Encoded in the nucleus. Medical search. Frequent questions

The tumor suppressor gene overgrown hematopoietic organs-31 (oho31) of Drosophila encodes a protein with extensive homology to the Importin protein of Xenopus (50% identity), the related yeast SRP1 protein, and the mammalian hSRP1 and RCH1 proteins. (rupress.org)
The gene encodes a phosphoprotein of 522 amino acids made of three domains: a central hydrophobic domain of eight repeats of 42-44 amino acids each, displaying similarity to the arm motif found in junctional and nucleopore complex proteins, and flanked by two hydrophilic NH2- and COOH-terminal domains. (rupress.org)
Plants contain nuclear gene families that encode proteins related to the principal sigma factors of eubacteria. (oregonstate.edu)
It imports hundreds of nucleus-encoded proteins, and diverse metabolites are continuously exchanged across the two chromatophore envelope membranes. (frontiersin.org)
Furthermore, chromatophore-localized biosynthetic pathways as well as multiprotein complexes include proteins of dual genetic origin, suggesting that mechanisms evolved that coordinate gene expression levels between chromatophore and nucleus. (frontiersin.org)
It is interesting because, unlike most viruses, it contains genes that encode for proteins involved in DNA packaging. (eurekalert.org)
The Medusavirus has a full set of histones, which are proteins that have evolved to keep the DNA folded inside the nucleus and regulate gene expression. (eurekalert.org)
The nucleus encodes the remaining proteins. (cytochemistry.net)
The genes encoding the red- and green-color-detecting proteins of the human eye are located next to one another on the X chromosome and probably evolved from a common ancestral pigment gene. (quizlet.com)
Chloroplast-located proteins which are encoded by the nuclear genome have to be imported from the cytosol into the organelle in a post-translational manner. (cipsm.de)
Among these nuclear-encoded chloroplast proteins are the light-harvesting chlorophyll a/b-binding proteins (LHCPs). (cipsm.de)
These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. (origene.com)
Lamin A and lamin C are structural filament proteins in the cell nucleus, encoded by the gene LMNA . (msdmanuals.com)

This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. (antikoerper-online.de)

We wanted to distinguish whether VPm neurons encode similar stimulus features, acting as a single information channel, or encode diverse features. (open.ac.uk)
By imaging cellular activity in the corticorecipient shell of the inferior colliculus of mice engaged in a sound detection task, we show that the majority of neurons encode information beyond the physical attributes of the stimulus and that the animals' behavior can be decoded from the activity of those neurons with a high degree of accuracy. (elifesciences.org)

But viral vectors are risky--they can enter the nucleus during cell division and disrupt genes. (the-scientist.com)
this could mean that during the coevolution, the virus might have acquired the genes that encode these histones. (eurekalert.org)
The Parkinson's disease genes pink1 and parkin , which encode a mitochondrially targeted protein kinase, and an E3 ubiquitin ligase, respectively, participate in a key mitochondrial quality-control pathway that eliminates damaged mitochondria. (sdbonline.org)
Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. (nih.gov)
Moreover, two NF-kB-regulated genes encoding pro-fibrotic mediators, tissue inhibitor of metalloproteinase 1 (TIMP1), and osteopontin (OPN), respectively, were significantly induced in lung fibroblasts and myofibroblasts. (cdc.gov)
Non-receptor tyrosine kinases encoded by the C-ABL GENES. (bvsalud.org)

During the interphase of early embryonic cell cycles, the OHO31 protein is present in the cytoplasm and massively accumulates in the nucleus at the onset of mitosis in late interphase and prophase. (rupress.org)
However, in the above view, they are dual labeled for Cre-recombinase with dylight 594 (red) in the nuclei and cytoplasm. (cytochemistry.net)
This makes the nuclei purple and the cytoplasm yellow. (cytochemistry.net)
The RNA strand is then modified so that it can leave the nucleus and be translated into a protein within the cell's cytoplasm. (bioedonline.org)
While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. (origene.com)
They are distributed in both the cytoplasm and the nucleus. (bvsalud.org)

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. (prosci-inc.com)
The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. (origene.com)

We already have many examples ure of a discrete action (lever press) to in the sensitivity of nucleus accumbens of how brain biology can affect behav- produce the expected results (cocaine). (lu.se)
Extinction-induced upregula- the work of Sutton et al .3, it has consid- of calcium into nucleus accumbens neu- tion in AMPA receptors reduces cocaine-seeking behaviour. (lu.se)
Altered responsiveness to co- oup the nucleus accumbens reflect the behavioral approaches that incorporate caine and increased immobility in the forced swim test associated with elevated cAMP response ele- memory of associations between the extinction-like processes may have effi- ment binding protein in nucleus accumbens. (lu.se)
Selective encoding of cocaine versus natural rewards by nucleus accumbens neurons is not related to chronic drug exposure. (bvsalud.org)

