• Precursors of inhibitory interneurons transplanted from the medial ganglionic eminence of the ventral embryonic forebrain into the juvenile or adult rodent cortex migrate from the graft site and become dispersed throughout the recipient tissue (shown as small red dots in the transplanted hemisphere in a cross section of the rodent brain, upper left). (sciencemag.org)
  • AMHERST, Mass. - A team of scientists, including University of Massachusetts geneticist Deborah J. Good, has identified a gene which appears to be critical during embryonic development. (umass.edu)
  • Hypermethylation of promoter CpG islands within tumor suppressor genes correlates with gene silencing and the development of cancer. (cellsignal.com)
  • Versican gene expression and quantitative β-GAG immunohistochemistry performed from embryonic day (E) 11.5 to E15.5 showed peak versican expression at E13.5 in the lung and the brain. (washington.edu)
  • In recent years, Kipps and others have become increasingly interested in the role of ROR1 plays in the growth of cancer - and whether the protein might provide new options for stopping development of the disease. (ucsd.edu)
  • Failure of the molecular systems that control development prevents normal embryonic growth, and alterations in these control systems can lead to a wide variety of cancers," explains Kamal Shukla, program director in NSF's division of cellular and molecular biosciences, which funds the research. (bio-medicine.org)
  • Thyroid hormones in growth and development of fish," Comparative Biochemistry and Physiology C , vol. 130, no. 4, pp. 447-459, 2001. (hindawi.com)
  • Vascular endothelial growth factors (VEGFs) control angiogenesis and lymphangiogenesis during development and in pathological conditions. (biologists.org)
  • Later in development, during gastrulation, the three germ layers form, and most cells become more restricted in the types of cells that they can produce. (hhmi.org)
  • They often can be found to have features of embryonic cells. (ucsd.edu)
  • Results published March 9 in the journal Current Biology, however, suggest that competition for the MAPK enzyme among proteins in different pathways influences which signals are sent to cells, establishing a biochemical mode of signal integration that adds a previously unrecognized layer of complexity and control to embryonic development. (princeton.edu)
  • One of the first, and arguably most important, steps in development is the allocation of cells into three germ layers-ectoderm, mesoderm , and endoderm-that give rise to all tissues and organs in the body," explains Mark Mercola, Ph.D., professor and director of Sanford-Burnham's Muscle Development and Regeneration Program in the Sanford Children's Health Research Center. (medicalxpress.com)
  • Versican is a chondroitin sulfate proteoglycan and a component of the extracellular matrix that has previously been shown to have an important role during the embryonic development of many organs. (washington.edu)
  • The goal of this study was to determine the role of NFIB during SMG development. (nih.gov)
  • Serotonin thus plays a role in development before it acts as a neurotransmitter ( 1 - 3 ). (pnas.org)
  • Subsequent work found that ROR1 is expressed at high levels during embryogenesis, during which time it plays an important role in regulating embryonic muscle and skeletal development. (ucsd.edu)
  • In a study published in the journal Genes & Development , Mercola and his team, including postdoctoral researcher Alexandre Colas, Ph.D., and Wesley McKeithan, discovered that microRNAs play an important role in this cell- and germ layer-directing process during development. (medicalxpress.com)
  • This new resource should facilitate the selection of candidate proteins for targeted quantitation and refine systematic genetic network analysis in vertebrate development and biology. (mcponline.org)
  • Another marvelous reflection of creation is the astonishing process of embryonic development, including the way a human being develops in his or her mother s womb. (sounddoctrine.net)
  • Understanding the molecular mechanisms that control normal embryonic development is the first step in developing strategies to prevent these errors, or to repair them when they have gone wrong. (bio-medicine.org)
  • It comes as no surprise that embryonic development is a very carefully orchestrated process-everything has to fall into the right place at the right time. (medicalxpress.com)
  • How does that harmonious interlocking of separate processes come about which makes up the complete process of development? (nobelprize.org)
  • MAPK signaling pathways, or chemical networks that involve the enzyme, are critical for normal development, and defects in these pathways can lead to severe developmental disorders and cancer. (princeton.edu)
  • They say, in effect, 'Look, if you re talking about creation, then surely the Creator must not be very good at it, or else there wouldn t be all those mistakes in human embryonic development. (sounddoctrine.net)
  • That s what we see in human embryonic development. (sounddoctrine.net)
  • MicroRNAs are increasingly recognized as an important part of both normal cellular function and the development of human disease. (medicalxpress.com)
  • New research from Portland State University finds vitamin D, or a lack thereof can trigger or suspend embryonic development in a species of fish. (wn.com)
  • These questions, various answers to which constitute the theories of preformation or epigenesis, were lifted out of the realm of speculation up into that of an exact science when first Wilhelm Roux and then Hans Driesch used experimental methods in their research into development. (nobelprize.org)
  • These results lay the groundwork for further research on polyunsaturated fatty acid metabolism and its various roles in development and disease," Farber said. (carnegiescience.edu)
  • Altogether, the presence of serotonin, its receptors, and transporter during development and the ability of compounds that modulate serotonergic signaling to interfere with development suggest that serotonin functions as a humoral morphogen ( 8 - 10 ). (pnas.org)
  • M. Sjoberg, B. Vennstrom, and D. Forrest, "Thyroid hormone receptors in chick retinal development: differential expression of mRNAs for α and N-terminal variant β receptors," Development , vol. 114, no. 1, pp. 39-47, 1992. (hindawi.com)
  • Our in vivo work clearly establishes for the first time that maternal serotonin production is an important determinant of normal development. (pnas.org)
  • Maternal Serotonin Ensures Normal Development. (pnas.org)
  • University of Manchester and University of North Texas scientists are the first to show that an embryonic living heart can be programmed to survive the effects of a low oxygen environment in later life. (phys.org)
  • It occurs in both animal and plant development, this article addresses the common features among different animals. (phys.org)
  • These data demonstrate that, rather than being dispensable during development, Vegfd plays context-specific indispensable and also compensatory roles during both blood vessel angiogenesis and lymphangiogenesis. (biologists.org)
  • Accumulating in vitro evidence also indicates that serotonin signaling participates in the regulation of development in many animal phyla before the onset of neurogenesis. (pnas.org)