Progressive encephalomyelitisADEMRigidityAcuteOpsoclonus-myoclonus-ataxiExperimental autoimmune encephEncephalitisParaneoplasticReceptorsEncephalopathyNeuromyelitis opticaLimbMultiple sclerosisSeizuresPostinfectiousSensoryBrainViralChronicDaysRareTypeRigidity and myoclonusAcute Disseminated EnceSubacuteMyalgic encephalomyelitisSyndromeNeurologicalBehavioralClinicalExperimentalBrainSymptomsDiseases
Progressive encephalomyelitis11
- BACKGROUND: The syndrome of progressive encephalopathy with limb rigidity has been historically termed progressive encephalomyelitis with rigidity and myoclonus (PERM) or stiff-person syndrome plus. (ox.ac.uk)
- Redefining progressive encephalomyelitis with rigidity and myoclonus after the discovery of antibodies to glycine receptors. (ox.ac.uk)
- RECENT FINDINGS: Since the initial description in 2008 of antibodies to glycine receptors (GlyR-Abs) in a patient with progressive encephalomyelitis with rigidity and myoclonus (PERM), these antibodies have been found in PERM and in some patients with a variety of stiff person spectrum (SPS) or related disorders. (ox.ac.uk)
- Progressive encephalomyelitis with rigidity and myoclonus (PERM) - A kind of stiff person syndrome. (wikipedia.org)
- Anti-GlyR autoantibodies are associated with progressive encephalomyelitis with rigidity and myoclonus or stiff person syndrome. (uni-wuerzburg.de)
- Stiff-person spectrum disorders encompass classical stiff-person syndrome, partial/focal stiff-person forms such as stiff-limb and stiff-trunk, pure cerebellar ataxia, and a severe encephalomyelitic form referred to as progressive encephalomyelitis with rigidity and myoclonus (PERM). (arupconsult.com)
- SPS spectrum phenotypes included progressive encephalomyelitis with rigidity and myoclonus (PERM) (8), classic SPS (5), stiff limb (5), stiff trunk (1), and isolated exaggerated startle (hyperekplexia, 1). (neurology.org)
- Therapeutic considerations in a case of progressive encephalomyelitis with rigidity and myoclonus. (yalemedicine.org)
- Gluck L, Hernandez AL, Wesley SF, Fulbright RK, Longbrake EE , Stathopoulos P. Therapeutic considerations in a case of progressive encephalomyelitis with rigidity and myoclonus. (yalemedicine.org)
- In addition to classic SMS, there is also stiff leg syndrome (SLS) with stiffening of the leg muscles, progressive encephalomyelitis with rigidity and myoclonus (PERM) and paraneoplastic SMS. (medicinelearners.com)
- There are also disease developments in which SLS progresses to SMS and finally to progressive encephalomyelitis. (medicinelearners.com)
ADEM3
- two with acute disseminated encephalomyelitis (ADEM), two with ON, one with transverse myelitis (TM) and two with clinically isolated syndrome (CIS). (bmj.com)
- She has expertise in assessing children and adolescents with childhood cancer as well as neuro-immunological disorders, including opsoclonus-myoclonus-ataxia syndrome ("dancing eyes syndrome"), central nervous system vasculitis, Hashimoto's encephalopathy, lupus, auto-immune encephalitis, multiple sclerosis (MS), acute disseminated encephalomyelitis (ADEM), and acute transverse myelitis (ATM), and optic neuritis. (nesca-newton.com)
- Acute disseminated encephalomyelitis (ADEM) is often treated with high-dose intravenous corticosteroids, to which it appears to be responsive. (medscape.com)
Rigidity1
- These serum and cerebrospinal fluid (CSF) autoimmune stiff-person disorders panels can be used for the evaluation of patients with stiffness, spasms, hyperekplexia, limb rigidity, myoclonus, or limb dystonia in the presence or absence of encephalopathy. (arupconsult.com)
Acute2
- Various types of encephalomyelitis include: Acute disseminated encephalomyelitis or postinfectious encephalomyelitis, a demyelinating disease of the brain and spinal cord, possibly triggered by viral infection. (wikipedia.org)
- Acute disseminated encephalomyelitis at NIH's Office of Rare Diseases Acute Disseminated Encephalomyelitis Information Page at NINDS Pröbstel AK et al. (wikipedia.org)
