Embryo LossGenes, LethalEmbryo, MammalianFetal DeathEmbryonic DevelopmentGene TargetingGene Expression Regulation, DevelopmentalMice, KnockoutHomozygoteEmbryonic and Fetal DevelopmentHeterozygoteBlastocystMice, Mutant StrainsPhenotypeMice, TransgenicMutationMice, Inbred C57BLGene DeletionPregnancyIn Situ HybridizationIntegrasesEmbryo, NonmammalianMesodermCrosses, GeneticAllelesTranscription FactorsBase SequenceMolecular Sequence DataNuclear ProteinsDNA-Binding ProteinsApoptosisRNA, MessengerEmbryonic Stem CellsStem CellsGenotypeCell DifferentiationSignal TransductionExonsTumor Suppressor ProteinsCells, CulturedCarrier ProteinsAmino Acid SequenceCell ProliferationReverse Transcriptase Polymerase Chain ReactionFibroblastsCell Cycle ProteinsTime FactorsCell LineMammalsMorphogenesisCell DivisionSequence Homology, Amino AcidLarvaTumor Suppressor Protein p53Cell SurvivalChick EmbryoAnimals, Genetically ModifiedCardiovascular AbnormalitiesHomeodomain ProteinsZebrafishHeartDNA PrimersDrosophilaDrosophila melanogasterImmunohistochemistryBody PatterningNervous SystemCloning, MolecularCaenorhabditis elegans ProteinsYolk SacGene ExpressionNeural Tube DefectsCaenorhabditis elegansNeuronsDrosophila ProteinsOrgan SpecificityNerve Tissue ProteinsDNA, ComplementaryGastrulaZebrafish ProteinsMembrane ProteinsAnimals, NewbornGene Expression RegulationZygoteCentral Nervous SystemBrainTissue DistributionBlotting, WesternCell LineageGenes, InsectGene Expression ProfilingProteinsNeural CrestTranscription, GeneticModels, GeneticPlacentaGerm CellsGestational AgeRepressor ProteinsSequence Alignment