AnatomyDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPsychiatry and PsychologyPhenomena and ProcessesHealth Care
Coronary VasospasmVasospasm, IntracranialAngina Pectoris, VariantErgonovineCoronary VesselsCoronary AngiographyEndothelium, VascularVasodilator AgentsIsosorbide DinitrateCoronary Artery DiseaseElectrocardiographySubarachnoid HemorrhageAcetylcholineCoronary CirculationVasodilationVasoconstrictionDiltiazemAngioplasty, Balloon, CoronaryCoronary StenosisNitratesMyocardial InfarctionAngina PectorisCalcium Channel BlockersCoronary Artery Bypassrho-Associated KinasesCardiac CatheterizationNitric OxideNitric Oxide Synthase Type IIICoronary DiseaseBrachial ArteryNitroglycerinBasilar ArteryNitroprussideVascular DiseasesOxidative StressRisk FactorsCoronary AneurysmCoronary ThrombosisEndothelial CellsBiological MarkersTime FactorsVentricular Dysfunction, LeftBlood PressureRegional Blood FlowErectile DysfunctionAortaSuperoxidesBlood Flow VelocityDisease Models, AnimalTreatment OutcomeIschemic Attack, TransientPapaverineVasomotor SystemNitric Oxide SynthaseHyperemiaForearmCerebral AngiographyProspective StudiesMicrocirculationHypertensionVasoconstrictor AgentsCoronary RestenosisAtherosclerosisArginine
ArteriesAngiographyPercutaneous coronary intObstructive coronary arteryBypassMyocardial infarctionAtherosclerosisAcuteArterialAnginaPathophysiologyGraftMicrovascularSpasmCases of coronaryOcclusionNitricIschemiaProgenitor cellsMyocardiumReactivityThrombosisCardiovascularInduceSaphenousVasoconstrictionDiastolic dysfunctionDiseaseHyperreactive to vasoconstrictor stimuliSystemicCardiacHemodynamicLeft ventricularVasoconstrictorHypertensionPhysiologicalBlood vesselMigraineCerebralRefersEndotheliumPathogenesisSymptomsCoagulationChronicMorphologyOccurPathway
Arteries21
  • A subsequent study distinguished this type of angina from classical angina pectoris further by showing normal coronary arteries on cardiac catheterization. (wikipedia.org)
  • For example, cocaine use can trigger vasospasm in coronary arteries through its actions on adrenergic receptors causing vasoconstriction. (wikipedia.org)
  • Ultimately, when large coronary arteries undergo vasospasm, this can lead to either complete or transient occlusion of blood flow within the artery. (wikipedia.org)
  • OBJECTIVES: We investigated psychosocial factors in women with myocardial infarction with nonobstructive coronary arteries (MINOCA) and those with MI and obstructive coronary artery disease (CAD). (bvsalud.org)
  • Exposure of isolated bovine coronary arteries to high glucose (30 mmol/l d -glucose) but not to osmotic control mannitol (30 mmol/l) switched angiotensin II-stimulated prostacyclin (PGI 2 )-dependent relaxation into a persistent vasoconstriction that was sensitive to either indomethacin, a cyclooxygenase inhibitor, or SQ29548, a selective thromboxane receptor antagonist. (diabetesjournals.org)
  • These studies documented normal cardiac function and normal morphology of the coronary arteries. (biomedcentral.com)
  • There is an important distinction between ANOCA (angina with nonobstructive coronary arteries) and INOCA (ischemia with nonobstructive coronary arteries). (acc.org)
  • In particular, the condition occurs when the coronary arteries are blocked hence limiting their ability to supply oxygenated blood to the heart muscles. (homeworkmarkets.com)
  • Mills, N.L. and Ochsner, J.L. (1975) Preparations of Internal Mammary Arteries for Coronary Bypass with Intraluminal Papaverine. (scirp.org)
  • Coronary Arteries Spasm (CAS) is a cardiovascular entity characterized by chest pain at rest with temporary electrocardiographic (ECG) ischemic ST-segment changes with a prompt response to nitrates. (acquaintpublications.com)
  • These symptoms are attributed to coronary arteries spasm [1] . (acquaintpublications.com)
  • The pathophysiology of coronary arteries spasm results from the interaction of 2 components: (1) It is a usually localized, but sometimes diffuse, abnormality of a coronary artery that makes it hyperreactive to vasoconstrictor stimuli, and (2) There is a vasoconstrictor stimulus able to induce the spasm at the level of the hyperreactive coronary segment [3] . (acquaintpublications.com)
  • Overview of Coronary Artery Disease Coronary artery disease (CAD) involves impairment of blood flow through the coronary arteries, most commonly by atheromas. (msdmanuals.com)
