SquamousTumorsUterusEpithelialCommon gynecologic cancerBenignMalignanciesPelvic SurgeryIncidenceHyperplasiaCervical CarcinomaLung carcinomaBiopsyRecurrent vulvarEndometrioidMerkelMelanomaCervixLymphomaAdrenocortical CarcinomaVulvaBreast cancerClinicalLesionsMetastasisUncommonTumorHereditarySarcomaPrognosticTeratomaOncologistAdnexalNeuroendocrineCancersMesotheliomaTransformationAdrenalMenopausePapillary
Squamous8
- Squamous cell carcinoma (SCC) in various morphological forms needs to be separated from other epithelial tumors for treatment modality selection. (cytojournal.com)
- El Homsi M, Golia Pernicka JS, Lall C, Nougaret S, Paspulati RM, Pickhardt PJ, Sheedy SP, Petkovska I. Beyond squamous cell carcinoma: MRI appearance of uncommon anal neoplasms and mimickers. (moffitt.org)
- The two most common types of nonmelanoma skin cancer are basal cell carcinoma and squamous cell carcinoma. (moffitt.org)
- Each year, approximately 1.8 million cases of squamous cell carcinoma are diagnosed. (moffitt.org)
- Like basal cell carcinoma, squamous cell carcinoma usually appears on areas of the body that have been exposed to the sun. (moffitt.org)
- However, squamous cell carcinoma can also develop on the lips, mucous membranes (like the skin that lines the mouth or nose) and parts of the body where patients have experienced chronic inflammatory skin conditions. (moffitt.org)
- Although squamous cell carcinoma is more likely than basal carcinoma to spread or metastasize to distant areas of the body, it's still relatively rare for it to do so. (moffitt.org)
- Although basal cell carcinoma and squamous cell carcinoma make up the large majority of nonmelanoma skin cancer cases, there are various other rare forms of this malignancy that together comprise a small percentage of the total number of diagnoses. (moffitt.org)
Tumors11
- Although this most common gynecologic cancer carries the best prognosis, it is important to differentiate between the classic endometrioid tumors that tend to be estrogen dependent and well differentiated, from other less common high-risk uterine malignancies, such as uterine papillary serous carcinomas (UPSCs), clear cell carcinomas, mixed mullerian tumors (MMTs), or sarcomas, which appear to have a different biology. (medmuv.com)
- Mutation of the transforming growth factor (TGF) beta receptor type II gene is common in RER+ colon and gastric cancers, but uncommon in RER+ endometrial cancers even those arising in HNPCC kindreds, suggesting that the genesis of RER+ tumors even within the same familial cancer syndrome is not the same. (medmuv.com)
- Although inactivation of both alleles of either hMSH2 or MLH1 (DNA mismatch repair genes) appears to underlie microsatellite instability in tumors of HNPCC kindreds, similar to the findings in sporadic colon cancers, sporadic endometrial cancers were not associated with mutations of any of the four known human mismatch repair genes. (medmuv.com)
- Notable was the almost complete absence of Ki-ras mutations in an aggressive form of endometrial cancer, UPSC, when compared to the usual endometrioid tumors. (medmuv.com)
- Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
- Most often, these tumors are benign, although it is possible for them to be malignant and to spread or metastasize. (moffitt.org)
- Hematologic Neoplasia A unique association between mediastinal nonseminomatous germ cell tumors and a variety of hematologic neoplasms is now well described. (health.am)
- All hematologic neoplasms developed in the 287 patients with mediastinal nonseminomatous germ cell tumors, for a 2% incidence in this group. (health.am)
- Foci of malignant lymphoblasts have been recognized histologically in several mediastinal germ cell tumors. (health.am)
- However, the specific association of leukemias and other hematologic neoplasms with mediastinal nonseminomatous germ cell tumors, rather than with all germ cell tumors, remains unexplained. (health.am)
- Adrenocortical tumors encompass a spectrum of diseases with often seamless transition from benign (adenoma) to malignant (carcinoma) behavior. (oncolink.org)
