Endocytosis function carrier proteins. Medical search. Frequent questions

G protein-coupled receptors (GPCRs) are, with approximately 800 members, among the most abundant membrane proteins in humans. (nih.gov)
Along their life cycle, GPCRs are accompanied by a range of specialized GPCR-interacting proteins (GIPs) to assist nascent receptors in proper folding, to target them to the appropriate subcellular compartments and to fulfill their signaling tasks. (nih.gov)
Insulin receptors are regulated by endocytosis, a process that removes receptors from the cell surface to be marked for degradation or for re-use. (bvsalud.org)
Immunohistochemistry revealed decreased expression of megalin and cubilin, two important multiligand protein receptors on the brush border of proximal tubular epithelial cells. (biomedcentral.com)
Megalin and cubilin are multiligand protein receptors expressed at the brush border membrane and involved in endocytosis in PTECs. (biomedcentral.com)
The plasma membrane can be envisioned as a central compartment in the cellular adaptation to diverse stress conditions as it shapes the interactions between cells and their environment by harboring an elaborate complement of transmembrane proteins, e.g. transporters, channels, receptors, or adhesion proteins. (cell-stress.com)
The absorption of LMW proteins occurs in the PTC through clathrin-mediated endocytosis via 2 multiligand receptors (megalin and cubilin) present in the PTC apical border. (medscape.com)
Megalin is internalized by endocytosis and delivered to vacuolar endosomes, which then sort megalin into recycling tubules and deliver it back to the plasma membrane, thus keeping an abundant number of megalin receptors at the apical surface of PTC for further endocytosis and recycling. (medscape.com)
We have recently identified a novel family of CLRs and my research is aimed at better understanding the roles and functions of these receptors and how they influence innate and adaptive immunity during fungal infection. (exeter.ac.uk)
We have previously shown that hemocyanins are internalized by APCs through receptor-mediated endocytosis with proteins that contain C-type lectin domains, such as mannose receptor (MR). However, the contribution of other innate immune receptors to the proinflammatory signaling pathway triggered by hemocyanins is unknown. (exeter.ac.uk)
However several essential AMG-925 nutrients and carrier proteins are thought to mix the BBB via receptors indicated on mind endothelial cells through a process known as receptor-mediated transcytosis (Rubin and Staddon 1999 Predescu et al. (biotech-angels.com)
Membrane receptors are specialized protein molecules attached to or integrated into the cell membrane. (rhumbarlv.com)
Receptors are generally transmembrane proteins, which bind to signaling molecules outside the cell and subsequently transmit the signal through a sequence of molecular switches to internal signaling pathways. (rhumbarlv.com)
Receptors are a special class of proteins that function by binding a specific ligand molecule. (rhumbarlv.com)
The LDL receptor and transferrin receptors are examples of receptors that function by receptor-mediated endocytosis. (rhumbarlv.com)
membrane receptors are specialized protein molecules in the membranes of cells, to which external molecules (hormones, neurotransmitters, drugs) attach, triggering changes in the function of the cell. (rhumbarlv.com)
Hundreds of different G-protein-linked receptors have been identified. (rhumbarlv.com)

This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. (wikipedia.org)

They function as carriers to the cell surface in post-golgi recycling pathways. (wikipedia.org)
These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways. (wikipedia.org)
DAVID Pathways, a functional annotation tool, helped identify a set of 11 genes from a single cluster associated with the endocytosis pathway related to insulin resistance. (bvsalud.org)
While certain aspects of stress-elicited adaptive programs such as the heat shock response or the oxidative stress response are very well studied, the contribution of other cellular pathways including endocytosis to cellular adaptation is still elusive. (cell-stress.com)
Before entering lipid synthesis pathways, different kinds of acyl-CoA transporters which acts as the major carrier of acyl-CoAs, such as fatty acid binding protein (FABP), sterol carrier protein 2 (SCP2) and acyl-CoA-binding protein (ACBP), would activate and convert fatty acids to fatty acyl-CoA esters via a reaction catalyzed by fatty acyl-CoA synthetase and transported to various metabolic locations [ 11 ]. (biomedcentral.com)
Subsequent molecular and physiological studies in human mutation carriers and animal models have allowed us to unravel novel functions of the identified genes, to delineate their cognate pathways and to discover new targets for pharmaceutical intervention. (yale.edu)
Calcium plays a critical role in several body functions such as, coagulation pathways, bone health, nerve conduction, and other functions. (dssurgery.com)
These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. (nih.gov)