  • The mechanisms of vascular dysfunction have been investigated in a number of conditions, including hypertension 13 and diabetes, 14 using subcutaneous arteries isolated from biopsies of gluteal fat. (bmj.com)
  • This approach has the advantage of studying vascular dysfunction directly in arteries from patients (rather than animal models) and uses resistance arteries which contribute significantly to maintenance of blood pressure. (bmj.com)
  • Myocardial bridging occurs when coronary arteries run intramurally. (ecrjournal.com)
  • His work on Ejection fraction, Artery and Coronary arteries as part of general Cardiology study is frequently linked to In patient, bridging the gap between disciplines. (research.com)
  • Aspirin therapy have serious side effects include,requires greater your nervous system plays an implantable neurostimulators is an anomalous coronary arteries may worsen but they can reduce the incoming blood moving as well as a general public service. (marpsicologia.es)
  • Compared to Internal Thoracic Arteries (ITA) Human Saphenous Veins (HSV) demonstrate worse patency when used for Coronary Artery Bypass Grafting (CABG) [ 5 , 6 ]. (longdom.org)
  • Patent venous grafts are even associated with an increased risk of disease progression in the native coronary arteries compared with patent arterial grafts [ 13 ]. (longdom.org)
  • Macroscopically unchanged Human Saphenous Veins (HSV, 10-20 mm long, inner diameter 1-3 mm) were obtained from 54 patients (40 male, 14 female) during Coronary Arteries Bypass Grafting (CABG) procedure before implantation and from surgical removal of varicose veins. (longdom.org)
Angiography9
  • He was diagnosed with effort angina by coronary angiography and underwent DES implantation in the mid-left ascending artery (LAD) after the administration of dual anti-platelet therapy. (biomedcentral.com)
  • His baseline electrocardiogram (ECG) and echocardiography were normal, but coronary angiography (CAG) revealed intermediate stenosis in the left ascending artery (LAD) and left circumflex artery (LCx). (biomedcentral.com)
  • Only three cases of coronary artery disease related to sorafenib therapy have been described in the literature, and all were due to arterial vasospasm without evidence of coronary artery stenosis on angiography. (biomedcentral.com)
  • A 58-year-old man with mRCC developed acute coronary syndrome (ischemia/infarction) associated with critical sub-occlusion of the common trunk of the left coronary artery and some of its branches, which was documented on coronary angiography. (biomedcentral.com)
  • Cardiac function was investigated, including coronary angiography and transthoracic and transesophageal echocardiography. (biomedcentral.com)
  • Results of the Clopidogrel After Surgery for Coronary Artery Disease (CASCADE) trial confirmed that this practice independently associated with improved graft patency, as demonstrated by coronary angiography and saphenous vein graft intravascular ultrasonography. (medscape.com)
  • The present diagnostic paradigm in patients with angina pectoris is focused on likelihood and subsequent identification of obstructive CAD PATHOPHYSIOLOGIC BASIS (3, 4), but most patients referred for assessment do not fulfill criteria for invasive coronary angiography (ICA), and in the Under resting conditions, the coronary blood flow is kept subset of patients ultimately examined with ICA, many patients, constant at varying coronary pressures. (readkong.com)
  • Retinal microcirculation can be directly imaged by optical coherence tomography angiography (OCTA) during perfusion-deficit states such as sepsis, and other systemic haemodynamic disturbances such as acute coronary syndrome, and systemic inflammatory conditions such as inflammatory bowel disease. (springeropen.com)
  • Angiographic evaluation of the radial artery diameter in patients who underwent coronary angiography or coronary intervention. (trico.guru)
Percutaneous coronary int7
  • Although drug-eluting stents (DES) reduce restenosis after percutaneous coronary intervention (PCI) more effectively than bare-metal stents (BMS), there are a variety of DES-related complications, such as coronary artery vasospasm. (biomedcentral.com)
