Embryos at gastrulation mammalian embryos. Medical search. Frequent questions

During gastrulation of triploblastic animals, the three germinal layers that form are called the ectoderm, mesoderm, and endoderm. (wikipedia.org)
Furthermore, we use single-cell profiling to show that Tal1 -/- chimeric embryos display defects in early mesoderm diversification, and we thus demonstrate how combining temporal and transcriptional information can illuminate gene function. (nih.gov)
During gastrulation, three distinct layers of cells are formed in the embryo that will later give rise to all the body's major systems: the ectoderm will make the nervous system, mesoderm the muscles, and endoderm the gut. (scitechdaily.com)
In the mouse, it starts to form shortly after gastrulation, and is derived primarily from embryonic mesoderm. (ox.ac.uk)
About 21 days after the implantation of the embryo onto the uterus, the endoderm, mesoderm and ectoderm grow further and differentiate to form neutral tube and notocord, among other vital organs of the body. (brainyhomeworkhelp.com)
Dll1 expression in the paraxial mesoderm and nervous system is strikingly similar to the expression of mouse Notch1 during gastrulation and early organogenesis. (jax.org)
In our most recent work we have focused on the role of bone morphogenetic protein (BMP)-4 in the cell fate decision between endoderm and mesoderm, demonstrating the similarity of BMP-induced hESC and EpiSC differentiation to mesoderm induction during mouse gastrulation. (qscience.com)
Induction of three germ layers (ectoderm, mesoderm, and endoderm) and axis formation including the dorsoventral and anteroposterior posterior regions are major events during vertebrate embryo development. (molcells.org)
Here, we show that in Xenopus, Fry plays a role in morphogenetic processes during gastrulation, in addition to its previously described function in the regulation of dorsal mesoderm gene expression. (nature.com)
Loss of Fry function drastically affects the movement and morphological polarization of cells during gastrulation and disrupts dorsal mesoderm convergent extension, responsible for head-to-tail elongation. (nature.com)
At the beginning of Xenopus gastrulation, the presumptive anterior mesoderm cells located at the dorsal marginal zone (DMZ) roll inward at the midline of the blastopore lip in a process called involution. (nature.com)
Simultaneously, on the dorsal side of the embryo, axial and paraxial mesoderm tissues undergo convergent extension which elongates the anterior-posterior axis and aids blastopore closure. (nature.com)

Together, this comprehensive delineation of mammalian cell differentiation trajectories in vivo represents a baseline for understanding the effects of gene mutations during development, as well as a roadmap for the optimization of in vitro differentiation protocols for regenerative medicine. (nih.gov)
Researchers once thought high signal in one area of the embryo and low signal in another determined differentiation, but the Rice lab's experiments showed otherwise. (medicallyprime.com)
Recent advances have uncovered details of the molecular circuits that tightly control cell growth and differentiation in the mammalian embryo from the blastocyst stage, through the establishment of initial anterior-posterior polarity, to gastrulation, when the germ cells are set aside and the three primary germ layers are specified. (ox.ac.uk)
P53 depletion in naive hPSCs increased their contribution to mouse-human cross-species chimeric embryos upon priming and differentiation. (janelia.org)
Our research focuses on understanding how pluripotent mammalian stem cells maintain their undifferentiated state and undergo differentiation in culture - this reflecting my enduring interest in the emergence of diversity during mouse gastrulation. (qscience.com)

