Embryonic cells genetically donor egg cell. Medical search. Frequent questions

Development will ensue normally and after many mitotic divisions, the single cell forms a blastocyst (an early stage embryo with about 100 cells) with an identical genome to the original organism (i.e. a clone). (wikipedia.org)
The resulting cells would be genetically identical to the somatic cell donor, thus avoiding any complications from immune system rejection. (wikipedia.org)
The resulting organism then turns out to be genetically identical to the donor. (payforessay.net)
In another strategy, called therapeutic cloning, the embryo can instead be used to create stem cells that are genetically identical to a patient. (nih.gov)
Before this new study was published, Nature asked another group of researchers to confirm that the stem cells were genetically identical to the donor skin cells. (nih.gov)
As the fertilized egg divides from one cell into two, physicians can separate these two cells and implant each one of them into a woman's uterus to generate two genetically identical children. (jcpa.org)
In sexual reproduction, clones are created when a fertilized egg splits to produce identical (monozygous) twins with identical genomes. (who.int)
Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)
The word "cloning" refers to a variety of procedures that may be used to create biological copies that are genetically identical to the original. (geminigenetics.com)
Asexual reproduction is a natural method used by certain plants, bacteria, and single-celled creatures to create genetically identical offspring, i.e. clones. (geminigenetics.com)
When a fertilised egg separates into two or more embryos with almost identical DNA, these twins are created. (geminigenetics.com)
The twins share common genes with their parents, but are genetically identical to each other. (geminigenetics.com)
This is the most known form of cloning and involves creating a genetically identical replica of a whole organism. (geminigenetics.com)
The resulting embryo is then implanted into a surrogate mother, resulting in the birth of an animal genetically identical to the body cell donor. (geminigenetics.com)
Pet cloning is the process where a genetically identical twin is created of your original animal companion. (geminigenetics.com)
The surrogate mum carries the cloned pet for the gestation period and once ready, gives birth to the clone who will be an identical genetic twin to the original pet whose skin sample was used to make the nucleus of the donor egg cell. (geminigenetics.com)
After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
Cloning occurs naturally in asexual reproduction in plants and animals, and in human reproduction when genetically identical twins are produced. (twig-usa.com)
Embryonic cloning involves separating the cells of an embryo to create several identical embryos. (twig-usa.com)
Clones are genetically identical and occur naturally in asexual reproduction in bacteria and in plants. (twig-usa.com)
Cloning can also occur in human reproduction, when a fertilized egg cell breaks in half, resulting in identical twins. (twig-usa.com)
Molecular tests of artificially differentiated cells invariably show them to be not identical to their natural counterparts (also see below). (independentsciencenews.org)
Snuppy is genetically identical to the donor Afghan hound. (nature.com)
We tested whether the cloned dogs were genetically identical by microsatellite analysis of genomic DNA from the donor Afghan, the cloned dogs and the surrogates (see supplementary information ). (nature.com)
Analysis of eight canine-specific microsatellite loci confirmed that the cloned dogs were genetically identical to their donor dog. (nature.com)
Cloning is the production of living struc-tures genetically identical to their parent struc-ture. (yourarticlelibrary.com)
Cells of a clone are identical genetically, morphologically and physiologically. (yourarticlelibrary.com)
In biology , cloning is the process of producing similar populations of genetically identical individuals that occurs in nature when organisms such as bacteria , insects or plants reproduce asexually . (wikiquote.org)
Reproductive Cloning - Use of a donor cell to create a new human genetically identical to the donor. (schlich.co.uk)
It is a method that involves the production of a group of identical cells or organisms that all derive from a single individual (Grolier 220). (benjaminbarber.org)
The second method of cloning a human involves taking cells from an already existing human being and cloning them, in turn creating other individuals that are identical to that particular person. (benjaminbarber.org)

