Encodes a protein checkpoint kinase cell cycle checkpoint gene. Medical search. Frequent questions

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Anatomy19

Spindle Apparatus Cell Line, Tumor Kinetochores HeLa Cells Cell Line Fibroblasts Cell Nucleus Tumor Cells, Cultured Cells, Cultured HCT116 Cells Chromosomes, Fungal Chromatin Centrosome Telomere Microtubules Chromosomes Cell Line, Transformed Blastula Cytoplasm

Organisms4

Schizosaccharomyces Saccharomyces cerevisiae Mice, Knockout Saccharomycetales

Diseases11

Chromosomal Instability Ataxia Telangiectasia Genomic Instability Aneuploidy Polyploidy Neoplasms Chromosome Breakage Cell Transformation, Neoplastic Chromosome Aberrations Breast Neoplasms Colonic Neoplasms

Chemicals and Drugs125

Checkpoint Kinase 2 Cell Cycle Proteins Protein-Serine-Threonine Kinases Protein Kinases Ataxia Telangiectasia Mutated Proteins Hydroxyurea DNA-Binding Proteins Nuclear Proteins Saccharomyces cerevisiae Proteins Schizosaccharomyces pombe Proteins cdc25 Phosphatases Tumor Suppressor Proteins Tumor Suppressor Protein p53 CDC2 Protein Kinase Fungal Proteins Intracellular Signaling Peptides and Proteins Cyclin B Mad2 Proteins Cyclin-Dependent Kinase Inhibitor p21 Nocodazole Cyclins Protein Kinase Inhibitors DNA, Fungal Phosphatidylinositol 3-Kinases Histones Cyclin-Dependent Kinases Methyl Methanesulfonate Cyclin B1 RNA, Small Interfering Cyclin-Dependent Kinase 2 Cdc20 Proteins BRCA1 Protein Repressor Proteins DNA CDC2-CDC28 Kinases Retinoblastoma Protein CDC28 Protein Kinase, S cerevisiae Protein-Tyrosine Kinases Caffeine Nucleic Acid Synthesis Inhibitors Aurora Kinases Aphidicolin Calcium-Binding Proteins Replication Protein A Carrier Proteins Chromosomal Proteins, Non-Histone Antineoplastic Agents Enzyme Inhibitors Staurosporine Chromatin 14-3-3 Proteins Neoplasm Proteins DNA Repair Enzymes Cyclin E Calcium-Calmodulin-Dependent Protein Kinases DNA-Activated Protein Kinase Proto-Oncogene Proteins Recombinant Fusion Proteins Transcription Factors Cyclin A Cyclin-Dependent Kinase Inhibitor p27 Radiation-Sensitizing Agents Exodeoxyribonucleases Mimosine DNA Primers Serine Phosphoprotein Phosphatases Ubiquitin-Protein Ligase Complexes Anaphase-Promoting Complex-Cyclosome DNA Helicases RNA, Messenger Phosphoproteins src-Family Kinases Proliferating Cell Nuclear Antigen Adaptor Proteins, Signal Transducing Rad51 Recombinase Cyclin-Dependent Kinase 4 p38 Mitogen-Activated Protein Kinases Exonucleases Recombinant Proteins Protein Kinase C Aurora Kinase B Mutagens Topoisomerase I Inhibitors Endodeoxyribonucleases Endonucleases Thioguanine Threonine Cyclin D1 Mitogen-Activated Protein Kinase 1 Poly(ADP-ribose) Polymerases Cyclic AMP-Dependent Protein Kinases Proteins Xenopus Proteins Camptothecin Mitogen-Activated Protein Kinase Kinases JNK Mitogen-Activated Protein Kinases 1-Naphthylamine Mitogen-Activated Protein Kinase 3 Bromodeoxyuridine p21-Activated Kinases Phosphoserine Antineoplastic Agents, Phytogenic Microtubule-Associated Proteins MAP Kinase Kinase Kinases Cyclin-Dependent Kinase Inhibitor p16 Casein Kinase II MAP Kinase Kinase 1 Securin Proto-Oncogene Proteins c-mdm2 Mitogen-Activated Protein Kinases Creatine Kinase DNA, Complementary Extracellular Signal-Regulated MAP Kinases Thiophenes Proto-Oncogene Proteins c-myc eIF-2 Kinase Ribosomal Protein S6 Kinases Casein Kinases Phosphothreonine Allyl Compounds MAP Kinase Kinase 4 Pyruvate Kinase Methylnitronitrosoguanidine Thymidine Kinase

Analytical, Diagnostic and Therapeutic Techniques and Equipment17

Models, Biological Flow Cytometry Blotting, Western Transfection Immunoblotting Dose-Response Relationship, Radiation Microscopy, Fluorescence Models, Genetic Gene Knockdown Techniques Two-Hybrid System Techniques Immunoprecipitation Cloning, Molecular Precipitin Tests Reverse Transcriptase Polymerase Chain Reaction Fluorescent Antibody Technique Gene Expression Profiling Immunohistochemistry

