exercis1
- Topically, studies using the O2k range from comparative physiological investigations addressing evolutionary and environmental aspects of mitochondrial metabolism over the energetics related to exercise physiology, nutrition and life style , to aspects of clinical interest such as the impact of metabolic diseases , cancer , or pharmacological interventions . (bioblast.at)
Mitochondrial4
- Fairly simple to highly complex, comprehensive experimental protocols can be applied to assess either basal mitochondrial characteristics or obtain diagnostic insight into respiratory pathways. (bioblast.at)
- Specifically, mRNA-sequencing analysis revealed several gene signatures, including reduction of mitochondrial oxidative phosphorylation, fatty acid, and glucose metabolism pathways, and antioxidant response pathways after 24-week dnOGA overexpression. (bvsalud.org)
- Age-related gene expression profiles of the short-lived model animals Caenorhabditis elegans and Drosophila melanogaster share a common adult-onset expression program of genes involved in mitochondrial metabolism, DNA repair, catabolism, peptidolysis and cellular transport 3 . (nature.com)
- In the early 1920s, German biochemist and physiologist Otto Warburg conducted groundbreaking research and proposed the famous "Warburg effect": Tumor cells prefer to use glycolysis for glucose metabolism even in oxygen-rich conditions, rather than more efficient mitochondrial oxidative phosphorylation for ATP production [ 3 ]. (biomedcentral.com)
Glucose10
- Uridine utilization strongly correlated with the expression of uridine phosphorylase 1 (UPP1), which we demonstrate liberates uridine-derived ribose to fuel central carbon metabolism and thereby support redox balance, survival and proliferation in glucose-restricted PDA cells. (biomed.news)
- Glucose is the primary energy source in the brain whose metabolism via the glycolysis pathway leads to pyruvate, which enters the Krebs cycle in the mitochondria or is converted into lactate by LDH [ 10 , 11 ]. (hindawi.com)
- We present here a theoretical meta-analysis that tests whether the brain's unique compartmentation of glycogen metabolism in the astrocyte and the requirement for neuronal glucose homeostasis lead to the observed stoichiometries. (marbilab.it)
- We found that blood-brain barrier glucose transport can be limiting during activation and that the energy demand could only be met if glycogenolysis supports neuronal glucose metabolism by replacing the glucose consumed by astrocytes, a mechanism we call Glucose Sparing by Glycogenolysis (GSG). (marbilab.it)
- The aberrant glucose metabolism is associated with dramatically increased bioenergetics, biosynthetic, and redox demands, which is vital to maintain rapid cell proliferation, tumor progression, and resistance to chemotherapy and radiation. (biomedcentral.com)
- When the glucose metabolism of cancer is rewiring, the characters of cancer will also occur corresponding changes to regulate the chemo- and radio-resistance of cancer. (biomedcentral.com)
- Targeting altered metabolic pathways related with the glucose metabolism has become a promising anti-cancer strategy. (biomedcentral.com)
- This review summarizes recent progress in our understanding of glucose metabolism in chemo- and radio-resistance malignancy, and highlights potential molecular targets and their inhibitors for cancer treatment. (biomedcentral.com)
- As the molecular mechanisms underlying chemo- and radio-resistance are still poorly understood, the alteration of glucose metabolism in cancer provides new ideas to explain chemo- and radio-resistance. (biomedcentral.com)
- We first review the basics of microglial metabolism and the effects of common metabolites, such as glucose, lipids, ketone bodies, glutamine, pyruvate and lactate, on microglial inflammatory and phagocytic properties. (biomedcentral.com)
Lactate3
- Thus, lactate is both a central player in unstressed mammalian metabolism and strongly produced in response to acute stress. (biomed.news)
- This result suggests that taurine improves pyruvate, lactate, and glutamate metabolism, thus decreasing IUI-caused cerebral damage and relieving motor behavior impairment. (hindawi.com)
