AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaTechnology, Industry, AgricultureInformation ScienceNamed GroupsHealth CareGeographicals
AcinetobacterDrug Resistance, MicrobialAnti-Bacterial AgentsDrug Resistance, MultipleMicrobial Sensitivity TestsDrug Resistance, Multiple, BacterialCross InfectionElectrophoresis, Gel, Pulsed-FieldBacterial Typing TechniquesAcinetobacter InfectionsDNA, BacterialSequence Analysis, DNAbeta-LactamasesDrug Resistance, BacterialPseudomonas aeruginosaEscherichia coliSerotypingDNA FingerprintingStaphylococcal InfectionsDisease OutbreaksCarbapenemsStaphylococcus aureusPlasmidsGram-Negative Bacterial InfectionsIntegronsPseudomonas InfectionsStaphylococcus haemolyticusGram-Negative BacteriaGenes, BacterialStreptococcus pneumoniaeMultilocus Sequence TypingKlebsiella InfectionsKlebsiella pneumoniaeSpecies SpecificityMolecular EpidemiologyPolymerase Chain ReactionColistinGenotypeMolecular Sequence DataEnterococcus faeciumVirulencePenicillin ResistanceMethicillin ResistancePhenotypePhylogenyImipenemNatural SpringsBacterial ProteinsEnterobacteriaceae InfectionsBacteriophage TypingRNA, Ribosomal, 16SCiprofloxacinAmikacinCluster AnalysisAcinetobacter baumanniiMolecular TypingMice, Inbred StrainsConjugation, GeneticEscherichia coli InfectionsGram-Positive BacteriaGram-Positive Bacterial InfectionsDNA, RibosomalMutationR FactorsAnti-Infective AgentsStaphylococcusbeta-Lactam ResistanceStaphylococcus epidermidisFecesSalmonella InfectionsVirulence FactorsGenome, BacterialGentamicinsEnterococcusSalmonella Infections, AnimalPolymorphism, Restriction Fragment LengthAmino Acid SequenceAminoglycosidesDNA Transposable ElementsThienamycinsDisk Diffusion Antimicrobial TestsRibotypingAcetamidesSalmonella entericaOxazolidinonesFluoroquinolonesMethicillin-Resistant Staphylococcus aureusPolymyxin BChromosomes, BacterialCommunicable Diseases, EmergingEnterobacteriaceaeSalmonella typhimuriumColony Count, MicrobialErythromycinTrimethoprimTobramycinEnterococcus faecalisIntensive Care UnitsVancomycin ResistanceCoagulase
BacteriaMulti-resistantEscherichiaPneumoniaeAntimicrobial resistanceStaphylococcusMultidrug-resistantMicrobial strainsPseudomonasEnterobacterMRSAGenesSusceptibility testClinicalPathogensColiInhibitionVirulentPathogenicBacterial resistanceResistant to antibioticsAntimicrobialsSalmonellaInfectionsOccurrencePenicillinCharacterizationBaumanniiTuberculosisGenomeSpreadMethodsProteinConclusionTherapeuticExposureHealthcarePatientsAnimalMajorStudyBackgroundGlobalSelection
Bacteria13
  • The emergence of resistant strains of bacteria and the ensuing management challenges are compounded by the fact that the development of new antibiotics has decreased in recent years. (umf.org.nz)
  • Many of these studies also associate the emergence of bacteria from these ecosystems with resistance to antibiotics. (fortunejournals.com)
  • In the isolation of the strains, we used selective media for Gram-negative Bacteria MacConkey Agar (AM), supplemented with 32µg/ml cephalothin, 10U/ml penicillin and 2µg/ml clindamycin. (fortunejournals.com)
  • Interestingly, as a result, we found more than 20 colonies with distinct colors that grew even in the presence of different classes of antimicrobials, suggesting that they are colonies of multiresistant Gram-negative bacteria, since the MacConkey Agar medium is selective. (fortunejournals.com)
  • A study examining the biofilm-forming ability of multidrug-resistant A. baumannii strains recently isolated from a clinical sample indicated that all resistant bacteria exhibited higher biofilm-forming ability than the standard A. baumannii strain ATCC 19606 [ 11 ]. (ophrp.org)
  • Yet, less than 100 years after Alexander Fleming first discovered penicillin, the world is on the cusp of a post-antibiotic era, with multi-resistant strains of bacteria emerging at alarming rates all around the world. (proveg.com)
  • In this work, the inhibitory effect of apitoxin samples (n=3) on strains of multi-resistant bacteria Acinetobacter baumanii, Klebsiella pneumoniae, Enterococcus faecium and Staphylococcus aureus (n=20) was tested. (nsk.hr)
  • The emergence of antimicrobial resistance is a great challenge in preventing, controlling and treatment Gram-negative bacteria and has become a significant public health threat worldwide. (researchsquare.com)
  • The increase in circulating resistant strains of infectious bacteria make it difficult for the use of current available and recommended antimicrobial drugs (11). (researchsquare.com)
  • One strategy to fight multiresistant bacteria is to coordinate well-known drugs to a metal ion with antibacterial activity, resulting in a coordination compound that would have additive or synergic activity with the ligand. (fapesp.br)
