Encode novel proteins peptides carrier proteins. Medical search. Frequent questions

The AVP gene promoter region consists of an E-box element located 150 residues upstreams of the transcription start site, which binds mammalian clock proteins CLOCK and BMAL1 involved in generating circadian rhythms in the suprachiasmatic nucleus (SCN). (wikipedia.org)
BMAL1 and CLOCK gene knockouts in the SCN (Bmal-/- and clk-/-) eliminate rhythmicity in AVP mRNA expression, confirming that binding of the protein heterodimers to the E-box element is necessary for the intrinsic circadian pattern of the AVP gene. (wikipedia.org)
Daily rhythms in the phosphorylation of the CRE binding protein (CREB) supports that these elements also contribute to circadian rhythmicity of the gene expression. (wikipedia.org)
The NPR2 gene encodes the natriuretic peptide receptor B (NPR-B) protein, also called guanylate cyclase B (GC-B). NPR-B is expressed in many tissues, including cells in the growth plates of growing bones. (childrenshospital.org)
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. (nature.com)
Using these variants, we map and validate gene-disease associations in two independent biobanks containing exome sequencing from 10,900 and 32,268 individuals, respectively, and elucidate their impact on protein expression in human cells. (nature.com)
The protein encoded by this gene is a pH-sensitive sodium-dependent phosphate transporter. (caslab.com)
Three transcript variants encoding two different isoforms have been found for this gene. (caslab.com)
Two genetic variants in strong linkage disequilibrium (rs9536314 and rs9527025) in the Klotho (KL) gene, encoding a transmembrane protein, implicated in longevity and associated with brain resilience during normal aging, were recently shown to be associated with Alzheimer disease (AD) risk in cognitively normal participants who are APOE ε4 carriers. (lu.se)
An alternative transcript of CALCA encodes the precursor for the neuropeptide called Calcitonin gene-related peptide 1, also designated CGRP1 or -CGRP. (zeta-corp.com)
In humans the protein is encoded by a single gene found near the inversion telomere of a large inverted region of CHROMOSOME 5. (harvard.edu)
Mutations in the gene coding for survival of motor neuron 1 protein may result in SPINAL MUSCULAR ATROPHIES OF CHILDHOOD. (harvard.edu)
Survival Motor Neuron Gene Copy Number Analysis by Exome Sequencing: Assisting Spinal Muscular Atrophy Diagnosis and Carrier Screening. (harvard.edu)
the invention also provides non-human animals and cells comprising a transgene encoding an APP comprising the Swedish mutation and further comprising functionally disrupted endogenous APP gene loci, transgenes and targeting constructs used to produce such transgenic cells and animals, transgenes encoding human Swedish mutation APP polypeptide sequences, and methods for using the transgenic animals in pharmaceutical screening and as commercial research animals for modeling neurodegenerative diseases (e.g. (justia.com)
amyloid peptide, a major constituent of the amyloid plaque, can result from mutations in the gene encoding amyloid precursor protein, a protein which when normally processed will not produce the .beta. (justia.com)
[ 4 ] The genetic defect appears to be a region of the gene encoding the KRT14 nonhelical head (E1/V1) domain located between the microsatellite markers D17S798 and D17S957, which are separated by approximately 26.97 cM. (medscape.com)
The PAX5 gene encodes for the B-cell-specific activator protein (BSAP), but PAX5 is the more commonly used term in diagnostic pathology literature. (roche.com)
In this review, we discuss considerations of the study design for each data feature, the limitations in gene and protein abundance and their rate of expression, the current data integration methods, and microbiome influences on gene and protein expression. (rsc.org)
Mutations in the gene for the antennapedia homeodomain protein are associated with the conversion of antenna to leg or leg to antenna DROSOPHILA. (lookformedical.com)
Homeodomain proteins are involved in the control of gene expression during morphogenesis and development (GENE EXPRESSION REGULATION, DEVELOPMENTAL). (lookformedical.com)
Methods】 An antennal binding protein gene was cloned by PCR, and the stage- and tissue-specific expressions of the gene were profiled using real-time quantitative PCR. (insect.org.cn)
Results】 The antennal binding protein gene cloned was named as PxylOBP31 (GenBank accession no. (insect.org.cn)
Background: This gene encodes a protein that is similar to the protein encoded by the breakpoint cluster region gene located on chromosome 22. (icbinhibitor.com)
The protein encoded by this gene contains a GTPase-activating protein domain, a domain found in members of the Rho family of GTP-binding proteins. (icbinhibitor.com)
Alternatively spliced transcript variants that encode different isoforms have been reported for this gene. (icbinhibitor.com)
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. (genetex.com)
GLUT1 is encoded by the Slc2a1 gene in human. (bicellscientific.com)
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to control CELL PROLIFERATION and APOPTOSIS. (bvsalud.org)
Next, the isolates were differentiated by sequencing a specific region of the gene encoding the enzyme glucosyltransferase B ( gtfB ). (bvsalud.org)
In addition, IGS sequencing (e.g., sequencing of intergenic regions between the 16S and 23S rRNA genes) has been used to taxonomy studies, while partial sequencing of the gene gtfB , which encodes the enzyme glucosyltransferase B, has been used to investigate enzymatic activity and virulence 11-12 . (bvsalud.org)

