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  • germ
  • The article presents abstracts on stem cells including the primordial germ cell apoptosis which is being regulated by the human fetal ovary's bone morphogenetic protein (BMP) signaling, the multipotent status of human testis which is being affected by small molecules, and the transcriptomic. (ebscohost.com)
  • 4. What are the possible outcomes of a mutation in a somatic cell, compared to the possible outcomes of a mutation in a germ-line cell? (coursehero.com)
  • It has been found that the stem cell microenvironment can re-direct cell fate allowing crossing of primitive germ layer boundaries. (sciencedebate.com)
  • Spinal Cord I
  • While the Republicans were in charge of Congress, I don't think that there was any interest in holding such hearings on spinal cord injury, in the same way that there was not much interest in holding hearings on stem cell research. (rutgers.edu)
  • A Bay Area patient who recently suffered a serious spinal cord injury and is now paralyzed from the waist down joined the world's first-ever embryonic stem cell study in humans last week, when Stanford doctors injected 2 million cells designed to replace damaged neurons in the patient's spine. (cbc-network.org)
  • At the same time, there have been years of successful and peer reviewed adult stem cell studies involving patients paralyzed by spinal cord injury - in which patients have had feeling restored - which went virtually unreported . (cbc-network.org)
  • biology
  • I chose this area of biology because stem cells provided an intriguing topic. (writework.com)
  • The biology of NSCs is of considerable interest, reflecting not only their fundamental contribution to building the developing CNS but also their potential functional roles in the adult forebrain and their promise for treating neurological illness. (jneurosci.org)
  • That's really one of the great success stories of stem cell biology that gives us all hope," says Dr. David Scadden of Harvard, who notes stem cells are also used to grow skin grafts. (blogspot.com)
  • organs
  • He says it should be possible to develop replacement cells or even grow organs from the newly created stem cells. (voanews.com)
  • To battle aging, the human body holds a reservoir of nonspecialized cells that can regenerate organs. (eurekalert.org)
  • The multipotent cells resident in most body organs function to replenish aging, injured or dead cells throughout the lifespan of the organism, though aging adversely influences their ability to self-renew. (sciencedebate.com)
  • fetal
  • In earlier efforts to treat Parkinson's, transplanted fetal nerve cells had trouble making the correct level of dopamine - this problem will also have to be tackled. (grg.org)
  • The fetal cells came from a woman whose pregnancy was ended at fourteen weeks. (voanews.com)
  • 1992 ). Adult and fetal MSCs stained negatively for CD34 and CD45 and positively for CD73, CD105, and CD166 (Campagnoli et al. (pubmedcentralcanada.ca)
  • genes
  • It requires the knowledge of how and which genes are turned on and off, at the right time, to produce the desired cell type. (marymeetsdolly.com)
  • They said the fusing process caused the stem cell to reset the genes in the skin cell. (voanews.com)
  • It's not impossible for us to turn red blood cells into stem cells already: Viruses can be harnessed to set the clock back on the cells by delivering genes to them, but that can come with complications, like mutated genes or cancer. (planettechnews.com)
  • 10. How is it that human cells can make over 100,000 proteins with only 25,000 genes? (coursehero.com)
  • These cells were modified by a standard lab technique employing retroviruses customized to insert genes into the cell's DNA. (blogspot.com)
  • The inserted genes were Oct4, Sox2, Lif4 and c-Myc, known to act together as master regulators to keep cells in an embryonic-stem-cell-like state. (blogspot.com)
  • Potential alternatives include other forms of viruses, synthesized versions of the proteins created by the four master regulator genes that are modified to enter the cell nucleus, and small molecules, Hanna says. (blogspot.com)
  • transcription factors
  • Activity of four transcription factors distinguishes a small proportion of glioblastoma stem cells responsible for the aggressiveness and treatment resistance of the deadly brain tumor. (medindia.net)
  • Parkinson's
  • They are the only ones capable of generating any cell type from the hundreds of cell types that make up an adult organism, so they are the first step towards curing illnesses such as Alzheimer, Parkinson's disease or diabetes. (technologynetworks.com)
  • precursor
  • Radial glial cells (RGCs), a transient cell population present only in the developing CNS, function both as precursor cells and as scaffolds to support neuron migration. (jneurosci.org)
  • Shinya Yamanaka
  • The IPS cells were derived using modifications of the approach originally discovered in 2006 by the Shinya Yamanaka laboratory at Kyoto University. (blogspot.com)