• Pulmonary fibrosis and chronic lung inflammation in ET-1 transgenic mice," American Journal of Respiratory Cell and Molecular Biology , vol. 23, no. 1, pp. 19-26, 2000. (hindawi.com)
  • L. Guembe and A. C. Villaro, "Immunohistochemical mapping of endothelin in the developing and adult mouse lung," Journal of Histochemistry and Cytochemistry , vol. 49, no. 10, pp. 1301-1309, 2001. (hindawi.com)
  • Hypothesis: Pulmonary-vascular remodeling in infants developing BPD is directly related to circulating pro-endothelin-1, which therefore serves as surrogate marker of BPD. (clinicaltrials.gov)
  • Although alterations in ET-1 system components are observed in some studies, there remains a need for future research to clarify whether these specific changes are compensatory or causally related to vascular injury and dysfunction. (springer.com)
  • Furthermore ET-1 was able to enhance HUVEC differentiation into cord vascular-like structures on Matrigel. (nih.gov)
  • Studies suggest that this antibody binds to an epitope in the region of ET-1 represented by amino acids 8-16. (abcam.com)
  • Six of 20 histologically normal appendixes from patients with a clinical diagnosis of acute appendicitis had many ET-1-positive stromal cells and high pp-ET-1 mRNA expression, similar to inflamed appendix. (physiology.org)
  • Increased mortality with elevated plasma endothelin-1 in acute heart failure: an ASCEND-HF biomarker substudy. (nih.gov)
  • We aimed to determine the association between serial ET-1 levels and acute heart failure patient outcomes. (nih.gov)
  • We measured plasma ET-1 at baseline, 48-72 h, and 30 days in a cohort of 872 patients hospitalized with acute heart failure from the ASCEND-HF trial (randomized to nesiritide vs. placebo), and its association with 30-day mortality, 180-day mortality, in-hospital death or worsening heart failure, and 30-day mortality or rehospitalization. (nih.gov)
  • We observed an independent association between elevated ET-1 and short-term in-hospital clinical outcomes and 180-day mortality in hospitalized patients with acute heart failure ET-1 provided additional prognostic information which was incremental to that yielded by NT-proBNP. (nih.gov)
  • Endothelin-1 secretion by alveolar macrophages in systemic sclerosis," American Journal of Respiratory and Critical Care Medicine , vol. 156, no. 5, pp. 1429-1435, 1997. (hindawi.com)
  • ab2786 labelling Endothelin 1 (green) in the secretion of HeLa cells (right) compared with a negative control (left) by Immunocytochemistry/Immunofluorescence. (abcam.com)
  • The ET(B) receptor (ET(B)R) antagonist, BQ 788, blocked the angiogenic effects induced by ET-1, whereas the ET(A)R antagonist was less effective. (nih.gov)
  • Continued administration of pembrolizumab for adenocarcinoma of the lung after the onset of fulminant type 1 diabetes mellitus as an immune-related adverse effect: A case report. (bioportfolio.com)
  • Lactoferrin-endothelin-1 axis contributes to the development and invasiveness of triple-negative breast cancer phenotypes. (ptglab.com)
  • Furthermore, addition of exogenous PIP 2 , but not PIP 3 , restored insulin-regulated GLUT4 translocation and glucose transport impaired by ET-1. (diabetesjournals.org)
  • The corrective effect of exogenous PIP 2 in ET-1-induced insulin-resistant cells was not present in cells where cortical F-actin remained experimentally depolymerized. (diabetesjournals.org)
  • The central administration of endothelins modulates endocrine and cardiovascular regulation and behavior ( van den Buuse, 1997 ). (frontiersin.org)
  • Proliferative effect of ET-1 and VEGF on HUVEC. (nih.gov)
  • Forty percent of the pp-ET-1 mRNA-expressing cells were neutrophils, and the other positive cells were mast cells and macrophages. (physiology.org)
  • Moreover, further research may test the efficacy of selective ET-1 pharmacological interventions (e.g. (springer.com)
  • The aims of this study were to examine the expression level of SCUBE2 in T2DM patients with dyslipidemia and its correlation with endothelial dysfunction marker, endothelin-1 (ET-1) in this group. (bioportfolio.com)
  • We used immunohistochemistry and in situ hybridization to detect the presence, distribution, and phenotype of ET-1-positive cells and prepro-ET-1 (pp-ET-1) mRNA-expressing cells. (physiology.org)
  • ET-1-positive stromal cells and pp-ET-1 mRNA-expressing cells were detected with different distributions and relative frequencies in normal control appendix, histologically normal appendix, and inflamed appendix. (physiology.org)
  • ET-1 stimulated matrix metalloproteinase-2 mRNA expression and metalloproteinase-2 production, as determined by reverse transcriptase-polymerase chain reaction and gelatin zymography. (nih.gov)
  • ET-1 mRNA was analyzed by reverse transcriptase-polymerase chain reaction (RT-PCR) technique. (hindawi.com)