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Virus AssemblyCapsidRNA, ViralGenome, ViralAvihepadnavirusVirus ReplicationVirionCapsid ProteinsNucleocapsidGene Products, polNucleocapsid ProteinsMolecular Sequence DataGenes, gagGene Products, gagHepatitis B Virus, DuckBase SequenceNucleic Acid ConformationDNA, ViralViral ProteinsCell LineViral Core ProteinsHepatitis B virus5' Untranslated RegionsRNA, SatelliteBromovirusTymovirusGene Expression Regulation, ViralHelper Virusesgag Gene Products, Human Immunodeficiency VirusPoliovirusGenetic VectorsHIV-1ClosterovirusHIV-2RepliconMutationDefective VirusesSequence DeletionGenes, ViralRNA-Directed DNA PolymeraseReverse TranscriptionVesiculovirusViral Structural Proteinsrev Gene Products, Human Immunodeficiency VirusPlasmidsFusion Proteins, gag-polMutagenesisvif Gene Products, Human Immunodeficiency VirusParvoviridaeCytidine DeaminaseSpumavirusMinute virus of miceAmino Acid SequenceTransfectionCercopithecus aethiopsTobaccoLevivirusNucleoproteinsLuteovirusPlant VirusesOrthobunyavirusHeLa CellsDNA PackagingGenetic Complementation TestRNA SplicingHepatitis B Core AntigensRibonucleasesMorphogenesisLeukemia Virus, MurineAlfalfa mosaic virusPlants, ToxicBunyamwera virusBinding SitesSindbis VirusPotexvirusProtoplastsPicornaviridaeVero CellsDNA ReplicationMutagenesis, Site-DirectedMoloney murine leukemia virusInverted Repeat SequencesLeukemia Virus, BovineGene Products, vifImmunodeficiency Virus, FelineDNA PrimersProtein PrecursorsRecombination, GeneticDimerizationProtein BindingOpen Reading FramesTranscription, GeneticRetroviridaeGene DeletionMutant ProteinsCucumovirusAmino Acid SubstitutionRNA-Binding ProteinsHordeumStructure-Activity Relationship
GenomeCore encapsidation signalHeterologousGenesProteinParticlesHepatitisProteinsMutationVector
Genome10
  • The Gammaretrovirus core encapsidation signal is an RNA element known to be essential for stable dimerisation and efficient genome packaging during virus assembly. (wikipedia.org)
  • Dimerisation of the viral RNA genomes is proposed to act as an RNA conformational switch which exposes conserved UCUG elements and enables efficient genome encapsidation. (wikipedia.org)
  • Many lentiviral vector genomes used for gene therapy are derived from HIV-1 and contain sequences required for genome expression, encapsidation and reverse transcription. (researchsquare.com)
  • The plasmid encoding the vector genome contained all of the signals necessary for its transcription, dimerization, encapsidation, reverse transcription and integration. (researchsquare.com)
  • The nucleocapsid (NC) protein NCp7 of human immunodeficiency virus type 1 (HIV-1) is important for encapsidation of the virus genome, RNA dimerization, and primer tRNA annealing in vitro. (nih.gov)
  • The C proteins is vital in encapsidation from the viral genome. (liveconscience.com)
  • Another important funtion of nucleocapsid protein is the encapsidation of viral genome. (leadgenebio.com)
  • The plant virus genome codes for proteins essential for their replication, cell-to-cell movement, and encapsidation. (iasexamportal.com)
  • We are currently using genetic, biochemical, and imaging approaches to study the interactions between viral Gag protein and full-length RNA that lead to the encapsidation of the viral genome during virus assembly. (nih.gov)
  • When compared to AAV2, AAV4 may be better suited as a vector due to its larger size -- which permits efficient encapsidation of a larger recombinant genome -- and its greater buoyant density -- which allows for easier separation of AAV4 from contaminating helper virus. (nih.gov)
Core encapsidation signal1
  • Whereas the core encapsidation signal is composed of 110 nt partially overlapping the gag start codon it is known that Gracillin sequences up- and downstream of this sequence also influence the encapsidation efficiency. (emlinhibitor.com)
Heterologous2
  • The HIV-1 Rev/RRE system is required for HIV-1 5′ UTR cis elements to augment encapsidation of heterologous RNA into HIV-1 viral particles. (unc.edu)
  • Heterologous encapsidation of PSTVd in particles of PLRV has been reported and may explain the observed insect transmission. (croptrust.org)
Genes1
  • 7. Encapsidation and transduction of cellular genes by retroviruses. (nih.gov)
Protein5
  • Role of Sindbis Virus Capsid Protein Region Ii in Nucleocapsid Core Assembly and Encapsidation of Genomic Rna. (purdue.edu)
  • Matrix protein (M1) of Influenza virus is a bifunctional membrane/RNA-binding protein that mediates the encapsidation of RNA-nucleoprotein cores into the membrane envelope. (embl-heidelberg.de)
  • and help to spatially segregate the viral RNA genome's competing functions as an mRNA for viral protein synthesis, a template for viral RNA synthesis, and a substrate for encapsidation. (elifesciences.org)
  • It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. (nih.gov)
  • Encapsidation of the genomic RNA (gRNA) of human immunodeficiency virus type 1 (HIV-1) is mediated by a specific interaction between the viral Gag protein and an RNA structure in the 59 untranslated region (59UTR) called encapsidation signal or Psi (Y). This association leads to incorporation of gRNA dimers into Gag/GagPol particles. (emlinhibitor.com)
Particles1
  • Evidence for heterogeneous encapsidation of potato spindle tuber viroid in particles of potato leafroll virus. (croptrust.org)
Hepatitis1
Proteins1
  • caption id="attachment_414" align="alignright" width="300" caption="Attendees listen to Robijn Bruinsma, University of California, Los Angeles, give his talk entitled: Encapsidation of Single-stranded RNA by Viral Proteins"][/caption] The Dynamic DNA Packaging Across Kingdoms: Chromatin & Beyond meeting, at Asilomar Conference Grounds on the beautiful shores of the Pacific, was held successfully in early July. (biophysics.org)
Mutation2
  • Contrarily, 3A mutation was reported to suppress pgRNA encapsidation. (nih.gov)
  • Furthermore, reduction of virion-associated gRNA levels by targeted deletions in the encapsidation signal or get 3PO mutation of Gag is accompanied by an increased amount of encapsidated spliced RNAs [8,9]. (emlinhibitor.com)
Vector1
  • Additional evidence for packaging of spliced RNAs was obtained when reverse transcribed cDNA corresponding to spliced viral RNAsRev-Stimulated Encapsidation of Spliced Vector RNAwas detected in HIV-1 infected cells [10,11]. (emlinhibitor.com)