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Stem Cell ResearchEmbryo ResearchEmbryonic Stem CellsStem CellsCatholicismBeginning of Human LifeDehumanizationStem Cell TransplantationHinduismEastern OrthodoxyJudaismBuddhismPersonhoodValue of LifeMoralsEthics, ResearchReligion and MedicinePluripotent Stem CellsEmbryo DispositionResearch Embryo CreationBiomedical ResearchRegenerative MedicineCell DifferentiationAdult Stem CellsInduced Pluripotent Stem CellsMetaphysicsBioethical IssuesComplicityResearchCell Culture TechniquesEmbryo, MammalianTotipotent Stem CellsHematopoietic Stem CellsPhilosophy, MedicalBioprintingTherapeutic MisconceptionPatents as TopicCell LineageFederal GovernmentLobbyingIslamCell BiologyPublicationsOctamer Transcription Factor-3Cell- and Tissue-Based TherapyNuclear ReprogrammingMesenchymal Stromal CellsNeural Stem CellsPublic PolicyCloning, OrganismTranslational Medical ResearchHematopoietic Stem Cell TransplantationStem Cell NicheRegenerationNeoplastic Stem CellsNational Institutes of Health (U.S.)Societies, ScientificMultipotent Stem CellsCell LineCells, CulturedCell ProliferationCell SeparationTissue EngineeringBiotechnologyNuclear Transfer TechniquesInformed ConsentMesenchymal Stem Cell TransplantationOocyte DonationInternational CooperationEmbryoid BodiesStem Cell FactorSOXB1 Transcription FactorsGene Expression Regulation, DevelopmentalHistory, 20th CenturyInternationalityPortraits as TopicUncertaintyTeratomaHomeodomain ProteinsClinical Trials, Phase I as TopicGerm CellsFetal Stem CellsGene Expression ProfilingUnited StatesGerm LayersPlant StemsFertilization in VitroChimeraResearch Support as TopicSignal TransductionFlow CytometryEndodermReverse Transcriptase Polymerase Chain ReactionLeukemia Inhibitory FactorTranscription FactorsModels, BiologicalHematopoiesisGene TargetingMice, Inbred C57BLStage-Specific Embryonic Antigens
EmbryosMouse embryonic stemDifferentiationGerm cellsHESCsESCsPluripotent cellsGenesResearchersRegenerativeScientistsGuidelines for Human Embryonic Ste2001TherapeuticFetal tissueTherapies2023TissueFundingOversightHESCAbstractTissuesScientificDiseasesGeneticAdvocatesParkinson'sDevelopmentAdvancesNeuronsProponentsESCRO CommitteeBiologyControversialSomatic cell nucMoralDebateTherapyMorallyEthicsDifferentiateCloningProgenitorAborted fetusesDerivationInvestigatorsKidney cellsClinical trialsConduct researchUmbilical cordContextDiseaseSupport1998
Embryos20
  • Embryonic stem cells are derived from early embryos and have the ability to differentiate into any cell type. (spiked-online.com)
  • One reason for these differences may be the development of induced pluripotent stem cells, which are derived from adult body cells rather than from embryos. (scienceblog.com)
  • The issue of research involving stem cells derived from human embryos is increasingly the subject of a national debate and dinner table discussions," said President George W. Bush in a 2001 speech announcing his policy on embryonic stem cell research. (erlc.com)
  • Where do the embryos for embryonic stem cells come from? (erlc.com)
  • If they have no intention of giving birth to these embryos, the couple can donate them for research purposes. (erlc.com)
  • Currently, all human embryonic stem cell lines in use today were created from embryos generated by IVF. (erlc.com)
  • Management of what is called the 'national embryo supply' in the UK involves new forms of governance at the 'IVF-Stem cell Interface', where questions about the provenance of donated embryos, including the ethics of their sourcing, are at a premium. (lse.ac.uk)
  • Michigan would join 47 other states in permitting research on human embryos and the creation of new embryonic stem cell lines in Michigan if Proposal 2008-02 is adopted by the voters on November 4. (crcmich.org)
  • It prohibits non-therapeutic research that jeopardizes the life or health of a human embryo, fetus, or neonate, thereby precluding research on embryos to derive human embryonic stem cell lines. (crcmich.org)
  • The scientists cited a 1996 federal law called the Dickey-Wicker Amendment that prohibits funding for 'research in which a human embryo or embryos are destroyed. (biopharminternational.com)
  • Earlier this week, the British House of Commons voted by a large majority the amendments for Human Fertilization and Embryonic Research Act which allows scientists to produce human-animal hybrid embryos for stem cell research. (battlingforhealth.com)
  • The cost seems to be small, experimentation with stem cells derived from "spare" embryos that are no longer needed or wanted for in vitro fertilization. (jcrelations.net)
  • The ESCRO Committee's review shall be specific to the scientific and ethical issues presented by proposals to use human gametes, human embryos, human embryo models, and the development and study of human embryonic stem cells (hESCs) or human induced pluripotent stem cells (hIPSCs) and their pluripotent derivatives in covered research in particular research projects. (washington.edu)
  • Scientists announced this week that they have successfully produced embryonic stem cells by transferring the DNA of human skin cells into unfertilized human eggs to produce embryos, a technique the Church considers to be an abuse of human life. (womenofgrace.com)
  • These embryos are flexible and have more potential than the adult stem cells, according to the National Institutes of Health (NIH), Embryonic stem cells can become all cell types of the body because they are pluripotent. (oxodocs.com)
  • In addition to that, Dr. Richard Maurice in his article titled Key Ethical Issues in Embryonic Stem Cell Research published for the Department of the Parliamentary Library in Australa, the probability of IVF embryos developing into full-term successful births is low. (oxodocs.com)