The specificity of interactions of these antisera with purified G protein β subunits indicates that the β 2 cDNA encodes the β 35 form of this polypeptide. (elsevierpure.com)
The human GH cDNA encodes a 217 amino acid (aa), and the first 26 aa is a signal peptide. (genscript.com)
Mouse IGSF4A cDNA encodes 445 amino acids including a signal peptide, three Ig-like domains (a V-type, a divergent C1-type and an I-type), a transmembrane domain and a cytoplasmic domain with protein 4.1 and PDZ domain binding sites. (rndsystems.com)

A wide list of potential new antimicrobial peptides was obtained by applying this method to about 4,000 human extracellular proteins. (unina.it)
Addition of D -alanine to TAs reduces the negative charge of the cell envelope thereby preventing cationic antimicrobial peptides (CAMPs) from reaching their target of action on the bacterial surface. (frontiersin.org)

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ABR. (icbinhibitor.com)

Here, we tested peptide-conjugated phosphorodiamidate morpholino oligomers (PPMOs), which inhibit translation of complementary mRNA from specific, essential genes in P. aeruginosa PPMOs targeted to acpP, lpxC, and rpsJ, inhibited P. aeruginosa growth in many clinical strains and activity of PPMOs could be enhanced 2- to 8-fold by the addition of polymyxin B nonapeptide at subinhibitory concentrations. (bvsalud.org)
In most gram-positive bacteria, this operon consists of five genes dltXABCD but the involvement of the first ORF ( dltX ) encoding a small protein of unknown function, has never been investigated. (frontiersin.org)
Our results suggest translation disrupting mechanisms relating uORF variation to reduced protein expression, and demonstrate that translation at uORFs is genetically constrained in 50% of human genes. (nature.com)
Specific uORFs are known to control protein expression by tuning translation rates of downstream protein-coding sequences, and potential uORFs have been identified in ~50% of all human protein-coding genes 1 , 2 . (nature.com)
The obvious next step is to integrate this information and learn how genes, proteins, and/or epigenetic factors influence the phenotype of a disease in context of the system. (rsc.org)
In addition to the host regulatory mechanisms response to disease, the microbiome can make changes to the expression of the host features such as their genes, proteins, and/or PTMs. (rsc.org)
Proteins encoded by homeobox genes (GENES, HOMEOBOX) that exhibit structural similarity to certain prokaryotic and eukaryotic DNA-binding proteins. (lookformedical.com)
Genes that encode highly conserved TRANSCRIPTION FACTORS that control positional identity of cells (BODY PATTERNING) and MORPHOGENESIS throughout development. (lookformedical.com)
The proteins encoded by homeobox genes are called HOMEODOMAIN PROTEINS. (lookformedical.com)
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. (rndsystems.com)
All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. (rndsystems.com)
Genes implicated in atopic dermatitis are those encoding epidermal and immunologic proteins. (msdmanuals.com)

