Endothelial CellsCell AgingCells, CulturedUmbilical VeinsHuman Umbilical Vein Endothelial CellsEndotheliumEndothelium, VascularNeovascularization, PhysiologicCattleCell AdhesionAortaSignal TransductionVascular Endothelial Growth Factor AEndothelium, CornealCell MovementCyclin-Dependent Kinase Inhibitor p16CapillariesNeovascularization, PathologicCell ProliferationFibroblastsRNA, MessengerAntigens, CD31Cell LineVascular Cell Adhesion Molecule-1ApoptosisCell DivisionAgingMicrocirculationTumor Suppressor Protein p53Intercellular Adhesion Molecule-1TelomereE-SelectinGene Expression RegulationNitric Oxide Synthase Type IIIVascular Endothelial Growth Factor Receptor-2Nitric OxideUp-RegulationTelomerasePlant LeavesCell Adhesion Moleculesbeta-GalactosidaseBlotting, WesternCyclin-Dependent Kinase Inhibitor p21Time FactorsBlood VesselsEndothelial Growth FactorsReactive Oxygen SpeciesRNA, Small InterferingPhosphorylationOxidative StressReverse Transcriptase Polymerase Chain ReactionImmunohistochemistryMicrovesselsMice, Inbred C57BLAging, PrematureCell SurvivalVascular Endothelial Growth FactorsTumor Necrosis Factor-alphaCapillary PermeabilityDose-Response Relationship, DrugAngiogenesis InhibitorsLymphokinesStress, MechanicalDown-RegulationGene ExpressionEnzyme ActivationCell Line, TumorEnzyme InhibitorsCoculture TechniquesTransfectionvon Willebrand FactorReceptor, TIE-2Molecular Sequence DataMice, KnockoutDNA DamagePulmonary ArteryFibroblast Growth Factor 2PhenotypeRNA InterferenceHydrogen PeroxideModels, BiologicalFlow CytometryReceptors, Vascular Endothelial Growth FactorRetinal VesselsThrombinCulture Media, ConditionedEpoprostenolSwineNitric Oxide SynthaseCell CommunicationReceptors, Cell SurfaceCell CycleCaveolin 1Cell Line, TransformedInterleukin-8Antigens, CDNF-kappa BBase SequenceBlood-Brain BarrierMuscle, Smooth, Vascular