  • Embryonic stem cell research "uses special cells found in three-to-five day old human embryos to seek cures for a host of chronic disease" (PRC). (ipl.org)
  • Stem cells may be derived from adult tissues but the most potent are extracted from developing human embryos. (edu.au)
  • Since all these approaches involve the manipulation of human gametes, embryos or embryonic cells, and could also permit more contentious uses, they have stimulated a controversial debate as to what aims are desirable and to what extent experiments on human embryos are morally permissible, if permissible at all. (springer.com)
  • Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
Mouse embryonic stem2
Differentiation11
  • The exact process of differentiation is not yet understood and although embryonic stem cells can, in principle, provide for all human tissue, scientists are some way from controlling the process. (spiked-online.com)
  • Here, I review the progress made in understanding how signals from the environment influence pluripotent cell self-renewal and differentiation and discuss some of the differences encountered between pluripotent cells from various species and distinct developmental origins. (dundee.ac.uk)
  • Thoma et al observed that Ngn2 alone is sufficient to induce neuronal differentiation in embryonic stem cells. (bartleby.com)
  • Innovations in stem cell culture and differentiation techniques. (markwideresearch.com)
  • Mammalian SWI/SNF [also called Brg/Brahma-associated factors (BAFs)] are evolutionarily conserved chromatin-remodeling complexes regulating gene transcription programs during development and stem cell differentiation. (ox.ac.uk)
  • Furthermore, differentiation of trophoblast stem cells in the presence of PFI-3 was markedly enhanced. (ox.ac.uk)
  • The data present a key function of BAF bromodomains in stem cell maintenance and differentiation, introducing a novel versatile chemical probe for studies on acetylation-dependent cellular processes controlled by BAF remodeling complexes. (ox.ac.uk)
  • This is a time-sensitive RFI to determine how best to accelerate research directed toward targeted differentiation of human embryonic stem cells (hESCs) into specific neuronal and glial cell types. (nih.gov)
  • Through the use of human embryonic stem cells (hESCs), we can mimic brain development towards different regions of the human brain, and thereby investigate the effect of novel genes on neural differentiation. (lu.se)
  • EE selectively increased cell differentiation into MSN phenotype and promoted host-to-graft connectivity. (lu.se)
  • Finally, there is a discussion about the mechanisms behind the self-renewal and differentiation of stem cells and the role of stem cells in renewal of the body's tissues. (lu.se)
Germ cells2
HESCs5
  • With the unlimited self-renewal capability and the pluripotency to differentiate into all cell types in the body, human embryonic stem cells (hESCs) with causative genetic mutations as well as their differentiated derivatives represent the much needed human disease models for studies on disease mechanisms and for drug development. (ca.gov)
  • The UW Institute for Stem Cell and Regenerative Medicine (ISCRM) has been established for the purpose of facilitating and encouraging basic research on hESCs to develop therapies and cures for human disease. (washington.edu)
  • Human embryonic stem cells (hESCs), with their regenerative potential, hold promise for revolutionary advancements in regenerative medicine and disease treatment. (markwideresearch.com)
  • The report by MarkWide Research provides valuable insights for researchers, biotech companies, and investors committed to harnessing the regenerative power of hESCs. (markwideresearch.com)
  • Cell replacement using human embryonic stem cells (hESCs) derivatives may offer new therapeutic opportunities to replace degenerated neurons and repair damaged circuits. (lu.se)
ESCs6
  • Embryonic stem cells (ESCs) are stem cells that have been taken from the inner cell mass of a blastocyst, an embryo of about 150 cells that has not yet implanted into a woman's uterus. (erlc.com)
  • Embryonic Stem Cells (ESCs) Research is back in the news again. (oxodocs.com)
  • There are various ways to obtain stem cells: blood cells (extracted from the umbilical cord blood, after a baby is born), bone marrow donation (from existing human beings), and the ESCs from the fertility clinics. (oxodocs.com)
  • Scientists, on the other hand, have a different view on what is life, they argue that ESCs are pluripotent, ESCs hold the possibility of developing into any organ of the body, yet, according to National Institutes of Health (NIH), [ESCs] are typically four or five days old and are a hollow microscopic ball of cells called the blastocyst. (oxodocs.com)
  • An idea just in the planning stage is to select embryonal stem cells (ESCs) in vitro for phenotypes that may retard aging. (jax.org)
  • Conditional ablation of Pcgf6 in ESCs leads to robust de-repression of such germ cell-related genes, in turn affecting cell growth and viability. (ox.ac.uk)
Pluripotent cells1
Genes8
  • Alternatively, transgenesis and gene targeting techniques can be used to introduce the patient's genes into the stem cell line. (spiked-online.com)
  • PCGF6 thus links sequence specific target recognition by the MAX/MGA complex to PRC1-dependent transcriptional silencing of germ cell-specific genes in pluripotent stem cells. (ox.ac.uk)
  • Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
  • The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
  • Below is a non-exhaustive list of in-house infrastructures that are categorized into three overarching themes: bio-imaging, proteins, genes & cells and other resources. (lu.se)
  • Below you can see some examples of the infrastructure for research on genes and cells, available for researchers at Lund University. (lu.se)
