• That realization led, in the early 1990s, to the introduction of the term endocrine disruptor . (britannica.com)
  • The clearest example of an endocrine disruptor in humans is diethylstilbestrol (DES), a synthetic oestrogen prescribed in the 1950s and 1960s to five million pregnant women for the prevention of spontaneous abortion. (europa.eu)
  • In addition, a number of adverse changes have been suggested to have occurred in a population living near a chemical plant in Seveso, Italy as a result of the accidental release of the chemical dioxin, a suspected endocrine disruptor. (europa.eu)
  • Goal: To acquire and demonstrate the fund of knowledge and practical skills necessary to manage common and complex pediatric endocrine conditions in infants, children, and adolescents. (slideshare.net)
  • The program is directed by a senior endocrine pathologist, and supports the only ACGME approved Endocrine Pathology fellowship and the third ACGME-approved Head & Neck Pathology fellowship in the country. (yalecancercenter.org)
  • The significant insights and new diagnostic possibilities arising from recent discoveries in cellular and molecular biology are transforming the field of endocrine pathology. (springer.com)
  • In Endocrine Pathology: Differential Diagnosis and Molecular Advances, a panel of leading experts capture these dynamic changes by critically reviewing those molecular discoveries that can clarify the pathophysiology of endocrine disease processes and enhance the diagnosis of specific endocrine pathologies. (springer.com)
  • The main evidence suggesting that exposure to environmental chemicals can lead to disruption of endocrine function comes from changes seen in a number of wildlife species. (europa.eu)
  • Effects suggested as being related to endocrine disruption have been reported in molluscs, crustacea, fish, reptiles, birds and mammals in various parts of the world. (europa.eu)
  • Your body produces its own chemicals and uses them to control certain functions, and the main system that coordinates these chemicals is called the endocrine system . (kidshealth.org)
  • The ability of certain chemicals to interfere with endocrine function was realized in the mid-20th century, and synthetic pesticides were among the first to be studied. (britannica.com)
  • Since the 1960s and '70s, large numbers of endocrine-disrupting chemicals have been identified, and many of them are widely distributed in the environment . (britannica.com)
  • Although a number of them are herbicides , fungicides , or insecticides , a variety of industrial chemicals and some naturally occurring elements have also been discovered to be toxic to the endocrine system. (britannica.com)
  • Some chemicals can act on the endocrine system to disturb the homeostatic mechanisms of the body or to initiate processes at abnormal times in the life cycle. (europa.eu)
  • There is also some limited evidence in humans that adverse endocrine-mediated effects have followed either intentional or accidental exposure to high levels of particular chemicals. (europa.eu)
  • Laboratory experiments have suggested that some man-made chemicals might be able to cause endocrine changes. (europa.eu)
  • The endocrine system plays a role in regulating mood, growth and development, tissue function, metabolism, and sexual function and reproductive processes. (kidshealth.org)
  • Understanding the Nuanced Management of Acromegaly Acromegaly is a rare endocrine disorder that is often misunderstood. (medscape.com)
  • Endocrine and genetic causes of obesity viii. (slideshare.net)
  • Although not transmitted in the germline, McCune-Albright syndrome is a genetic disorder characterized by endocrine neoplastic features involving endocrine glands that overlap with those involved in MEN1 or MEN2. (wikipedia.org)
  • This cooperation between the nervous system and Effects of pituitary adenomas endocrine apparatus is referred to as neuroendocrine Pituitary adenomas cause problems because of a com- signalling. (slideshare.net)
  • Such a system may range, at its simplest, from the neurosecretory, involving one or more centres in the nervous system , to the complex array of glands found in the human endocrine system . (britannica.com)
  • It is both an endocrine and an exocrine gland. (berkeley.edu)
  • EPA implements screening, testing and research programs to gather information the Agency uses to evaluate possible endocrine effects associated with the use of a chemical. (epa.gov)