- In preliminary studies in Huntington's illness patients, Cr appears to favorably impression brain energetics and to cut back lactate production (Beal et al. (justdoitsnow.com)
Redox1
- This indicates the intricate control of metabolism and redox balance for survival of cancer cells that can be targeted by therapeutic agents. (degruyter.com)
Pathways1
- IUI alters cerebral metabolism because it causes a deficiency of oxygen and nutrients essential for maturing the neurochemical circuitry in the neonatal phase, particularly the glutamatergic and GABAergic pathways in the cerebral cortex [ 8 , 9 ]. (hindawi.com)
Aerobic4
- Lovvorn JR. Thermal substitution and aerobic efficiency: measuring and predicting effects of heat balance on endotherm diving energetics. (isbweb.org)
- For example, if endurance training (high repetition, low load contractions) is undertaken the muscular system will undergo specific changes that target aerobic metabolism and improved fatigue resistance. (physio-pedia.com)
- For instance, O 2 supplied by basal melting should result in conditions favourable for aerobic methane oxidation. (darkenergybiosphere.org)
- Aerobic respiratory activity associated with heterotrophic and chemoautotrophic metabolism surpassed the estimated supply of oxygen to SLW, implying that microbial activity could deplete the oxygenated waters, resulting in anoxia. (darkenergybiosphere.org)
Ecological1
- This ecological shift was accompanied by profound changes in locomotion, sensory ecology and metabolism. (peerj.com)
Physiological1
- Here, we use a combination of physiological assays and models to assess the energetics of microbial life in SLW. (darkenergybiosphere.org)
Regulate1
- If the liver does not regulate fat metabolism efficiently, weight gain tends to occur around the abdominal area and a protuberant abdomen (pot belly) will develop. (olitan.com)
Expenditure1
- The energetics of expenditure and gain drive skeletal muscle growth when challenged by resistance training. (nfpt.com)
Body temperature2
- We hypothesize that flight, a factor common to all bats but to no other mammals, provides an intensive selective force for coexistence with viral parasites through a daily cycle that elevates metabolism and body temperature analogous to the febrile response in other mammals. (cdc.gov)
- When animals hibernate, they lower their body temperature and metabolism to conserve the energy they need to withstand cold harsh winters. (elifesciences.org)
Birds2
- We will pay particular attention to the importance of energy and nutrient stores with which the birds arrive at the breeding grounds for egg production, energy turnover of breeding birds in relation to species and microclimate, and the fat deposition and basal metabolism of birds preparing for autumn migration. (amap.no)
- We analyzed and compared the scaling of both basal and maximal thermogenic metabolic rates in passerine and nonpasserine birds using conventional and phylogenetic methods. (silverchair.com)
Oxidative1
- Oxygen deprivation in newborns leads to hypoxic-ischemic encephalopathy, whose hallmarks are oxidative/nitrosative stress, energetic metabolism alterations, nutrient deficiency, and motor behavior disability. (hindawi.com)
Energy5
- The calculation of respiratory exchange ratio from the quotient of CO 2 produced and O 2 consumed gives information about the preferred fuel used in energy metabolism. (mouseclinic.de)
- Most definitions of metabolism refer to it as the chemical (metabolic) processes inside cells that convert food and drink into usable energy so that the body can then carry out basic life functions. (bistromd.com)
- If, nonetheless, the CK reaction were rate limiting for high-energy phosphate transport underneath certain circumstances in vivo, regulation of CK activity might have an impact on energy metabolism. (justdoitsnow.com)
- These results demonstrate that the upregulation of energy metabolism induced by visual stimulation depends on the type of information processing taking place in V1, and that 1H-fMRS provides unique information about local input/output balance that is not measured by BOLD fMRI. (marbilab.it)
- The energy metabolism of cancer cells. (biomedcentral.com)
Hallmark1
- Reprogramming of cancer metabolism is a newly recognized hallmark of malignancy. (biomedcentral.com)