  • In addition to infrastructures for bioimaging, protein and genes & cells, we also provide other resources e.g., databases, networks and specialized labs. (lu.se)
  • For gene therapy, a combinatorial approach with multiple target genes, as well as more complex optogenetic approaches are studied, while for cell-therapy human induced pluripotent stem cells and human induced neuronal cells are investigated. (lu.se)
Researchers8
  • Researchers may, however, conduct research on embryonic stem cell lines created outside of Michigan and may study adult stem cells. (crcmich.org)
  • The researchers note, in a media release from the University of Edinburgh, that this could pave the way for clinical trials of stem cell therapies to treat conditions such as Parkinson's disease and spinal cord injury. (rehabpub.com)
  • The researchers note in the release that this highlights the need for continued genetic testing of stem cell-based products to ensure that they are suitable for use in patients. (rehabpub.com)
  • The move was celebrated by researchers hoping to use such cells for research, but it is likely that the decision will be appealed. (biopharminternational.com)
  • As a general proposition, the state taxpayers underwriting efforts such as Proposition 71 have the expectation that money will be used for research, not to litigate the patent positions of prior researchers. (samsung-printer-support.com)
  • Some suggest that it is Congress' role to tell researchers what kinds of cells to use. (ontheissues.org)
  • Researchers have been able to turn skin cells into stem cells in mice, giving researchers an unlimited supply of cells straight from the patient from which to creare therapies. (strata-sphere.com)
  • Researchers hope to use these cells to grow healthy tissue to replace injured or diseased tissues in the human body. (medlineplus.gov)
Regenerative13
Scientists16
  • Scientists anticipate that in the future stem cell lines will provide a virtually unending supply of pancreatic cells for diabetic patients, neuronal cells for patients with neural disorders such as Parkinson's or Alzheimer's disease, and a host of heart cells that may treat a variety of cardiac problems. (spiked-online.com)
  • It might be expected that the richest nation on Earth would encourage its top scientists to pursue this work with vigor rather than limiting funding opportunities, creating legal barriers and fencing off any newly developed cell lines. (spiked-online.com)
  • Levine reasons this could be a result of the fact that there are many incentives for scientists to work with existing human embryonic stem cell lines rather than creating new ones. (scienceblog.com)
  • An interesting question going forward is how committed these scientists are to stem cell research or if they are relating their work to stem cells now simply to be eligible for state funding - that's unknown right now. (scienceblog.com)
  • By learning how stem cells differentiate and become specialized, scientists hope to gain a better understanding of how cells in general work and what can go wrong. (erlc.com)
  • Umbilical Cord Blood Storage Company Sees Growth Umbilical Cord Stem Cell Storage Resources Arkansas House Votes to Create Umbilical Cord Stem Cell Bank Scientists Claim They Discovered Molecule That Might Help Embryonic Stem Cells Grow US Senate Vote for. (physiciansforlife.org)
  • I have been asked to comment on the latest news that scientists are now able to harvest embryonic stem cells without killing the embryo. (christianliferesources.com)
  • The case began when a lawsuit was brought against the National Institutes of Health (NIH) by Dr. James Sherley and Dr. Theresa Deisher, scientists opposed to embryonic stem cell research. (biopharminternational.com)
  • The scientists also claimed that funding embryonic stem cell research hurt their ability to receive federal funding for their own research using adult stem cells. (biopharminternational.com)
  • This is a momentous day-not only for science, but for the hopes of thousands of patients and their families who are relying on NIH-funded scientists to pursue life-saving discoveries and therapies that could come from stem cell research. (biopharminternational.com)
  • It is the belief of many scientists, lawmakers, as well as patients that the key to future therapies that can cure diseases - from cardiovascular disorders to cancer - lie in stem cell research. (battlingforhealth.com)
  • Scientists at Stanford University in California have been able to coax embryonic stem cells into becoming eggs and sperm, which could one day lead to the creation of children through entirely artificial means. (womenofgrace.com)
  • British scientists are hailing the recent creation of human sperm cells that they believe could revolutionize fertility treatment. (womenofgrace.com)
  • scientists hope that one day, they could use stem cells as a promising avenue to cure the dying patients. (oxodocs.com)
  • Scientists must always be mindful of ethics as they proceed, yet a populist balancing of complicated scientific understanding and ethics has the potential of being regressive in its emotive and sometimes ignorant reactions on a variety of research topics. (stephentaylor.ca)
  • In view of this situation the Europäische Akademie assembled a temporary interdisciplinary project group in which scientists from universities and non-university research organizations in Europe working on the relevant subjects were brought together and charged with establishing a knowledge base and providing suggestions for long-term solutions that would be acceptable for society. (springer.com)
Guidelines for Human Embryonic Ste3
20013