Uterus1
- Generally, when estrogen is prescribed for a postmenopausal woman with a uterus, a progestin should also be considered to reduce the risk of endometrial cancer. (pillintrip.com)
Epithelial3
- Most of the cervical epithelial neoplasms and their precursors occur at the squamocolumnar junction or within the transformation zone. (cytojournal.com)
- Expression of cyclooxygenase-2 and inducible nitric oxide synthase in ovarian surface epithelial carcinomas: is there any correlation with angiogenesis or clinicopathologic parameters? (bmj.com)
- Berstein L, Gurney JG: Carcinomas and other malignant epithelial neoplasms. (oncolink.org)
Common gynecologic cancer1
- In the United States, ovarian cancer is the second most common gynecologic cancer (affecting approximately 1/70 women). (merckmanuals.com)
Benign5
- GATA3 Is a Sensitive and Specific Marker of Benign and Malignant Mesonephric Lesions in the Lower Female Genital Tract. (harvard.edu)
- A group of disorders having a benign course but exhibiting clinical and histological features suggestive of malignant lymphoma. (lookformedical.com)
- Pseudolymphoma is characterized by a benign infiltration of lymphoid cells or histiocytes which microscopically resembles a malignant lymphoma. (lookformedical.com)
- Mature teratomas generally are benign, with 0.17-2% of mature cystic teratomas becoming malignant. (mdwiki.org)
- The pathogenesis of leiomyoma is characterized by benign smooth muscle neoplasm . (wikidoc.org)
Malignancies2
- Ovarian cancer, uterine cervical cancer, endometrial cancer, and trophoblastic neoplasms are gynecologic malignancies for which tumor markers are in clinical use. (medscape.com)
- The pathological features of the common carcinomas are detailed and non-carcinomatous malignancies are also summarised. (nshealth.ca)
Pelvic Surgery1
- Computerized Tomography Adiposity Morphometrics: A Novel Approach to Predict Pulmonary Intolerance in Endometrial Cancer Patients Undergoing Robotic Pelvic Surgery (RPS). (moffitt.org)
Incidence2
- The replication error (RER+) phenotype is characteristic of cancers arising in HNPCC kindreds (a familial cancer syndrome with a high incidence of colon, endometrial, gastric, and a lower incidence of ovarian and pancreatic cancers), and is also found in approximately 20% of sporadic endometrial cancers. (medmuv.com)
- Authors Keywords: FIGO 2023 endometrial cancer staging Abstract Endometrial cancer incidence is rapidly rising global. (cn1699.cn)
Hyperplasia3
- Chromosome 17p is frequently involved, which contains the p53 gene known to confer a poor prognosis in endometrial cancers when mutated or deleted, and which plays an important role in the transition to carcinoma from atypical hyperplasia. (medmuv.com)
- Endometrial hyperplasia is classified by its cytology and glandular tissue. (lookformedical.com)
- There are simple, complex (adenomatous without atypia), and atypical hyperplasia representing also the ascending risk of becoming malignant. (lookformedical.com)
Cervical Carcinoma1
- Cervical Carcinoma -- 26. (nshealth.ca)
Lung carcinoma1
- Lung Carcinoma -- 18. (nshealth.ca)
Biopsy5
- Experts in endometrial cancer suggest there should be a change in the standard of care, after the largest study to date found that sentinel lymph node biopsy is as accurate for identifying metastasis as complete pelvic lymphadenectomy, which is more invasive and is the current gold standard. (medscape.com)
- The findings come from the FIRES study (Fluorescence Imaging for Robotic and Endometrial Sentinal Lymph Node Biopsy), which was published online on January 31 in Lancet Oncology . (medscape.com)
- The false negative rate was 3%, similar to that for cases of breast cancer, melanoma, and vulvar cancer, for which sentinel-lymph node biopsy has become the standard of care. (medscape.com)
- I think sentinel lymph node biopsy can replace the traditional lymphadenectomy technique and should become the standard of care in endometrial cancer. (medscape.com)