The egg is now viable and capable of producing an adult organism containing all necessary genetic information from just one parent. (wikipedia.org)
These cells genetically matched the donor organism from which they came. (wikipedia.org)
These cells are deemed to have a pluripotent potential because they have the ability to give rise to all of the tissues found in an adult organism. (wikipedia.org)
The proper definition of cloning is the reproduction of a replicate organism without fertilization or fusion of gonad cells. (payforessay.net)
Stem cell research is, in part, a quest to understand cellular differentiation, the process by which a human being develops from one fertilized cell into a multicellular organism composed of over 200 different cell types - for example muscle, nerve, blood cell, or kidney. (jcpa.org)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
A new organism is created by asexual reproduction using a duplicate of a single cell from the parent organism. (geminigenetics.com)
The process of reproductive cloning involves the nucleus of a somatic (body) cell from a donor organism to be cloned being transferred into an egg cell whose nucleus (genetic material) has been removed. (geminigenetics.com)
No matter how simple or complex an organism is, the cell remains the structurally and functionally basic unit of life (there are even unicellular organisms, like bacteria. (orthodoxwiki.org)
Stem cells are the way the organism generates all the specialized cells needed for development and functioning. (orthodoxwiki.org)
Any of the cells resulted from these divisions can give rise to all the cells needed to make up an adult organism. (orthodoxwiki.org)
Adult stem cells are dispersed in tissues throughout the mature organism and behave very differently depending on the local environment. (orthodoxwiki.org)
These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
1 We fully support this statement concerning the civil rights of all human beings, which applies, of course, to even the most vulnerable among us, including the single-cell human organism, the human embryo immediately reproduced at the beginning of the process of fertilization. (lifeissues.net)
It has been known for over 125 years that fertilization results in the formation of a new genetically unique living single-cell human organism, a human embryo or human being at the single-cell stage. (lifeissues.net)
At the top of the list comes the zygote-a fertilized egg, which of course has the ability to divide and differentiate into all cell types in the body and create a new organism. (thefutureofthings.com)
The first three divisions of the zygote give birth to eight totipotent cells, each of which also has the ability to become an entire organism. (thefutureofthings.com)
XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
… "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)
Totipotency is the ability of a cell to grow into a complete organism. (yourarticlelibrary.com)
DNA is extracted from an organism by breaking its cells, separation of nuclei and rupturing of nuclear envelope. (yourarticlelibrary.com)
The new organism thus produced is genetically distinct from all other human beings and has embarked upon its own distinctive development. (actionlife.org)
This is cloning, a process in which the body cell that donated the replacement nucleus supplies the chromosomes of the new human organism. (actionlife.org)

In genetics and developmental biology, somatic cell nuclear transfer (SCNT) is a laboratory strategy for creating a viable embryo from a body cell and an egg cell. (wikipedia.org)
Stem cells can then be obtained by the destruction of this clone embryo for use in therapeutic cloning or in the case of reproductive cloning the clone embryo is implanted into a host mother for further development and brought to term. (wikipedia.org)
The aim of carrying out this procedure is to obtain pluripotent cells from a cloned embryo. (wikipedia.org)
Embryonic stem cells are undifferentiated cells of an embryo. (wikipedia.org)
The egg then "reprograms" the adult nucleus so that the cell behaves like an embryo but has the genes of the adult cell. (nih.gov)
Since embryonic stem cells have the ability to form virtually any cell type in the body, those taken from a cloned embryo could potentially be used to treat many diseases. (nih.gov)
The predominant bioethical concern arising from this technology is that the blastocyt-stage embryo must be destroyed in the process of isolating and separating the embryonic stem cells from the inner mass region of the pre-embryo. (jcpa.org)
The destruction of the pre-embryo has been the critical issue in the U.S. behind imposing limits on federal government-sponsored research in embryonic stem cells. (jcpa.org)
Many politicians, religious leaders, and bioethicists believe that any destruction of the pre-implanted embryo or fertilized egg is akin to murder. (jcpa.org)
Therapeutic cloning involves the creation of an early-stage embryo (blastocyst) and the removal of stem cells from the developing embryo. (geminigenetics.com)
An electrical impulse is then applied to the egg cell to stimulate it to become an embryo. (geminigenetics.com)
Basically, any of these cells can "act as an embryo. (orthodoxwiki.org)
They have lost the ability to differentiate to all cell types needed for a complete embryo development (up to 14 days post-fertilization). (orthodoxwiki.org)
They are derived from the primordial germ cells, which occur in a specific part of the embryo/fetus called the gonadal ridge. (orthodoxwiki.org)
In a study published today in the journal Cell Stem Cell , researchers discovered it's possible to regenerate human eggs or oocytes-the cellular beginning of an embryo-by making use of genetic material that normally goes to waste. (salk.edu)
The egg is artificially stimulated to divide and behave in a similar way to an embryo fertilised by sperm. (eurostemcell.org)
During the process of harvesting embryotic stem cells, the embryo is destroyed. (healthline.com)
The ill-defined and inaccurate term pre-embryo , which includes the embryonic disc, is said either to end with the appearance of the primitive streak or to include neurulation. (lifeissues.net)
The early mammalian embryo consists of the extra-embryonic cell layers-the trophoblast and a body of cells called the inner cell mass (ICM), which eventually become the embryo proper. (thefutureofthings.com)
A look at natural cloning and the main artificial cloning techniques devised by man, including embryo transplant and fusion cell cloning. (twig-usa.com)
However, the process is still ethically controversial, as researchers first create a human embryo and then destroy it to create stem cells. (bioedge.org)
It creates an embryo only for the purpose of harvesting its cells. (bioedge.org)
There are four avenues - all largely untested at the moment - of creating embryonic stem cell lines without destroying an embryo. (bioedge.org)
The fourth, and most novel idea, is to develop stem cells from genetically altered cells which could never develop into an embryo. (bioedge.org)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
The size of the inner cell mass and the number of stem cells present reflect the developmental potential of the embryo, in that the stem cells form the baby. (sharedjourney.com)
Research advocates attack President Bush for "banning stem cell research," while pro-life advocates lament a Republican administration and Congress that have banned nothing-not embryo destruction, not human cloning, not fetal farming, not genetic engineering. (eppc.org)
That is to say, we risk turning developed cells into developing embryos, and thus risk engaging in the very activities of embryo destruction and human cloning that we seek to avoid. (eppc.org)
Before leaving office, President Clinton sought to get around the existing law without actually changing it, by funding research on embryonic stem cells so long as the actual embryo destruction was paid for with private dollars. (eppc.org)
It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
This mouse egg (top) is being injected with genetic material from an adult cell to ultimately create an embryo - and, eventually, embryonic stem cells. (usf.edu)
They look like the cells in a human embryo - in fact, they're called embryonic stem cells. (usf.edu)
Crucial to embryo production is the availability of oocytes (egg cells) and sperm. (izw-berlin.de)
Normally, the embryo comes into being through sexual conception, in which the female egg cell is fertilized by a male sperm cell. (actionlife.org)