  • In addition, states varied substantially in the extent to which they prioritized human embryonic stem cell research, and much of the research performed in the states could likely have been funded by the National Institutes of Health under federal guidelines established by President Bush in 2001. (scienceblog.com)
  • This issue was considered by the House of Representatives Standing Committee on Legal and Constitutional Affairs in its report entitled Human Cloning: Scientific, Ethical and Regulatory Aspects of Human Cloning and Stem Cell Research (hereafter the Andrews Report , after the Chair of the Committee, Mr Kevin Andrews, MP) released in September 2001. (edu.au)
  • 5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
Therapeutic5
  • A renewable, tissue culture source of human cells capable of differentiating into a wide variety of cell types would have broad applications in basic research and therapeutic techniques. (spiked-online.com)
  • No end believed to be good, such as the use of [embryonic] stem cells for the preparation of other differentiated cells to be used in what look to be promising therapeutic procedures, can justify [the destruction of embryonic life]. (jcrelations.net)
  • There is great potential for therapeutic advances derived from such research. (stephentaylor.ca)
  • Therapeutic cloning, which creates embryonic stem cells . (medlineplus.gov)
  • Conclusions: The data support the long-term therapeutic potential of ESC-derived human striatal progenitor grafts for the replacement of degenerated striatal neurons in HD and suggest that EE can effectively accelerate the maturation and promote the integration of human striatal cells. (lu.se)
Fetal tissue2
  • In this article R. Alta Charo states that we have a right to use fetal tissue for research and therapy (Fetal Tissue, 1) The article goes into how a lot of people find this to be a moral issue and a matter of the conscience and explains how the antiabortion activist that don't agree with the research are actually benefitting from the fetal tissue. (ipl.org)
  • Over 60 organizations, including the Association of American Universities, wrote to Senate leaders opposing prohibitions or restrictions that would further impede the use of federal funding for fetal tissue or embryonic stem cell research. (aau.edu)
Therapies5
  • Ethical adult stem cell research is succeeding and yielding therapies that are healing people now. (pacatholic.org)
  • Dr. Gary Friedman of the New Jersey Stem Cell Research and Education Foundation explained how successful stem cell therapies will be more important as the aging American population puts a strain on our health care system. (pacatholic.org)
  • For example, stem cell therapies might help the people on the rapidly growing organ transplant list. (pacatholic.org)
  • Raising awareness and understanding of stem cell therapies. (markwideresearch.com)
  • They range from new options for infertility treatment and pre-implantation genetic diagnosis to stem-cell-based therapies for debilitating diseases. (springer.com)
20232
Tissue6
  • Current screening of potential new drugs is done using cell lines derived from animals or 'abnormal' human tissue such as tumor cells. (spiked-online.com)
  • Adult Stem Cells Taken from Human Fat Tissue Used to Treat Heart Failure Sweden Company Wants To Start First Stem Cell Research Factory Leading Scientist Charges Colleagues With "Misleading" Public British Stem Cell Researcher: Benefits of. (physiciansforlife.org)
  • The ban on funding did not apply to stem cells derived from adult tissue. (biopharminternational.com)
  • The University has further concluded that such research offers significant potential to develop treatments for many serious and debilitating human diseases, disorders, and health conditions, including genetic diseases, tissue injuries, spinal cord injuries, degenerative diseases such as heart disease, and various diseases of the nervous system and other organs. (washington.edu)
  • Cloning describes the processes used to create an exact genetic replica of another cell, tissue or organism. (medlineplus.gov)
  • Mechanistically, loss of C3aR and C5aR increases regulatory T cell (Treg) accumulation in the subcutaneous white adipose tissue during cold exposure or high-fat diet. (bvsalud.org)
Funding16
  • From what I could tell, only a relatively small portion of the stem cell research supported by these states was clearly ineligible for federal funding," said Levine, who is on the faculty of the School of Public Policy in the Ivan Allen College of Liberal Arts. (scienceblog.com)
  • In July, President George Bush vetoed a bill that would have provided federal funding for embryonic stem cell research. (pacatholic.org)
  • She contends that without state funding Pennsylvania might be a "follower" instead of a "leader" in stem cell research which could hurt the Commonwealth's economy. (pacatholic.org)
  • 29, 2011, a federal appeals court has lifted a ban on federal funding for embryonic stem cell (ESC) research. (biopharminternational.com)
  • In August 2010, a district court agreed with the plaintiffs that embryonic stem cell research violated federal law and blocked funding, but a three-judge appeals court temporarily lifted the ban in September. (biopharminternational.com)
  • The issue is whether that law's restrictions apply to research conducted on stem cell lines that had been developed without federal funding. (biopharminternational.com)
  • NIH has interpreted the law narrowly, and argued that creating embryonic stem cells is not the same as using lines created without federal funding for research purposes. (biopharminternational.com)
  • Funding for stem cell research in two of the most liberal states in the nation - California and Maryland - appears to be shifting away from embryonic to adult stem cells. (womenofgrace.com)