Antisera were generated against synthetic peptides that correspond to amino acid sequences deduced from a cDNA (designated β 2 ) that encodes a second form of the β subunit of guanine nucleotide-binding regulatory proteins (G proteins). (elsevierpure.com)
Language": "en", "Country": "XG", "Code": "Intended Use" }, { "Name": "Background Information", "Value": "CONFIRM anti-PAX5 (SP34) Rabbit Monoclonal Primary Antibody (CONFIRM anti-PAX5 (SP34) antibody) is a rabbit monoclonal antibody directed against a synthetic peptide derived from the amino acid sequence within the C-terminus of human PAX5 protein. (roche.com)
Carrier-protein conjugated synthetic peptide surrounding phospho Thr421/Ser424 of human p70 S6K. (genetex.com)

Environmental sequences of ten novel plastid lineages and structural innovations in plastid proteins confirm that plastids in apicomplexans and their relatives are widespread and share a common, photosynthetic origin. (elifesciences.org)
In particular, upstream open reading frames (uORFs) are segments of 5′UTR mRNA sequences that can initiate and terminate translation upstream of protein-coding start codons. (nature.com)
As a result, we prepared a recombinant protein composed of the benzo[a]pyrene immunomimetic peptide and pIII-encoding sequences. (actanaturae.ru)

By sequencing complementary DNA strands that encoded for the hormone's mRNA, Land outlined the amino acid sequence of the precursor protein. (wikipedia.org)
In the liver of the c.3843−2A→G carrier, an apoB mRNA devoid of exon 25 was identified, predicted to encode a truncated peptide of 1260 amino acids. (bmj.com)
The analysis of minigene transcripts in COS-1 cells showed that the c.904+4A→G mutation caused the formation of an mRNA devoid of exon 8, predicted to encode a short apoB of 247 amino acids. (bmj.com)
this mRNA is predicted to encode a truncated protein of 1380 amino acids. (bmj.com)
Peptide-conjugated phosphorodiamidate morpholino oligomers are antisense molecules that inhibit bacterial mRNA translation. (bvsalud.org)
Biodistribution of onasemnogene abeparvovec DNA, mRNA and SMN protein in human tissue. (harvard.edu)
The biological system is complex with many regulatory features such as DNA, mRNA, proteins, metabolites, and epigenetic features such as DNA methylation and histone post-translational modifications (PTMs). (rsc.org)
The quintet of REV1 and POLZ in responsible pre-mRNA transcription ceramide( TLS) prevents that POLI destabilizes a numerous activity with REV1 and POLZ, extracellularly known for POLK and elucidated for vast Y factor cone peptides( Xie et al. (erik-mill.de)

In the ensuing decades, further technological and computational advances helped to refine these 'maps', with current estimates of the core mammalian mitochondrial proteome ranging from 1,000 to 1,500 proteins. (nature.com)
The invention provides transgenic non-human animals, such as transgenic rodents and transgenic non-human mammalian cells harboring a transgene encoding an APP polypeptide comprising the Swedish mutation. (justia.com)
The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. (genetex.com)

The demonstration that ribosomal peptide synthesis is a ribozyme-catalyzed reaction makes it almost certain that there was once an RNA World" (Orgel Leslie E. 2004). (bartleby.com)
Peptide epimerase-dehydratase complex responsible for biosynthesis of the linaridin class ribosomal peptides. (hokudai.ac.jp)

For this purpose, we synthesized carcinogen-protein conjugates and prepared mono- and polyclonal antibodies to benzo[a]pyrene. (actanaturae.ru)

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. (rndsystems.com)

Therefore, the lymphocytes are distinguished by their function and response to antigen, their cell membrane molecules and receptors, their types of secreted proteins, and their tissue location. (pediagenosis.com)
Glucose transporter 1 (or GLUT1), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a glucose transporter that permits the transport of glucose across the cell membrane. (bicellscientific.com)

The enzyme is capable of transferring the 4'-phosphopantetheine moiety of coenzyme A to a conserved serine residue in both the acyl carrier protein domain of the human cytosolic multifunctional fatty acid synthase and the acyl carrier protein associated independently with human mitochondria. (rhea-db.org)

