• These residues form part of the putative active site of CHAP domain containing proteins. (wikipedia.org)
  • Mouse IL-17C cDNA encodes a 194 amino acid (aa) residues protein with a putative 14 aa signal peptide (5). (rndsystems.com)
  • The enzymes contain ~250-300 residues, which encode putative signal sequences and carbohydrate attachment sites. (embl.de)
  • 1] "A Synechococcus gene encoding a putative pore-forming intrinsic membrane protein. (tcdb.org)
  • 1997). „Isolation and chromosomal localization of GPR31, a human gene encoding a putative G protein-coupled receptor. (wikipedia.org)
  • Analysis of two highly expressed genes from Chlorella virus PBCV-1: Protein characterization and the DNA sequences of the major capsid protein gene and the early/late 33-kDa protein gene. (uml.edu)
  • Putative Gene Promoter Sequences in the Chlorella Viruses. (uml.edu)
  • Interestingly, the hCTR sequence is remotely related to the cAMP receptor of Dictyostelium discoideum (21% identical), but is not significantly related to other G protein-coupled receptor sequences now in the data bases. (jci.org)
  • Of the 2,556 putative protein coding sequences in the P. salinus genome, 93% have no recognizable counterparts among known proteins. (virology.ws)
  • In conclusion, the authors detected and genetically characterized a putative novel Usutu virus strain (Usutu-BONN) by determining its complete genome sequence and comparing it with Usutu virus strains for which complete polyprotein-encoding sequences are available. (cdc.gov)
  • The cloned cDNA encodes a putative peptide of 490 amino acids with seven potential transmembrane domains. (jci.org)
  • Mutational genomics and targeted exome capture identify Sr26 and Sr61 as separate single genes that encode unrelated (34.8%) nucleotide binding site leucine rich repeat proteins. (nature.com)
  • Plant intracellular nucleotide binding and leucine-rich repeat proteins (NB-LRR, NLRs) function as immune receptors to detect microbial pathogens directly or indirectly. (ubc.ca)
  • The POF protein sequence contains a putative RNA-binding domain. (the-scientist.com)
  • PASS2 version 6: a database of structure-based sequence alignments of protein domain superfamilies in accordance with SCOPe. (ncbs.res.in)
  • RStrucFam: a web server to associate structure and cognate RNA for RNA-binding proteins from sequence information. (ncbs.res.in)
  • Recombinant protein encompassing a sequence within the center region of human RBPMS. (genetex.com)
  • The Interleukin 17 (IL-17) family proteins, comprising six members (IL-17, IL-17B through IL-17F), are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable sequence divergence at the N-terminus (1, 2). (rndsystems.com)
  • The described cDNA corresponds to a full-length mRNA encoding a protein of 582 amino acids, the first 32 of which constitute a putative mitochondrial targeting leader sequence. (bioone.org)
  • Full-length genome sequence of this putative novel Usutu virus strain, designated Usutu-BONN, was successfully attained. (cdc.gov)
  • 2006). „Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes." . (wikipedia.org)
  • Fabrizio Gianguzza , Maria Antonietta Ragusa , Maria Carmela Roccheri , Italia Di Liegro , and Anna Maria Rinaldi "Isolation and characterization of a Paracentrotus lividus cDNA encoding a stress-inducible chaperonin," Cell Stress & Chaperones 5(2), 87-89, (1 April 2000). (bioone.org)
  • Further characterization showed that susa2-2 only suppresses the autoimmunity mediated by either CHS1-SOC3 or TN2-SOC3 paired NLR proteins, indicating that SUSA2 is specifically involved in NLR protein SOC3-mediated immunity. (ubc.ca)
  • Purification and characterization of two protein kinases acting on the aquaporin SoPIP2;1. (lu.se)
  • The hOAT3 cDNA consisted of 2179 base pairs that encoded a 543-amino-acid residue protein with 12 putative transmembrane domains. (aspetjournals.org)
  • Although Doublecortin does not contain a kinase domain, it is homologous to the amino terminus of a predicted kinase protein, indicating a likely role in signal transduction. (nih.gov)
  • Sr60 is an exception that encodes a tandem kinase protein 10 . (nature.com)