Solute carrier (SLC) transporters control fluxes of nutrients and metabolites across membranes and thereby represent a critical interface between the microenvironment and cellular and subcellular metabolism. (life-science-alliance.org)
One-by-one depletion of 13 amino acids required for cell proliferation enabled gain-of-function genetic screens using a SLC-focused CRISPR/Cas9-based transcriptional activation approach to uncover transporters relieving cells from growth-limiting metabolic bottlenecks. (life-science-alliance.org)

Secretory carrier-associated membrane protein 1 is a protein that in humans is encoded by the SCAMP1 gene. (wikipedia.org)
These data highlight the importance of membrane protein recycling during development. (sdbonline.org)
Based on these S-layer proteins, supramolecular assemblies can be constructed which are envisaged for label-free detection systems, as affinity matrix, as anti-allergic immuno-therapeutics, as membrane protein-based screening devices, and as drug targeting and delivery systems. (2medicalcare.com)
Which is not a function of a membrane protein? (rhumbarlv.com)
Four types of membrane proteins are Integral Membrane Protein, Peripheral Membrane Protein, Transmembrane Protein, and Integral Monotopic Proteins. (rhumbarlv.com)

The objective of this review is to discuss how miRNAs are released by active exocytosis and to examine the physiological functions of vesicle-free miRNAs in neuroendocrine cells. (frontiersin.org)
Compare and contrast endocytosis and exocytosis. (macomb.edu)

Alternative splicing can often result in the expression of distinct protein isoforms from a single gene, with specific composition and properties. (bvsalud.org)
Several research groups have studied the physiological importance of Sgip1, and four Sgip1 protein isoforms have been described to date, while the NCBI Gene database predicts the expression of 20 splice variants from the Sgip1 gene in mice. (bvsalud.org)
tRNA and rRNA are dominant ncRNAs, miRNAs have critical functions in gene expression. (frontiersin.org)
60% of human protein-coding genes, mostly by binding to the 3′- untranslated region (3′UTR) of the target mRNAs ( 5 ) and, therefore, miRNAs affect gene expression networks of a variety of biological processes including development, apoptosis, proliferation, and metabolism ( 1 , 2 ). (frontiersin.org)
This process allows a variety of important applications, including the study of gene regulation, the analysis of the expression of proteins within eukarotic cells such as those of mammals, the production of transgenic organisms , and the methods of gene therapy. (newworldencyclopedia.org)
Therefore, the development of novel visible ultrasonic responsive nanosized drug/gene carriers is necessary. (hindawi.com)
Furthermore, as targeted delivery carriers, gene/drug-loaded nanocarriers can release their associated payload upon insonation. (hindawi.com)
Lowe syndrome is caused by an inherited mutation in the OCRL gene, mapped to chromosome Xq 26.1, which encodes the OCRL1 protein. (medscape.com)
One of our recent groundbreaking discoveries was the identification of novel loss of function mutations in a gene encoding the pancreatic exocrine elastase Cela2a in patients with diabetes, CAD and MetS traits, including obesity, hypertension, hypertriglyceridemia, NAFLD (OMIM: AOMS4). (yale.edu)
The protein is associated with microtubules , and Chatterjee and colleagues silenced the gene via short interfering RNA (siRNA) a molecular biological mechanism to study genes, targeting the CKAP5 encapsulated in lipid nanoparticles for in vivo delivery. (medicalxpress.com)
Studies suggest that mutations in the CLCN5 or OCRL gene disrupt the reabsorption function of the proximal tubules, which leads to the progressive kidney problems found in people with Dent disease. (medlineplus.gov)
In X-linked recessive inheritance, a female with one mutated copy of the gene in each cell is called a carrier. (medlineplus.gov)

Endocytosis is a fundamental process involved in trafficking of various extracellular and transmembrane molecules from the cell surface to its interior. (mdpi.com)
2007 Transferrin (Tf) receptor (TfR) a type II transmembrane protein highly indicated on mind endothelial cells (Jefferies et al. (biotech-angels.com)
Integral membrane proteins are a permanent part of a cell membrane and can either penetrate the membrane (transmembrane) or associate with one or the other side of a membrane (integral monotopic). (rhumbarlv.com)
The LDL receptor is a transmembrane protein of the plasma membrane. (rhumbarlv.com)