Moreover, the dynamic of H3K27me3 at PCH during in vitro conversion from naïve to primed pluripotent state and during ESCs derivation suggests that the mechanisms underlying the control of this histone mark at PCH are different in embryo and in vitro. (sciencegate.app)
Currently, the ability to culture in vitro totipotent cells possessing molecular and functional features like those of an early embryo in vivo has been a challenge. (sciencegate.app)
2- to 4-cell and morula- to blastocyst-stage mouse embryos were cultured for 1 h in tritiated leucine at two specific activities and their subsequent development followed in vitro and in vivo (after transfer to recipients), respectively. (sciencegate.app)
While early human embryos are inaccessible for research, in vitro model systems using pluripotent stem cells have provided critical insights into human PGC specification, which differs from that in mice. (elsevierpure.com)
Since then, Alejandro has been focusing on devising platforms for in vitro growth of mammalian embryos, harnessing these new platforms for studying the mechanisms regulating early mouse embryogenesis. (ivfmeeting.com)
A new technique that allows embryos to develop in vitro beyond the implantation stage (when the embryo would normally implant into the womb) has been developed by scientists at the University of Cambridge allowing them to analyse for the first time key stages of human embryo development up to 13 days after fertilisation. (futuristech.info)
Bioethicists from Case Western Reserve University School of Medicine and The Hastings Center, working with a research administrator at The Rockefeller University, are proposing a reexamination of an internationally recognized rule limiting in vitro research on human embryos to 14 days post-fertilization. (futuristech.info)
Here, we establish an in vitro system to culture human embryos through implantation stages in the absence of maternal tissues and reveal the key events of early human morphogenesis. (futuristech.info)
Ref: Self-organization of the in vitro attached human embryo. (futuristech.info)
Here we report the use of a novel in vitro system to study the post-implantation development of the human embryo. (futuristech.info)
We unveil the self-organizing abilities and autonomy of in vitro attached human embryos. (futuristech.info)
2019). Akin to the dynamic nutrient requirements of the developing embryo, discrete in vitro cell states have distinct metabolic profiles (Zhou et al. (conditionmed.org)
c) Developmental genes in man, in vitro fertilization and embryo transfer, cloning. (iaszoology.com)
Machine learning-assisted high-content analysis of pluripotent stem cell-derived embryos in vitro. (caltech.edu)

Here, he developed time-lapse microscopy approaches to study early post-implantation mouse embryos, with which he characterised the active migration of cells of the Anterior Visceral Endoderm, a process essential for the correct orientation of the anterior posterior axis of the embryo. (ox.ac.uk)
Dissection of Otx2 roles during gastrulation: requirement of Otx2 in the visceral endoderm for specification of anterior identity, and in the early neuroectoderm for maintenance of the anterior identity (forebrain and midbrain). (cnr.it)

Once implanted the embryo will continue its development through the next stages of gastrulation, neurulation, and organogenesis. (wikipedia.org)
The development of a zygote into a multicellular embryo proceeds through a series of recognizable stages, often divided into cleavage, blastula, gastrulation, and organogenesis. (wikipedia.org)
In mouse, gastrulation starts after a blastula implants into the uterine walls of the mother, and is immediately followed by development of different organ systems also knows as organogenesis. (brainyhomeworkhelp.com)
Dll1 is transiently expressed during gastrulation and early organogenesis, and in a tissue-restricted manner in adult animals. (jax.org)
Embryo model completes gastrulation to neurulation and organogenesis. (caltech.edu)
Acetyl CoA and total short chain CoA esters start to increase around midblastula transition (MBT) and continue to increase through stages of gastrulation, neurulation and early organogenesis. (irjs.info)

In the US, where a portion of the population is opposed to destruction of human embryos to obtain stem cells, what avenues are open to scientists for obtaining pluripotent cells that do not offend the moral sensibilities of a significant number of citizens? (asu.edu)
Across the animal kingdom, gastrulation represents a key developmental event during which embryonic pluripotent cells diversify into lineage-specific precursors that will generate the adult organism. (nih.gov)

lilli functions as a maternally provided pair-rule gene that is essential for proper cellularization, gastrulation and segmentation during embryogenesis. (sdbonline.org)
The heart is one of the first organs to develop during mammalian embryogenesis. (ox.ac.uk)
restorative research provides evidence for natural rejuvenation processes occurring at the epigenetic level during mammalian embryogenesis. (epigenie.com)
For example, the rejuvenation of the germline in mammalian offspring removes any deleterious aging-associated changes passed on by parents and returns epigenetic aging to " ground zero " during early embryogenesis to prevent accumulated damage from affecting future generations. (epigenie.com)
Fascinatingly, the young whippersnappers from the Gladyshev lab now reveal some fascinating insights into the dynamics and the mechanisms involved in the rejuvenation of DNA methylation profiles during the very early stages of mammalian embryogenesis. (epigenie.com)
Gastrulation is a key event in animal embryogenesis during which germ layer precursors are rearranged and the embryonic axes are established. (nature.com)