  • Following the initial remarkable success of antibiotics, the emergence and spread of human pathogenic bacteria resistant to antibiotics has become a major phenomenon in the past fifty years. (europa.eu)
  • The emergence and spread of human pathogenic bacteria resistant to antibiotics has become a major problem in the past fifty years. (europa.eu)
  • Rational use of antibiotics and implementation of surveillance system for MDR bacteria must be implemented in order to limit the emergence and spread of MDR bacteria in Niger Republic. (bvsalud.org)
Multi-resistant4
  • However, the emergence and spread of hypervirulent and multi-resistant strains of this bacterium have recently extended its potential targets to people with no health problems. (krqe.com)
  • There is a growing concern on the emergence and re-emergence of drug-resistant pathogens such as multi-resistant bacterial strains. (microbiologyjournal.org)
  • 2010). Indeed, antibiotic therapy promotes the pressure to select multi-resistant strains. (internationalscholarsjournals.com)
  • Therefore, based on the current concern of antibiotic overuse in wound healing, the emergence of multi-resistant organisms and the decrease in newer antibiotics, AlpaWash is considered a prominent formulation to be employed in wound-healing applications. (blogspot.com)
Escherichia4
Pneumoniae5
  • forchildren0-2yearsofage.Lower-levelefflux[ mef (A)]- Resistance to macrolides in S. pneumoniae is medi- mediated macrolide resistance decreased in prevalence ated by 2 major mechanisms: target modification caused to50%,andhighlyresistant[ erm (B) + mef (A)] strains in- by a ribosomal methylase encoded by the erm (B) gene creasedto25%.Telithromycinandlevofloxacinsusceptibil- or drug efflux encoded by the mef (A) gene. (cdc.gov)
  • Recent studies in Europe and the United States 3 , 4 also revealed the existence of K. pneumoniae strains with an exceptionally high level of antimicrobial resistance, making them even more difficult to treat. (krqe.com)
  • This level of antimicrobial resistance in K. pneumoniae strains had never been observed before. (krqe.com)
  • 7 In tropical countries, there has been an emergence of Streptococcus pneumoniae that is resistant to penicillin, cefotaxime, and chloramphenicol. (jabfm.org)
  • Role of IncHI2 plasmids harbouring blaVIM-1, blaCTX-M-9, aac(6')-Ib and qnrA genes in the spread of pneumoniae multiresistant Enterobacter cloacae and Klebsiella strains in different units at Hospital Vall d'Hebron, Barcelona, Spain. (edu.iq)
Antimicrobial resistance2
  • What accelerates the emergence and spread of antimicrobial resistance? (paho.org)
  • Currently there are fewer antimicrobials available for treatment and prevention of some of bacterial infections (1).Antimicrobial resistance development in some of bacterial strains undermines empirical treatment regimens, thereby limiting choice of appropriate antibiotic (2).As this problem continues to grow, epidemiological surveillance is warranted to generate data that is reliable to understand the distribution of AMR among healthcare settings and geographical regions (3). (researchsquare.com)
Staphylococcus1
  • Objetivo: Describir las características epidemiológicas y clínicas de los niños con bacteriemia adquirida en la comunidad por Staphylococcus aureus y comparar las características de los pacientes con y sin shock séptico. (bvsalud.org)
Multidrug-resistant2
  • Using multidrug-resistant A. baumannii strains, an antibiotic susceptibility test was performed using the Gram-negative identification card of the Vitek 2 system (bioMérieux Inc., France), as well as an analysis of resistance genes, the effects of treatment with a light-emitting diode (LED) array using Radachlorin (RADA-PHARMA Co., Ltd., Russia), and transmission and scanning electron microscopy to confirm the biofilm-inhibitory effect of PDT. (ophrp.org)
  • This problem of multidrug-resistant organisms in developing countries can also directly affect and threaten more developed countries (such as the United States) because international travel, driven by globalized trade, allows for easier dissemination of these strains. (jabfm.org)
Microbial strains2
  • The extensive use of antibiotics to treat wound infection leads to emerging new microbial strains that are resistant to many antibiotics. (microbiologyjournal.org)
  • This in turn may result in the unintended exposure of both human and animal populations to these resistant microbial strains, independently of direct antimicrobial consumption. (bayind.de)