Membrane-enclosed structures called vesicles transport proteins and lipids across the cell. (jove.com)
Egg yolk constitutes a major source of proteins, minerals, vitamins and lipids for the developing embryo. (biomedcentral.com)
As such as proteins, lipids, glycans, nucleic acids, and isoporous ultrafiltration membrane they can apparently combination of that. (2medicalcare.com)

The plasma membrane is not only the first point of encounter for many types of environmental stress, but given the diversity of receptor proteins and their associated molecules also represents the site at which many cellular signal cascades originate. (cell-stress.com)
Act as carrier molecules for various solutes is not a function of membrane proteins. (rhumbarlv.com)

Differential expression of GIPs and rapid alterations of GPCR/GIP interaction networks are efficient means to regulate GPCR function in a tissue-specific and spatiotemporal manner to trigger appropriate cellular responses. (nih.gov)

Coated vesicles are spherical, protein-coated carriers with a 50-100 nm diameter that mediate bidirectional transport between the ER and the Golgi. (jove.com)
The distribution of proteins between the ER and Golgi complex is dynamic and is maintained by different coated vesicles. (jove.com)
The OCRL1 protein is an inositol polyphosphate 5-phosphatase primarily located in the trans- Golgi network (TGN), on endosomes, and at the endocytic clathrin coated pits. (medscape.com)
OCRL1 has been localized to the trans -Golgi network and various compartments of the endocytic pathway (traffic), where it is found in the clathrin-coated pits, clathrin-coated vesicles, variable functioning endosomes (early, signaling, recycling), and the basal body of primary cilia. (medscape.com)
Loss of Pcs impairs Rab11 localization on the trans-side of Golgi units and induces the cytoplasmic accumulation of post-Golgi vesicles bearing rhabdomere proteins, as observed in Rab11-deficiency. (sdbonline.org)
These results indicated that both TRAPPII and Pcs are required for eye development, but Pcs functions as the predominant Rab11-GEF for post-Golgi transport to photosensitive membrane rhabdomeres. (sdbonline.org)

Thus, endomembrane-modifying proteins within the endomembrane system will have an influence on the final grain quality/yield and recombinant protein production. (nature.com)
The NcACBP recombinant protein was able to specifically bind acyl-CoA esters in vitro . (biomedcentral.com)

Proteins fated to be internalized by clathrin-mediated endocytosis require an endocytic motif, where AP-2 or another adaptor protein can bind and recruit clathrin. (bvsalud.org)
Changes in the overall endocytic flux or in the endocytic regulation of select proteins conceivably can help to counteract adverse environmental conditions. (cell-stress.com)
Previous work from our group has reported the critical function of for the operation of salt-induced endocytic pathway, as well as the expansion of endomembrane compartments under saline stress conditions. (ncbs.res.in)

Moreover, endosomal sorting complex required for transport (ESCRT)-related proteins and their transcripts are most abundant at early and mid-development. (nature.com)
The GTPase Rab11 regulates endosomal protein trafficking and previous work has shown that loss of Rab11 caused intestinal inflammation and hyperplasia in mice and flies. (sdbonline.org)

Based on the type of protein coats, these vesicles can be of three types: coat protein or COP-coated vesicles, COPI and COPII, and clathrin-coated vesicles. (jove.com)
COPI and COPII vesicles are composed of similar coat protein complexes called coatomers. (jove.com)

What is the function of transport proteins embedded in the cell membrane? (cheatography.com)

The transfer of the major egg yolk proteins such as Very Low Density Lipoproteins (VLDL) containing essentially apovitellenin and apolipoprotein-B, but also vitellogenins and some other plasma proteins from the blood such as serum albumin to the interstitial fluid of the thecae is possible due to the presence of broad discontinuities in the capillary endothelium. (biomedcentral.com)
Albumin is the most abundant circulating protein in the plasma, accounting for more than half of the human plasma protein. (meditechinsights.com)
Albumin has been widely studied as a protein carrier for drug delivery. (meditechinsights.com)
Albumin has emerged as one of the most important drug carriers for therapeutically active drugs, peptides, and antibodies. (meditechinsights.com)
Considering the commercial success of products that use albumin as a drug carrier and the ongoing clinical trials as well as due to the advent of many diverse technologies for improving the pharmacokinetic profile and drug targeting potential of therapeutic and diagnostic peptides, albumin is attracting the interest of researchers and also the pharmaceutical and biotechnological companies, which in turn is driving the growth of albumin market. (meditechinsights.com)
Albumin can specifically bind to gp60 and SPARC-mediated receptor endocytosis and thus can actively increase the uptake of the nanoparticles. (meditechinsights.com)
Most thyroxine is bound to carrier proteins, such as thyroxine-binding globulin (TBG), transthyretin, and albumin in circulation, with only a tiny fraction (approximately 0.03%) present as free thyroxine (FT4)[3]. (myendoconsult.com)
T3 circulates bound to carrier proteins (mainly TBG and albumin), with a small fraction (approximately 0.3%) existing as free triiodothyronine (FT3). (myendoconsult.com)
This may be the reason for a patient with a low albumin/protein level, also having their calcium level reported as low. (dssurgery.com)
The first step in a patient who has low calcium reported, is to make sure their protein and albumin levels are normal, along with Vitamin D. (dssurgery.com)
Approximately 40% of total calcium is bound to serum proteins, and 80% to 90% of this calcium is bound to albumin. (abdominalkey.com)
An increase in serum albumin concentration of 1 g/dL increases protein-bound calcium by 0.8 mg/dL, whereas an increase of 1 g/dL of globulin increases protein-bound calcium by 0.16 mg/dL. (abdominalkey.com)

