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  • Bone Marrow
  • Bone marrow cells, in particular, were found to give rise to many cells besides those in the blood: in the skin, lung epithelium, kidney epithelium liver parenchyma, pancreas, skeletal muscle, heart muscle, endothelium, nerve cells in the cortex and cerebellum. (i-sis.org.uk)
  • Some of the cell types that have or are currently being developed include cardiomyocytes (CM), neurons, hepatocytes, bone marrow cells, islet cells and endothelial cells. (wikipedia.org)
  • genetic
  • It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. (wikipedia.org)
  • Genetic engineering does not normally include traditional breeding, in vitro fertilisation, induction of polyploidy, mutagenesis and cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process. (wikipedia.org)
  • Genetic biomarkers are particularly significant in cancer because most cancer cell lines carry somatic mutations. (wikipedia.org)
  • generate
  • A fertilized egg is said to be 'totipotent' because it has the potential to generate all cell types and tissues that make up an organism. (bioedonline.org)
  • For example, brain stem cells may be able to generate blood and skeletal muscle cells. (bioedonline.org)
  • The fertilized egg is said to be 'totipotent,' meaning that it has the potential to generate all the specialized cells and tissues of the body, as well as the tissues for its (the egg's) development in the uterus. (bioedonline.org)
  • Cells in the inner cell mass of the blastocyst also have the capacity to generate cells that develop into all of the tissues of the body. (bioedonline.org)
  • Stem cell cultures grown in the laboratory may be used to generate specialized, differentiated cells. (bioedonline.org)
  • immunosurgery
  • Immunosurgery is a method of selectively removing the external cell layer (trophoblast) of a blastocyst through a cytotoxicity procedure. (wikipedia.org)
  • Immunosurgery can be used to obtain large quantities of pure inner cell masses in a relatively short period of time. (wikipedia.org)
  • therapeutic
  • The rationale for this 'therapeutic cloning' was to provide a limitless source of dynamic cells with the same DNA as the cell donor. (nature.com)
  • A biomarker, or biological marker, is defined as a "cellular, biochemical or molecular alteration in cells, tissues or fluids that can be measured and evaluated to indicate normal biological processes, pathogenic processes, or pharmacological responses to a therapeutic intervention. (wikipedia.org)
  • nucleus
  • The variation in cell shapes is partially determined by the location of the nucleus within the cell, causing bulging in areas of the cells forcing the height and shape of the cell to change. (wikipedia.org)
  • Eukaryotic organisms (animals, plants, fungi and protists) store most of their DNA inside the cell nucleus and some of their DNA in organelles, such as mitochondria or chloroplasts. (wikipedia.org)
  • mammalian
  • The Tet-Off system for controlling expression of genes of interest in mammalian cells was developed by Professors Hermann Bujard and Manfred Gossen at the University of Heidelberg and first published in 1992. (wikipedia.org)
  • eukaryotic
  • In addition, its expression is considered to be more stable in eukaryotic cells due to being human codon optimized and utilizing 3 minimal transcriptional activation domains. (wikipedia.org)
  • Within eukaryotic cells DNA is organized into long structures called chromosomes. (wikipedia.org)
  • The eukaryotic cell condenses its genome into tightly packed chromatin and nucleosomes. (wikipedia.org)