- Currently, the National Comprehensive Cancer Network endorses sentinel lymph node biopsy as an acceptable standard of care for surgical staging of endometrial cancer in select patients. (medscape.com)
Recurrent vulvar1
- To our knowledge this is the first reported case of an isolated vesicocutaneous fistula related to previous radiation therapy for recurrent vulvar cancer. (annals.edu.sg)
Endometrioid1
- Kirsten (Ki)-ras activating point mutations in codons 12 and 13 have been implicated in the development of atypical endometrial hyperplasias and endometrioid carcinomas in Japanese women, as well as in colon cancers. (medmuv.com)
Merkel1
- Merkel cell carcinoma develops in the hormone-producing cells of the skin and hair follicles. (moffitt.org)
Melanoma1
- Malignant Melanoma -- Part V. Breast Cancer -- 22. (nshealth.ca)
Cervix1
- Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)
Lymphoma2
- Malignant blast cells (i.e. diffuse large B-cell lymphoma) are fast-growing and result in aggressive disease, whereas malignant mature lymphocytes (i.e. follicular lymphoma) behave indolently. (oncolink.org)
- Nodal Malignant Lymphoma (With Comments on Extranodal Malignant Lymphoma and Metastatic Cancer) -- Part IX. (nshealth.ca)
Adrenocortical Carcinoma2
- Systemic treatment of adrenocortical carcinoma in children: data from the German GPOH-MET 97 trial. (oncolink.org)
- Factors associated with survival in pediatric adrenocortical carcinoma: An analysis of the National Cancer Data Base (NCDB). (oncolink.org)
Vulva2
- Carcinoma of the vulva is an uncommon malignancy, but one that is amenable to early diagnosis if symptoms and signs are appropriately investigated. (annals.edu.sg)
- Keywords: carcinoma of vulva, laparoscopic minimally inv. (cn1699.cn)
Breast cancer1
- CHICAGO - The application of topical liquid lidocaine to the vulvar vestibule allows for comfortable intercourse in breast cancer survivors with severe menopausal dyspareunia, new research shows. (medscape.com)
Clinical1
- No tumor markers with high sensitivity and high specificity for endometrial cancer are known at present, although CA-125 is often used in clinical practice. (medscape.com)
Lesions1
- Menometrorrhagia, which involves both excessive and irregular bleeding, should be distinguished from menorrhagia, and usually involves anovulatory cycles or genital lesions such as endometrial or cervical cancer. (mhmedical.com)
Metastasis1
- The FIRES trial was conducted in women with early endometrial cancer who were without evidence of metastasis on physical and radiologic examination. (medscape.com)
Uncommon1
- Urogenital fistulas are a known but uncommon complication of gynaecological surgery, especially those involving a malignant process. (annals.edu.sg)
Tumor4
- These data strongly suggest that some gene on chromosome 18, is a tumor suppressor gene in endometrial cancers. (medmuv.com)
- Recent evidence indicates that the hematologic neoplasms in this setting are not treatment related, but rather arise from clones of malignant lymphoblasts or myeloblasts contained within the mediastinal germ cell tumor. (health.am)
- More importantly, several patients have had an identical chromosomal abnormality (an isochromosome of the short arm of chromosome 12) in the neoplastic cells from the mediastinal germ cell tumor and the hematologic neoplasm, providing strong evidence for a common origin. (health.am)
- Malignant pleural mesothelioma is a malignant or cancerous tumor of the pleura, the mesothelium that surrounds the lungs. (bcm.edu)
Hereditary1
- thus the hereditary form of endometrial cancer alone does not appear to portend a worse prognosis than the sporadic form. (medmuv.com)
Sarcoma1
- Like other forms of soft-tissue sarcoma, cancerous (malignant) skin sarcomas are often treated by surgically excising them. (moffitt.org)
Prognostic2
- When multivariate analysis was used to determine if HER-2/neu was an independent prognostic factor in endometrial cancers taking into account other molecular features such as DNA ploidy, epidermal growth factor receptor, or p53 status, HER-2/neu status failed to achieve significance. (medmuv.com)