1998 has been proposed to undergo transcytosis in the BBB to allow access of iron-bound Tf by constitutive endocytosis (Fishman et al. (biotech-angels.com)

functional characterization of nat/ncs2 proteins of aspergillus brasiliensis reveals a genuine xanthine-uric acid transporter and an intrinsically misfolded polypeptide. (liverpool.ac.uk)
The characterization of this protein in vivo has shown that it widely expressed in different tissues and circulates in the blood, its levels rise after food intake in humans and stimulates insulin secretion and sensitivity and inhibits platelet aggregation. (yale.edu)

What are receptor proteins simple definition? (rhumbarlv.com)
How are receptor proteins located in the cell membrane? (rhumbarlv.com)
What are receptor proteins examples? (rhumbarlv.com)

in the filamentous fungus aspergillus nidulans, however, little is known about the molecular genetic mechanisms of vacuolar biogenesis and function. (liverpool.ac.uk)

These include 37 proteases and antiproteases, which are likely to play a role in the formation of the yolk (vitellogenesis), as regulators of protein metabolism. (biomedcentral.com)
HMOX2 is constitutively expressed to encode a 36 kDa HO-2 protein, mainly functioning to maintain the basal heme metabolism and may also play a role in inflammatory responses [ 4 ] . (encyclopedia.pub)

Multiomics Analysis of Endocytosis upon HBV Infection and Identification of SCAMP1 as a Novel Host Restriction Factor against HBV Replication. (nih.gov)

It also refers as " Extrinsic proteins " that associates with the lipid bilayer by weak electrostatic and hydrogen bond interactions. (rhumbarlv.com)

OBJECTIVES: Our goal was to discover insulin-resistance-related genes that play key roles in endocytosis which could serve as potential biological targets to enhance insulin sensitivity. (bvsalud.org)
Eleven genes part of the KEGG endocytosis pathway were identified. (bvsalud.org)

During 2010-2015 our researches were aimed at studying the interaction of diphtheria toxin (DT) with mammalian cells, as well as functions of DT receptor, the precursor of heparin-binding epidermal growth factor-like growth factor proHB-EGF. (org.ua)

SH3-containing GRB2-like protein 3-interacting protein 1 (Sgip1) is a brain-enriched protein that regulates clathrin-mediated endocytosis and interferes with the internalization of cannabinoid receptor 1. (bvsalud.org)

Fanconi syndrome, the result of proximal tubule epithelial cell (PTEC) injury leading to proximal RTA (type II RTA), hypophosphatemia, hypouricemia, aminoaciduria, glycosuria and urine loss of low molecular weight proteins, is a rare manifestation of pSS. (biomedcentral.com)
This suggested carrier was investigated by utilizing molecular simulations. (biomedcentral.com)
On the other hand, DT represents a very interesting molecular machine which allows using this protein in different bioengineering applications, such as ablation of certain cell types in transgenic mice, development of immunotoxins targeted for specific cell markers and also for delivery of certain proteins into the cytosol. (org.ua)
Membrane trafficking defects caused by mutation in OCRL may explain renal tubular defects observed in Lowe syndrome, including the inability of proximal tubular cells (PTC) to reabsorb low-molecular weight (LMW) proteins and other solutes such as phosphorus and bicarbonate from the glomerular filtrate. (medscape.com)
The low number of megalin at the PTC apical border explains the reduced endocytosis of low-molecular weight proteins that occur in Lowe syndrome. (medscape.com)
The present study unravels a new molecular system for vesicle-based axonal transport of proteins in male and female flies (Drosophila melanogaster). (sdbonline.org)