[2] [3] The cells within the biofilm produce the EPS components, which are typically a polymeric conglomeration of extracellular polysaccharides , proteins , lipids and DNA . (wikipedia.org)
Notch receptors are single-pass transmembrane proteins composed of functional Notch extracellular domain (NECD), transmembrane (TM), and Notch intracellular domains (NICD). (frontiersin.org)

Mature CGRP1 and CGRP2 share significant sequence identity at the protein level differing by only 1-3 amino acid residues, depending on the species. (zeta-corp.com)
Normal processing of amyloid precursor protein involves proteolytic cleavage at a site between residues Lys.sup.16 and Leu.sup.17 (as numbered for the .nu.AP region where Asp.sup.597 is residue 1 in Kang et al. (justia.com)
Our results show that RumM catalyzed the introduction of dehydroamino acids into the core peptide of preRumA and subsequently conjugated the dehydrated residues with cysteine to generate thioether bridges. (tu-berlin.de)
Its ORF is 411 bp in length and encodes 136 amino acids, containing the six conserved cysteine residues of typical OBPs. (insect.org.cn)
Grisemycin, salinipeptin, and cypemycin belong to the linaridin class of ribosomally synthesized and posttranslationally modified peptides that contain multiple dehydrobutyrine and D-amino acid residues. (hokudai.ac.jp)

At the start codon, peptide synthesis initiates when the 40 s subunit acquires the 60 s subunit with other translation initiation factors. (nature.com)
It is also a vital medium in protein synthesis because it is the main molecules in DNA translation and transcription (wiki, translation) (wiki, transcription). (bartleby.com)
GH stimulates both the differentiation and proliferation of myoblasts, and also stimulates amino acid uptake and protein synthesis in muscle and other tissues. (genscript.com)

When Ca2+ channels are activated in response to a variety stimuli, a drastic increase in the [Ca2+]c is induced and the entered free Ca2+ binds to the sets of Ca2+-regulated proteins such as calmodulin and calcium dependent protein kinases to modify the activities or affinities of these proteins in binding to specific targets. (globalsciencebooks.info)
Language": "en", "Country": "XG", "Code": "Background Information" }, { "Name": "Principle", "Value": "CONFIRM anti-PAX5 (SP34) antibody binds to the PAX5 protein in formalin-fixed, paraffin-embedded (FFPE) tissue sections. (roche.com)
It is firstly activated into 20-hydroxyecdysone (20E) and then binds to its dimer-receptor composed of ecdysone receptor (EcR) and ultraspiracle protein (USP) to initiate 20E-induced cascade reaction. (insect.org.cn)
Biotinylated Recombinant Human FGFR2 alpha (IIIb) Fc Chimera Avi-tag (Catalog # AVI663) binds Recombinant Human FGF acidic/FGF1 (aa 16-155) Protein (Catalog # 232-FA ) with an ED 50 of 0.0500-0.500 μg/mL. (rndsystems.com)

POLK and POLZ have in the receptor of proteins reused multiple to such anions by POLK. (erik-mill.de)

Bak BH3 peptides antagonize Bcl-xL function and induce apoptosis through cytochrome c-independent activation of caspases. (lookformedical.com)

Exon A encodes a putative signal peptide, the arginine vasopressin hormone, and the N terminus of the NP carrier protein. (wikipedia.org)
Exon B, which is separated from exon A with a 1 kilobase-long intron, encodes the conserved middle portion of NP. (wikipedia.org)
A 227 kilobase intron separates exon B from exon C, which encodes the final domain, including the C terminus of NP and the glycoprotein. (wikipedia.org)
Exon 1 contains a CAG trinucleotide repeat that encodes the amino acid glutamine, followed by another repeat that encodes proline. (jci.org)

HDPs are seen as true multifunctional peptides with activities as diverse as chemotaxis, inhibition of LPS-induced inflammation, modulation of leukocyte differentiation and promotion of wound healing. (unina.it)

Then the binding properties of the antennal binding protein to 39 ligand compounds were detected by fluorescence competitive binding assays. (insect.org.cn)
N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry. (hokudai.ac.jp)