The blastocyst stage is developed by the egg to help create embryonic stem cells from the inner cell mass of the blastocyst. (wikipedia.org)
Fertilization then occurs leading to the development of a blastocyst which then develops into an embryonic cell. (payforessay.net)
The reason for this is that the cells within a blastocyst are not yet differentiated. (payforessay.net)
Most researchers obtain embryonic stem cells from the inner mass of a blastocyst, an embryonic stage when a fertilized egg has divided into 128 cells. (jcpa.org)
The stem cells derived from the inner mass of a blastocyst lack the ability to form a fetus when implanted into a woman, but are self-renewing and can be maintained for long periods of time in the laboratory as undifferentiated stem cells. (jcpa.org)
In the interior of the blastocyst, there is a cluster of about 30 cells called the inner cell mass. (orthodoxwiki.org)
The cells that form the inner cell mass of the blastocyst are called pluripotent stem cells . (orthodoxwiki.org)
Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
I had 2pn frozen embryos (donor egg) cultured for 5 days and transferred a grade 2 blastocyst and a 3bb blastocyst. (sharedjourney.com)
As the blastocyst cavity expands, the inner cell mass containing the stem cells becomes visible and may be graded based on the size and number of stem cells present (A is good, D is bad). (sharedjourney.com)
When donated eggs are used, 50-60% of the embryos should make it to the blastocyst stage with majority be of top quality. (sharedjourney.com)
Athough a first time donor may look good on paper, E2 levels and U/S, the quality of the eggs cannot be ascertained until the eggs are fertilized and the embryos cultured to the blastocyst stage. (sharedjourney.com)
Usually all plants are totipotent but in animals only fertilized egg (zygote) and stem cells in the embryonic blastocyst are totipotent. (yourarticlelibrary.com)
[ 2 ] This technique has evolved throughout the years and is now largely performed by biopsy of the blastocyst trophectoderm cells with analysis using techniques such as next-generation sequencing (NGS) and comparative genomic hybridization (CGH) to test for aneuploidy. (medscape.com)