  • [ 53 ] The risk for MI was reduced after percutaneous coronary intervention and noncardiac surgical procedures, but not for coronary artery bypass grafting (CABG). (medscape.com)
  • Influence of Arterial Access Site Selection on Outcomes in Primary Percutaneous Coronary Intervention: Are the Results of Randomized Trials Achievable in Clinical Practice? (trico.guru)
  • Anticoagulation in transradial percutaneous coronary intervention. (trico.guru)
  • Adoption of radial access and comparison of outcomes to femoral access in percutaneous coronary intervention: an updated report from the national cardiovascular data registry (2007-2012). (trico.guru)
  • Our article discusses few of the patents related to strategies for preventing slow-flow/no-reflow phenomenon in SVG percutaneous coronary intervention (SVG PCI). (eurekaselect.com)
  • We propose a patent to this 3-step strategy of percutaneous coronary intervention of SVG lesions not associated with thrombus. (eurekaselect.com)
Obstructive coronary artery4
  • BACKGROUND: Global longitudinal strain (GLS) is a sensitive marker for identifying subclinical myocardial dysfunction in obstructive coronary artery disease (CAD). (bvsalud.org)
  • Patients with ANOCA tend to be younger, have fewer risk factors than those with obstructive coronary artery disease, and are more likely to be women. (acc.org)
  • REVIEW published: 29 October 2021 doi: 10.3389/fcvm.2021.723542 Doppler Echocardiography Assessment of Coronary Microvascular Function in Patients With Angina and No Obstructive Coronary Artery Disease Jakob Schroder* and Eva Prescott Department of Cardiology, Bispebjerg Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark Edited by: Echocardiographic evaluation is an essential part of the diagnostic work-up in Tim van de Hoef, Academic Medical patients with known or suspected cardiovascular disease. (readkong.com)
  • In the absence of obstructive coronary artery disease, Andreas Seitz, Robert Bosch Hospital, Germany low TTDE-derived coronary flow velocity reserve (CFVR) is considered a marker of Gaetano Antonio Lanza, coronary microvascular dysfunction (CMD). (readkong.com)
Bypass9
  • The patient underwent triple coronary artery bypass surgery, and sorafenib treatment was discontinued. (biomedcentral.com)
  • Tector, A.J., Schmahl, T.M. and Canino, V.R. (1983) The Internal Mammary Artery Graft: The Best Choice for Bypass of the Diseased Left Anterior Descending Coronary Artery. (scirp.org)
  • Kong, B., Kopelman, H., Segal, B.L. and Iskandrian, A.S. (1988) Angiographic Demonstration of Spasm in a Left Internal Mammary Artery Used as a Bypass to the Left Anterior Descending Coronary Artery. (scirp.org)
  • Tanaka, N. (2009) Pharmacological Studies on Responsiveness of 5-Hydroxytryptamine in Overcoming Perioperative Spasm of Coronary Artery Bypass Graft. (scirp.org)
  • Medication is the first-line therapy, while surgical de-roofing and coronary bypass are reserved for severe stenosis. (ecrjournal.com)
  • Coronary artery bypass graft (CABG) surgery is a procedure to revascularize ischemic myocardium. (gentaurpub.com)
  • This finding might contribute to elucidate the patency of saphenous veins when used as coronary artery bypass. (longdom.org)
  • Handling, storage solution and distension to overcome spasm and identify leaking branches have been suggested to be responsible for the thrombosis, neointimal hyperplasia and atherosclerosis that contribute to vein graft failure in Coronary Artery Bypass Graft (CABG) operations [ 11 , 14 , 15 ]. (longdom.org)
  • By contrast, the ITA never has been exposed to those forces and show little if any evidence of atherosclerosis when used for Coronary Artery Bypass Grafting (CABG). (longdom.org)
Myocardial infarction4
Atherosclerosis7
Acute17
  • The past 4 decades have witnessed tremendous progress in the areas of acute cardiac care, coronary care unit expansion, thrombolytic usage, and PCI. (medscape.com)
  • Acute coronary syndrome is caused by lack of adequate blood in the heart. (homeworkmarkets.com)
  • In 2006 alone, more than 1.4 million patients were discharged with a primary or secondary diagnosis of acute coronary syndrome. (homeworkmarkets.com)
  • Following a discharge, patients suffering from acute coronary syndrome require re-hospitalization within the first six months. (homeworkmarkets.com)