The most frequent sign of Dent disease is the presence of an abnormally large amount of proteins in the urine (tubular proteinuria). (medlineplus.gov)

Genetic material, such as sections of DNA coding for proteins , may be transfected. (newworldencyclopedia.org)

These assist with protein folding and, thereby, help to keep the cellular protein machinery functional in spite of adverse thermal conditions. (cell-stress.com)
Overall, this gain-of-function approach using human cells uncovered functional transporter-nutrient relationships and revealed that transport activity up-regulation may be sufficient to overcome environmental metabolic restrictions. (life-science-alliance.org)
Surface (S)-layer proteins and S-layer fusion proteins incorporating functional sequences, self-assemble into monomolecular lattices on solid supports and on various lipid structures. (2medicalcare.com)

This single-chain 535 amino acid long protein causes the symptoms of acute diphtheria infection. (org.ua)
The 302 amino acid (aa), 43 kDa protein contains a 17 aa signal sequence, an N-terminal acidic region that binds calcium, a follistatin domain containing Kazal-like sequences, and a C-terminal extracellular calcium (EC) binding domain with two EF-hand motifs (1‑5). (rndsystems.com)
We have identified a cytosolic acyl-CoA binding protein, with highly conserved amino acid residues and a typical acyl-CoA binding domain in N. caninum . (biomedcentral.com)

DT binding to proHB-EGF on a plasma membrane triggers internalization of DT-proHB-EGF complex through the clathrin-dependent endocytosis. (org.ua)

Each follicle is composed of a rim of simple cuboidal epithelial cells encircling a mass of colloidal storage protein named thyroglobulin. (myendoconsult.com)
Controlling or major regulatory hormones include PTH, calcitonin, and vitamin D. In the kidney, vitamin D and PTH stimulate the activity of the epithelial calcium channel and the calcium-binding protein (ie, calbindin) to increase calcium absorption. (dssurgery.com)

BACKGROUND: Insulin resistance is the decreased effectiveness of insulin receptor function during signaling of glucose uptake. (bvsalud.org)

CHCHD2 (mutations of which cause an autosomal dominant form of PD) encodes a mitochondrial intermembrane protein 1 . (nature.com)

Specific coat proteins cover their cytosolic surface. (jove.com)
in fungi and plants, vacuoles function as a storage and sequestration vessel for a wide variety of ions and are responsible for cytosolic ion homeostasis and responses to ionic shock. (liverpool.ac.uk)

These results raise the question of the biological significance of egg yolk proteases and antiproteases, and more generally of all minor proteins that have been identified in egg yolk. (biomedcentral.com)

This review focuses on the mechanisms by which vesicle-free miRNAs are secreted from neuroendocrine cells and will discuss potential functions of vesicle-free miRNAs and how vesicle-free miRNAs regulate cell-to-cell communication. (frontiersin.org)
The most rapid means to alter the cell surface proteome in response to stress is by alterations in endocytosis. (cell-stress.com)
These cell surface proteins impinge on the vast majority of all cellular functions by mediating nutrient uptake, preserving ion homeostasis and initiating complex signaling cascades in response to extracellular cues. (cell-stress.com)
This leads to an almost complete arrest of protein synthesis in the cell and its death. (org.ua)
HOs are expressed in a variety of cell types, rendering their broad contribution to cell functions. (encyclopedia.pub)
2011 We also lately reported that affinity and effector function determine the basic safety profile of TfR healing antibodies in vivo hence further helping low-affinity strategies and the necessity to better understand the root cell biology (Sofa et al. (biotech-angels.com)
Cell mitosis is an attractive target to effectively treat a variety of cancer forms, where microtubule-associated proteins (MAPs) assist cells to maintain the stability of cell dynamics. (medicalxpress.com)
What are proteins in a cell membrane? (rhumbarlv.com)

Protein synthesis and lipogenesis are highly stimulated in the liver at sexual maturity in hens (15 to 20 fold) to support the incorporation of 0.75 kg proteins and 1.5 kg of triglycerides into the yolk over a year of commercial production. (biomedcentral.com)
Lipid synthesis requires bulk carbon skeleton acyl-CoAs, the transport of which depends on the acyl-CoA binding protein (ACBP). (biomedcentral.com)