The human enzyme, which is expressed mainly in the cytosolic compartment in a wide range of tissues, is a 329-residue, monomeric protein. (rhea-db.org)
Results here demonstrate that fusing a larger protein carrier to the N-terminus of the leader peptide does not necessarily obstruct in vivo processivity of the lanthionine-generating enzyme in modifying its substrate. (tu-berlin.de)

amyloid precursor protein occurs via cleavage by a putative ".alpha. (justia.com)

In this study, we amplified parts of the RumA biosynthesis operon from R. gnavus E1, encoding the linear precursor peptide (preRumA) and the lanthionine synthetase (RumM), and coexpressed them in the heterologous bacterial host E. coli. (tu-berlin.de)

AVP and other AVP-like peptides are found in mammals, as well as mollusks, arthropods, nematodes, and other invertebrate species. (wikipedia.org)
Proteins that originate from insect species belonging to the genus DROSOPHILA. (lookformedical.com)
The proteins from the most intensely studied species of Drosophila, DROSOPHILA MELANOGASTER, are the subject of much interest in the area of MORPHOGENESIS and development. (lookformedical.com)

The feeble phenotype was mapped to a mutation in Slc15a4, which encodes the peptide/histidine transporter 1 (PHT1) and has not previously been implicated in pDC function. (nih.gov)
The identification of the feeble mutation led to our subsequent observations that AP-3, as well as the BLOC-1 and BLOC-2 Hermansky-Pudlak syndrome proteins are essential for pDC signaling through TLR7 and TLR9. (nih.gov)
We predict that 10 million humans carry one non-working copy of NPR-B and among individuals who are less than the 1st centile in height, approximately 1-in-20 will be NPR2 mutation carriers. (childrenshospital.org)
Even though 10 million people are NPR2 mutation carriers, only 3500 persons in the entire world are affected with AMDM. (childrenshospital.org)
Mutation impacts the oligomeric state of your ZIP13 protein. (icbinhibitor.com)
Mutation affects the oligomeric state in the ZIP13 protein. (icbinhibitor.com)

Endogenous substances, usually proteins, which are effective in the initiation, stimulation, or termination of the genetic transcription process. (lookformedical.com)
Two recently identified exo-lytic N -acetylmuramidases (Tf_NamZ1 and Tf_NamZ2) specifically cleave the peptide-free, exogenous (nutrition source) PGN in the periplasm and release the MurNAc and disaccharide substrates for the transporters Tf_MurT and Tf_AmpG, respectively, whereas the peptide-containing, endogenous (the self-cell wall) PGN stays unattached. (karger.com)

In this study, we confirmed that both GrmH and GrmL, which were shown to constitute a protein complex by a co-purification experiment, were required to catalyze the dehydration, epimerization, and proteolytic cleavage of a precursor peptide GrmA by in vivo experiments. (hokudai.ac.jp)

The aggregation of both amyloid beta (Abeta) peptides extracellularly and Tau proteins intracellularly plays key roles in the pathological consequences of AD, which lead to cholinergic neurodegeneration and eventually death. (inra.fr)
Alzheimer's disease is characterized by the presence of numerous amyloid plaques and neurofibrillary tangles (highly insoluble protein aggregates) present in the brains of AD patients, particularly in those regions involved with memory and cognition. (justia.com)
amyloid peptide. (justia.com)
amyloid peptide within the precursor protein. (justia.com)
amyloid peptide appears to be toxic to brain neurons, and neuronal cell death is associated with the disease. (justia.com)
amyloid peptide (also referred to as A4, .beta.AP, A.beta. (justia.com)
amyloid precursor protein (.beta.APP), which is expressed in differently spliced forms of 695, 751, and 770 amino acids. (justia.com)
amyloid peptide sequence (Esch et al. (justia.com)
amyloid peptide, thus apparently precluding its formation. (justia.com)
1992) Science 255:728-730, prepared a series of deletion mutants of amyloid precursor protein and observed a single cleavage site within the .beta. (justia.com)

IGSF4A is a 75 kDa immunoglobulin superfamily protein that mediates calcium-independent adhesive interactions, either homophilic or heterophilic with CRTAM (class I-restricted T cell-associated molecule), Necl-1 (SynCAM3) or Nectin-3 (1 - 4). (rndsystems.com)

Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus. (lookformedical.com)

We designed a genetic screen to identify proteins required for the development and specialized function of pDCs. (nih.gov)
Recent multi-omics studies have revealed the heterogeneity and complexity of tumor features such as their genetic mutations, transcriptome, proteins, and signaling pathways. (rsc.org)
Several other genetic backgrounds result in enlargement of the haltere significantly beyond the normal range of haploinsufficient phenotypes, suggesting genetic variation in cofactors that mediate homeotic protein function. (lookformedical.com)
Delivering exogenous genetic materials encoding Notch into cells can reestablish downstream signaling and rescue cellular functions. (frontiersin.org)

Inactivation of TCF7L2 protein attained by removing the high-mobility group (HMG)-box DNA binding domain in mature adipocytes in vivo leads to whole-body glucose intolerance and hepatic insulin resistance. (medscape.com)

Using ELISA, we demonstrated that the recombinant protein specifically interacts with the anti-benzo[a]pyrene monoclonal antibody (mAB B2). (actanaturae.ru)

Familial hypobetalipoproteinaemia (FHBL) is a codominant disorder characterised by fatty liver and reduced plasma levels of low-density lipoprotein (LDL) and its protein constituent apolipoprotein B (apoB). (bmj.com)
Once optimized the production system, a broad characterization of two novel recombinant peptides, previously identified in human Apolipoprotein B (ApoB), was performed. (unina.it)

Their diverse functions are enabled by a sophisticated set of protein components encoded by the nuclear and mitochondrial genomes. (nature.com)
In this Roadmap, we propose a path forward for refining the mitochondrial protein map to enhance its discovery and therapeutic potential. (nature.com)
We discuss how emerging technologies can assist the detection of new mitochondrial proteins, reveal their patterns of expression across diverse tissues and cell types, and provide key information on proteoforms. (nature.com)
Fig. 1: Comparison of the three main mitochondrial protein compendia. (nature.com)
Fig. 2: Potential sources of new mitochondrial proteins. (nature.com)
Fig. 3: Examples of innovative uses of mitochondrial protein maps. (nature.com)
Fig. 4: Translational utility of the mitochondrial protein map. (nature.com)
Fig. 5: The future mitochondrial protein map. (nature.com)
Two‐dimensional electrophoresis of human placental mitochondria and protein identification by mass spectrometry: toward a human mitochondrial proteome. (nature.com)

This final stage of research began when Gainer and colleagues found a precursor protein to vasopressin in 1977. (wikipedia.org)
This normal pathway cleaves within the region of the precursor protein which corresponds to the .beta. (justia.com)

The structure of the protein was subsequently discovered by Land in 1982. (wikipedia.org)

We show that uORF variants introducing new stop codons, or strengthening existing stop codons, are under strong negative selection comparable to protein-coding missense variants. (nature.com)

Gao, B , Mumby, S & Gilman, AG 1987, ' The G protein β 2 complementary DNA encodes the β 35 subunit ', Journal of Biological Chemistry , vol. 262, no. 36, pp. 17254-17257. (elsevierpure.com)

The unique potential of RNA molecules to act both as information carrier and as catalyst forms the basis of the RNA world hypothesis. (bartleby.com)

As most humans are host to S. mutans but not all carriers manifest dental caries, it has been suggested that certain strains of S. mutans associated with SECC could be genetically different from strains found in caries-free individuals 7 . (bvsalud.org)

A SMN complex protein that is essential for the function of the SMN protein complex. (harvard.edu)
Furthermore, we demonstrated that GrmH/GrmL complex accepted salinipeptin and cypemycin precursor peptides, which possess three additional amino acids. (hokudai.ac.jp)
To be somatic nucleus nucleotide through coupled uracil kDa at such cancers, transporters serve a scaffold, replaced to as activation deficit( TLS), which translocates form protein to Get complex classes. (erik-mill.de)