Opsoclonus-myoclonus-ataxi1
- Diagnosis and Management of Opsoclonus-Myoclonus-Ataxia Syndrome in Children: An International Perspective. (nih.gov)
Experimental autoimmune enceph3
- Experimental autoimmune encephalomyelitis (EAE), an animal model of brain inflammation. (wikipedia.org)
- Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM-1. (2medicalcare.com)
- To investigate the therapeutic efficacy, pharmacokinetics, and toxicity profile of novel drug treatments using the Experimental Autoimmune Encephalomyelitis (EAE) mouse model, Cuprizone mouse model, and in-vitro models. (edu.au)
Encephalitis1
- Most patients (28 cases, 90.3%) had encephalitis with two and one cases of myelitis and encephalomyelitis respectively. (theupperroomsite.com)
Paraneoplastic1
- Keratocytes how much kratom to get high paraneoplastic encephalomyelitis url 30 servings of science will have a stupefying xl 40 mg visa. (banktech.cz)
Receptors1
- RESULTS: Serum antibodies to both NMDA receptors (NMDAR) and glycine receptors (GlyR) were detected postmortem, and examination of the brain confirmed an autoimmune encephalomyelitis, with particular involvement of hippocampal pyramidal and cerebellar Purkinje cells and relative sparing of the neocortex. (ox.ac.uk)
Encephalopathy1
- Patients with PERM exhibit a more severe form that also includes dysautonomia, encephalopathy (often with seizures), and myoclonus (muscle jerking). (arupconsult.com)
Neuromyelitis optica1
- AntiMOG associated encephalomyelitis, one of the underlying conditions for the phenotype neuromyelitis optica and in general all the spectrum of MOG autoantibody-associated demyelinating diseases. (wikipedia.org)
Limb1
- Myoclonus describes lightening-like limb movements or limb jerks, that can also be more tremulous. (osmosis.org)
Multiple sclerosis1
- Encephalomyelitis disseminata, a synonym for multiple sclerosis. (wikipedia.org)
Seizures2
- Among the nine patients with abnormal movements, five experienced chorea/dyskinesia (all experienced anti-NMDAr with one patient also presented with catatonia), two experienced faciobrachial dystonic seizures (both experienced anti-LGI1), one experienced stiff-person syndrome (anti-AMPAr-2), and one experienced myoclonus (anti-GABAr). (theupperroomsite.com)
- In patients with a hereditary seizure disorder, Progressive Myoclonus Epilepsy of the Unverricht Lundborg Type (PME-UL), characterized by myoclonus, generalized and absence seizures and deterioration in mental function, we found increased activity of the antioxidant enzyme extracellular superoxide dismutase (EC-SOD, SOD3)4-5. (internaf.org)
Postinfectious1
- Similar phenomena occur in other postinfectious diseases, such as Guillain-Barré syndrome or opsoclonus-myoclonus. (medscape.com)
Sensory1
- and a sarcoidosis-like syndrome with mediastinal lymph nodes and central nervous system (CNS) involvement (ie, dementia, sensory and motor deficits, ophthalmoplegia, myoclonus, stroke and hypothalamic damage with dysautonomia, emotional impairment, endocrinopathy). (medscape.com)
Brain1
- Encephalomyelitis is inflammation of the brain and spinal cord. (wikipedia.org)
Viral1
- Opsoclonus myoclonus may occur in association with tumors or viral infections. (vaccineinjuryhelpcenter.com)
Chronic1
- Chronic fatigue syndrome, sometimes called myalgic encephalomyelitis. (wikipedia.org)
Days1
- Improvement with NAC has included long periods of decreased myoclonus in the least affected patient such that she has been able to walk unaided for several days at a time. (internaf.org)
Rare1
- Opsoclonus- myoclonus syndrome (OMS) is a rare condition, characterized by rapid, uncontrolled eye movements (opsoclonus) and sudden twitching or jerking of muscles (myoclonus). (osmosis.org)
Type1
- AIDS-related encephalomyelitis, caused by opportunistic Human T-lymphotropic virus type III (HTLV-III) infection. (wikipedia.org)
Rigidity and myoclonus6