Phenomena and Processes88

Cell Cycle Genes, cdc DNA Damage G2 Phase Cell Cycle Checkpoints Mitosis S Phase M Phase Cell Cycle Checkpoints G2 Phase Cell Cycle Checkpoints DNA Repair DNA Replication Phosphorylation G1 Phase Mutation Gamma Rays Radiation, Ionizing Ultraviolet Rays S Phase Cell Cycle Checkpoints Apoptosis Chromosomal Instability Signal Transduction Genomic Instability Cell Division Kinetochores Genes, Fungal Radiation Tolerance DNA Breaks, Double-Stranded G1 Phase Cell Cycle Checkpoints Protein Binding Gene Deletion Base Sequence MAP Kinase Signaling System Amino Acid Sequence Cell Survival Enzyme Activation Cell Proliferation Aneuploidy Chromosome Segregation RNA Interference Phenotype Transfection Chromosomes, Fungal Metaphase Protein Structure, Tertiary Polyploidy Time Factors Genes, p53 Chromatin Anaphase Alleles Telomere Sequence Homology, Amino Acid Gene Expression Regulation, Neoplastic Gene Expression Regulation Dose-Response Relationship, Radiation Meiosis Recombination, Genetic Down-Regulation Gene Expression Regulation, Fungal Chromosomes Cell Death Transcription, Genetic Chromosome Breakage Interphase Kinetics Dose-Response Relationship, Drug X-Rays Chromosome Aberrations Protein Processing, Post-Translational Amino Acid Motifs Gene Expression Protein Transport Mutagenesis Gene Silencing Binding Sites Infrared Rays Ploidies Cell Aging Menstrual Cycle Promoter Regions, Genetic Genotype G0 Phase Replication Origin Cell Differentiation Sequence Deletion Base Pair Mismatch Catalytic Domain Substrate Specificity

Disciplines and Occupations1

Immunohistochemistry

Information Science3

Molecular Sequence Data Base Sequence Amino Acid Sequence

Health Care3

Ultraviolet Rays Dose-Response Relationship, Radiation Infrared Rays

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

Checkpoint Kinase 2 Cell Cycle Cell Cycle Proteins Genes, cdc DNA Damage Protein-Serine-Threonine Kinases Protein Kinases G2 Phase Cell Cycle Checkpoints Mitosis Ataxia Telangiectasia Mutated Proteins S Phase M Phase Cell Cycle Checkpoints Hydroxyurea Spindle Apparatus G2 Phase Cell Cycle Checkpoints DNA Repair DNA Replication DNA-Binding Proteins Nuclear Proteins Saccharomyces cerevisiae Proteins Phosphorylation Schizosaccharomyces Schizosaccharomyces pombe Proteins cdc25 Phosphatases G1 Phase Tumor Suppressor Proteins Mutation Tumor Suppressor Protein p53 CDC2 Protein Kinase Saccharomyces cerevisiae Gamma Rays Fungal Proteins Radiation, Ionizing Intracellular Signaling Peptides and Proteins Ultraviolet Rays S Phase Cell Cycle Checkpoints Cyclin B Mad2 Proteins Apoptosis Chromosomal Instability Cyclin-Dependent Kinase Inhibitor p21 Ataxia Telangiectasia Signal Transduction Genomic Instability Cell Division Cell Line, Tumor Nocodazole Cyclins Kinetochores HeLa Cells Molecular Sequence Data Protein Kinase Inhibitors Genes, Fungal Radiation Tolerance DNA, Fungal DNA Breaks, Double-Stranded Cell Line Models, Biological Phosphatidylinositol 3-Kinases Histones Cyclin-Dependent Kinases G1 Phase Cell Cycle Checkpoints Methyl Methanesulfonate Cyclin B1 Protein Binding Fibroblasts Gene Deletion RNA, Small Interfering Base Sequence MAP Kinase Signaling System Cyclin-Dependent Kinase 2 Cell Nucleus Amino Acid Sequence Cdc20 Proteins Flow Cytometry Cell Survival Enzyme Activation BRCA1 Protein Cell Proliferation Repressor Proteins DNA Tumor Cells, Cultured CDC2-CDC28 Kinases Retinoblastoma Protein CDC28 Protein Kinase, S cerevisiae Aneuploidy Protein-Tyrosine Kinases Chromosome Segregation RNA Interference Blotting, Western Caffeine Phenotype Nucleic Acid Synthesis Inhibitors Cells, Cultured Aurora Kinases Aphidicolin HCT116 Cells Calcium-Binding Proteins Transfection

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