The mammalian blastocyst hatches before implantating into the endometrial lining of the womb. (wikipedia.org)
Depending on the species, a blastula or blastocyst stage embryo can appear as a ball of cells on top of yolk, or as a hollow sphere of cells surrounding a middle cavity. (wikipedia.org)
there is an implantation of blastocyst in the uterine wall and this occurs after two and half days after coitum (DPC), and gastrulation commences six and half DPC. (brainyhomeworkhelp.com)
Implantation of the blastocyst is a developmental milestone in mammalian embryonic development. (futuristech.info)
In the mouse, a transporting epithelium is established around the 8-16-cell stage through a process known as compaction where cell definition is lost and the outer cells of the embryo form tight junctions, giving rise to the blastocyst. (conditionmed.org)

Analysis of pre- and post-implantation embryos revealed that the majority of the lines exhibit mutant phenotypes that fall within a window of development between implantation and gastrulation with few pre-implantation and no post-gastrulation phenotypes. (umassmed.edu)
A model of the post-implantation human embryo derived from pluripotent stem cells. (caltech.edu)

Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development. (caltech.edu)

The reason for gastrulation is to form a body plan that serves in the succeeding embryo morphogenesis. (brainyhomeworkhelp.com)
The embryo of the frog Xenopus laevis is widely used as a model of cell polarization, migration, and morphogenesis due to its unique experimental advantages. (nature.com)

Green is posterior part similar to tail-end of an embryo, magenta is anterior part similar to developing heart cells, grey marks DNA. (scitechdaily.com)
Together, these results suggest that xCyp26c plays a specific role in anterior-posterior (A-P) neural patterning of Xenopus embryos. (molcells.org)

Sometimes this is called the pre-embryo a term employed to differentiate from an embryo proper in relation to embryonic stem cell discourses. (wikipedia.org)
During this fascinating process, a pluripotent stem cell population in the early embryo gives rise to the three germ layers from which all organ systems develop. (sanger.ac.uk)
However, it is disputed whether TBLCs are 'true' totipotent stem cells equivalent to in vivo two-cell stage embryos. (sciencegate.app)
The Rice lab employs a unique experimental system mimicking growth in confined spaces that allows human embryonic stem cells to divide and differentiate, but in a controlled shape similar to that of the embryo. (medicallyprime.com)
Self-organization of stem cells into embryos: A window on early mammalian development. (cam.ac.uk)
The generation of stem cell models of the embryo represents a powerful system with which to dissect this complexity. (cam.ac.uk)
Adding the stem cells for the extraembryonic lineages generates three-dimensional models that are more autonomous from the environment and recapitulate many features of the pre- and postimplantation mouse embryo, including gastrulation. (cam.ac.uk)
Using human embryos and human pluripotent stem cells, we show that the reorganization of the embryonic lineage is mediated by cellular polarization leading to cavity formation. (futuristech.info)
Here, we consider the metabolism of the early embryo through development, and look at the nutrient milieu within the developing stem cell niche. (conditionmed.org)
The developing embryo, from which pluripotent stem cells originate, undergoes a series of dynamic metabolic transitions synchronized to its molecular development. (conditionmed.org)
These studies led to our discovery of a novel type of pluripotent epiblast stem cell (EpiSC) from the late epiblast layer of mouse and rat embryos. (qscience.com)
Methylation at CpG islands of mammalian miR-9 genes was assessed in fetal murine neural stem cells (mNSCs) by methylation-specific PCR, and miRNA processing assessed by qRT-PCR for pre-miR-9 transcripts. (blogspot.com)
Generation of Stem Cell-Based Mouse Embryo-Like Structures. (caltech.edu)
Stem-cell-based human and mouse embryo models. (caltech.edu)
Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension. (caltech.edu)
Modeling human embryo development with embryonic and extra-embryonic stem cells. (caltech.edu)
Models of human development Pluripotent stem cells (PSCs: ESCs and iPSCs) create opportunities to address the ethical and technical constraints associated with the use of human embryos. (upf.edu)

Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo. (ox.ac.uk)
Genetic studies have identified the key signalling pathways and developmentally regulated transcription factors that govern cell lineage allocation and axis patterning in the early mammalian embryo. (ox.ac.uk)
At this time, a coordinated program of lineage diversification, cell-fate specification, and morphogenetic movements establishes the generation of extra-embryonic tissues and the embryo proper, and determines the conditions for successful pregnancy and gastrulation. (futuristech.info)
Embryos display key landmarks of normal development, including epiblast expansion, lineage segregation, bi-laminar disc formation, amniotic and yolk sac cavitation, and trophoblast diversification. (futuristech.info)