  • The Parkinson's disease genes pink1 and parkin , which encode a mitochondrially targeted protein kinase, and an E3 ubiquitin ligase, respectively, participate in a key mitochondrial quality-control pathway that eliminates damaged mitochondria. (sdbonline.org)
  • Regardless of mutation type or allelic loss, the loss of expression of the NF2 protein, merlin, appears to be universal in schwannomas. (bmj.com)
  • Myelinating Schwann cells form a myelin sheath around a single axon and express high levels of myelin-related proteins and messenger RNA (mRNA). (medscape.com)
  • The gene defective in leukocyte adhesion deficiency II encodes a putative GDP-fucose transporter. (lu.se)
  • Comparative analysis has demonstrated that this protein is highly conserved in evolution. (bioone.org)
  • A cDNA encoding a multispecific organic anion transporter 3 (hOAT3) was isolated from a human kidney cDNA library. (aspetjournals.org)
  • RafK carries a C-terminal regulatory domain present in a subset of ATP-binding proteins that has been involved in both direct regulation of transporter activity (inducer exclusion) and transcription of transporter genes. (lu.se)
  • Many type IVa systems also encode a homolog of PilT called PilU. (biorxiv.org)
  • Bioinformatics comparisons of RNA-binding proteins of pathogenic and non-pathogenic Escherichia coli strains reveal novel virulence factors. (ncbs.res.in)
  • Similar to other strains, this putative novel Usutu virus strain was introduced into Europe by way of viremic migratory birds returning from winter migrations from Africa to Europe or through ship- or aircraft-borne transportation of Usutu virus infected mosquitos from Africa. (cdc.gov)
  • While some effector proteins specifically target bacterial or eukaryotic cells, others can target both types of cells (trans-kingdom effectors). (frontiersin.org)
  • Bioinformatic and comparative genomic analyses allowed us to identify genes encoding three candidate antibacterial effectors located within SPI-6 and two candidate effectors located within SPI-19. (frontiersin.org)
  • Of note, the genes encoding these effectors and immunity proteins are widely distributed in Salmonella genomes, suggesting a relevant role in interbacterial competition and virulence. (frontiersin.org)
  • The objective of this research is to determine the biochemical functions of Hessian fly effectors and their interacting proteins in wheat plants. (usda.gov)
  • Hessian fly larvae are thought to inject secreted salivary gland protein (SSGP) effectors into wheat seedlings to help obtain nutrients and dampen the host resistance response. (usda.gov)
  • We will use the pEAQ-HT-DEST1 protein transient expression vector system to screen for candidate effectors that can trigger measurable plant responses. (usda.gov)
  • Most NLRs guard host proteins that are the direct targets of pathogen effectors. (ubc.ca)
  • Some proteins known to contain a CHAP domain are listed below: Bacterial and trypanosomal glutathionylspermidine amidases. (wikipedia.org)
  • In this review, we assess the potential role of putative gut microbiota products in the etiopathogeny of Parkinson's disease, with a special emphasis on functional bacterial amyloid proteins, bacterial biosurfactants, endotoxins and short-chain fatty acids. (techscience.com)
  • In this strain, 1 putative cleavage site of the viral polyprotein responsible for processing of structural proteins was changed. (cdc.gov)
  • Streptococcus pneumoniae choline-binding protein D. Methanosarcina mazei protein MM2478, a putative chloride channel. (wikipedia.org)
  • While the specific function of this protein is not well understood, it belongs to a family of proteins, called anoctamins, that act as chloride channels. (medlineplus.gov)
  • The co-chaperone Hep1 is required to prevent the aggregation of mitochondrial Hsp70 proteins. (cipsm.de)
  • One isolate, PBCV-1, for example, (genome size = 330744 bp dsDNA) codes for ~375 proteins, nearly half of which resemble proteins of known function. (uml.edu)
  • Genome-wide survey of putative RNA-binding proteins encoded in the human proteome. (ncbs.res.in)
  • Sarah Gregory] The authors characterize the complete genome of the putative novel Usutu virus strain Usutu-BONN detected in a dead black bird from Germany. (cdc.gov)