Here, the role of LGN bursts in encoding correlated natural stimuli was investigated by analyzing the responses of LGN neurons to natural scene movies. (jneurosci.org)
Black neurons: OT layer 10 (OT 10 ) neurons encoding these stimuli and providing excitatory input to Imc neurons (red ovals). (nature.com)
Somatosensory encoding with cuneate nucleus microstimulation: Detection of artificial stimuli. (nih.gov)
To date, however, how this system encodes the self-motion stimuli that are experienced during everyday activities remains unknown. (elifesciences.org)

COX subunits are encoded in both the nuclear and mitochondrial genomes. (wikipedia.org)
The three subunits that form the COX catalytic core are encoded in the mitochondrial genome. (wikipedia.org)
Though the interactions between subunits I, II, and III encoded within the mitochondrial genome make a lesser contribution to enzyme stability than interactions between bigenomic subunits, these subunits are more conserved, indicating potential unexplored roles for enzyme activity. (wikipedia.org)
This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. (nih.gov)
Since the gene cannot be read by the mitochondrial transcription machinery, the only way this yeast strain can survive in the absence of tryptophan is if the TRP1 gene moves from the mitochondrion to the nucleus. (yeastgenome.org)
Epigenetic Reader BRD4 (Bromodomain-Containing Protein 4) Governs Nucleus-Encoded Mitochondrial Transcriptome to Regulate Cardiac Function. (bvsalud.org)

Alternative splicing results in multiple transcript variants encoding distinct isoforms. (nih.gov)
Due to independent gene duplications, all organisms possess two isoforms, Oxa1 and Oxa2 except gram-negative bacteria, which encode only for one YidC-like protein. (cipsm.de)
The genome of Arabidopsis thaliana however, encodes for eight different isoforms. (cipsm.de)
Two alternatively spliced transcript variants encoding distinct isoforms have been reported. (prosci-inc.com)
Four transcript variants encoding different isoforms have been found for this gene. (nih.gov)

Subunits encoded in the nuclear genome are known to play a role in enzyme dimerization and stability. (wikipedia.org)

The sequence of the four nucleotide bases encodes DNA's information. (genome.gov)

Although most of a eukaryotic cell's DNA is contained in the cell nucleus , the mitochondrion has its own genome ("mitogenome") that is substantially similar to bacterial genomes. (wikipedia.org)
Lamin A helps to maintain the normal structure of a cell's nucleus, the cellular repository of genetic information. (sciencedaily.com)

They had vesicular nuclei with distinct nucleoli and typically exhibited a range of nuclear atypia in the same case. (lww.com)

The symptoms due to herniated nucleus pulposus (HNP) can ultimately be attributed to the significant inflammatory response it generates inside the spinal canal. (medscape.com)
[ 7 ] They proposed that herniation of the nucleus pulposus and displacement of nuclear material caused neural irritation, inflammation, and pain. (medscape.com)
The aim of this study was to determine the developmental origins of nucleus pulposus cells within the intervertebral disc using a novel notochord-specific Cre mouse. (bepress.com)
Fate mapping studies demonstrated that, following elongation and formation of the primitive axial skeleton, the notochord gives rise to the nucleus pulposus in fully formed intervertebral discs. (bepress.com)
Cellular localization of β-galactosidase (encoded by lacZ) and cytokeratin-8 demonstrated that both notochordal cells and chondrocyte-like nucleus pulposus cells are derived from the embryonic notochord. (bepress.com)
These studies establish conclusively that notochordal cells act as embryonic precursors to all cells found within the nucleus pulposus of the mature intervertebral disc. (bepress.com)

Nucleic Acids and Nucleotides - Nucleic Acids and Nucleotides Nucleic acids are long, slightly acidic molecules originally identified in cell nuclei. (powershow.com)

Moreover, the cell cycle-dependent accumulation of OHO31 in the nucleus indicates that this protein may be required for critical nuclear reactions occurring at the onset of mitosis. (rupress.org)
Sometimes this mtDNA can end up in the nucleus and find its way into nuclear DNA. (yeastgenome.org)

We aimed to determine the nature of the tactile information encoded by neurons in the whisker somatosensory relay nucleus (VPm). (open.ac.uk)

mRNA synthesis is directed by information encoded on DNA. (powershow.com)

OT: optic tectum, Imc: nucleus isthmi pars magnocellularis, FB: forebrain. (nature.com)
Acetylcholine (ACh) is thought to facilitate cortical plasticity during memory formation and its release is regulated by the nucleus basalis magnocellularis (NBM). (jneurosci.org)
This ACh release is controlled by the nucleus basalis magnocellularis (NBM) in the basal forebrain ( Miranda and Bermúdez-Rattoni, 1999 ). (jneurosci.org)

Progerin is a mutated version of a normal cellular protein called lamin A, which is encoded by the normal LMNA gene. (sciencedaily.com)

Our results showed that the coding sequence of EZH2 was 2241 bp, encoding 746 amino acids. (hindawi.com)

The overgrown hematopoietic organs-31 tumor suppressor gene of Drosophila encodes an Importin-like protein accumulating in the nucleus at the onset of mitosis. (rupress.org)
YME1 had been shown to be an important suppressor mtDNA migration to the nucleus. (yeastgenome.org)