In other multicellular organisms, the word "embryo" can be used more broadly to any early developmental or life cycle stage prior to birth or hatching. (wikipedia.org)

He is most well known for his descriptions of phylogenetic trees, studies of radiolarians, and illustrations of vertebrate embryos to support his biogenetic law and Darwin's work with evolution. (asu.edu)
The T-box transcription factor eomesodermin (Eomes) has been implicated as an important component in germ layer induction and patterning in vertebrate embryos. (ox.ac.uk)
Isolation and expression analysis both in invertebrate and vertebrate embryos of a new homeobox containing gene named Orthopedia (Otp). (cnr.it)

Gastrulation is the formation of the three germ layers that will form all of the different parts of the body. (wikipedia.org)
Many visible changes in embryonic structure happen throughout gastrulation as the cells that make up the different germ layers migrate and cause the previously round embryo to fold or invaginate into a cup-like appearance. (wikipedia.org)
The morphogenetic movements of gastrulation rearrange the three germ layers precursors, positioning mesodermal cells between outer ectodermal and inner endodermal cells to shape the head-to-tail body axis. (nature.com)

During cleavage, the overall size of the embryo does not change, but the size of individual cells decrease rapidly as they divide to increase the total number of cells. (wikipedia.org)

Detecting cardiac contractile activity in the early mouse embryo using multiple modalities. (ox.ac.uk)

We are applying single cell sequencing techniques to profile the majority of the cells in mouse postimplantation embryos. (sanger.ac.uk)
Here we report the transcriptional profiles of 116,312 single cells from mouse embryos collected at nine sequential time points ranging from 6.5 to 8.5 days post-fertilization. (nih.gov)
Here, we describe approaches for visualizing contractile activity in the developing mouse embryo, using brightfield time lapse microscopy and confocal microscopy of calcium transients. (ox.ac.uk)
Gastrulation is a stage in the development of embryos in the mouse. (brainyhomeworkhelp.com)
In the Mus musculus (house mouse), gastrulation is like a continually changing process, three-dimensional puzzle that has specific characteristics when comparing it to non-mammals and other mammalian embryos. (brainyhomeworkhelp.com)
The preeminence of this period of development has been illustrated in loss of function studies conducted by the International Mouse Phenotyping Consortium (IMPC) which have shown that close to one third of all mouse genes are essential for survival to weaning age and a significant number of mutations cause embryo lethality before E9.5. (umassmed.edu)
We have isolated a novel mouse gene, Dll1 (delta-like gene 1), which maps to the mouse t-complex and whose deduced amino acid sequence strongly suggests that Dll1 represents a mammalian gene closely related to Drosophila Delta. (jax.org)

As epiblast continues to grow, the shape become cup like, with the rim situated on dorsal side of embryo. (brainyhomeworkhelp.com)
Gastrulation movements are orchestrated by a small, heterogeneous group of cells with inductive and morphogenetic properties located in the dorsal lip of the blastopore (DBL) of the amphibian gastrula known as the Spemann-Mangold organizer or dorsal organizer. (nature.com)