Hormones1
- All in all, the endocrine system regulates the rate and controls the direction of metabolism via chemical messengers known as hormones. (bistromd.com)
Metabolites1
- Although altered metabolism drives tumour progression, the spectrum of metabolites used as nutrients by PDA remains largely unknown. (biomed.news)
Profound1
- By virtue of their profound ability to suppress metabolism and core temperature, with body temperatures dropping below 0°C, AGS are known as 'extreme' hibernators ( Barnes, 1989 ). (elifesciences.org)
Radiation1
- Apart from the plesiosaur radiation, pistosauroids include the basal paraphyletic non-plesiosaurian forms, herein referred to as Pistosauridae. (peerj.com)
Determines1
- The totality of metabolism includes the following and determines how many total calories one needs to maintain basic health and an appropriate weight range. (bistromd.com)
Function3
- It is time to clarify the vague function known as metabolism once and for all! (bistromd.com)
- In contrast, radial nerve showed an unexpected level of complexity with the expression of 3,370 genes significantly altered more than two-fold with age, including genes involved in nerve function, signaling, metabolism, transcriptional regulation and chromatin modification. (nature.com)
- Senter P. Analysis of forelimb function in basal ceratopsians. (isbweb.org)
Temperatures1
- We hypothesize that the increased metabolism and higher body temperatures of bats during flight might serve as an evolutionary adjuvant to their immune systems, providing a powerful selective force against virulence and promoting the diversity of viruses that infect bat populations. (cdc.gov)
Increases2
- Using vascular canal diameter, derived from osteohistological thin-sections, we show that inferred red blood cell size significantly increases in pistosauroids compared to more basal sauropterygians. (peerj.com)
- Inducing sleep and delta activity by adenosine infusion into basal forebrain during the normally active dark period also increases ATP. (jneurosci.org)
Level2
- Cancer cells often maintain high basal level of ROS and are vulnerable to any further increase in ROS levels beyond a certain protective threshold. (degruyter.com)
- This is because cancer cells maintain high basal level of ROS, thus they are vulnerable to any further increase in ROS (Fig. 1 ). (degruyter.com)
Losing weight1
- In a body-focused culture, it is common to spend endless hours researching how to increase metabolism in hopes of losing weight. (bistromd.com)
Pattern1
- Heldmaier G and Steinlechner S (1981) Seasonal pattern and energetics of short daily torpor in the djungarian hamster, Phodopus sungorus. (mouseclinic.de)
Cancer cells1
- Redirection of glutamine to cellular energetics destabilizes glutathione homeostasis in glioblastoma cells and other cancer cells [ 9 ]. (degruyter.com)
Journal2
- Journal of Cerebral Blood Flow and Metabolism (42):844-860. (marbilab.it)
- Standard metabolism of monotremes and the evolution of homeothermy , Australian Journal of Zoology , vol. (allenpress.com)
Common1
- Plasma metabolite concentrations and labeling enrichments are common measures of organismal metabolism. (biomed.news)
Unique1
- This natural inter-dependency between core microglial properties and metabolism offers a unique opportunity to modulate microglial activities via nutritional or metabolic interventions. (biomedcentral.com)
Activity1
- Ultimately, metabolism is a delicate balancing act between anabolic and catabolic activity. (bistromd.com)
Natural1
- First of all, the human body possesses many natural regulators of metabolism that try to keep it as close to equilibrium or homeostasis as possible. (bistromd.com)
Center1
- Metabolism is likely in the center of the search but its role is vital to health beyond weight loss. (bistromd.com)
Groups1
- The pink bar denotes basal eosauropterygian groups (Pachypleurosauridae, Nothosauroidea) from coastal and shallow-water habitats. (peerj.com)
Muscle1
- The trauma/injury to the muscle fibers activates satellite cells, which are exterior to the muscle fibers between the basement membrane (basal lamina) and the plasma membrane (sarcolemma) of muscles fibers. (nfpt.com)