To test the idea that loss of Rab11 may promote cancer progression, archival human patient tissues were analyzed and 51 out of 70 colon cancer tissues had lower Rab11 protein staining. (sdbonline.org)

For a more thorough review of the role of phosphatidylinositol and the cellular and physiological functions of OCRL1 please refer to the following 2 reviews: (1) McCrea HJ, De Camilli P. Mutations in phosphoinositide metabolizing enzymes and human disease. (medscape.com)
[ 2 ] and (2) Mehta ZB, Pietka G, Lowe M. The cellular and physiological functions of the Lowe syndrome protein OCRL1. (medscape.com)

However, evaluating the precise effects of dR on neuronal functions in cultured cells under physiological conditions over a long period of time is difficult. (nature.com)
It is synthesized by hepatocytes and rapidly excreted into the bloodstream, where it carries out several functions including the modulation of plasma oncotic pressure, solubilizing long chain fatty acids, delivery of nutrients to cells, balancing plasma pH, and the transport of endogenous and exogenous ligands such as drugs. (meditechinsights.com)
Mollusk hemocyanins have biomedical uses as carriers/adjuvants and nonspecific immunostimulants with beneficial clinical outcomes by triggering the production of proinflammatory cytokines in antigen-presenting cells (APCs) and driving immune responses toward type 1 T helper (Th1) polarization. (exeter.ac.uk)
Iodide ions are then transported to the apical membrane of the thyroid follicular cells by the action of pendrin, an anion exchanger protein. (myendoconsult.com)
List the typical parts of eukaryotic cells and their functions. (macomb.edu)
One such protein is the cytoskeleton-associated protein 5 (CKAP5), widely expressed in a variety of cells to regulate the dynamics of microtubules in human cells. (medicalxpress.com)

c TEL bound within the NPET with the surrounding nucleotides of the 25S rRNA (gray) and His133 residue of uL22 protein (purple). (ciisb.org)
Laboratory results may not explicitly label it as such, however, it measures the calcium that is bound to protein . (dssurgery.com)
What does membrane bound protein mean? (rhumbarlv.com)
Total serum calcium is divisible into protein-bound and ultrafiltrable (diffusible) calcium ( Fig. 6-1 ). (abdominalkey.com)
Variations in serum protein alter proportionately the concentration of the protein-bound and total serum calcium. (abdominalkey.com)
Hyponatremia increases, whereas hypernatremia decreases protein-bound calcium. (abdominalkey.com)
Changes in pH also affect protein-bound calcium, and an increase or decrease of 0.1 pH increases or decreases protein-bound calcium by 0.12 mg/dL. (abdominalkey.com)

However, when adjusted for the protein deficiency the corrected calcium comes into normal range. (dssurgery.com)

ESRD is a life-threatening failure of kidney function that occurs when the kidneys are no longer able to filter fluids and waste products from the body effectively. (medlineplus.gov)

Exosomes, microvesicles, and apoptotic bodies are considered as carriers of extracellular miRNAs ( 21 ). (frontiersin.org)
More than 90% of extracellular miRNAs are vesicle-free, but form a complex with proteins such as Agonaute2 (AGO2) ( 22 , 23 ). (frontiersin.org)

Based on proteome annotation and a homology search, 94 proteins associated with the endomembrane system were identified that exhibited significant changes in abundance during grain development. (nature.com)

Anatomy24

Organisms14

Chemicals and Drugs144

Analytical, Diagnostic and Therapeutic Techniques and Equipment21

Phenomena and Processes49

Technology, Industry, Agriculture2

Information Science3

Health Care2

Receptors17

Secretory carrier membrane1

Pathways8

Transporters2

Membrane protein5

Exocytosis2

Gene12

Transmembrane4

Lipids3

Molecules2

GPCR1

Golgi6

Recombinant Protein2

Endocytic3

Endosomal2

Vesicles2

Embedded in the cell membrane1

Albumin12

Constitutive1

Characterization2

Receptor proteins3

Vacuolar1

Metabolism2

SCAMP11

Lipid bilayer1

Genes2

Mammalian1

Regulates1

Molecular6

Proteinuria1

Genetic1

Functional3

Amino acid3

Plasma membrane1

Epithelial2

Insulin1

Encodes1

Cytosolic2

Proteases1

Cell8

Synthesis2

Tissues1

Physiological functions2

Cells6

Bound7

Deficiency1

Occurs1

Extracellular2

Proteome1