• Measurements
  • Measurements of enantioselectivity at different water-activity values and temperatures showed that the water molecule had a high affinity for the stereospecificity pocket of the active site with a binding energy of 9 kJ mol(-1), and that it lost all its degrees of rotation, corresponding to an entropic energy of 37 Jmol(-1)K(-1). (diva-portal.org)
  • ligand
  • The extension of these findings subsequently led us to discover that an allylic zinc reagent bearing an anionic bis-oxazoline ligand takes place with excellent enantioselectivity (eqn. 2). (ic.ac.uk)
  • Addition of prenylzinc reagent to CPA 3 also proceeded in the presence of a ligand 2a with exclusive S E 'selectivity to give allylation product 5 in 90% yield with high enantioselectivity (93% ee). (ic.ac.uk)
  • Enantioselective allylation and prenylation of 3 in the presence of the anionic ligand 2b afforded allylzincation product 7 and 8 in good yield with comparable enantioselectivity to those of ligand 2a (eqn. 3). (ic.ac.uk)
  • effect
  • Tyrrell, E , Tesfa, KH , Mann, A and Singh, K (2007) Enantioselective alkynylation reactions to substituted benzaldehyde and salicylaldehyde derivatives: The effect of substituents upon the efficiency and enantioselectivity. (kingston.ac.uk)