AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation Science
p38 Mitogen-Activated Protein KinasesMitogen-Activated Protein KinasesMAP Kinase Signaling SystemEnzyme ActivationMitogen-Activated Protein Kinase KinasesMitogen-Activated Protein Kinase 1PhosphorylationSignal TransductionMitogen-Activated Protein Kinase 3ImidazolesMitogen-Activated Protein Kinase 14PyridinesEnzyme InhibitorsExtracellular Signal-Regulated MAP KinasesJNK Mitogen-Activated Protein KinasesCalcium-Calmodulin-Dependent Protein KinasesFlavonoidsDual Specificity Phosphatase 1ButadienesCells, CulturedMAP Kinase Kinase 3MAP Kinase Kinase KinasesProtein-Serine-Threonine KinasesNitrilesBlotting, WesternMAP Kinase Kinase 4Cell LineProto-Oncogene Proteins c-rafPhosphatidylinositol 3-Kinasesras ProteinsMAP Kinase Kinase 2ApoptosisCell Line, TumorMitogen-Activated Protein Kinase 11Proto-Oncogene Proteins c-aktProtein-Tyrosine KinasesNF-kappa BRNA, MessengerGene Expression RegulationCell ProliferationRats, Sprague-DawleyUp-RegulationProtein Kinase CTransfectionProtein Phosphatase 1Ribosomal Protein S6 Kinases, 90-kDaModels, BiologicalDose-Response Relationship, DrugProtein KinasesCell SurvivalGene Expression Regulation, EnzymologicProtein Tyrosine PhosphatasesMitogen-Activated Protein Kinase 6Tumor Necrosis Factor-alphaIntracellular Signaling Peptides and Proteinsraf KinasesAnisomycinActivating Transcription Factor 2RNA, Small InterferingReverse Transcriptase Polymerase Chain ReactionMitogen-Activated Protein Kinase 8Transcription Factor AP-1AnthracenesTime FactorsReactive Oxygen SpeciesDown-RegulationCyclic AMP Response Element-Binding ProteinMAP Kinase Kinase Kinase 1Proto-Oncogene ProteinsCell DivisionMitogen-Activated Protein Kinase 9Cell DifferentiationCyclooxygenase 2LipopolysaccharidesHSP27 Heat-Shock ProteinsTranscription FactorsMutationMice, Inbred C57BLFibroblastsEpidermal Growth FactorMolecular Sequence DataProtein BindingPhosphoprotein PhosphatasesEpithelial CellsAdaptor Proteins, Signal TransducingImmunoblottingMitogen-Activated Protein Kinase 12Receptor, Epidermal Growth FactorMitogen-Activated Protein Kinase PhosphatasesMitogen-Activated Protein Kinase 7ChromonesDual Specificity Phosphatase 6Mitogen-Activated Protein Kinase 13Mice, KnockoutMAP Kinase Kinase Kinase 5MAP Kinase Kinase 7Transcription, GeneticCell NucleusAmino Acid SequenceProto-Oncogene Proteins B-raf
ProteasesProteinTranslocateDifferentiationProteinsImmuneMutationsRegulatorAnalysesChromosomeComplexInteractionExpressionCellsProcessCell
Proteases1
  • 2013). This involves the crosslinking of keratinocyte proteins such as loricrin and involucrin by transglutaminases and the breakdown of the nucleus and other organelles by intracellular and secreted proteases (Eckhart et al. (uni-freiburg.de)
Protein8
  • Bioinformatic analyses of differential proteins were performed included Gene Ontology (GO) enrichment, pathway enrichment and protein-protein interaction network analysis. (jneuropsychiatry.org)
  • Description: Description of target: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. (apoptosises.com)
  • RAS family proteins include 23 genes coding for at least 25 proteins that are divided into eight paralog groups based on sequence identity, structure, and function: RAS, RAS-like (RAL), RAS-related protein (R-RAS), RAS-like protein in tissues (RIT), RAS-related protein Rap (RAP), RAS homolog enriched in brain (RHEB), Dexamethasone-induced RAS-related protein (RASD), and GTP-binding protein Di-RAS (DIRAS) [ 5 ] . (encyclopedia.pub)
  • with Pubmed ID, gene symbol/accession number and viral interacting protein. (polygenicpathways.co.uk)
  • The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. (cancerindex.org)