  • Extrapolating further, state funding to achieve patent positions could lead to a balkanization of research, in which entities from individual states (such as California, New Jersey, Maryland, Illinois, Connecticut) are fighting one another, rather than collaborating. (samsung-printer-support.com)
  • The European Commission yesterday (July 9) published its proposed guidelines for funding human embryonic stem cell research. (the-scientist.com)
  • Funding in this field by the EU's 6th Research Framework Programme (FP6) has been on hold while the commission attempted to balance the ethical concerns of some member states against the eagerness of others to proceed. (the-scientist.com)
  • The new guidelines will allow funding of the research but impose strict controls. (the-scientist.com)
  • The pace of scientific development has been directly promoted by substantial increases in OECD (Organisation for Economic Cooperation and Development) government funding for genetic and biotechnological research. (edu.au)
  • At the time, less than one year after 9/11, I was told that when professors made grant applications to federal funding agencies, they would try to find a link between their research and counter-terrorism in order to secure funding. (stephentaylor.ca)
  • Unfortunately for our funding, malaria is a highly unlikely infectious disease for use in terrorism and studying new ways of combating the malaria parasite directly (which is what we were researching) has nothing to do with climate. (stephentaylor.ca)
  • The ICMR fosters a research culture by improving funding, mainly for developing infrastructure. (who.int)
Oversight4
HESC7
  • ESCRO Committee membership reflects the scientific, medical, and ethical expertise necessary to review hESC research applications and includes unaffiliated community members from the public. (washington.edu)
  • In making decisions about policies and procedures governing the conduct of hESC research, the UW and the ESCRO Committee will provide reasonable opportunities for investigators who are part of ISCRM to express their views on such matters and consider such views in making decisions. (washington.edu)
  • The ESCRO Committee and ISCRM will strive to cooperate in establishing efficient mechanisms for the review of hESC research proposals and the training of hESC research investigators. (washington.edu)
  • To easily edit the genome of naïve human embryonic stem cells (hESC), we introduced a dual cassette encoding an inducible Cas9 into the AAVS1 site of naïve hESC (iCas9). (unamur.be)
  • Addressing ethical and legal complexities surrounding hESC research. (markwideresearch.com)
  • Navigating the complex ethical and legal landscape of hESC research. (markwideresearch.com)
  • Advancing hESC research for clinical applications. (markwideresearch.com)
Abstract1
  • abstract = "Since their discovery more than 30 years ago, embryonic stem (ES) cells have been propelled from relative obscurity into the centre stage of international attention. (dundee.ac.uk)
Tissues5
  • Blastocytes obtained through nuclear transfers would be used to generate the embryonic stem cells that could be differentiated to specific tissues or organs for transfer to the nuclear donor. (spiked-online.com)
  • Second, stem cells may prove to be an indispensable source of transplantable cells and tissues for repair and regeneration. (erlc.com)
  • Stem Cell Research- Embryonic Research and use of ste cells/ tissues from aborted fetuses for medical research and advancement of life, pros and cons. (onlinetutors247.com)
  • Is it ethical for doctors to use cells/tissues from aborted fetuses and ovarian tissues from dead women to prolong life in others? (onlinetutors247.com)
  • Our facilities provide the opportunity to study protein structure, molecular probes and drug design, system biology and molecular interactions in cells and tissues. (lu.se)
Scientific8
  • There are two main reasons stem cells are of interest to both scientific and medical research. (erlc.com)
  • The University of Washington believes that such covered research is essential to expanding fundamental scientific knowledge of cellular and developmental human biology. (washington.edu)
  • Is it right for one's life to be manipulated for the use of scientific research or is it just a evasion on the person's privacy. (ipl.org)
  • In other research areas, commercial pressures have resulted in a changed culture with regard to scientific announcements. (edu.au)
  • This has led the National Health and Medical Research Council (NHMRC) to publish guidelines on the requirement for appropriate qualifications to scientific announcements to avoid unrealistic expectations in the community for the early introduction of medical products. (edu.au)
  • 3 The resolution recognizes the need to respect the freedom of ethical scientific research and to ensure access to the benefits of its application. (who.int)
  • Thanks to our world-class research infrastructure, Lund University is well equipped to help lead the way towards future scientific breakthroughs. (lu.se)
  • On completion of the course, the students shall be able to · reflect on societal opportunities and consequences arising from developmental biology research and knowledge, and discuss these with individuals in the same education cycle · reflect on current scientific challenges and ethical issues in developmental and stem cell biology research and how this influences society in general. (lu.se)
Diseases11
  • Unlike abortion, the purpose of ESC research is to cure potential diseases and disabilities such as Parkinsons disease, diabetes, Alzheimers, stroke, and spinal cord injuries. (oxodocs.com)
  • While at the hospital she was unaware that the doctors there were experimenting on her taking cell samples from her body, to help find a resolution to multiple diseases. (ipl.org)