  • In total, acute coronary syndrome accounts for half of all mortality related to cardiovascular diseases. (homeworkmarkets.com)
  • The cost of rehabilitating patients with acute coronary syndrome is enormous. (homeworkmarkets.com)
  • The direct costs of treatment are estimated to be $75 billion while the indirect costs of treating patients with acute coronary syndrome are more than $142 billion. (homeworkmarkets.com)
  • A number of studies have been conducted to examine the threat of Acute Coronary Syndrome among the American population. (homeworkmarkets.com)
  • Using self-reported data, the researchers found out that the Southern Eastern states are the ones that are heavily affected by the Acute Coronary Syndrome menace. (homeworkmarkets.com)
  • Due to the high prevalence rates, death rates as a result of Acute Coronary Syndrome are also significantly higher, in the southeastern regions, compared to the other parts around the nation. (homeworkmarkets.com)
  • Acute Coronary Syndrome has affected other developed countries. (homeworkmarkets.com)
  • In the UK, Acute Coronary Syndrome is a leading cause of disability, and a leading cause of death. (homeworkmarkets.com)
  • Currently, there are around 1 million Acute Coronary Syndrome survivors while an estimated 150,000 people are diagnosed with Acute Coronary Syndrome every year. (homeworkmarkets.com)
  • The majority of those affected by Acute Coronary Syndrome in the UK are the elderly and the leading risk factor is obesity. (homeworkmarkets.com)
  • The levels of activity among the residents in these four countries are also very low and this explains why Acute Coronary Syndrome is responsible for a significant percentage of deaths that are reported in the country. (homeworkmarkets.com)
  • A 45-year-old married, officer, heavy smoker, Egyptian male patient presented with acute excruciating severe chest pain and combined electrocardiographic ST-segment coronary artery spasms. (acquaintpublications.com)
  • Overall, £ 8 billion is spent in Acute Coronary Syndrome-related costs. (smartacademicwriting.com)
Arterial5
  • The cardiotoxic effects of sorafenib and sunitinib may cause hypertension, left ventricular ejection fraction (LVEF) dysfunction and/or congestive heart failure (CHF), and arterial thrombo-embolic events (ATE). (biomedcentral.com)
  • Serum lipid abnormalities have been noted as important risk factors in a variety of vascular disorders such as coronary artery disease, ischemic stroke, and peripheral arterial disease. (surgicalneurologyint.com)
  • Endothelial health depends on arterial flow patterns, given that the vessel reacts differently to various flow types, as confirmed in 3D simulations. (ecrjournal.com)
  • Endothelial function is not uniform throughout the arterial system. (hindawi.com)
  • Endothelial cells' F-actin pattern and nitric oxide (NO) secretion are modulated accordingly by the arterial stretch. (gentaurpub.com)
Angina10
  • described a type of chest pain resulting from coronary vasospasm, referring to it as a variant form of classical angina pectoris. (wikipedia.org)
  • Coronary vasospasm classically produces chest pain at rest, also known as vasospastic angina. (wikipedia.org)
  • Unlike classical angina pectoris, traditional cardiovascular risk factors are not thought to be significantly associated with coronary vasospasm. (wikipedia.org)
  • Therefore, we should monitor new-onset rest angina after stent implantation and carefully assess DES-induced coronary vasospasm. (biomedcentral.com)
  • Pharmacotherapy for coronary microvascular dysfunction: Exercise training, mental relaxation, weight loss, and cardiac rehabilitation have been associated with improvements in symptoms, exercise capacity, time to angina, and quality of life (QoL). (acc.org)
  • Association with symptoms and prognosis, Doppler Echocardiography comparison with alternative invasive and non-invasive imaging modalities, and possible Assessment of Coronary Microvascular Function in Patients interventions in angina patients with low CFVR were discussed, and key research With Angina and No Obstructive questions were proposed. (readkong.com)
  • Schroder and Prescott CFVR in Non-obstructive Angina INTRODUCTION and prognosis, comparison with alternative invasive and non- invasive imaging modalities, and possible interventions in angina Coronary artery disease remains one of the leading causes of patients with low CFVR were discussed. (readkong.com)