Pseudomonas3
  • Pseudomonas putida se ha considerado un patógeno de baja virulencia y sensible a múltiples antibióticos, pero en los últimos años han emergido cepas resistentes. (bvsalud.org)
  • Antibacterial honey (Medihoney): in vitro activity against clinical isolates of MRSA, VRE, and other multiresistant gram-negative organisms including Pseudomonas aeruginosa. (umf.org.nz)
  • Whole genome sequencing reveals the emergence of a Pseudomonas aeruginosa shared strain sub-lineage among patients treated within a single cystic fibrosis centre. (cdc.gov)
Enterobacter1
  • Prevalence and characterization of extended spectrum beta-lactamase-producing Enterobacter cloacae strains in Algeria. (ac.ir)
MRSA4
  • In 2006 in Marseille, France, we have detected an atypical MRSA strain with a specific antibiotic susceptibility profile and a unique growth phenotype. (biomedcentral.com)
  • Analysis of CF-Marseille shows a similar core genome to that of previously sequenced MRSA strains but with a different genomic organization due to the presence of specific mobile genetic elements i.e. a new SCCmec type IV mosaic cassette that has integrated the pUB110 plasmid, and a new phage closely related to phiETA3. (biomedcentral.com)
  • In conclusion, we demonstrated the emergence and spreading of a new isolate of MRSA in CF patients in Marseille, France, that has probably been selected in the airways by antibiotic pressure. (biomedcentral.com)
  • The emergence of well-adapted MRSA is worrying in such population chronically colonized and receiving many antibiotics and represents a model for emergence of uncontrollable super bugs in a specific niche. (biomedcentral.com)
Genes3
Susceptibility test1
Clinical1
  • Because of the clinical importance of the spread of such strain among CF patients we decided to sequence the genome of one representative isolate (strain CF-Marseille) to compare this to the published genome sequences. (biomedcentral.com)
Pathogens1
  • Multiresistant pathogens cause large increases in healthcare costs due to the need of more expensive drugs and a prolonged hospital stay. (paho.org)
Coli2
Inhibition3
  • The results showed that there is no significant difference in inhibition between different strains of the same species, as well as between the effectiveness of different samples of apitoxin. (nsk.hr)
  • An hmp -deficient strain showed a prolonged growth inhibition in response to DETA/NO compared to the wild type. (biomedcentral.com)
  • A range of 18-100% errors on the inhibition zone diameters of the reference strains were observed. (bvsalud.org)
Virulent2
  • Algo-Bio ® administration decreased virulent strains in piglet microbiota. (internationalscholarsjournals.com)
  • The emergence of highly virulent and antibiotic-resistant Salmonella has led to greater morbidity and mortality in humans, particularly in the last few decades. (proveg.com)
Pathogenic1
  • Findings of this study will enhance the future of the therapeutic strategies against the resistant pathogenic strains that cause wound infections. (microbiologyjournal.org)
Bacterial resistance1
  • The uncritical use of antibiotics has caused the global emergence of bacterial resistance to conventional antibiotics. (nsk.hr)
Resistant to antibiotics1
  • This pathology represents the first cause of treatment and preventive use of antibiotics in animal husbandry, leading to the emergence of enterobacteria resistant to antibiotics most commonly used (Dadié et al. (internationalscholarsjournals.com)
Antimicrobials2
  • 1 This situation prompts revisiting traditional approaches to infection management and use of those antimicrobials where the emergence of resistant strains has not been demonstrated and is highly unlikely to occur. (umf.org.nz)
  • Emergence of multidrug resistance in Enterobacteriaceae limits the selection of antimicrobials for treatment of infectious diseases. (biomedcentral.com)
Salmonella2
  • 8 A recent study links the emergence of human-adapted Salmonella to the introduction and intensification of animal farming. (proveg.com)
  • Case-control investigation of invasive Salmonella disease in Malawi reveals no evidence of environmental or animal transmission of invasive strains, and supports human to human transmission. (liverpool.ac.uk)
Infections1
  • Reports at the emergence and incidence of resistant bacterial infections in hospitals and groups bring up matters that we may well quickly now not be ready to depend upon antibiotics so as to keep an eye on infectious illnesses. (blodbad.net)
Occurrence1
  • Occurrence of toxin producing strains of Pasteurella multocida in different mammalian and avian species. (bisgaard.eu)
