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  • genes
  • In contrast, whereas induction of Sox17α and HNF1β by GATA4 and 5 was substantially reduced when protein synthesis was inhibited, induction by GATA6 was minimally affected, suggesting that GATA6 is a direct activator of these early endodermal genes. (biologists.org)
  • Our modeling will provide testable hypotheses for performing double knockdowns to test the predictive quality of our GRN and to reveal the importance of multifactorial control over endodermal genes. (grantome.com)
  • signals
  • Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme. (nih.gov)
  • gene
  • Together with the timing of their expression and the effects of GATA MOs in vivo, these observations identify GATA6 as the predominant GATA factor in the maintenance of endodermal gene expression by TGFβ signaling in gastrulating embryos. (biologists.org)
  • embryos
  • Because digestive tract anomalies in mouse embryos with excess Notch activity phenocopy the absence of Hh signaling, we postulated that endodermal Hh restrains mesenchymal Notch pathway activity. (nih.gov)
  • phloem
  • The endodermal expression of EPFL4 or EPFL6 and the phloem expression of ER are sufficient for proper inflorescence growth. (pnas.org)
  • protein
  • Collectively, our data show that SCL23 is a mobile protein that controls SHR movement and acts redundantly with SCR to specify endodermal fate in the root meristem. (uu.nl)
  • development
  • EGY1 is specially required for the development of full-size endodermal plastid in seedlings that are grown on sucrose-free media under light. (deepdyve.com)
  • presence
  • Presence of 4 full-size plastids per endodermal cell together with ethylene pretreatment of hypocotyls becomes sufficient to trigger vigorous gravicurvature in light-grown seedlings. (deepdyve.com)
  • Role
  • It plays a direct role in controlling the light-induced chlorophyll production, grana formation and plastid replication in endodermal cell. (deepdyve.com)
  • However, it plays an indirect role in regulation of endodermal plastid size. (deepdyve.com)
  • A model is therefore proposed to address the role of EGY1 in regulation of endodermal plastid size and number as well as the stimulatory effect of ethylene on hypocotyl gravitropism. (deepdyve.com)
  • mass
  • The degree of ethylene-dependent gravicurvature is positively correlated with the combined state of endodermal plastid mass and number. (deepdyve.com)
  • Full
  • Neither ethylene nor EGY1-regulated full-size endodermal plastid is sufficient for promotion of vigorous hypocotyl gravitropism. (deepdyve.com)
  • Report
  • Here we report that endodermal cell fate also requires the joint activity of both SCR and its closest homologue SCARECROW-LIKE23 (SCL23). (uu.nl)