- Supranuclear gaze palsy in glycine receptor antibody-positive progressive encephalomyelitis with rigidity and myoclonus. (nih.gov)
- Glycine receptor antibodies and progressive encephalomyelitis with rigidity and myoclonus with predominant motor neuron degeneration--Expanding the clinical spectrum. (nih.gov)
- Redefining progressive encephalomyelitis with rigidity and myoclonus after the discovery of antibodies to glycine receptors. (nih.gov)
- Progressive encephalomyelitis with rigidity and myoclonus (PERM) - A kind of stiff person syndrome. (wikipedia.org)
- 9. Anti-glutamic acid decarboxylase (GAD) positive cerebellar Ataxia with transitioning to progressive encephalomyelitis with rigidity and myoclonus (PERM), responsive to immunotherapy: A case report and review of literature. (nih.gov)
- A diagnosis of progressive encephalomyelitis with rigidity and myoclonus (PERM) was established. (neurology.org)
Acute Disseminated Ence6
- Various types of encephalomyelitis include: Acute disseminated encephalomyelitis or postinfectious encephalomyelitis, a demyelinating disease of the brain and spinal cord, possibly triggered by viral infection. (wikipedia.org)
- Acute disseminated encephalomyelitis at NIH's Office of Rare Diseases Acute Disseminated Encephalomyelitis Information Page at NINDS Pröbstel AK et al. (wikipedia.org)
- Acute disseminated encephalomyelitis (ADEM) is often treated with high-dose intravenous corticosteroids, to which it appears to be responsive. (medscape.com)
- When the inflammation affects multiple areas within the brain it is called acute disseminated encephalomyelitis. (nih.gov)
- The Pediatric Multiple Sclerosis and Related Disorders Program cares for children and teens with MS , acute disseminated encephalomyelitis , acute transverse myelitis , and optic neuritis . (childrenshospital.org)
- Acute disseminated encephalomyelitis adem is an immunemediated inflammatory demyelinating condition that predominately affects the white matter of the brain and spinal cord. (web.app)
Subacute1
- Subacute necrotizing encephalomyelitis in the basal ganglia, brain stem, thalamus and posterior column of the spinal cord. (pathologycenter.jp)
Myalgic encephalomyelitis1
- Chronic fatigue syndrome, sometimes called myalgic encephalomyelitis. (wikipedia.org)
Syndrome3
- Opsoclonus- myoclonus syndrome is also called OMS or dancing eyes-dancing feet syndrome. (osmosis.org)
- Opsoclonus- myoclonus syndrome (OMS) is a rare condition, characterized by rapid, uncontrolled eye movements (opsoclonus) and sudden twitching or jerking of muscles (myoclonus). (osmosis.org)
- The condition may occur sporadically, follow an infection or vaccination, or present as a paraneoplastic syndrome (see also ENCEPHALOMYELITIS, ACUTE DISSEMINATED). (childrensmercy.org)
Neurological1
- Histopathologically, SSPE shows the same changes seen in other chronic viral encephalitis cases (eg Neurological complications of HIV ) and post-infectious encephalomyelitis. (physio-pedia.com)
Behavioral1
- Behavioral abnormalities, myoclonus , dementia , visual problems, and pyramidal and extrapyramidal symptoms are common in patients. (physio-pedia.com)
Clinical1
- Histopathology and clinical course of MOG-antibody-associated encephalomyelitis. (wikipedia.org)
Experimental2
- Experimental autoimmune encephalomyelitis (EAE), an animal model of brain inflammation. (wikipedia.org)
- The biological activity of glatiramer acetate is determined by its ability to block the induction of experimental autoimmune encephalomyelitis (EAE) in mice. (rxlist.com)
Brain1
- Encephalomyelitis is inflammation of the brain and spinal cord. (wikipedia.org)
Symptoms1
- The diagnosis of OMS is also often based on symptoms like opsoclonus and myoclonus which can appear abruptly, progressing over days to weeks. (osmosis.org)
Diseases1
- AntiMOG associated encephalomyelitis, one of the underlying conditions for the phenotype neuromyelitis optica and in general all the spectrum of MOG autoantibody-associated demyelinating diseases. (wikipedia.org)