The human 4'-phosphopantetheine transferase is also capable of phosphopantetheinylation of peptidyl carrier and acyl carrier proteins from prokaryotes. (rhea-db.org)
Many human proteins with functions not necessarily related to host defense behave as sources of HDPs. (unina.it)
In order to identify by a rational approach further human proteins carrying cryptic HDPs, we recently developed an in-silico screening method to localize antimicrobial regions hidden inside the primary structure of precursor proteins. (unina.it)
One of these HDPs has been identified in human 11-hydroxysteroid dehydrogenase-1 β-like, the other represents the first HDP from an archaeal protein, the transcription factor Stf76 encoded by the hybrid plasmid-virus pSSVx from Sulfolobus islandicus. (unina.it)
2 μg/lane of Biotinylated Recombinant Human FGFR2 alpha (IIIb) Fc Chimera Avi-tag Protein (Catalog # AVI663) was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by Coomassie® Blue staining, showing bands at 100-112 kDa and 200-220 kDa, respectively. (rndsystems.com)

Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Intended Use", "Value": "CONFIRM anti-PAX5 (SP34) Rabbit Monoclonal Primary Antibody is intended for laboratory use in the qualitative immunohistochemical detection of PAX5 by light microscopy in sections of formalin-fixed, paraffin-embedded tissue stained on a BenchMark IHC/ISH instrument. (roche.com)
Western blot analysis of HD brain tissue shows full-length huntingtin protein in the nuclear fraction as well as abundant immunopositive bands at lower molecular weight, suggesting proteolytic products in the nucleus. (jci.org)
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. (rndsystems.com)
The archived repair recessive, inactivates the highest terminal of homocysteine cilium placenta throughout the tissue-localized protein. (erik-mill.de)

Scientists have been able to identify these specific proteins and correlate them with a specific cellular function. (pediagenosis.com)
Whole blood survival motor neuron protein levels correlate with severity of denervation in spinal muscular atrophy. (harvard.edu)

Functional studies in mice determined that this protein plays a role in vestibular morphogenesis, suggesting that Rho-related GTPases help coordinate motor skills and balance. (icbinhibitor.com)

The main aim of this PhD project was the identification of interesting potential HDPs, to develop novel bioactive peptides. (unina.it)

Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Content", "Value": "CONFIRM anti-PAX5 (SP34) antibody contains sufficient reagent for 50 tests. (roche.com)
The antibody is diluted in Tris-HCI with carrier protein, and 0.10% ProClin 300, a preservative. (roche.com)
p70 S6K (phospho Thr421/Ser424) antibody [HL5] detects p70 S6K (phospho Thr421/Ser424) protein at cytoplasm by immunohistochemical analysis in the presence of control peptide (left) or antigen-specific peptide (right). (genetex.com)

The signal peptide consists of 21 amino acids in the N terminus. (insect.org.cn)

NPR-B is activated by a small protein called CNP (C-type natriuretic peptide) and it, in turn, activates other proteins including PRGK2 (cyclic GMP dependent protein kinase 2). (childrenshospital.org)

Anatomy11

Organisms14

Diseases6

Chemicals and Drugs124

Analytical, Diagnostic and Therapeutic Techniques and Equipment42

Phenomena and Processes59

Disciplines and Occupations1

Technology, Industry, Agriculture1

Information Science4

Health Care2

Gene30

CDNA encodes3

Antimicrobial peptides2

Immunogen1

Genes12

Synthetic3

Sequences3

MRNA8

Mammalian3

Ribosomal2

Polyclonal1

Recombinant Proteins1

Cell Membrane2

Acyl carrier1

Extracellular2

Residues5

Synthesis3

Binds4

Receptor1

Apoptosis1

Exon4

Multifunctional1

Ligand2

Enzyme2

Putative1

Biosynthesis1

Species3

Mutation6

Endogenous2

Proteolytic cleavage1

Amyloid10

Immunoglobulin1

Nucleoproteins1

Genetic4

Vivo1

Monoclonal antibody1

ApoB2

Mitochondrial9

Precursor protein2

Subsequently1

Variants1

Complementary1

Molecules1

Genetically1

Complex3

Human5

Tissue4

Correlate2

Mice1

Identification1

Antibody3

Signal1

Dependent protein1