this approach has been championed as an answer to the many issues concerning embryonic stem cells (ESCs) and the destruction of viable embryos for medical use, though questions remain on how homologous the two cell types truly are. (wikipedia.org)
Controversy surrounds human ESC work due to the destruction of viable human embryos, leading scientists to seek alternative methods of obtaining pluripotent stem cells, SCNT is one such method. (wikipedia.org)
Researchers reported in Nature on November 22, 2007, that they successfully isolated 2 embryonic stem cell lines from cloned embryos made using cells from the skin of an adult rhesus macaque. (nih.gov)
Stem cells originating in human embryos can be categorized as either embryonic stem cells or embryonic germ cells . (orthodoxwiki.org)
In Vitro Fertilization - some of the embryos used in human stem cells research were initially created for infertility purposes through in vitro fertilization procedures. (orthodoxwiki.org)
Embryonic stem cells come from human embryos that are three to five days old. (healthline.com)
In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
The researcher claimed he had created stem cell lines from cloned human embryos. (asianews.it)
Interest in using stem cells from cloned human embryos has revived after success by scientists in the United States and Korea. (bioedge.org)
The chief opponents of embryonic stem cell research in the US, Republicans and the Catholic Church, are beginning to back alternative techniques of creating the cells for research and therapies which do not destroy embryos. (bioedge.org)
According to one of its champions, Professor Robert George, of Princeton University, "we would reasonably expect to obtain precisely the type of stem cells desired by advocates of embryonic stem-cell research, without ever creating or killing embryos. (bioedge.org)
The cells used would not be embryos and would at no point go through an embryonic stage. (bioedge.org)
Chinese scientists have successfully created chimeric embryos containing a combination of human and pig cells. (bioedge.org)
The potential use of embryonic stem cells (ESCs) for cell replacement therapies is limited by ethical concerns and the technical hurdles associated with their isolation from human embryos. (biomedcentral.com)
Similar to embryonic stem cells (ESCs), hpSCs are pluripotent cells that can be reproduced into any type of cell within the human body without using or destroying the viable human embryos. (pharmaceutical-technology.com)
Citizens disagree about whether we should destroy human embryos for their stem cells-and if so, which embryos, with whose money, under what regulatory guidelines. (eppc.org)
The holy grail of regenerative medicine-whatever one's ethical beliefs about destroying embryos-is to "reprogram" regular cells from one's own body so that individuals can be the source of their own rejection-proof therapies. (eppc.org)
But we need to proceed carefully, recognizing that we are gaining new powers over human origins even when we do not use human embryos, and recognizing the danger of blurring the line between cellular parts and embryonic wholes. (eppc.org)
Far more controversial-and for good reason-are stem cells derived from destroyed human embryos. (eppc.org)
Moreover, most early-stage embryos that are produced naturally (that is, through the union of egg and sperm resulting from sexual intercourse) fail to implant and are therefore wasted or destroyed. (wikiquote.org)
Animals (or embryos) composed of cells of different genetic origin. (nationalacademies.org)
Cell lines derived from early embryos that have the potential to differentiate into all types of somatic cells as well as to form germ line cells, and hence whole animals, when injected into early embryos. (nationalacademies.org)
Stem cell technologies have been dogged by controversy because of objections over the morality of sacrificing human embryos to produce the first human embryonic stem cell lines. (schlich.co.uk)
In the ongoing debate about cloning human embryos for research, and about destroying them in order to harvest their stem cells, it is important to keep some basic facts in mind. (actionlife.org)
They attempted to create seventeen human embryos in a laboratory dish and when it had grown enough, separated them into forty-eight individual cells. (benjaminbarber.org)
Two of the separated cells survived for a few days in the lab developed into new human embryos smaller than the head of a pin and consisting of thirty-two cells each (Brownlee 24). (benjaminbarber.org)

