Tyrosineras GTPase-Activating Proteinsras ProteinsProtein Tyrosine Phosphatasesp120 GTPase Activating ProteinGTPase-Activating ProteinsProto-Oncogene Proteins p21(ras)GTP PhosphohydrolasesPoint MutationNeurofibromin 1Protein Tyrosine Phosphatase, Non-Receptor Type 1Mutation, MissenseSignal TransductionMutationMolecular Sequence DataGenes, rasAmino Acid SequencePhosphorylationProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 11Receptor-Like Protein Tyrosine Phosphatases, Class 2Protein Tyrosine Phosphatase, Non-Receptor Type 2Protein Tyrosine Phosphatase, Non-Receptor Type 6Protein-Tyrosine KinasesReceptor-Like Protein Tyrosine Phosphatases, Class 3PhosphotyrosineFrameshift MutationCell LineLymphocyte Specific Protein Tyrosine Kinase p56(lck)Receptor-Like Protein Tyrosine Phosphatases, Class 4VanadatesReceptor-Like Protein Tyrosine Phosphatases, Class 5Enzyme ActivationProtein Tyrosine Phosphatases, Non-ReceptorBase SequenceTyrosine 3-MonooxygenaseOncogene Protein p21(ras)Protein BindingGerm-Line MutationGenisteinProto-Oncogene ProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 12Intracellular Signaling Peptides and ProteinsProtein Structure, TertiaryPhosphoproteinsEnzyme InhibitorsTransfectionMutagenesis, Site-DirectedCells, CulturedSH2 Domain-Containing Protein Tyrosine Phosphatasessrc Homology DomainsReceptor Protein-Tyrosine KinasesBinding SitesPedigreeProtein Tyrosine Phosphatase, Non-Receptor Type 13Amino Acid SubstitutionRecombinant Fusion ProteinsKineticsProto-Oncogene Proteins c-fynSequence Homology, Amino AcidProto-Oncogene Proteins pp60(c-src)Guanosine TriphosphateMembrane ProteinsReceptor-Like Protein Tyrosine PhosphatasesRecombinant ProteinsPolymerase Chain Reactionsrc-Family KinasesReceptor-Like Protein Tyrosine Phosphatases, Class 7rho GTP-Binding ProteinsExonsCloning, MolecularMutation RateGTP-Binding ProteinsDNA Mutational AnalysisModels, MolecularCOS CellsDNA Primers3T3 CellsAdaptor Proteins, Signal TransducingHeterozygoteMutagenesisAllelesTyrphostinsBlotting, WesternReceptor, Epidermal Growth FactorDNA-Binding ProteinsRNA, MessengerTumor Cells, CulturedReceptor-Like Protein Tyrosine Phosphatases, Class 8Monomeric GTP-Binding ProteinsGuanine Nucleotide Exchange FactorsPhenotypeEscherichia colirab GTP-Binding ProteinsSequence DeletionProtein Tyrosine Phosphatase, Non-Receptor Type 22BenzoquinonesLactams, MacrocyclicCarrier ProteinsSubstrate Specificity