  • A His-tag will be added to each recombinant protein to facilitate protein purification. (usda.gov)
  • Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. (antibodies-online.com)
  • The Type VI Secretion System (T6SS) is a multiprotein device that has emerged as an important fitness and virulence factor for many Gram-negative bacteria through the injection of effector proteins into prokaryotic or eukaryotic cells via a contractile mechanism. (frontiersin.org)
  • In addition, there is limited information regarding the repertoire of effector proteins encoded within T6SS SPI-6 and T6SS SPI-19 gene clusters in S . Dublin. (frontiersin.org)
  • Each antibacterial effector gene is located upstream of a gene encoding a hypothetic immunity protein, thus conforming an effector/immunity (E/I) module. (frontiersin.org)
  • Several genes encoding putative Hessian fly effector family 31 members have been cloned previously. (usda.gov)
  • these receptors comprise a distinct family of G protein-coupled seven transmembrane domain receptors. (jci.org)
  • The NMB0736 gene of Neisseria meningitidis serogroup B strain MC58 encodes the putative nitrogen regulatory protein, IIANtr (abbreviated to NM-IIANtr). (rcsb.org)
  • Protein conformation is critically linked to function and often controlled by interactions with regulatory factors. (cipsm.de)
  • Like RafK, the presence of DLDH also activated the expression of raf operon genes, as DLDH-negative pneumococci showed a significantly decreased expression of aga and rafEFG, but DLDH did not regulate rafK or the putative regulatory genes rafR and rafS. (lu.se)
  • Interestingly, functionally redundant SNIPER1 and SNIPER2 can control the protein levels of diverse sNLRs and the interactions between SNIPER1 and sNLRs appear to be through the common nucleotide-binding (NB) domains of sNLRs. (ubc.ca)
  • As a positive regulator of plant immunity, E3 ligase SAUL1 is guarded by NLR protein SOC3. (ubc.ca)
  • Preexisting antivector immunity can severely compromise the ability of Salmonella enterica serovar Typhimurium live vaccines to induce protective CD8 T-cell frequencies after type III secretion system-mediated heterologous protein translocation in orally immunized mice. (cipsm.de)
  • We identified a novel 10 kb brain-specific cDNA interrupted by a balanced translocation in an XLIS patient that encodes a novel 40 kDa predicted protein named Doublecortin. (nih.gov)
  • In molecular biology, the CHAP domain is a region between 110 and 140 amino acids that is found in proteins from bacteria, bacteriophages, archaea and eukaryotes of the family Trypanosomidae. (wikipedia.org)
  • To identify interacting targets, Hessian fly-infested and non-infested wheat extracts will be incubated with immobilized family 31 proteins. (usda.gov)
  • The molecules bound to recombinant family 31 proteins will be eluted and will be identified via liquid chromatography/mass spectrometry quadrupole time of flight (LC-Q-TOF) instrumentation. (usda.gov)
  • This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. (genetex.com)
  • All members of this family are encoded by genes polyhydroxyalkanoic acid (PHA) biosynthesis and utilization genes, including proteins at found at the surface of PHA granules. (nih.gov)
  • IL-17 family proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions (1, 2). (rndsystems.com)
  • Encodes a member of the KANADI family of putative transcription factors. (utoronto.ca)
  • Annotation of Selaginella moellendorffii major intrinsic proteins and the evolution of the protein family in terrestrial plants. (lu.se)
  • Here, we show that retraction of pili in some systems is determined by the combined activity of two motor ATPase proteins. (biorxiv.org)
  • All type IV pilus systems encode a predicted ATPase, often called PilB, that facilitates pilus extension [ 7 , 10 - 12 ]. (biorxiv.org)
  • Three transcript variants encoding two different isoforms have been found for this gene. (antibodies-online.com)
  • Alternative splicing results in multiple transcript variants encoding different isoforms. (genetex.com)
