Endothelial dysfunction aorta rats zucker. Medical search. Frequent questions

Endothelial dysfunction, as an early pivotal event in cardiovascular disease, is strongly associated with the pathogenesis of DM [ 1 , 2 ]. (hindawi.com)
The present study examined the combined effects of an antihypertensive (S-Amlodipine) and an insulin-sensitizing agent, peroxisome proliferator-activated receptor (PPAR) agonists (Pioglitazone and Ragaglitazar), on cardiovascular risk factors in aged diabetic and insulin-resistant Zucker fa/fa rats. (biomedcentral.com)
attain up your e-learning question agonists with Articulate Storyline Storyline has a other e-learning providing rat that has you to Want your scene to the cardiovascular bank. (quietisolation.de)

In conclusion, this study demonstrates that exenatide treatment can alleviate the vascular endothelial injury, as well as attenuating the nitrooxidative stress in hyperglycemia, implying that the endothelium-protective effect of exenatide might be related to the reduction of nitrooxidative stress. (hindawi.com)
PPAR-gamma agonists, also known as thiazolidinediones (TZDs), such as Pioglitazone and Rosiglitazone increase insulin sensitivity, reduce levels of blood glucose, insulin and triglycerides with a concomitant reduction in BP and improvement in endothelial function [ 8 , 9 ]. (biomedcentral.com)

Healthy male Wistar rats were randomly divided into 4 groups: control, diabetes mellitus (DM) model, low dose of exenatide treatment, and high dose of exenatide treatment. (hindawi.com)

In vitro study showed that, compared with control group, the DM rats exhibited a lowered endothelium-dependent relaxation and damaged structural integrity of thoracic aortas, and there was a significant increase in plasma nitrotyrosine concentration. (hindawi.com)

Endogenous thrombin potential (ETP) was increased in obese rats independent of platelets and age. (frontiersin.org)
ETP was increased at the surface of VSMCs from obese rats and addition of exogenous palmitic acid further enhanced ETP values. (frontiersin.org)
Gelatinase activity was increased in aorta at both ages in obese rats and MMP-2 activity was increased in VSMCs from obese rats. (frontiersin.org)
The aim of this study was to investigate the changes in cardiac stiffness, hepatic and renal function in high-carbohydrate, high-fat diet-induced obese rats following supplementation of red pitaya juice. (biomedcentral.com)
Nephrectomized aged Zucker obese rats were trained at a moderate (MOD) or high (INT) intensity or were. (researchgate.net)

Chronic diclofenac exposure increases mitochondrial oxidative stress, inflammatory mediators, and cardiac dysfunction. (nih.gov)
The complications includes obesity, increased fat accumulation in abdominal region, hypertension, insulin resistant, and impaired cardiac function, endothelial dysfunction as well as inflammation. (biomedcentral.com)

We examined the effects of 8 weeks of low intensity exercise training (LET) on metabolic, hemodynamic, ventricular and vascular morphological changes induced by fructose drinking in male rats. (biomedcentral.com)
Thus, the aim of this study was to evaluate the effects of 8 weeks of LET on metabolic, hemodynamic, as well as on cardiovascular and arterial morphological changes induced by fructose drinking in male rats. (biomedcentral.com)
This study only utilized male rats to avoid the influence of the oestrus cycle on food intake which may affect the diet-induced model [ 6 ]. (biomedcentral.com)

Role of Bone Morphogenetic Proteins-7 (BMP-7) in the Renal Improvement Effect of DangGui (Angelica sinensis) in Type-1 Diabetic Rats. (medscape.com)
The present study was designed to isolate and characterize triterpene components EAS and investigate the antihyperglycaemic effects alone or in combination with insulin in non-diabetic and streptozotocin (STZ)-induced diabetic rats. (endocrine-abstracts.org)

The mechanisms of action of many environmental agents commonly involve oxidative stress resulting from mitochondrial dysfunction. (nih.gov)

Aerobic exercise training (ET) may effectively mitigate fructose-induced hypertension in rats [ 13 ], and it has been acknowledged as a significant component in the treatment and prevention of human cardiovascular disease [ 14 ]. (biomedcentral.com)
The contribution of different forms of renovascular hypertension and the mechanisms contributing to autonomic dysfunction in hypertension are incompletely understood. (biomedcentral.com)

Male Wistar rats were divided into (n = 8 each) control (C), sedentary fructose (F) and ET fructose (FT) groups. (biomedcentral.com)
Fructose-drinking rats received D-fructose (100 g/l). (biomedcentral.com)

Also, there were a trend of uric acid and glucose normalization for HRP as compared to H-fed rats. (biomedcentral.com)

Our aim was to determine concomitant changes in thrombin generation in the blood compartment and at the surface of vascular smooth muscle cells (VSMCs) and its interplay with adipokines, free fatty acids (FFA), and metalloproteinases (MMPs) in obese Zucker rats that share features of the human MetS. (frontiersin.org)

Electroacupuncture of 2 hz has a rewarding effect: evidence from a conditioned place preference study in rats. (medscape.com)

Additionally, FT group presented improve of BS, numerical density of atrial natriuretic peptide granules (+42%) and LV capillaries (+25%), as well as the number of elastic lamellae in aorta compared with F group. (biomedcentral.com)

Total 48 male Wistar rats were divided into 4 groups: corn-starch group (CS), corn-starch + red pitaya juice group (CRP), high-carbohydrate, high fat group (HCHF) and high-carbohydrate, high fat + red pitaya juice (HRP). (biomedcentral.com)

Red pitaya has been shown to protect aorta from oxidative damage and improve lipid profiles in hypercholesterolemic rats probably due to phytochemicals content including phenolics and flavonoids. (biomedcentral.com)