  • All of this debate raises an important question, Should embryonic stem cell research be conducted for treatment of present and future diseases? (ipl.org)
  • On the other hand, people who believe that embryonic stem cell research creates means of curing diseases reply that the research should be conducted. (ipl.org)
  • But proponents say stem cell research could cure diseases. (go.com)
  • The regional research centres concentrate on research pertaining to the diseases of their particular region, where there is often a lack of proper government infrastructure for health care delivery. (who.int)
  • Symptoms and Signs Amyotrophic lateral sclerosis and other motor neuron diseases are characterized by steady, relentless, progressive degeneration of corticospinal tracts, anterior horn cells, bulbar motor nuclei. (msdmanuals.com)
  • Building on the strong tradition of cutting-edge research on Parkinson's and Alzheimer's diseases at Lund University, the vision is to create new and innovative strategies for improved and novel treatments, disease modifications and eventually cures for neurodegenerative diseases. (lu.se)
  • MultiPark is striving to understand the mechanisms of neurodegenerative diseases, and to create a dynamic structure for the advancement of research, innovation and education in the field. (lu.se)
  • Ultimately, our research will improve functioning, health and quality of life of people living and ageing with these diseases. (lu.se)
  • The main objective of the Stem Cell Center´s Neuroscience Program is to study the properties of neural stem cells (NSCs) and explore the possibilities to use these cells for treatment of neurodegenerative diseases such as Parkinson's disease and stroke. (lu.se)
Genetic10
  • Banking of multiple cell lines with varying genetic spectrum that can be matched to patients is one possibility. (spiked-online.com)
  • Here, the stem cell line is created using the genetic properties of the prospective recipient via somatic cell nuclear transfer. (spiked-online.com)
  • An independent study of the genetic makeup of human embryonic stem cells suggests that these cells are fit to use in humans. (rehabpub.com)
  • More than half of the cell lines carried large but stable genetic differences. (rehabpub.com)
  • They also found that a small number of the cell lines acquired genetic problems if they were grown in the laboratory for too long. (rehabpub.com)
  • 5. Most countries in the African Region have no specific regulations and policies governing genetic manipulations for assisted conception, treatment and research. (who.int)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
  • However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
  • UNESCO development of national ethics committees (NECs) and also reflected on recent surveys, including the 2014 NEC establish effective mechanisms of regional harmonization survey, and the 2009 UNESCO regional Legal survey, which and cooperation to address emerging issues related to bio- covered 10 issues related to medical and genetic research in ethics. (who.int)
Advocates5
  • Advocates of ESC research, however, argue that it is unethical to impede potential advances that could heal disease and relieve the suffering of fully developed human beings. (erlc.com)
  • He reiterated that the Catholic Church does not oppose stem cell research, but advocates research on non-embryonic cells that does not destroy human life. (pacatholic.org)
  • Advocates of stem cell research believe that the cells are not equivalent to human life because it is inside the womb even facing the fact that the start of a human life is in the moment of conception. (ipl.org)
  • According to its emotional advocates, the "debate is over" and one could conclude from such a conclusive declaration that further research is unnecessary and that it is action which is needed. (stephentaylor.ca)
  • Advocates with or without a strong grasp of the cellular basis of life (and/or what constitutes human life) constitute both sides on the debate regarding research involving these cells. (stephentaylor.ca)
Parkinson's2
  • As we have a strong focus on developing cells for cell replacement therapy in Parkinson's disease, we are currently adapting our protocols for GMP compliance through the EU-funded network NeuroStemcellRepair. (lu.se)
  • The clinical team from Lund headed by Prof. Olle Lindval in collaboration with Prof. Anders Björklund, were the first to show in patients the proof of principle that cell transplantation therapy is feasible approach to treat the patients with Parkinson's disease. (lu.se)
Development12
  • All specialized cells arise originally from stem cells, and ultimately form a small number of embryonic cells that appear during the first few days of development. (erlc.com)
  • This procedure remains problematic because human life at this stage of the development is exceptionally fragile, and therefore this cell-extraction procedure is extremely dangerous. (christianliferesources.com)
  • Disease research and drug development models based on genetically altered human embryonic stem cells. (ca.gov)
  • Induced pluripotent stem cells (iPS cells) generated by reprogramming of somatic cells are also discussed and related to the pluripotent cell states which can be captured during normal embryonic development. (dundee.ac.uk)
  • Of course this argument must overcome the facts of fetal development, but if it is defended successfully, embryonic stem-cell research is a moral piece of cake. (blogspot.com)
  • We also find a role for PCGF6 in pre- and peri-implantation mouse embryonic development. (ox.ac.uk)
  • The bill, introduced Jan. 18 by State Sen. Ralph Shortey , prohibits the manufacture or sale of "food or any other product intended for human consumption which contains aborted human fetuses in the ingredients or which used aborted human fetuses in the research or development of any of the ingredients. (go.com)