  • Many of these genes encode proteins (e.g., enzymes involved in protein glycosylation) rarely associated with viruses. (uml.edu)
  • Chaperonins are ubiquitous proteins that facilitate protein folding in an adenosine triphosphate-dependent manner. (bioone.org)
  • Affinity purified by Protein A. (genetex.com)
  • Affinity tags can reduce merohedral twinning of membrane protein crystals. (lu.se)
  • Here we demonstrate that PSRP1 is not a bona fide ribosomal protein, but rather a functional homologue of the Escherichia coli cold-shock protein pY. (cipsm.de)
  • [ 4 ] This locus contains several known genes including amelogenin Y ( AMELY ), RNA-binding motif ( RBM ), protein kinase Y ( PRKY ), protein tyrosine phosphatase ( PTP )-BL related Y ( PRY ), testis transcripts Y1 and Y2 ( TTY1 and TTY2 ), and testis-specific protein Y-encoded ( TSPY ). (medscape.com)
  • The encoded protein has a single, putative RNA recognition motif in its N-terminus. (genetex.com)
  • 2020. A knowledge-driven protocol for prediction of proteins of interest with an emphasis on biosynthetic pathways. . (ncbs.res.in)
  • Gnathodiaphyseal dysplasia is caused by mutations in the ANO5 gene, which provides instructions for making a protein called anoctamin-5. (medlineplus.gov)
  • The ANO5 gene mutations that have been identified in people with gnathodiaphyseal dysplasia change single protein building blocks (amino acids) in the anoctamin-5 protein. (medlineplus.gov)
  • Phylogenetic analysis demonstrated that Usutu bond constitutes a putative novel African Usutu virus lineage, which was probably, recently, introduced to Central Europe. (cdc.gov)
  • POF complexes may function like the Male Lethal Specific proteins, which regulate dosage-compensation of the X chromosome. (the-scientist.com)
  • It has been suggested that CHAP domain containing proteins utilise a catalytic cysteine residue in a nucleophilic-attack mechanism. (wikipedia.org)
  • However, the function of this protein has remained unclear because pilU mutants exhibit inconsistent phenotypes among type IV pilus systems and because it is relatively understudied compared to PilT. (biorxiv.org)
  • RBPMS antibody [HL1106] detects RBPMS protein at nucleus by immunohistochemical analysis. (genetex.com)
  • Plastid-specific ribosomal proteins (PSRPs) have been proposed to play roles in the light-dependent regulation of chloroplast translation. (cipsm.de)
  • The main aim of our research is to understand the molecular details and physiological roles of the multitude of water channel-like proteins present in plants and animals. (lu.se)
  • VCS encodes a putative WD-domain containing protein,suggesting a function involving protein-protein interactions. (biologists.com)
  • report the molecular cloning of Painting of fourth (Pof), which encodes a protein that specifically paints chromosome 4 (Proc Natl Acad Sci USA 2001, 98:6273-6278). (the-scientist.com)
  • POF protein decorates chromosome 4 by spreading out from an initiation site in the proximal region of the chromosome. (the-scientist.com)
  • In 1986, the NF2 gene was mapped to chromosome 22, and in 1993, two groups independently isolated the gene and named its encoding protein merlin or schwannomin. (bmj.com)
  • The hOAT3 protein was shown to be localized in the basolateral membrane of renal proximal tubules and the hOAT3 gene was determined to be located on the human chromosome 11q12-q13.3 by fluorescent in situ hybridization analysis. (aspetjournals.org)
  • Merlin has high homology with the ERM proteins (ezrin, radixin, and moesin) and shares an amino-terminal domain. (bmj.com)
  • Type IV pili are composed almost exclusively of a single protein called the major pilin, which forms a helical fiber that extends from the cell surface [ 6 ]. (biorxiv.org)
  • Here we report the selection of camelid-derived single-domain antibodies (nanobodies) that modulate the conformation and spectral properties of the green fluorescent protein (GFP). (cipsm.de)
  • Now a large and ever increasing number of genetic subtypes has been described, and major advances in molecular and cellular biology have clarified the understanding of the role of different proteins in the physiology of peripheral nerve conduction in health and in disease. (medscape.com)