Two recently identified exo-lytic N -acetylmuramidases (Tf_NamZ1 and Tf_NamZ2) specifically cleave the peptide-free, exogenous (nutrition source) PGN in the periplasm and release the MurNAc and disaccharide substrates for the transporters Tf_MurT and Tf_AmpG, respectively, whereas the peptide-containing, endogenous (the self-cell wall) PGN stays unattached. (karger.com)
Display our full list of chromogenic substrates . (megazyme.com)
New chromogenic substrates for the assay of alpha-amylase and (1→4)-β-D-glucanase. (megazyme.com)
DAB and 4CN are commonly used chromogenic substrates for HRP. (bio-rad.com)
However PON1 is considered as a promiscuous enzyme having also the ability to hydrolyze many other substrates such as other organophosphorous compounds, non phosphorous arylesters and also lactones, which have been considered as its primary substrates [ 19 ]. (biomedcentral.com)
Nitric oxide2
Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide (NO) synthesis inhibitor and pro-inflammatory factor. (mdpi.com)
Ozone administration also been shown to exert a protective effect against liver damage induced by carbon tetrachloride and renal ischemic-reperfusion injury by an oxidative preconditioning mechanism that stimulates antioxidant endogenous systems and modulates nitric oxide (NO) production [ 14 ]. (biomedcentral.com)
Allowing quantification1
Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. (medchemexpress.com)
Aromatic2
Indole is an aromatic, heterocyclic, organic compound with the formula C8H7N. (wikipedia.org)
Helical inclusion complexes of amylose with aromatic compounds: crystallographic evidence for new V-type allomorphs. (toulouse-biotechnology-institute.fr)
Processing techni1
The rapid processing technique of ultrasound tissue with compound environmental protection reagent can be applied to the rapid detection of tumor biopsy specimens, and different processing temperatures and durations have no significant effect on the accuracy of HE staining, IHC, fluorescence in situ hybridization and gene mutation detection. (bvsalud.org)
Inhibitor1
When these compounds were superimposed on each other and the strongest inhibitor was applied as a template, the repulsion energy of the other compounds was proportional to the logarithmic attachment-inhibiting activity. (go.jp)
Proteins2
Endogenous substances, usually proteins, that are involved in the blood coagulation process. (lookformedical.com)
These compounds generally penetrate cell membranes, act on specific target proteins in cells, regulate intracellular signaling pathways, and cause some changes in cell phenotype. (chemscene.com)
Complements1
Bioactive Compound Library Plus, with more powerful screening capability, further complements Bioactive Compound Library (HY-L001) by adding some compounds with low solubility or solution stability (Part B) and some novel, rare or exclusive compounds (Part C) to this library. (chemscene.com)
Substances1
Bioactive compounds are a general term for a class of substances that can cause certain biological effects in the body, which are the main source of small molecule drugs. (chemscene.com)
Organic1
OBJECTIVES To apply a combined metabolomic fingerprinting approach by nuclear magnetic resonance (NMR) and gas chromatography-mass spectrometry (GC-MS) to common dandelion, corn poppy and stinging nettles to obtain simultaneous identification and quantitation of the major classes of organic compounds. (academic-accelerator.com)
Targets1
MCE owns a unique collection of 17212 compounds with confirmed biological activities and clear targets. (chemscene.com)
Natural1
We identified urolithin A (UA) as a first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption. (lsd1receptor.com)
Structure-activity rel2
Screening of a collection of 450 compounds as inhibitors revealed a structure-activity relationship that mimics in part that of mammalian DPP9. (inra.fr)
In this paper, we discuss the structure-activity relationship of these phloroglucinol compounds on the basis of molecular mechanics calculations. (go.jp)
Include1