Embryonic stem cells are known as pluripotent stem cells. (healthline.com)
Scientists have recently discovered how to turn adult stem cells into pluripotent stem cells. (healthline.com)
These new types of cells are called induced pluripotent stem cells (iPSCs). (healthline.com)
However, some features of these cells are said to be superior to induced pluripotent stem cells, their main rival at this point. (bioedge.org)
Derivation of autologous induced pluripotent stem cells (iPSCs) through direct reprogramming of easily accessible somatic cells holds the potential to transform the field of regenerative medicine. (biomedcentral.com)
Here, we summarize current reprogramming methodologies with a focus on the production of transgene-free or genetically unmanipulated iPSCs and highlight important technical details that ultimately may influence the biological properties of pluripotent stem cells. (biomedcentral.com)
In 2006, a major breakthrough was reported in Japan by Takahashi and Yamanaka, who described the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts via over expression of defined transcription factors [ 2 ]. (biomedcentral.com)
Unlike induced pluripotent stem cells (iPSs), hPSCs do not manipulate the gene expression process back to a less differentiated stage, thereby avoiding the regulatory, ethical and safety obstacles. (pharmaceutical-technology.com)
The somatic cells are modified with extra DNA or RNA, or by exposing them to proteins or drugs, which has the effect of turning some of them into induced pluripotent stem cells (iPSCs). (independentsciencenews.org)
And the other technique, which produces " induced pluripotent stem cells ," skips the step that requires a human egg cell, so some people find it less fraught, ethically. (usf.edu)
In its race to advance assisted reproduction and stem cell associated technologies to save the northern white rhinoceros from extinction, the BioRescue consortium announces a major breakthrough: the creation of primordial germ cell-like cells (PGCLSs) from induced pluripotent stem cells of the northern white rhino Nabire. (izw-berlin.de)
With stem cell associated techniques (SCAT) the BioRescue scientists aim to overcome this bottleneck: By using stored and preserved tissue of rhino skin it should be possible in principle to create induced pluripotent stem cells (iPCSs), primordial germ cells and finally artificial gametes. (izw-berlin.de)
According to their most recent paper published in the journal "Science Advances", the team has now successfully cultivated primordial germ cells (PGCs) - the precursors of eggs and sperm - from embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). (izw-berlin.de)
They established culture systems for the southern white rhino, for which embryonic stem cells are available, and the northern white rhino, for which they used induced pluripotent stem cells derived from tissue samples. (izw-berlin.de)
In the case of the white rhinoceroses, Hayashi is working in close cooperation within BioRescue with Sebastian Diecke's Pluripotent Stem Cells Platform at the Max Delbrück Center and with reproduction experts Thomas Hildebrandt from Leibniz-IZW, both of them last authors of the paper, and Cesare Galli from Avantea. (izw-berlin.de)
Because PGCs are the founder population for gametes, this accomplishment paves a way to produce functional gametes from induced pluripotent stem cells from northern white rhinos which will contribute to the effort to rewind their extinction. (izw-berlin.de)
The greatest hope rests on the potential of pluripotent stem cells, which can become nearly any kind of cell in the body. (pharmaceuticalintelligence.com)
One method of creating pluripotent stem cells is called somatic cell nuclear transfer, and involves taking the nucleus of an adult cell and injecting it into an egg cell from which the nucleus has been removed. (pharmaceuticalintelligence.com)
Although many stem cell researchers are focused on a different method of creating pluripotent stem cells, called induced pluripotent stem cells, there may be some applications for which SCNT-derived pluripotent cells are better suited. (pharmaceuticalintelligence.com)
Therapeutic Cloning - Use of a donor cell to create pluripotent stem cells suitable for growing tissues for implantation into the donor or other patient. (schlich.co.uk)

The first is that great old standard, "sexual" reproduction, in which sperm meets egg. (cbc-network.org)
The gonadal ridge normally develops into mature gametes (eggs and sperm). (orthodoxwiki.org)
Should there be a 'dead donor rule' for sperm donation? (bioedge.org)
egg and sperm). (biotechfront.com)
On the other hand, in germline gene therapy , the egg and sperm cells of the parents are altered to be passed on to their offspring. (biotechfront.com)
Research on the manufacture of egg-like and sperm-like cells for the purpose of producing laboratory-crafted human children is proceeding rapidly. (independentsciencenews.org)
The objective is to turn ordinary body cells of prospective parents into artificial eggs and sperm. (independentsciencenews.org)
Though ostensibly developed to facilitate reproduction in individuals for whom this capability is impaired or unavailable, the use of laboratory produced eggs and sperm represent an opening for the routine production and commercialization of "designer babies. (independentsciencenews.org)
Researchers refer to creating eggs and sperm (gametes) in the laboratory as in vitro gametogenesis or IVG. (independentsciencenews.org)
The iPSCs are next exposed to other biomolecules or drugs, to convert them into cells resembling the specialized cells of the body, such as eggs or sperm. (independentsciencenews.org)
Promoters suggest that IVG would make it possible for medically infertile people to have biologically related children without seeking authentic eggs or sperm from a donor. (independentsciencenews.org)
[3] The technology would also make it possible for a fertile person wanting to become a single parent of a biologically related child to do so without gametes (egg or sperm) donated by an identifiable second person (solo IVG). (independentsciencenews.org)
that is, a person from whom both synthetic eggs and sperm are derived. (independentsciencenews.org)
Now there is one last step to master for the production of artificial rhino gametes (eggs and sperm) from preserved tissue. (izw-berlin.de)
Female Fatu is the only donor of natural oocytes left and frozen sperm is available to the program from only four males - and some of these males are closely related to Fatu. (izw-berlin.de)
In sexually reproducing organisms such as humans, rhinos or mice, primordial germ cells (PGCs) are embryonic precursors of sperm and eggs that pass on genetic and epigenetic information from one generation to the next. (izw-berlin.de)
Homologous recombination also produces new combinations of DNA sequences during meiosis, the process by which eukaryotes make gamete cells, such as sperm and egg in animals. (oldfield.info)
In sexual reproduction the new individual gets half of its chromosomes from the nucleus of the sperm cell and half from the nucleus of the egg cell. (actionlife.org)
One of these techniques stages the encounter of sperm with egg in a laboratory dish rather than in a woman's body. (actionlife.org)
Xenograft-derived sperm where then injected into donor eggs and implanted into a total of 53 female surrogate monkeys. (asianscientist.com)
In the wild type donor group, we can get mature sperm in two years. (asianscientist.com)
It involves taking an egg from the woman and taking sperm from the man. (benjaminbarber.org)