  • Shortey declined to give specific examples but said some food manufacturers used stem cells in the research and development process. (go.com)
  • There is a potential that there are companies that are using aborted human babies in their research and development of basically enhancing flavor for artificial flavors," he told KRMG Radio . (go.com)
  • Stem cell technology is the latest development in this controversial branch of science. (edu.au)
  • The ethical and legal controversies that were aroused in the ART debates during the 1980s have been re-ignited with the development of stem cell technology. (edu.au)
  • Furthermore, the course covers the most important processes in early embryo development, such as fertilisation, cell division, establishment of position information, polarity and asymmetries, and formation of body axes and gastrulation as preconditions for extremity development, regeneration and formation of the body's most important organs. (lu.se)
Advances1
  • During a recent appearance on the Oprah Winfrey show, the popular cardiovascular surgeon and television personality, Dr. Mehmet Oz, announced to a stunned audience that due to advances in adult stem cell technology, the debate over embryonic stem cells "is dead. (womenofgrace.com)
Neurons6
  • Ectopic expression of Ngn2 was sufficient to form mature neurons from embryonic stem cells[5]. (bartleby.com)
  • However, with a growing number of novel cell sources (stem cells and reprogrammed cells) it becomes important to develop new methodologies for a more thorough assessment of human neurons generated using these approaches. (lu.se)
  • We utilise monosynaptic tracing technology, using pseudotyped rabies vectors, in order to visualise the synaptic contacts formed between host neurons and graft human cells. (lu.se)
  • The cells are called induced neurons (iNs) and offer a shortcut over induced pluripotent stem cells (iPSc) for generating patient and disease-specific neurons. (lu.se)
  • Current efforts focus on identifying the optimal starting cell population for neural conversion, identification of gene combinations that yield subtype specificity and analysis of function and integration of the reprogrammed neurons. (lu.se)
  • Prof. Lindvall and Dr. Kokaia were the first in the world to show that the brain produces new neurons in response to stroke which opened new possibilities for cell therapy by developing the way to modulate and direct brains this self-repair mechanisms. (lu.se)
Proponents1
  • Proponents of this controversial research will now pressure state government to support their efforts. (pacatholic.org)
ESCRO Committee3
  • The National Academies' Guidelines make clear that activities related to human embryonic stem cell research should be overseen by an ESCRO committee. (wikipedia.org)
  • ESCRO Committee members are appointed by, and serve as advisors to, the Office of the Vice Provost for Research. (washington.edu)
  • ESCRO Committee review and approval shall be deemed to be separate from, and in addition to, any other reviews or approvals otherwise required at the UW for such research, including but not limited to committees or administrative offices having responsibility for review and approvals of human subjects research, animal research, biological safety, radioactive materials, and environmental safety. (washington.edu)
Biology5
  • The composition of ESCRO committees was specified to include representatives of the public and people with expertise in developmental biology, stem cell research, molecular biology, assisted reproduction, and ethical and legal issues in human embryonic stem cell research. (wikipedia.org)
  • Skottman, H 2010, ' Derivation and characterization of three new human embryonic stem cell lines in Finland ', In Vitro Cellular & Developmental Biology - Animal , vol. 46, no. 3-4, pp. 206-209. (tuni.fi)
  • Our mandate is to undertake and support research, not only basic, applied or epidemiological research but also operational research in the area of public health using a variety of tools, including those of modern biology. (who.int)
  • The whole course is based on five week-long modules on selected subjects related to issues concerning developmental biology and stem cells. (lu.se)
  • Lund center for Stem Cell Biology and Cell Therapy is one of six Swedish strategic centers of excellence in life sciences, supported by the Swedish Foundation for Strategic Research. (lu.se)
Controversial3
Somatic cell nuc1
  • Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
Moral2
  • Understood in this way, the moral context of embryonic stem cell research from a Roman Catholic point of view involves the acceptance of the idea that the benefits given to so many in society come through the destruction of the weakest and most vulnerable forms of life. (jcrelations.net)
  • A new controversy is brewing over government backing of Ebola vaccines that are using aborted fetal cell lines even though vaccines developed from moral alternatives are just as effective. (womenofgrace.com)
Debate2
  • Let's practice some forced reasonableness today on the roiling debate over embryonic stem-cell research. (blogspot.com)
  • Presented here are the results of this project, ranging from a discussion of the theoretical and practical possibilities in human-embryo experimentation and its alternatives in research on adult stem cells, a comparison of the situations and prospects of regulation of embryo research in Europe, a survey of European public attitudes, and a philosophical analysis of the arguments and argumentative strategies used in the debate. (springer.com)
Therapy5