Other indolic compounds include the plant hormone auxin (indolyl-3-acetic acid, IAA), tryptophol, the anti-inflammatory drug indomethacin, and the betablocker pindolol. (wikipedia.org)
Plant1
Also prepared was [9,9′- 13 C 2 ]-5,5′-DFA, which was proved to be a good internal standard on GC-MS quantification of endogenous 5,5′-DFA from plant tissues. (go.jp)
Analysis1
This gene construct contains the entire upstream regulatory sequence of c-fos, and expression of the endogenous and fusion gene was shown by Northern analysis to correlate upon induction with the phorbol ester 12-O-tetradecanoylphorbol 13-acetate (TPA). (elsevierpure.com)
Research1
Compound libraries are useful professional tools for drug discovery and new indication research. (chemscene.com)
Substrate1
TiO2-PCA catalyzed dissolved oxygen rather than H2O2 to generate colorimetric signal by stimulating the chromogenic substrate, which made the assay greener and safer. (bvsalud.org)
Esterases2
AM esters and diacetate compounds should be dissolved in a solution that is free of serum, because serum could contain esterases that would hydrolyze the compound. (biotium.com)
This product is a mixture of three molecular species, all of which are readily hydrolyzed by endogenous esterases into a single BCECF free acid form once they are in the cells. (biotium.com)
Precursors1
Substituted indoles are structural elements of (and for some compounds, the synthetic precursors for) the tryptophan-derived tryptamine alkaloids, which includes the neurotransmitter serotonin and the hormone melatonin, as well as the naturally occurring psychedelic drugs dimethyltryptamine and psilocybin. (wikipedia.org)
Inhibitors2
Screening of a collection of 450 compounds as inhibitors revealed a structure-activity relationship that mimics in part that of mammalian DPP9. (inra.fr)
2003 Besides the propeptide-catalytic domain name interaction the activity of the cysteine cathepsins is usually strictly regulated by a variety of endogenous proteinaceous inhibitors. (clinical-research-informatics.com)
Phenolic1
Cannabis leaves contain a diverse range of antioxidants, including cannabinoids, flavonoids, and phenolic compounds, which offer significant health benefits. (mdpi.com)
20191
2019. Engineering of a chromogenic enzyme screening system based on an auxiliary indole-3-carboxylic acid monooxygenase. (bchi.lt)
Solvent2
Tetralin, a dicyclic solvent structurally related to acetyl ethyl tetramethyl tetralin, a chromogenic and neurotoxic agent, reportedly induces excretion of green urine, and causes neurological disturbances in humans. (nih.gov)
stirring until temperature reached 30 °C. In order to obtain antioxidant solutions with similar molar concentrations, 15-63 mg ABT-263 order of each carotenoid, trolox and α-tocopherol was dissolved in a PRKD3 solvent in which each compound is highly soluble (dichloromethane for carotenoids and ethanol for α-tocopherol and trolox), and added to the polymer solution. (histaminereceptor-signal.com)
Protein2
Succinimidyl esters (SE) should be dissolved in a solution that is free of amine-containing compounds like Tris, glycine, or protein, which will react with the SE functional group. (biotium.com)
A class of G protein-coupled receptors which bind histamine as their primary endogenous ligand. (histaminereceptor-signal.com)
Activity2
Background: The anti-inflammatory activity of magnolol and related compounds is currently a focus of interest. (iiarjournals.org)
The prodrugs, except compound 5, exhibited very potent activity similar to that of araC ( $ED_{50}$ about $0.12{\mu}g/mι$ ) when evaluated against another human DNA virus, cytomegarovirus. (koreascience.kr)
Term1
Fluorescent compounds should be protected from light for long term storage. (biotium.com)
Solution1
1. Pretreat sections with a methanolperoxide solution to eliminate endogenous peroxidases. (agrisera.com)
Study1
In the present study, the inhibitory effects of these compounds on cyclooxygenase (COX-2) expression and nuclear factor-kappa B (NF-κB) activation were investigated in RAW264.7 macrophage-like cells stimulated with the fimbriae of Porphyromonas gingivalis, an oral anaerobe. (iiarjournals.org)