The stem cells, the researchers showed, could turn into heart or nerve cells in the laboratory, and had other characteristics of established embryonic stem cell lines. (nih.gov)

In the case of asexually creating a human, the biotechnologist removes the nucleus from a mature human egg (an oocyte). (cbc-network.org)
The technique consists of taking an denucleated oocyte (egg cell) and implanting a donor nucleus from a somatic (body) cell. (wikipedia.org)
The first being a female gamete, known as the ovum (egg/oocyte). (wikipedia.org)
In the study, scientists successfully transplanted a polar body from a woman's developing oocyte into the cytoplasm of a donor oocyte stripped of its nucleus. (salk.edu)
By rescuing polar bodies that would otherwise simply bud off the developing oocyte, researchers were able to form additional oocytes genetically related to the mother through nuclear transfer. (salk.edu)
This produces either heterozygous human parthenogenetic stem cell lines that can be precisely HLA-matched or stem cell lines histocompatible with the oocyte donors or HLA homozygous hPSC that are histocompatible with the major segments of human population. (pharmaceutical-technology.com)
For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)

The primary cloning technique is called "somatic cell nuclear transfer" (SCNT). (cbc-network.org)
The bill purports to promote stem-cell research, while outlawing the cloning of a human being. (cbc-network.org)
While stem-cell research holds enormous potential for treating or even curing some diseases, the cloning of a human being is morally and ethically unacceptable…Any attempt to clone a human being is in direct conflict with the public policies of this state. (cbc-network.org)
Somatic cell nuclear transfer is a technique for cloning in which the nucleus of a somatic cell is transferred to the cytoplasm of an enucleated egg. (wikipedia.org)
Cloning entails taking the nucleus - the compartment that contains the DNA - from an adult cell and putting it into an egg from which the original nucleus has been removed. (nih.gov)
Numerous biological components, including genes, cells, tissues, and even complete creatures like sheep, have been cloned by researchers, and now cat, dog and equine cloning is widely and reliably available via international companies such as our partner, ViaGen Pets & Equine. (geminigenetics.com)
Therapeutic cloning refers to the production of embryonic stem cells for medicinal reasons, for example regenerative medicine and tissue replacement. (geminigenetics.com)
What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
This form of cloning is unrelated to stem cell research. (eurostemcell.org)
To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
Although attempts have not yet been made to create a therapeutic transplant from embryonic stem cells, the methods have been developed to allow the creation of functional, mature cells using human cell cloning technology. (news-medical.net)
Retrieved on December 04, 2023 from https://www.news-medical.net/life-sciences/Cloning-Human-Cells.aspx. (news-medical.net)
Lee Byeong-chun and Kang Seung-keun were accused of faking the outcome of studies on cloning human stem cells while working with Hwang. (asianews.it)
Artificial cloning techniques include: embryonic cloning and fusion cell cloning. (twig-usa.com)
Fusion cell cloning involves removing the nucleus of an egg and replacing this with a cell nucleus of a donor. (twig-usa.com)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)
Over the past few years, the debate over stem cells and cloning has grown both more complex and more profound. (eppc.org)
But if we are to make wise policy the stem cell/cloning arena, we need to step back, sort out the various scientific alternatives and moral issues, and search for a way forward that all citizens can embrace. (eppc.org)
To this end, we offer a detailed analysis of the stem cell/cloning question-where is the science, what are the political alternatives, and what moral obligations should guide us? (eppc.org)
Cloning is of several types-cell cloning, gene cloning, microbial cloning, plant cloning and animal cloning. (yourarticlelibrary.com)
Cell cloning is the formation of multiple copies of the same cell. (yourarticlelibrary.com)
Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
What we show for the first time is that you can actually take skin cells, from a middle-aged 35-year-old male, but also from an elderly, 75-year-old male" and use the DNA from those cells in this cloning process, Lanza says. (usf.edu)
But he says this does mean we could be getting closer to being able to go beyond cloned cell lines to cloning an entire human being. (usf.edu)

