EndosomesLysosomesEndocytosisrab5 GTP-Binding Proteinsrab GTP-Binding ProteinsProtein TransportLysosome-Associated Membrane GlycoproteinsVesicular Transport Proteinstrans-Golgi NetworkOrganellesPhagosomesGolgi Apparatusrab4 GTP-Binding ProteinsCell CompartmentationCathepsin DReceptor, IGF Type 2VacuolesBiological TransportTransferrinCell MembraneMultivesicular BodiesClathrinEndosomal Sorting Complexes Required for TransportAcid PhosphataseCell LineIntracellular MembranesReceptors, TransferrinTransport VesiclesMembrane FusionMicroscopy, ElectronLysosomal-Associated Membrane Protein 2Microscopy, FluorescenceHeLa CellsAutophagySubcellular FractionsCell FractionationHydrogen-Ion ConcentrationMembrane ProteinsHorseradish PeroxidaseSorting NexinsMicroscopy, ConfocalAndrostenesClathrin-Coated VesiclesCricetinaeMicroscopy, ImmunoelectronBrefeldin AAdaptor Protein Complex 1AsialoglycoproteinsMacrolidesCathepsinsOrganoidsChloroquineMonoglyceridesQa-SNARE ProteinsCells, CulturedMannosephosphatesGreen Fluorescent ProteinsAdaptor Protein Complex 3Carrier ProteinsAntigens, CD63Recombinant Fusion ProteinsCathepsin Bbeta-N-AcetylhexosaminidasesADP-Ribosylation FactorsMolecular Sequence DataProtein BindingAmino Acid SequenceChediak-Higashi SyndromeAmmonium ChlorideModels, BiologicalExocytosisCoated Pits, Cell-MembraneCHO CellsLiverCytoplasmic VesiclesMutationMembrane GlycoproteinsAdaptor Proteins, Vesicular TransportProtein Structure, TertiaryR-SNARE ProteinsMucolipidosesVacuolar Proton-Translocating ATPasesAdaptor Protein Complex gamma SubunitsCytoplasmKineticsHydrolasesGlucuronidaseTransfectionCercopithecus aethiopsCOS CellsMacrophagesPhosphatidylinositol PhosphatesFluorescent Antibody TechniqueLysosomal Storage DiseasesMicrotubulesNiemann-Pick DiseasesCytosolFibroblastsEndoplasmic ReticulumMelanosomes