  • The U.S. Food and Drug Administration (FDA) has approved the world's first human clinical trial of a therapy involving embryonic stem cells, a move that has been condemned by the Vatican as "unacceptable. (womenofgrace.com)
  • They argue that the research supports abortions but have taken part in receiving vaccines and therapy that comes from the research. (ipl.org)
  • The possibility to isolate and propagate NSCs and their potential applications in cell therapy have attracted a lot of research interest in recent years. (lu.se)
  • The work with stem cell-based therapy in stroke is in initial phase and recently Dr. Zaal Kokaia started a consortium within EU to develop the preclinical protocol for cell therapy in stroke. (lu.se)
  • Main emphasis of Epilepsy Center is to explore mechanisms underlying epileptogenesis, and develop gene- and cell-therapy based treatment strategies for epilepsy. (lu.se)
Morally2
  • as Pope John Paul II clearly stated, embryonic research is morally unacceptable. (oxodocs.com)
  • Or, as some would argue, were emotionally-driven second thoughts necessary to preserve ethics in science (or at least that which is funded in part by people morally opposed to such research)? (stephentaylor.ca)
Ethics2
  • This statement shows that, from a Roman Catholic point of view, the starting point for reflection on the ethics of embryonic stem cell research does not begin with stem cell research in itself nor even with the social good that comes about from the possible results of such research. (jcrelations.net)
  • Assisted reproductive technology (ART) and embryo research have posed many challenges to the different timeframes of science, ethics and law. (edu.au)
Differentiate1
  • As stem cells within a developing human embryo differentiate within the cell, their capacity to diversify generally becomes more limited and their ability to generate many differentiated cell types also becomes more restricted. (erlc.com)
Cloning1
  • Egg harvesting and Embryonic Stem-cell Research Pose Serious Threat to Women's Health A congressional hearing last Thursday raised awareness on the risks to women's health and fertility by in vitro fertilization (IVF), human cloning, embryonic stem-cell. (physiciansforlife.org)
Progenitor1
  • Recent studies have isolated distinct cell populations from infantile hemangiomas that display properties equivalent to aberrant progenitor cells, suggesting that, in addition to malignant tumors, benign tumors may also contain a stem cell-like component. (medscape.com)
Aborted fetuses2
Derivation1
  • This article explores the question of embryo donation to stem cell research from the perspective of the increasing proximity of IVF and hES cell derivation, using a model of 'double reproductive value' to explore what forms of exchange and flow are occurring, and how these are defined and negotiated in the context of a national hES cell coordination network of practitioners. (lse.ac.uk)
Investigators1
  • It is the University's policy to permit and encourage qualified investigators to engage in responsible and ethical research involving covered research. (washington.edu)
Kidney cells2
  • These cells are multipotent, meaning they can give rise to several other differentiated and specialized cells of the body (for example, liver cells, kidney cells, brain cells). (erlc.com)
  • Shortey may be acting on claims that the San Diego-based company Semonyx used proteins derived from human embryonic kidney cells to test artificial sweeteners, NPR reported . (go.com)
Clinical trials3
Conduct research1
  • and the costs required to conduct research are reasonably shared by universities and the government. (aau.edu)
Umbilical cord1
Context1
  • Within this context, research involving stem cells are on the agenda of several academic articles and major newspapers and magazines around the world. (bvsalud.org)
Disease6
  • His company researches and develops cellular treatments for heart disease. (pacatholic.org)
  • In J. St. John (Ed.), Mitochondrial DNA, mitochondria, disease and stem cells (pp. 49-68). (dundee.ac.uk)
  • The unique properties of human stem cells have aroused considerable optimism about their potential as new pathways for alleviating human suffering caused by disease and injury. (edu.au)
  • 2 ), and thus has a significant impact on standards for disease management and conduct of research ( 3 ). (who.int)
  • Research is performed to understand mechanisms involved in regeneration and repair after peripheral nerve injury in both experimental and clinical studies, including rehabilitation, in health and disease. (lu.se)
  • The answers to these questions have implications for risks for sexual transmission and, therefore, embryonic infection, congenital disease, miscarriage, and effects on epidemiologic and transmission models. (cdc.gov)
Support7
  • Why should we support embryonic stem cells research? (oxodocs.com)
  • This is the topic, support stem cell reseach in this paper. (onlinetutors247.com)
  • This reason has convinced some people who otherwise are pro life to nevertheless support embryonic stem-cell research. (blogspot.com)
  • Since 2 years ago, the last Stem Cell bill, public support has surged for stem cells. (ontheissues.org)
  • Some people are calling the bill a back-door attempt to ban embryonic stem cell research - a ban Shortey said he would support, KRMG reported. (go.com)
  • Research dollars are more likely to go to projects that find evidence to support the theory of anthropogenic climate change, not to fund research that treats its theoretical effect. (stephentaylor.ca)
  • Sometimes the association also works to foster community support and promote an environment conducive to innovative research. (who.int)
19981
  • Embryonic stem cell transplants have been an ethical, social, and legal controversy since the first successful transplant of human stem cells in 1998. (ipl.org)