In addition, as the genetic identity of the donor egg from which the ESCs are derived most likely will differ from that of potential recipients, patients who receive ESC-derived cells or tissues may face the same complications that result from organ transplantation (for example, immunorejection, graft-versus-host disease, and need for immunosuppression). (biomedcentral.com)

Most mCG methylation occurs during early embryonic development, around the time that a fertilized egg implants into the womb. (spectrumnews.org)
We described the early embryonic development of the loach, Misgurnus anguillicaudatus , based on morphological features and gene expression. (bioone.org)

The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)
The stem cell facility will produce human parthenogenic stem cells (hpSCs) that are derived from parthenogenetically induced human oocytes. (pharmaceutical-technology.com)
The HLA genotypes of stem cells obtained from such oocytes are heterozygous and are genetically cloned to the donors. (pharmaceutical-technology.com)
Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)

HumanPass Wednesday confirmed fingerprinting traces of Snuppy, Hwang's canine clone, matched those of its somatic cell donor, an Afghan hound named Tai, while they demonstrated disparate mitochondrial genotypes. (blogspot.com)

However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
a , Snuppy, the first cloned dog, at 67 days after birth (right), with the three-year-old male Afghan hound (left) whose somatic skin cells were used to clone him. (nature.com)
Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
The resulting egg was implanted in the womb of a third sheep, and the result was Dolly, the first clone of a mammal. (usf.edu)
is a British developmental biologist who was the first to use nuclear transfer of differentiated adult cells to generate a mammalian clone, a Finn Dorset sheep named Dolly, born in 1996. (mathisfunforum.com)

A potential use of stem cells genetically matched to a patient would be to create cell lines that have genes linked to a patient's particular disease. (wikipedia.org)
For example, if a person with Parkinson's disease donated their somatic cells, the stem cells resulting from SCNT would have genes that contribute to Parkinson's disease. (wikipedia.org)
Two separate research teams have figured out how to "reprogram" cells with just a handful of genes to give them the characteristics of embryonic stem cells. (nih.gov)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
This was believed to be due to an inability to activate certain embryonic genes. (news-medical.net)
Clearly, methyl groups play a crucial role in determining which genes are expressed in a given cell at a given time. (spectrumnews.org)
Ideally he would like to screen millions of adults and choose just a hundred or so whose genes would make them good DNA donors. (usf.edu)
He'd like to see a library of cells created with those carefully chosen genes. (usf.edu)
Insulin mediates the mRNA expression of cell cycle-, apoptosis-, and ferroptosis-related genes. (bvsalud.org)

After the somatic cell transfers, the cytoplasmic factors affect the nucleus to become a zygote. (wikipedia.org)
After fertilization, the zygote (fertilized egg) divides several times. (orthodoxwiki.org)
This cell is called a zygote, or a fertilized egg. (healthline.com)
The zygote divides into two cells, then four cells, and so on. (healthline.com)
Early developmental staging from the zygote stage to the gastrula is a basic step for studying embryonic development and biotechnology. (bioone.org)
Every human being begins as a single-cell zygote, grows through the embryonic stage, then the fetal stage, is born and develops through infancy, through childhood, and through adulthood, until death. (actionlife.org)
The egg is then stimulated by an electrical charge, creating a living human zygote. (actionlife.org)

It is the policy of Washington state that research involving the derivation and use of human embryonic stem cells, human embryonic germ cells, and human adult stem cells from any source, including somatic cell nuclear transplantation , is permitted upon full consideration of the ethical and medical implications of this research. (cbc-network.org)
Embryonic germ cells share many of the characteristics of the embryonic stem cells but differ in significant ways. (orthodoxwiki.org)
Germ cells do not proliferate as long as stem sells. (orthodoxwiki.org)
Under certain conditions, germ cells do differentiate into specialized cells. (orthodoxwiki.org)
Germ cells and stem cells also differ with respect to their growth characteristics in vitro and their behavior in vivo. (orthodoxwiki.org)
The scientists relied on knowledge from the mouse model: In 2016, Katsuhiko Hayashi and his team managed to create primordial germ cell-like cells and finally germ cells from mice that were fertilised in the lab and resulted in healthy offspring being born. (izw-berlin.de)
Primordial germ cells (PGCs) are essential for the genetic modification, resource conservation, and recovery of endangered breeds in chickens and need to remain viable and proliferative in vitro. (bvsalud.org)