Some of these RNA molecules were encoded by one particular gene, mCAT2. (bioedonline.org)

When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. (prosci-inc.com)

When the Medusavirus petrifies the amoeba, it does so by hijacking the cell directly from its nucleus. (eurekalert.org)
The diploid nucleus from the cell was extracted and then injected into an enucleated egg. (quizlet.com)
It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. (cancerindex.org)
Inside the cell nucleus, DNA gets transcribed into messenger RNA. (bioedonline.org)
The combination of genetically encoded biosensors with BacMam delivery technology yields robust and easy-to-use cell-based assays. (thermofisher.com)
One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)
When the nucleus of a stem cell has been the technique of cloning. (who.int)
The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)

With the Medusavirus, scientists discovered that DNA replication occurred in the nucleus of the host amoeba and observed evidence of exchange of genetic information between the host and the virus as they coevolved. (eurekalert.org)
We inherit genetic information from our parents encoded in the DNA sequence. (mpg.de)
A codon is a DNA or RNA sequence of three nucleotides (a trinucleotide) that forms a unit of genetic information encoding a particular amino acid. (genome.gov)

The members of the Toc159 family of GTPases act as the primary receptors for the import of nucleus-encoded preproteins into plastids. (rupress.org)

Temporal lobe interictal spikes disrupt encoding and retrieval of verbal memory: a subregion analysis. (neurotree.org)

In clinical trials, a herpes simplex gene encoding the enzyme thymidine kinase (TK) is delivered, via a retrovirus vector, to dividing brain cancer (glioma) cells. (the-scientist.com)
The T7 vector never enters the nucleus, and it continuously produces the enzyme. (the-scientist.com)

A chronic neural interface to the macaque dorsal column nuclei. (nih.gov)

Pituitary gonadotropes are immunolabeled fluorescent green for LH (see above banner) and nuclei stain blue with DAPI. (cytochemistry.net)

Given that YME1L1 was mutated in just a subset of the cancers, it is unlikely that it is the only player in the mtDNA these authors found in the nuclei of cancer cells. (yeastgenome.org)
The neoplastic cells showed variable expression of FDC markers and were labeled for Epstein-Barr virus-encoded RNA on in situ hybridization. (lww.com)
Many nucleosomes join together to form the "chromatin" located in the nucleus of all cells. (mpg.de)
The team had noticed some unmodified messenger RNAs lingering in the nucleus of mouse cells, inside tiny protein structures called paraspeckles. (bioedonline.org)
Phosphorylated NF-kB p65 at serine 276, a marker of NF-kB activation, was markedly induced by MWCNTs in the nucleus of fibroblastic cells. (cdc.gov)

In order to investigate the comet nucleus and the gas and dust ejected from the nucleus as the comet approaches the Sun, Rosetta carries a suite of eleven instruments on the comet orbiter and Philae, a lander equipped with a further ten instruments which perform surface measurements. (esa.int)

This gene encodes a member of the trithorax group of transcriptional activators. (cancerindex.org)

Therefore ZmSig2B is an unusual nucleus-encoded sigma factor that appears to function in both chloroplasts and mitochondria. (oregonstate.edu)

Prokineticin 2 and its receptor are active in a region of the brain called the suprachiasmatic nucleus (SCN), which acts as an internal clock that controls circadian rhythms. (medlineplus.gov)

as a result, the nucleus becomes herniated, leading to the subsequent manifestation of clinical symptoms. (medscape.com)

As a final experiment, they used a yeast strain, yme1-1 , in which YME1 function was inactivated, to show that the human homologue, YME1L1, could suppress the migration of mtDNA to the nucleus. (yeastgenome.org)

A nucleus-encoded maize protein with sigma factor activity accumulates in mitochondria and chloroplasts. (oregonstate.edu)
Since PBN response fields are retinotopically organized, our results suggest that activity foci associated with real and virtual targets at a given target position lie in the same physical location in the PBN, i.e., a retinotopic as well as a rate encoding of virtual-target position. (elsevierpure.com)

To analyse the time-series 3D microscopic images of developing embryos with fluorescently labelled nuclei, these studies used image segmentation. (nature.com)

Accordingly, here we directly addressed how otolith afferents encode the gravito-inertial forces experienced during everyday activities. (elifesciences.org)

Anatomy102

Organisms13

Diseases1

Chemicals and Drugs55

Analytical, Diagnostic and Therapeutic Techniques and Equipment32

Psychiatry and Psychology8

Phenomena and Processes46

Disciplines and Occupations3

Information Science4

Health Care1

Proteins13

Gene encodes a phosphoprotein1

Neurons encode2

Genes6

Cytoplasm6

Protein encoded by this gene2

Accumbens4

Stimuli4

Mitochondrial6

Isoforms5

Subunits1

Nucleotide1

Cell's2

Vesicular1

Pulposus6

Nucleic1

Nuclear2

Somatosensory1

MRNA1

Magnocellularis3

LMNA1

Coding sequence1

Suppressor2

Molecules1

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Cell8

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Disrupt1

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