If endolymphatic hydrops is attributable to a given disease process-that is, if it is Ménière syndrome rather than Ménière disease-the first-line management is diagnosis and treatment of the primary disease (eg, syphilis, thyroid disease). (medscape.com)
It is also not clear whether endolymphatic hydrops is the cause or the result of Meniere's disease, since there are known cases of individuals with endolymphatic hydrops who otherwise have no symptoms of Meniere's disease. (medifocus.com)
The aim of the present study was to investigate the pathological features of vestibular aqueduct (VA) related high jugular bulb (HJB) and explore the possible cause-consequence relation between HJB and endolymphatic hydrops (EH), and the potential specific radiological signs for screening causative HJB in Meniere's disease (MD). (researchsquare.com)
Endolymphatic hydrops (EH) is the pathological substrate of Meniere's disease (MD), which may be caused by deficient absorption in the sac or obstruction of the endolymphatic duct (1-4). (researchsquare.com)
High jugular bulb (HJB), one of the most common anatomical variant in temporal bone, has been reported to be more common in MD, and it has been suggested to put pressure on the endolymphatic sac (ES) and distal vestibular aqueduct (VA), which contains the endolymphatic duct and the infratemporal endolymphatic sac, resulting in endolymphatic hydrops and Meniere-like symptoms (5,6). (researchsquare.com)
Tumors11
Neoplasms of the endolymphatic sac are very rare tumors. (wikipedia.org)
Objective To review the cumulative experience of surgical management of endolymphatic sac tumors (ELSTs) in the literature. (nih.gov)
Endolymphatic sac tumors are rare tumors that can result in the destruction of the ear and involvement of close by neurological structures. (newyorkear.com)
Many Endolymphatic sac tumors are benign (non-cancerous), but can show up on MRI or CAT scans and appear like acoustic neuromas (vestibular schwannomas) or meningiomas. (newyorkear.com)
1. Evaluation and management of endolymphatic sac and duct tumors. (nih.gov)
20. Endolymphatic sac tumors: histopathologic confirmation, clinical characterization, and implication in von Hippel-Lindau disease. (nih.gov)
Endolymphatic sac tumors (ELST) are also been found (up to 10%) and may cause hearing loss. (orpha.net)
Imaging studies can be used to detect CNS tumors, pheochromocytoma/paraganglioma, endolymphatic sac tumors, renal tumors, and renal and pancreatic cysts. (orpha.net)
Von Hippel-Lindau syndrome is an inherited disorder characterized by the formation of tumors and fluid-filled sacs (cysts) in many different parts of the body. (nih.gov)
About 10 percent of people with von Hippel-Lindau syndrome develop endolymphatic sac tumors, which are noncancerous tumors in the inner ear . (nih.gov)
Tumor7
2. Endolymphatic sac tumor located around semicircular canals. (nih.gov)
8. [Papillary tumor of the endolymphatic sac]. (nih.gov)
11. Endolymphatic sac tumor: unique features of two cases and review of the literature. (nih.gov)
15. Gamma knife treatment of an endolymphatic sac tumor: unique features of a case and review of the literature. (nih.gov)
16. Endolymphatic Sac Tumor as a Ménière-Like Vertiginous Syndrome: A Case Report. (nih.gov)
Surgical management of endolymphatic sac tumor: classification, outcomes and strategy. (bvsalud.org)
Vestibular aqueduct3
this duct is joined by the utriculosaccular duct, and then passes along the vestibular aqueduct and ends in a blind pouch, the endolymphatic sac, on the posterior surface of the petrous portion of the temporal bone, where it is in contact with the dura mater. (wikipedia.org)
100:148-156 Fukuzawa K, Sakagami M, Matsunaga T, Fujita H. Endocytotic activity of the free floating cells and epithelial cells in the endolymphatic sac: an electron microscopic study. (wikipedia.org)
SLC26A4 encodes a transmembrane anion exchanger, pendrin, which is expressed in a subset of nonsensory epithelial cells in the endolymphatic sac (ES). (nih.gov)
Cochlear2
9. MR imaging of the cochlear modiolus: area measurement in healthy subjects and in patients with a large endolymphatic duct and sac. (nih.gov)
The pathophysiological findings of Ménière disease are associated with an accumulation of endolymph in the cochlear duct, which occurs at the expense of the perilymphatic space, and inadequate absorption of the endolymph by the endolymphatic sac [ 2 , 4 ]. (e-jyms.org)
Endolymph2
Inside their walls (bony labyrinth) are thin, pliable tubes and sacs (membranous labyrinth) filled with endolymph. (nih.gov)
In mammals, disruptions to endolymph homeostasis can result in either collapse or distension of the endolymphatic compartment in the cochlea, with concomitant hearing loss. (biologists.com)
Tumours3
Non-cancerous tumours can form in the endolymphatic duct of the inner ear, which regulates the balance of an individual. (nccs.com.sg)
These tumours are called endolymphatic sac tumours , which can cause problems such as hearing loss or deafness. (nccs.com.sg)
7. Advanced techniques in magnetic resonance imaging in the evaluation of the large endolymphatic duct and sac syndrome. (nih.gov)
Fluid4
It is thought that otosclerotic formations may cause malformation in the endolymphatic sac or may change the chemical properties of the perilymphatic and endolymphatic fluid. (medifocus.com)
Fluid in the ear is held in a pouch-like structure called the endolymphatic sac. (merckmanuals.com)
The zebrafish little ears ( lte )mutant shows a collapse of the otic vesicle in the larva, apparently owing to a loss of endolymphatic fluid in the ear, together with an over-inflation of the swim bladder. (biologists.com)
After all the whole concept of an endolymphatic shunt is 'drain' the excess fluid away. (menieres-help.com)
Decompression2
Endolymphatic sac (ELS) decompression can be performed for patients with Meniere's disease who have failed conservative treatment such as dietary changes and medical therapy. (jomi.com)
Decompression of the sac can be accomplished by removing overlying bone, incising the dura, or stenting the dura open. (jomi.com)
Inner ear1
Mutations of the SLC26A4 gene are a common cause of hearing loss associated with enlargement of the endolymphatic sac and duct (EES) of the inner ear. (nih.gov)
Distal1
The distal projection of the endolymphatic sac in human embryos. (nih.gov)
Ultrastructural evidence of a merocrine secretion in the human endolymphatic sac. (wikipedia.org)
Posterior1
4. Risk of damage to the endolymphatic sac and duct during removal of the posterior meatal wall: an anatomic study. (nih.gov)
Development1
Although numerous radiological studies have shown smaller VA dimensions and high rate of JB abnormalities among affected individuals, suggesting that HJB is likely to interfere with VA, causing endolymphatic sac dysfunction and the development of EH (7,8). (researchsquare.com)
Human1
Human endolymphatic sac: morphologic evidence of immunologic function. (wikipedia.org)
Literature1
6. Endolymphatic sac tumour: case report and literature review. (nih.gov)
Studies1
Studies suggest that the endolymphatic duct and endolymphatic sac perform both absorptive and secretory, as well as phagocytic and immunodefensive, functions. (wikipedia.org)