  • Ultimately, only a coronary blood flow is increased due to a simultaneous increase fraction of angina patients is treated with revascularization (5- in coronary perfusion pressure and a decrease in coronary 7). (readkong.com)
  • Because myocardial oxygen demand is determined mainly by heart rate, systolic wall tension, and contractility, narrowing of a coronary artery typically results in angina that occurs during exertion and is relieved by rest. (msdmanuals.com)
  • His Angina, Ejection fraction, Chest pain and Ischemia study, which is part of a larger body of work in Cardiology, is frequently linked to Vasospasm, bridging the gap between disciplines. (research.com)
Pathophysiology3
  • The exact pathophysiology behind coronary vasospasm has not been elucidated. (wikipedia.org)
  • Several mechanisms that may cause ischemic stroke in migraine have been described, of which CSD-induced endothelial dysfunction is the primary pathophysiology of ischemic stroke in migraine. (springeropen.com)
  • Cerebral endothelial dysfunction is mentioned in the pathophysiology of several neurological diseases. (hindawi.com)
Graft2
  • A small-diameter vascular graft immobilized peptides for capturing endothelial colony-forming cells. (gentaurpub.com)
  • 2277 related Products with: A small-diameter vascular graft immobilized peptides for capturing endothelial colony-forming cells. (gentaurpub.com)
Microvascular4
  • The absence does not exclude the presence of coronary microvascular dysfunction. (acc.org)
  • These patients benefit from a multidisciplinary care team that includes an interventional cardiovascular disease specialist with expertise in coronary microvascular dysfunction assessment, provocative testing for coronary spasm and myocardial bridge testing, and a noninvasive cardiologist with expertise in noninvasive ANOCA testing. (acc.org)
  • Pharmacotherapy for coronary spasm: CCBs should be used first-line for epicardial coronary spasm and may be beneficial for microvascular spasm. (acc.org)
  • Slow flow and no-reflow phenomenon (SF-NR) in saphenous vein grafts (SVG) stenting is related to the occurrence of distal plaque embolization, platelet activation and microvascular vasospasm. (eurekaselect.com)
Spasm1
Cases of coronary3
Occlusion4
  • Coronary vasospasm refers to when a coronary artery suddenly undergoes either complete or sub-total temporary occlusion. (wikipedia.org)
  • When coronary vasospasm occurs, the occlusion temporarily produces ischemia. (wikipedia.org)
  • [2] . The term of CAS refers to sudden, intense vasoconstriction of an epicardial coronary artery that causes vessel occlusion or near occlusion [3] . (acquaintpublications.com)
  • Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion. (ucsd.edu)
Nitric5
  • Specifically, these agents work by enhancing the production of nitric oxide from endothelial nitric oxide synthase. (wikipedia.org)
  • Endothelial dysfunction wherein there is a deficiency in the production of nitric oxide has been found to be associated with coronary vasospasm in some but not all cases. (wikipedia.org)
  • Vasodilatory agents with mechanisms dependent on a functional endothelial nitric oxide synthase can cause vasoconstriction instead in the setting of endothelial dysfunction, leading to coronary vasospasm. (wikipedia.org)
  • In the present study, we aimed to study the roles of endothelial nitric oxide synthase (eNOS) in diabetes. (diabetesjournals.org)
  • There is an overwhelming mass of evidence demonstrating the development of endothelial dysfunction in animal models of diabetes and in human blood vessels from diabetic patients, as evidenced by increased release of reactive oxygen species, decreased nitric oxide (NO) bioactivity, decreased release of prostacyclin (PGI 2 ), and enhanced endothelial production of vasoconstrictor thromboxane (Tx)A 2 /prostaglandin (PG)H 2 in early stages of diabetes ( 1 - 3 ). (diabetesjournals.org)
Ischemia2
  • However, secondary RaynaudпїЅs is characterized by vasospasm and stuck blood vessel obstructions that may result in ischemia, ulceration, and gangrene. (ehd.org)
  • 5 28 ] This is principally due to the occurrence of delayed cerebral ischemia (DCI) or vasospasm. (surgicalneurologyint.com)
Progenitor cells2
