Endothelial CellsCell SurvivalEndothelium, VascularCells, CulturedUmbilical VeinsAngiopoietin-1Human Umbilical Vein Endothelial CellsApoptosisNeovascularization, PhysiologicVascular Endothelial Growth Factor AReceptor, TIE-2Endothelium, CornealSignal TransductionVascular Endothelial Growth Factor Receptor-2Angiopoietin-2Receptors, TIEEndothelial Growth FactorsCapillariesVascular Endothelial Growth FactorsSurvival RateNeovascularization, PathologicLymphokinesProto-Oncogene Proteins c-aktAngiogenesis InhibitorsCell MovementIntegrin alphaVbeta3PhosphorylationEndotheliumCattlePhosphatidylinositol 3-KinasesReceptors, Vascular Endothelial Growth FactorAortaEnzyme ActivationProto-Oncogene ProteinsProtein-Serine-Threonine KinasesFibroblast Growth Factor 2Cell DivisionCell LineEnzyme InhibitorsTransfectionRNA, MessengerReceptor Protein-Tyrosine KinasesBlotting, WesternDisease-Free SurvivalIntercellular Signaling Peptides and ProteinsMitogen-Activated Protein KinasesCell AdhesionSurvivalTime FactorsRecombinant ProteinsCell ProliferationSurvival AnalysisGraft SurvivalCell Line, TumorAntigens, CD31ImmunohistochemistryMice, Inbred C57BLRNA, Small InterferingVascular Cell Adhesion Molecule-1Gene Expression RegulationMicrocirculationDose-Response Relationship, DrugUp-RegulationReverse Transcriptase Polymerase Chain ReactionIntercellular Adhesion Molecule-1Mice, KnockoutE-SelectinTumor Necrosis Factor-alphaNitric Oxide Synthase Type IIINF-kappa BCell DeathNitric OxideCell Adhesion MoleculesTreatment OutcomeMicrovesselsBlood VesselsGene ExpressionCell DifferentiationMolecular Sequence DataCoculture TechniquesMembrane ProteinsModels, BiologicalAntineoplastic AgentsDown-RegulationCell HypoxiaKaplan-Meier EstimateRNA InterferenceCaspase 3Stress, MechanicalCapillary PermeabilityMice, TransgenicDisease Models, AnimalReactive Oxygen SpeciesTumor Cells, CulturedOxidative StressAntigens, CDRetrospective StudiesCulture Media, ConditionedFlow CytometryCell Communication