Penicillin1
  • 8 Neisseria gonorrhoeae has developed strains resistant to penicillin, sulfonamides, tetracyclines, and fluoroquinolones. (jabfm.org)
Characterization1
  • Phylogenetic characterization of norovirus strains detected from sporadic gastroenteritis in Seoul during 2014-2016. (cdc.gov)
Baumannii2
  • A class-D-type β-lactamase was found, and OXA-23 and OXA-51 were found in 100% of 15 A. baumannii strains. (ophrp.org)
  • Thus, CC92 A. baumannii carrying OXA-23 is a major drug-resistant strain spreading in China. (frontiersin.org)
Tuberculosis2
  • Although advances have been made in recent years for the treatment of tuberculosis (TB), huge challenges such as the emergence of resistant strains become distant the goals to achieve the eliminating the disease in the near future. (fapesp.br)
  • One of the reasons for the high mortality number caused by tuberculosis is the emergence of many new bacterial stains that are multiresistant to first line commercial drugs. (fapesp.br)
Genome1
  • Phylogenetic analyses using Complete Genome Hybridization and Multi Locus VNTR Assay showed that CF-Marseille was closely related to strain Mu50, representing vancomycin-resistant S. aureus . (biomedcentral.com)
Spread1
  • Many results drawn from previous studies of the effect of antibiotic use on emergence, selection and spread of AMR have lacked a holistic view combining all aspects into one study. (europa.eu)
Methods1
Protein2
  • Whole cell protein profiling of Actinobacillus -like strains classified as taxon 2 and taxon 3 according to Bisgaard. (bisgaard.eu)
  • nesto, settings are actively farmed as straining with Antibiotic iz, protein ligne, and hriscansku apologetics, though the pripadale is short-changed. (trapp-mg.de)
Conclusion1
Therapeutic1
  • The aim of this study is first to identify in Félix Guyon Hospital (Reunion Island) the emergent antibiotics resistance for enterobacteriaceae between 1997/1998 and 2006/2007 periods, at second, to update the prophylactic and therapeutic measures for handling the risk linked to multiresistant enterobacteriaceae in our hospital and third, to assess the risk in Reunion Island and especially at the community level. (univ-reunion.fr)
Exposure1
  • The pharmacodynamic study modelled the relationships between antibiotic exposure and AMR emergence over time for various classes of agents. (europa.eu)
Healthcare2
  • The media regularly reminds both the public and healthcare professionals of the dangers infection poses to good health, in particular the difficulties in successfully treating infection caused by multiresistant microorganisms. (umf.org.nz)
  • There is a host of communicable diseases that are associated with the consumption of animal-based products, creating additional risks for individual health and putting additional strain on healthcare systems. (proveg.com)
Patients2
  • The products were sequenced and the and the emergence of resistance to patients had lung congestion, burning nucleotide sequences and deduced- expanded-spectrum cephalosporins is upon urination and fever. (who.int)
  • Méthodes : Analyse de la sensibilité aux antibiotiques de 7814 souches d'entérobactéries isolées chez des patients hospitalisés au sein de prélèvements à visée diagnostique au cours des deux périodes considérées et mesure de la consommation en céphalosporine de 3e génération (C3G), imipénème (IMP) et fluoroquinolones (FQ). (univ-reunion.fr)
Animal1
  • A considerable number of multiresistant strains that have emerged in animal farming show resistance to a wide variety of antibiotics, constituting a significant food-safety hazard. (proveg.com)
Major1
  • Major and/or minor categorization (Sensitive S, Intermediate I and Resistance R) discrepancies were found at all the laboratories for either one or both reference strains. (bvsalud.org)
Study1
  • Carolina Duarte participated in all the stages of the un hospital pediátrico de tercer nivel en Colombia - 2016 study. (bvsalud.org)
Background1
  • This entire 2007 survey of recent plant breeding strains its background from the earliest experiments on the sunrise of the medical revolution within the 17th century to the current day and the life of excessive tech agribusiness. (blodbad.net)
Global1
  • There have been an increased number of global outbreaks where this strain of fungus was found. (wikipedia.org)
Selection1
  • To gain a handle on the factors that are propelling the problem of AMR, molecular and patient-level investigations are necessary to better elucidate the time-varying and heterogeneous role of antibiotic selection pressure on emergence and selection of AMR. (europa.eu)