• Bleasel MD, Peterson GM (2020) Emetine, ipecac, ipecac alkaloids and analogues as potential antiviral agents for coronaviruses. (vegetosindia.org)
  • A. M. A., 1914, 62, 501) showed that an infusion of ipecac representing one part of the drug in ten thousand destroyed the viability of the Entameba, and that the alkaloid emetine in a one to one-hundred-thousand solution had the same effect. (drugstoremuseum.org)
  • While this is a limited-use drug and most of the data are from the older literature, the basic ingredient in ipecac is emetine hydrochloride, which is used off label to induce vomiting in patients with anorexia nervosa. (entokey.com)
  • Ipecacuanha root gives Emetine, used to induce vomiting as in accidental poisoning. (howmed.net)
  • A toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. (harvard.edu)
  • Emetine hydrochloride is highly toxic when inadvertent direct ocular exposure occurs. (entokey.com)
  • The alkaloid conessine is used as a therapeutic drug for the treatment of dysentery and helminthic disorders. (sarkarhomoeo.com)
  • In chronic amoebiasis, Bi-iodide compound of total alkaloids, given orally, compare favorably with emetine Bi-iodide. (sarkarhomoeo.com)
  • Simon (J. A. M. A., 1918, 71, 2042) maintains that the whole drug administered by mouth gives better results than the subcu-taneous injection of the- alkaloid, especially in the chronic cases where the ameba has become encysted. (drugstoremuseum.org)
  • T., 1923, 21, 1) have found that both of these alkaloids have a direct stimu-lant action upon the vomiting center in the medulla. (drugstoremuseum.org)
  • i grain).065 g«fluideztractum cannabis indicae (u.pellotina, buy cheap tapentadol tablets alkaloid found in a mexican cactus, anhaloniiun lewiniiwhich is prepared by the purchase tapentadol online canada natives in the form of an intoxicant beverage calledmescale.lactucaritun (u.), concrete, milky exudate of lactuca virosa orlettuce. (avclark.com)
  • Ivy leaf has been found to contain 5-8% saponins (a chemical compound) and a low content of emetine (an alkaloid) - combined, these have the effect of helping thin, loosen and clear mucus from the chest. (humancarelabs.com)
  • It resembles emetine in its action, is a pale-yellow or white powder of bitter and acrid taste, more soluble in water than emetine, insoluble in ether, quite soluble in alcohol, and forming an insoluble compound with tannin solution. (henriettes-herb.com)
  • Alkaloids: biochemistry, ecology, and medicinal applications / edited by Margaret F. Roberts and Michael Wink. (wikipedia.org)
  • 1.Introduction 2.Classifications 3.Properties of alkaloids 4.Applications 5. (slideshare.net)
  • The Pioneer Enterprises and associated group of companies have modern manufacturing plants that produce a novel range of Phytochemicals and Alkaloids to the specifications and satisfaction of its customers. (pioneerherbal.com)
  • The ring structure is characteristic of the group of opium alkaloids such as papaverine. (jefferson.edu)
  • When injected subcutaneously or intravenously in large dose, however, the alkaloids act as depressants to the motor side of the spinal cord and probably also to the respiratory center. (drugstoremuseum.org)
  • This technology includes the use of two related compounds, Emetine and Cephaeline, as a potent inhibitor of the Zika virus (ZIKV). (nih.gov)
  • Emetine and it's analog Cephaeline were identified in a high-throughput assay aimed at identifying anti-ZIKV compounds. (nih.gov)
  • Both Emetine and Cephaeline are potent inhibitors of ZIKV infection in cell culture, and Emeline is a potent inhibitor of ZIKV infection in a live mouse model. (nih.gov)
  • This is the first report of Emetine or Cephaeline as antiviral compounds in ZIKV infection. (nih.gov)
  • Ipecacuanha contains the alkaloids emetine (methylcephaeline) and cephaeline. (wikipedia.org)
  • 0.031 The alkaloids present (cephaeline and emetine) indicated the? (nih.gov)
  • Other members of the ipecac class of alkaloids, e.g. emetine hydrochloride, were inactive against all of these enzymes, including HIV-1 RT. (neb.com)
  • These are alkaloids with a structure characterized by the presence of both an isoquinoline and a benzoquinolizidine nuclei. (drugbank.com)
  • Alkaloids found in OPIUM from PAPAVER and their derivatives that induce analgesic and narcotic effects by action upon OPIOID RECEPTORS. (jefferson.edu)
  • This compound belongs to the class of organic compounds known as emetine alkaloids. (drugbank.com)
  • 2005, Terpenoid tetrahydroisoquinoline alkaloids emetine, klugine, and isocephaeline inhibit the activation of hypoxia-inducible factor-1 in breast tumor cells. (wustl.edu)
  • Opiate Alkaloids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (jefferson.edu)
  • An example of emetic compound from the roots is emetine. (wikipedia.org)
  • Recent research has shown that the leaves contain the compound 'emetine', which is an amoebicidal alkaloid, and also triterpene saponins, which are effective against liver flukes, molluscs, internal parasites and fungal infections. (winksite.com)
  • For example, many years ago a plant chemical was discovered in a tropical plant, Cephaelis ipecacuanha, and the chemical was named emetine . (rain-tree.com)
  • We report the antiviral effect of remdesivir, lopinavir, homorringtonine, and emetine against SARS-CoV-2 virus in Vero E6 cells with the estimated 50% effective concentration at 23.15 μM, 26.63 μM, 2.55 μM and 0.46 μM, respectively. (nih.gov)
  • Drugs stimulating uterine smooth muscles, such as purgatives, anti-malarials, and ergot alkaloids, must be avoided during pregnancy. (studiousguy.com)
  • An indolizidine alkaloid from the plant Swainsona canescens that is a potent alpha-mannosidase inhibitor. (harvard.edu)
  • Alkaloids: biochemistry, ecology, and medicinal applications / edited by Margaret F. Roberts and Michael Wink. (wikipedia.org)
  • Many natural substances, such as various plant alkaloids, have been found to disrupt cellular function and are well-suited for various cancer treatments. (exactnewz.com)
  • Then a scientist was able to synthesize or copy this plant alkaloid into a chemical drug without using the original tree bark for manufacturing the drug. (rain-tree.com)
  • 9. The alkaloid emetine sensitizes ovarian carcinoma cells to cisplatin through downregulation of bcl-xL. (nih.gov)
  • Emetine inhibits protein synthesis in EUKARYOTIC CELLS but not PROKARYOTIC CELLS . (nih.gov)
  • Use of these alkaloids for the definition of this viral enzyme-specific topology may lead to the development of therapeutically useful chemotherapeutic agents. (neb.com)
  • While there has been some cardiotoxicity reported with high dosage of emetine, the effective IC50 observed in cell culture and mice is well below the toxic dosage. (nih.gov)
  • This graph shows the total number of publications written about "Opiate Alkaloids" by people in this website by year, and whether "Opiate Alkaloids" was a major or minor topic of these publications. (jefferson.edu)
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