  • Endothelial microparticles (EMP), endothelial progenitor cells (EPCs), high-sensitivity CRP (hs-CRP), and endothelin-1 are some of the biomarkers that indicate endothelial dysfunction in migraine (ET-1) [ 5 ]. (springeropen.com)
  • We have discovered unique adult stem cells in mouse tissues termed Endothelial-Macrophage (EndoMac) progenitor cells that give rise to both macrophages and endothelial cells and contribute to blood vessel formation after tissue injury. (edu.au)
Myocardium1
  • As the myocardium becomes ischemic, coronary sinus blood pH falls, cellular potassium is lost, lactate accumulates, ECG abnormalities appear, and ventricular function (both systolic and diastolic) deteriorates. (msdmanuals.com)
Reactivity4
  • Several important points of the cause of stroke in migraine are hemodynamic changes, endothelial dysfunction, cervical artery dissection, vascular reactivity, hypercoagulability, and abortive migraine drugs. (springeropen.com)
  • According to Balasubramaniam, Viswanathan, Marshall and Zaman (2012) endothelial dysfunction is characterized by an imbalance between vasodilating and vasoconstricting substances, and an increase in leucocyte adhesion, hence leading to vascular reactivity. (homeworkmarkets.com)
  • In this review, the role of cerebrovascular reactivity to L-arginine (CVR-L-Arg) for assessment of cerebral endothelial function is discussed. (hindawi.com)
  • In the past few years cerebrovascular reactivity to L-arginine by means of TCD has emerged as a parameter for evaluation of cerebral endothelial function [ 3 - 7 ]. (hindawi.com)
Thrombosis2
  • We report a case in which DES-induced severe coronary vasospasm was clinically suspected as a cause of subacute stent thrombosis (ST). (biomedcentral.com)
  • In the present study, an electrospinning poly (L)-lactic acid (PLLA) bilayered scaffold is developed to prevent thrombosis after implantation by promoting the capture and differentiation of endothelial colony-forming cells (ECFCs). (gentaurpub.com)
Cardiovascular5
  • Coronary vasospasm increases the risk of life-threatening cardiovascular events. (biomedcentral.com)
  • Endothelial dysfunction is a hallmark of vascular injury in diabetes and is preceded by the development of overt cardiovascular diseases ( 1 - 3 ). (diabetesjournals.org)
  • Cardiotoxicity is commonly associated with the presence of cardiovascular risk factors, such as a history of hypertension or coronary artery disease. (biomedcentral.com)
  • Inhibition of the ROCK pathway not only has great promise for treating glaucoma, but also has therapeutic potential for cardiovascular and pulmonary diseases, prostate cancer, neurological disorders and corneal endothelial wound healing. (reviewofoptometry.com)
  • It has been proposed that vascular dysfunction contributes to the pathogenesis of glaucoma and, in particular, NPG as this condition is associated with the presence of widespread cerebrovascular and systemic cardiovascular disease. (bmj.com)
Induce2
  • For invasive testing, patient preparation and vascular access are important to focus on and specific drugs are used such as adenosine to induce hyperemia and acetylcholine to induce vasospasm and endothelial dysfunction. (acc.org)
  • Recently, we have shown that blood flow patterns at vein valves induce oscillatory stress genes, which maintain an anticoagulant endothelial phenotype that inhibits spontaneous clotting at vein valves and sinuses, is lost in the presence of DVT in human pathological samples, and is dependent on expression of the transcription factor FOXC2. (gentaurpub.com)
Saphenous2
  • Human Saphenous Vein Endothelial Cell Isolation and Exposure to Controlled Levels of Shear Stress and Stretch. (gentaurpub.com)
  • Here, we describe the isolation, characterization, and expansion of human saphenous vein endothelial cells (hSVECs). (gentaurpub.com)
Vasoconstriction1
Diastolic dysfunction1
  • Hypertrophic Cardiomyopathy Hypertrophic cardiomyopathy is a congenital or acquired disorder characterized by marked ventricular hypertrophy with diastolic dysfunction (eg, due to valvular aortic stenosis, coarctation. (msdmanuals.com)
Disease10
Hyperreactive to vasoconstrictor stimuli1
  • In general, it is thought that an abnormality within a coronary artery causes it to become hyperreactive to vasoconstrictor stimuli. (wikipedia.org)