An embryo is an initial stage of development of a multicellular organism. (wikipedia.org)
Gastrulation is the next phase of embryonic development, and involves the development of two or more layers of cells (germinal layers). (wikipedia.org)
In human development, the term fetus is used instead of embryo after the ninth week after conception, whereas in zebrafish, embryonic development is considered finished when a bone called the cleithrum becomes visible. (wikipedia.org)
Recording and contextualizing the science of embryos, development, and reproduction. (asu.edu)
Haeckel aggressively argued that the development of an embryo repeats or recapitulates the progressive stages of lower life forms and that by studying embryonic development one could thus study the evolutionary history of life on earth. (asu.edu)
As the development of embryology grew in importance during the late 1800s, so did the need for models to show intricate details of embryos. (asu.edu)
Gastrulation is often referred to as the 'black box' period of human development, because legal restrictions prevent the culture of human embryos in the lab beyond day 14, when the process starts. (scitechdaily.com)
During mammalian development, the left and right ventricles arise from early populations of cardiac progenitors known as the first and second heart fields, respectively. (stanford.edu)
Through the definition of a coordinate system based on mesh structure and the development of a special sectioning procedure, sections can be localized within the intact embryo and three-dimensional coordinates given to any element of embryo volume. (sciencegate.app)
increased public sensitivity and awareness together with the development of national regulations of governance of human cloning and embryo research in general. (lifeissues.net)
Here, we discuss recent advances and experimental systems used to study mammalian germ cell development. (elsevierpure.com)
Embryonic development refers to the process of growth and development of embryo. (brainyhomeworkhelp.com)
Stage of embryonic development is a phase within the period of embryonic development that is marked by distinct growth changes in the embryo. (brainyhomeworkhelp.com)
Prenatal development is the process that occurs during pregnancy whereby an embryo gestates from fertilization to birth. (brainyhomeworkhelp.com)
Together, our results indicate that the critical remodelling events at this stage of human development are embryo-autonomous, highlighting the remarkable and unanticipated self-organizing properties of human embryos. (futuristech.info)
Temporal map during gastrulation of the retinoic acid effect on development and patterning of murine brain. (cnr.it)
Our study provides multiple genetic inroads into the molecular mechanisms that control early mammalian development and the etiology of human disease, in particular, the genetic bases of infertility and pregnancy loss. (umassmed.edu)
Our results support the idea that Delta- and Notch-like proteins are involved in cell-to-cell communication in mammalian embryos and suggest a role for these proteins in cellular interactions underlying somitogenesis and development of the nervous system. (jax.org)
Other species, such as birds, with a lot of yolk in the egg to nourish the embryo during development, undergo meroblastic cleavage. (opentextbc.ca)
Zebrafish embryos were exposed to EtOH during gastrulation, or injected with anti-miR-9 or nonsense control morpholinos during the 2-cell stage of development and collected between 24 and 72 hours postfertilization (hpf). (blogspot.com)
Expression of thyroid hormone regulator genes in the yolk sac membrane of the developing chicken embryo [1] "Thyroid hormones (THs) are essential for the correct development of nearly every structure in the body from the very early stages of development, yet the embryonic thyroid gland is not functional at these stages. (edu.au)

We show that this histone modification is first enriched at PCH in the whole embryo and evolves into a diffuse distribution in epiblast during its specification and maturation. (sciencegate.app)
At the whole-embryo level, there is an apparent correlation between the levels of acetyl CoA and levels of acetylation of a number of proteins including histones H3 and H2B. (irjs.info)

Gastrula is the term used in defining the process in which embryo undergoes gastrulation. (brainyhomeworkhelp.com)

Model organisms including mice and zebrafish have previously enabled scientists to gain some insights into human gastrulation. (scitechdaily.com)

After the cleavage has produced over 100 cells, the embryo is called a blastula. (opentextbc.ca)

Before implanting into the uterine wall the embryo is sometimes known as the pre-implantation embryo or pre-implantation conceptus. (wikipedia.org)
In vivo studies are particularly challenging for mammals after implantation, owing to the small size and inaccessibility of the embryo. (cam.ac.uk)
Remodelling of the human embryo at implantation is indispensable for successful pregnancy. (futuristech.info)

In mammals, primordial germ cells (PGCs) originate from peri-gastrulation embryos. (elsevierpure.com)

Shankar's group takes a multidisciplinary and collaborative approach to address these questions, using techniques spanning molecular genetics, lightsheet and confocal time-lapse imaging, single cell approaches, proteomics and embryo explant culture. (ox.ac.uk)

However, these models may behave differently from human embryos when the cells start to differentiate. (scitechdaily.com)
However, it contains a thick inner layer of cells at one end of the inner cavity, from which the embryo will develop (Campbell & Reece, 2005). (brainyhomeworkhelp.com)
Here, we review the principles of self-organization and how they set cells in motion to create an embryo. (cam.ac.uk)
The first of our time-traveling studies in this rejuvenation face-off takes inspiration from nature and studies the dynamics and mechanisms associated with the rejuvenation of DNA methylation profiles in the cells of the early mammalian embryo. (epigenie.com)
Our group is interested in how cells build embryos. (upf.edu)
In order to break the initial "egg shape" of the embryo, cells need to polarize in a precise and coordinated manner. (nature.com)
Recent studies in yeast and cultured mammalian cells have suggested that the intracellular Limonin irreversible inhibition level of acetyl CoA may play a role in the regulation of cell growth, proliferation and apoptosis, by affecting protein acetylation reactions. (irjs.info)

Cell signalling and transcriptional networks are known to regulate aspects of gastrulation, but the precise mechanisms have not been investigated at the single cell level. (sanger.ac.uk)