- Prognostic factors in ovarian carcinoma stage III patients. (bmj.com)
Teratoma1
- Immature teratoma is the malignant counterpart of the mature teratoma and contains immature tissues which typically show primitive or embryonal neuroectodermal histopathology. (mdwiki.org)
Oncologist1
- Everybody agrees that these women are in pain and aren't being well served by the current medical community," said Caela Miller, MD, assistant professor and gynecologic oncologist at the San Antonio Military Medical Center. (medscape.com)
Adnexal1
- The complex and often confusing history, histology and histogenesis of mesonephric, STK11 adnexal tumour and mesonephric-like neoplasms of the upper female genital tract (including broad ligament). (harvard.edu)
Neuroendocrine1
- Segaran N, Devine C , Wang M, Ganeshan D . Current update on imaging for pancreatic neuroendocrine neoplasms. (viictr.org)
Cancers7
- Among sporadic endometrial cancers, when present, the microsatellite instability is confined to the malignant cells, and is not seen in the adjacent normal epithelium. (medmuv.com)
- Unlike most other cancers studied so far, endometrial cancer is not characterized by a small number of loci that are involved by loss of heterozygosity. (medmuv.com)
- In endometrial cancers, most chromosomes contain regions of sustained allelic loss. (medmuv.com)
- Other frequently involved regions include 10q, 3p, and 18q, with no significant differences found in the chromosomal regions involved in endometrial from cervical cancers. (medmuv.com)
- While no mutations were found in the exons of the DCC gene in endometrial cancers, chromosome 18 was found to be capable of suppressing tumorigenicity of endometrial cancer cells in nude mice by the procedure of microcell fusion, with DCC expression elevated in most of the suppressed hybrids. (medmuv.com)
- Recent studies of endometrial cancers arising in US women, however, show the prevalence of such mutations to be significantly lower (11% versus 31%) than in Japan . (medmuv.com)
- Overexpression of HER-2/neu has been associated with advanced stage, deep myometrial invasion, and poor survival in endometrial cancers in several studies. (medmuv.com)
Mesothelioma2
- The Mesothelioma Treatment Center located at the Baylor Medicine Lung Institute is recognized worldwide, as a leading-edge center for the diagnosis, treatment, and research of malignant mesothelioma. (bcm.edu)
- Malignant mesothelioma is a type of cancer that affects the cells of the mesothelium. (bcm.edu)
Transformation1
- Malignant transformation is usually the result of chromosomal translocations that activate proto-oncogenes or create a chimeric fusion protein. (oncolink.org)
Adrenal2
- Wooten MD, King DK: Adrenal cortical carcinoma. (oncolink.org)
- Wieneke JA, Thompson LD, Heffess CS: Adrenal cortical neoplasms in the pediatric population: a clinicopathologic and immunophenotypic analysis of 83 patients. (oncolink.org)
Menopause3
- Start therapy with DOTTI 0.0375 mg/day applied to the skin twice weekly for the treatment of moderate to severe vasomotor symptoms due to menopause or moderate to severe symptoms of vulvar and vaginal atrophy symptoms due to menopause. (nih.gov)
- When prescribing solely for the treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to menopause, topical vaginal products should be considered. (pillintrip.com)
- Treatment of moderate to severe vasomotor symptoms due to menopause ) Treatment of moderate to severe symptoms of vulvar and vaginal atrophy due to Limitation of Use: When prescribing solely for the treatment of moderate to severe Inducers and/or inhibitors of CYP3A4 may affect estrogen drug metabolism. (gotomydoctor.com)
Papillary1
- Long-term survival after paclitaxel plus platinum-based combination chemotherapy for extraovarian peritoneal serous papillary carcinoma: is it different from that for ovarian serous papillary cancer? (bmj.com)