The murine leukemia viruses (MLVs or MuLVs) are retroviruses named for their ability to cause cancer in murine (mouse) hosts. (wikipedia.org)
The murine leukemia viruses are group/type VI retroviruses belonging to the gammaretroviral genus of the Retroviridae family. (wikipedia.org)
Different strains of mice may have different numbers of endogenous retroviruses, and new viruses may arise as the result of recombination of endogenous sequences. (wikipedia.org)
As Type C retroviruses, replicating murine leukemia viruses produce a virion containing a spherical nucleocapsid (the viral genome in complex with viral proteins) surrounded by a lipid bilayer derived from the host cell membrane. (wikipedia.org)
Among the latter MLVs are amphotropic viruses (Gr. amphos, "both") that can infect both mouse cells and cells of other animal species. (wikipedia.org)
Exogenous and endogenous murine1
The genomes of exogenous and endogenous murine leukemia viruses have been fully sequenced. (wikipedia.org)
Recombination3
Different strains of mice may have different numbers of endogenous retroviruses, and new viruses may arise as the result of recombination of endogenous sequences. (wikipedia.org)
Serological characterization of B-tropic viruses of C57BL mice: possible origin by recombination of endogenous N-tropic and xenotropic viruses. (microbiologyresearch.org)
Spleen focus-forming viruses are generated by recombination with endogenous retroviral sequences. (nih.gov)
Strains2
We were doing work on enteric viruses in water and sewage and, at that time, I was also collecting fecal specimens from Albert Sabin's polio vaccine experiments to determine what quantities of Poliovirus were in feces, and we were using his vaccine strains in his volunteers as some indication of what you could find in raw feces. (nih.gov)
Strains of MURINE LEUKEMIA VIRUS that are replication-defective and rapidly transforming. (nih.gov)
Viral1
Different serotypes of B-tropic murine leukemia viruses and association with endogenous ecotropic viral loci. (microbiologyresearch.org)
Progeny virus4
The encoded proteins are trafficked to the plasma membrane, where they assemble into progeny virus particles. (wikipedia.org)
In this case, the progeny virus was produced in the activated form and multiple-cycle replication occurred successively. (nih.gov)
The progeny virus, however, remained inactive, and the replication was limited to a single cycle, which resulted in the limited lung lesion. (nih.gov)
The overall results suggest that some activating mechanism for the progeny virus of wild-type Sendai virus exists in the lung of mice and the principle (activator) responsible for this phenomenon has a character similar to trypsin. (nih.gov)
Erythroleukemia3
Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene. (microbiologyresearch.org)
Antibody-induced loss of Friend virus leukemia cell surface antigens occurs during progression of erythroleukemia in F1 mice. (microbiologyresearch.org)
The envelope gene plays an essential role in initiating erythroleukemia ( LEUKEMIA, ERYTHROBLASTIC, ACUTE ), manifested by splenic foci, SPLENOMEGALY , and POLYCYTHEMIA . (nih.gov)
Replication2
AB - The pneumotropism of Sendai virus in mice was studied in relation to the activation and replication of the virus in the lung. (nih.gov)
When trypsin treatment was made which cleaved F into F(1) and F(2) subunits, the virus became activated so that it could initiate replication in the bronchial epithelium of the lung. (nih.gov)
Mice4
Virus was not detected in heart tissues of adolescent ts 1 survivors, but inoculation of these mice with CVB3(m) resulted in virus concentrations similar in titers to those found in CVB3(m)-inoculated normal adolescent mice. (nih.gov)
Inactive Sendai virus grown in LLC-MK(2) cells, which possessed an uncleaved precursor glycoprotein, F, and was noninfectious to tissue culture cells, neither grew nor caused pathological changes in the lung of mice. (nih.gov)
different populations of wild mice (mus musculus domesticus) in los angeles and ventura counties were observed over their lifespan in captivity for expression of infectious murine leukemia virus (mulv) and murine mammary tumor virus (mmtv) and for the occurrence of cancer and other diseases. (liverpool.ac.uk)
only three haplotypes are found in laboratory mice: ga, gb, and gc which are represented by balb/c, akr, and dba/2 prototypes respectively. (liverpool.ac.uk)
Sendai1
PMID- 6299951 TI - Pneumotropism of Sendai virus in relation to protease-mediated activation in mouse lungs. (nih.gov)
Rous1
Transformation by subgenomic fragments of Rous sarcoma virus DNA. (wikidata.org)
Radiation2
She went back home and they said, after that, that that radiation virus turned out to be a virus. (nih.gov)
Stevenson: Before we get started on that, maybe we could go back in time and kind of pick up where Bob Huebner got started with virus cancer type investigations. (nih.gov)
Do you recall when Bob got interested in tumor viruses for the first time? (nih.gov)
They were ubiquitous and they hung around for a long time and they had qualities that some of the other DNA viruses he was aware of did not. (nih.gov)
Core1
Structural markers on core protein p30 of murine leukemia virus: functional correlation with Fv-1 tropism. (microbiologyresearch.org)
Cells1
Among the latter MLVs are amphotropic viruses (Gr. amphos, "both") that can infect both mouse cells and cells of other animal species. (wikipedia.org)
Essential1
This cleavage is essential for the Env incorporation into virus particles. (wikipedia.org)