Systemic2
  • Conclusions: This study has identified dysfunction of the systemic vascular endothelial cell in patients with normal pressure glaucoma. (bmj.com)
  • CVR-L-Arg has been compared to flow-mediated dilatation as a gold standard for systemic endothelial function and intima-media thickness as a marker for morphological changes. (hindawi.com)
Cardiac1
  • The assessment of coronary flow reserve (CFR) by cardiac magnetic resonance or positron emission tomography has a Class 2a recommendation in symptomatic patients in the 2021 multisociety guideline for the evaluation and diagnosis of chest pain. (acc.org)
Hemodynamic1
  • In summary, we present a detailed method to isolate hSVECs to study the influence of hemodynamic mechanical stress on an endothelial phenotype. (gentaurpub.com)
Left ventricular1
  • Long-term alcohol use has been implicated as the etiology of left ventricular (LV) dysfunction in as many as one third of cases of dilated cardiomyopathy . (medscape.com)
Vasoconstrictor1
  • If and when vasoconstrictor stimuli act upon the hyperreactive segment of the artery, then vasospasm can result. (wikipedia.org)
Hypertension2
Physiological3
  • Critical illness with multiple organ dysfunction is characterised by complex physiological and metabolic responses requiring support and optimisation of organ systems in the intensive treatment unit (ITU) [ 1 ]. (springeropen.com)
  • In conclusion CVR-L-Arg is a promising noninvasive research method that could provide means for evaluation of cerebral endothelial function in physiological and pathological conditions. (hindawi.com)
  • Endothelial cells are highly metabolically active and play an important role in many physiological functions, including the control of vasomotor tone, blood cell trafficking, haemostatic balance, permeability, proliferation, and immunity. (hindawi.com)
Blood vessel1
Migraine2
  • In migraine, endothelial dysfunction plays a part in the stroke process. (springeropen.com)
  • So far CVR-L-Arg has been used to study cerebral endothelial function in many pathological conditions such as stroke, migraine, etc. (hindawi.com)
Cerebral3
  • However, it seems to show specific cerebral endothelial function. (hindawi.com)
  • Until recently it was impossible to determine specific cerebral endothelial function. (hindawi.com)
  • However, these techniques do not enable any evaluation of cerebral endothelial function. (hindawi.com)
Refers1
  • Endothelial dysfunction refers to a condition whereby the inner linings of the endothelium fail to function properly. (homeworkmarkets.com)
Endothelium1
  • Some of the factors that have been proposed to contribute to coronary vasospasm include the following: Endothelial dysfunction Certain vasodilatory agents exert their effects by working via the endothelium, the cells that make up the lining of blood vessels. (wikipedia.org)
Pathogenesis1
  • Aim: Vascular risk factors, and particularly vasospasm, are thought to play a part in the pathogenesis of normal pressure glaucoma (NPG). (bmj.com)
Symptoms1
  • Coronary vasospasm is also associated with symptoms of fatigue and tiredness, dyspnea, and palpitations. (wikipedia.org)
Coagulation1
  • Platelets, endothelial cells, and leukocytes become activated and, in turn, initiate the coagulation cascade while releasing various mediators. (medscape.com)
Chronic1
  • Chronic inflammation due to smoking has been shown to be damaging to endothelial cell function. (wikipedia.org)
Morphology1
  • Cells isolated by collagenase digestion display the typical cobblestone morphology and express endothelial cell markers CD31 and VE-cadherin. (gentaurpub.com)
Occur1
  • Ideally, management of patients with ANOCA should occur at centers with coronary function testing expertise that can appropriately identify, test, and treat these complex patients, and improve care by integrating expert clinical staff, invasive and noninvasive diagnostic modalities, and clinical resources to ensure high-quality longitudinal follow-up. (acc.org)
Pathway2
  • In the eye, inhibiting the ROCK pathway with RKIs is thought to lower IOP by inducing cellular relaxation and disrupting focal adhesions in the TM and the inner wall endothelial lining of Schlemm's canal. (reviewofoptometry.com)
  • Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness. (gentaurpub.com)