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  • pathway
  • In this review, we propose that caveolae and rafts are internalized via a common pathway, caveolae/raft-dependent endocytosis, defined by its clathrin independence, dynamin dependence, and sensitivity to cholesterol depletion. (rupress.org)
  • Clathrin-independent endocytosis includes the constitutive pinocytotic pathway as well as endocytosis mediated by caveolae and glycolipid rafts. (rupress.org)
  • In this review, we argue that caveolae and rafts mediate a common endocytic pathway, caveolae/raft-dependent endocytosis, defined by its clathrin independence, dynamin dependence, sensitivity to cholesterol depletion, and the morphology and lipid composition of the vesicular intermediate. (rupress.org)
  • The role of clathrin-dependent pathway in CFTR endocytosis was evaluated in cells exposed to hypertonic medium, potassium depletion or intracellular acid load. (mcmaster.ca)
  • Actin
  • E-cadherin endocytosis is blocked by IQGAP1 unless actin filaments are disrupted by Lat-A. E-cadherin interacts with other E-cadherin molecules on neighboring cells to form cell-cell adhesions. (rupress.org)
  • Phagocytosis
  • We find a whole range of different engulfment behaviors with some ellipsoids engulfing faster than spheres, and that phagocytosis is able to engulf a greater range of target shapes than other types of endocytosis. (pnas.org)
  • signal transduction
  • Roles for endocytosis in immune responses, transcellular transport, signal transduction, neural function and avariety of pathological conditions are now well established. (indigo.ca)
  • neurons
  • In this study, we have used our recently developed mouse model for AGU and analyzed processing, intracellular localization, and endocytosis of recombinant AGA in telencephalic AGU mouse neurons in vitro . (jneurosci.org)
  • morphology
  • Its cytoskeleton, the morphology of its hydrogenosomes, and endocytosis phenomena have been observed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). (scielo.cl)
  • cell
  • Because the activation of Rac strengthens cell-cell interactions, the authors plan to determine whether down-regulation of Rac at adhesion sites-and thus reactivation of endocytosis-is essential for HGF-induced cell dissociation. (rupress.org)
  • Occurrence of such ability in a bacterium is consistent with autogenous evolution of endocytosis and the endomembrane system in an ancestral noneukaryote cell. (pnas.org)
  • A major unsolved problem in biology is how the many unique characteristics of the eukaryote cell evolved, including endomembranes and their dynamic features, such as endocytosis ( 1 ). (pnas.org)
  • Conversely, clathrin-mediated endocytosis is a more passive process, with targets appearing to sink into the cell ( 10 ). (pnas.org)