While these populations have been extensively studied in non-human model systems, their identification and study in vivo human tissues have been limited due to the ethical and technical limitations of accessing gastrulation stage human embryos. (stanford.edu)

For our understanding of gastrulation to be taken to another level, we need to measure the molecular behaviour of each individual cell so that we can see how decisions about cell specialisation are taken. (sanger.ac.uk)

Yolk sac lies outside the embryo connected by a yolk stalk ( vitelline duct , omphalomesenteric duct ) to the midgut with which it forms a continuous connection. (edu.au)
To clarify the roles of the egg yolk as a source of THs, the TH content in the yolk and the expression of TH regulator genes in the yolk sac membrane were evaluated throughout the 21-day incubation period of chicken embryos. (edu.au)
It is assumed that the chicken yolk sac inactivates THs contained abundantly in the yolk and supplies the hormones to the developing embryo in appropriate concentrations until the second week of incubation, while THs may be activated in the yolk sac membrane in the last week of incubation. (edu.au)
Additionally, the yolk sac could serve as a source of iodine for the embryo. (edu.au)

Human embryo polarization requires PLC signaling to mediate trophectoderm specification. (caltech.edu)
Depletion of xCyp26c by morpholino-oligonucleotides suppressed the normal formation of the axis and head, indicating that xCyp26c plays a critical role in the specification of anterior neural tissue in whole embryos. (molcells.org)

After treatment with chemical signals, the gastruloids were seen to lengthen along a head to tail axis, known as the anteroposterior axis, turning on genes in specific patterns along this axis that reflect elements of a mammalian body plan. (scitechdaily.com)

A newly developing human is typically referred to as an embryo until the ninth week after conception, when it is then referred to as a fetus. (wikipedia.org)
The model resembles some key elements of an embryo at around 18-21 days old and allows the researchers to observe the processes underlying the formation of the human body plan never directly observed before. (scitechdaily.com)
A better understanding of human gastrulation could also shed light on many medical issues including infertility, miscarriage, and genetic disorders. (scitechdaily.com)
This official collection contains a continuum of human embryos, including day-by-day growth over the first eight weeks. (scitechdaily.com)
They suggest that gastruloids partially resemble 18-21 day old human embryos. (scitechdaily.com)
An in-depth analysis aiming at re-defining this terminology according to the new developments in human embryo research would be highly beneficial . (lifeissues.net)
3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
Ref: Self-organization of the human embryo in the absence of maternal tissues. (futuristech.info)
Expression analysis of several Hox genes in human embryos. (cnr.it)

The first is to understand how the coordinated cell movements that shape the early mammalian embryo prior to and during gastrulation are controlled. (ox.ac.uk)
The coordinated cell movements result in a spatially organized embryo, and puts together the framework on which other features are to develop from into building the body. (brainyhomeworkhelp.com)
Cell polarization is essential during gastrulation, driving asymmetric cell division, cell movements, and cell shape changes. (nature.com)

The use of a mesh system allows identification of individual embryos by position, and control of their orientation during culture and preparation for light and electron microscopy. (sciencegate.app)
His group participates regularly in science festival, for which they have developed 3D printed models of developing embryos and a virtual reality based embryo and microscopy image volume explorer. (ox.ac.uk)

We work with mammalian ESCs because over the last decade advances in our ability to grow them and differentiate them in dishes and wells have opened up exciting experimental possibilities that we are exploiting. (upf.edu)

Anatomy58

Organisms30

Diseases4

Chemicals and Drugs65

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Phenomena and Processes61

Disciplines and Occupations3

Technology, Industry, Agriculture1

Information Science5

Health Care1

Mesoderm12

Differentiation5

Vitro14

Endoderm2

Organogenesis6

Pluripotent cells2

Embryogenesis6

Blastocyst5

Post-implantation2

Neurulation1

Morphogenesis2

Posterior2

Stem17

Lineage4

Developmental1

Vertebrate embryos3

Germ layers3

Size of the embryo1

Early mouse embryo1

Mouse7

Dorsal2

Development21

Whole embryo2

Undergoes1

Zebrafish1

Blastula1

Implantation3

Mammals1

Time lapse1

Cells7

Mechanisms1

Vivo1

Molecular1

Yolk4

Specification2

Axis1

Human9

Cell movements3

Microscopy2

Advances1