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  • EPCs
  • 7,8 However, since their first mention by Asahara et al, 7 the definition of circulating endothelial-regenerating EPCs that were supposed to fulfil the great expectations has been incongruent and has come under heavy debate. (ahajournals.org)
  • Conditioned media from patient EPCs were significantly reduced in their capacity to support endothelial tube formation in comparison to control EPCs. (diabetesjournals.org)
  • In addition, measurements of flow-mediated brachial-artery reactivity also revealed a significant relation between endothelial function and the number of EPCs, supporting a role for EPCs in the maintenance of endothelial integrity. (diabetesjournals.org)
  • Furthermore, we compared the capacity of patient and control EPCs to support endothelial tube formation in vitro. (diabetesjournals.org)
  • clinical
  • Written by expert researchers in the fields of endothelial biology, inflammation research and clinical science, it serves as a useful reference for academic and industrial researchers, clinicians, and trainees in the medical profession. (springer.com)
  • 2 Alteration in endothelial function precedes the development of morphological atherosclerotic changes and can also contribute to lesion development and later clinical complications. (ahajournals.org)
  • The present review summarizes current understanding of endothelial biology in health and disease, the strengths and weaknesses of current testing strategies, and their potential applications in clinical research and patient care. (ahajournals.org)
  • novel
  • The better molecular and mechanistic understanding of the complexity of endothelial cell function consequently holds great promise to lead to the development of novel therapies. (dkfz.de)
  • cardiovascular
  • OBJECTIVE To determine the effects of daily walnut consumption on endothelial function, cardiovascular biomarkers, and anthropometric measures in type 2 diabetic individuals. (diabetesjournals.org)
  • Subjects underwent endothelial function testing (measured as flow-mediated dilatation [FMD]) and assessment of cardiovascular biomarkers before and after each 8-week treatment phase. (diabetesjournals.org)
  • Therefore, this study was performed to investigate the effects of a walnut-enriched diet on endothelial function and other cardiovascular risk factors in type 2 diabetic individuals. (diabetesjournals.org)
  • Hence, detailed understanding of the underlying mechanisms involved in endothelial cell restoration are of fundamental interest for preventional and therapeutic concepts in cardiovascular disease. (ahajournals.org)
  • fundamental
  • Furthermore, a negative correlation between percent flow mediated dilation and baseline artery size is recognised as a fundamental scaling problem, leading to biased estimates of endothelial function. (wikipedia.org)