  • What does this gene/protein do? (cancerindex.org)
  • The protein encoded by this gene is a member of the BCL-2 family. (affbiotech.com)
  • The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. (affbiotech.cn)
Translocate2
  • colorectal genes translocate about works for NAT. (evakoch.com)
  • G-/GMCSF activates the JAK family of receptor tyrosine kinases, which unfolds its activity by not only regulating enzymes and target proteins within its local milieu, but importantly also by activating the STAT family of transcription factors, which subsequently dimerize and translocate to the cell nucleus to regulate gene expression[ 13 ]. (biomedcentral.com)
Differentiation2
  • Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. (apoptosises.com)
  • 2014). Loricrin and involucrin are encoded in 'Epidermal Differentiation Complex' linked to a large number of genes encoding nonredundant components of the CE (Kypriotou et al. (uni-freiburg.de)
Proteins1
  • The paralog group of RAS proteins is composed of four isoforms (H-RAS, N-RAS, K-RAS4A, and K-RAS4B) that are encoded by three genes, H-RAS , N-RAS , and K-RAS [ 6 ] . (encyclopedia.pub)
Immune1
  • However, there are other benefits that are provided by lactation, such as the provision of immune factors that are secreted into the milk, which provide protection from infection, and also the close contact that occurs between mother and infant during nursing, which might have developmental benefits (Peaker et al. (biologists.com)
Mutations1
  • Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. (apoptosises.com)
Regulator1
  • The disease is associated with single amino acid changes (A7V, A9V or A33P) in myofibrillogenesis regulator 1 (MR-1) on chromosome 2q35 which is the causative gene of PNKD [ 6 - 10 ]. (jneuropsychiatry.org)
Analyses1
  • We present complete information on regulated genes and validated profiling analyses and report novel regulatory networks and interaction maps revealed by detailed bioinformatics analyses. (biomedcentral.com)
Chromosome1
  • S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. (cancerindex.org)
Complex1
  • The bags of the two signaling hours affect negatively describe at the download insurgency and counterinsurgency and create simply identified together by an active complex secreted a endothelium serum. (erik-mill.de)
Interaction1
  • phosphorylated genes of the RUNX1: Neurotrophin interaction are involved in the complement of other disease of important tubules. (erik-mill.de)
Expression2
  • METHODS: The mRNA and miRNA expression data from the LUAD and normal control were obtained from Gene Expression Omnibus (GEO) database, TargetScan and mirDIP were applied to predict the relationship between miR-6742-5p and FGF8.Q-PCR, western blot, dual-luciferase, wound Healing and transwell assays were performed to test the functions of miR-6742-5p in LUAD. (bvsalud.org)
  • Search the gene expression profiles from curated DataSets in the Gene Expression Omnibus (GEO) repository. (cancerindex.org)
Cells2
  • FGF8 gene silencing in SKOV3 cells adversely affected various cell properties essential for cancer cell survival and metastasis. (bvsalud.org)
  • Several types of non-hematopoietic tumors secrete hematopoietic colony stimulating factors, which act on myeloid cells and tumor cells[ 7 ]. (biomedcentral.com)
Process1
  • today Factor C instead is, and DNA process trafficking encodes and requires the Th2 cumulus of DNA. (erik-mill.de)
Cell1
  • RESULTS: Bioinformatics analysis and dual-luciferase identified FGF8 is the target-gene of miR-6742-5p, which is declined in LUAD of human tissues and cell lines, and miR-6742-5P OE suppressed the progression of LUAD in nude mice. (bvsalud.org)