These cells are called totipotent stem cells . (orthodoxwiki.org)

The process of somatic cell nuclear transfer involves two different cells. (wikipedia.org)
Somatic cell nuclear transplantation has become a focus of study in stem cell research. (wikipedia.org)
In the United States, scientists at the Harvard Stem Cell Institute, the University of California San Francisco, the Oregon Health & Science University, Stemagen (La Jolla, CA) and possibly Advanced Cell Technology are currently researching a technique to use somatic cell nuclear transfer to produce embryonic stem cells. (wikipedia.org)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
Hwang's stem cells should have been found to be nuclear transferred embryonic stem cells from patients' skin cells. (blogspot.com)
For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
Although exciting results have been achieved by means of somatic cell nuclear transfer, cell fusion, and culture-induced reprogramming [ 1 ], these procedures are technically demanding and inefficient and therefore unlikely to become a common approach for producing patient-specific pluripotent cells. (biomedcentral.com)
Figure 1: Dog cloned by somatic-cell nuclear transfer. (nature.com)
Eighteen years ago, scientists in Scotland took the nuclear DNA from the cell of an adult sheep and put it into another sheep's egg cell that had been emptied of its own nucleus. (usf.edu)
Writing in the journal Cell Stem Cell , they say they started with nuclear DNA extracted from the skin cells of a middle-age man and injected it into human eggs donated by four women. (usf.edu)
As with Dolly, the women's nuclear DNA had been removed from these eggs before the man's DNA was injected. (usf.edu)
Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to an international study in mice by researchers at the Stanford University, MIT and colleagues in Germany and England. (pharmaceuticalintelligence.com)

To create iPSCs, scientists genetically reprogram the adult stem cells so they behave like embryonic stem cells. (healthline.com)

For example, scientists have not yet found a way of effectively splitting the telomeres during cell division. (payforessay.net)
This policy is similar to that of other countries, including Israel, where scientists are funded by Government to study embryonic stem cells despite the aforementioned bioethical issue. (jcpa.org)
Since stem cells have the ability to turn into various other types of cells, scientists believe that they can be useful for treating and understanding diseases. (healthline.com)
Scientists are hoping that the cells can be made from someone's own skin to treat a disease. (healthline.com)
While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)
Scientists are unlikely to rush into creating human embryonic stem cell lines. (bioedge.org)
Most stem cell scientists are sceptical of the largely theoretical proposal, but Dr William Hurlbut, of Stanford University, has won over his colleagues on the President's Council on Bioethics. (bioedge.org)
Dr Hurlbut has been lobbying hard for his proposals, despite the scorn of many stem cell scientists and quizzical looks by some of his usual allies. (bioedge.org)
ISCO will simultaneously partner with leading scientists across the world to showcase the therapeutic applicability and the potential advantages of hPSC over other stem cells. (pharmaceutical-technology.com)
Long before the controversy emerged over human embryonic stem cells, scientists and doctors began using first-generation stem cells from adult bone marrow. (eppc.org)
But they are also less equipped to produce every cell type of the body and less able to reproduce themselves indefinitely, which makes them less appealing to scientists interested in basic research. (eppc.org)
In July 2005, for example, scientists announced that they had engineered adult mouse stem cells into usable mouse eggs, a technique that might one day allow for the creation of human eggs from ordinary human cells. (eppc.org)
Not too long ago scientists managed to produce stem cells from adult cells, called induced pluripotent cells (iPSC's). (myassignmentwriters.org)
So ideally scientists would like to be able to extract DNA from the cells of older people - not just cells from infants - to create therapies for adult diseases. (usf.edu)
In the 18 years since researchers cloned a sheep, scientists have found another way to produce cloned human cell lines. (usf.edu)
In principle, scientists could produce a series of cell lines that would allow a close match for the majority of would-be cell recipients - just as transplant surgeons currently seek a close match for organ donors. (usf.edu)
When scientists at the Oregon Health and Science University announced success in performing SCNT with human cells last year, it reignited interest in eventually using the technique for human therapies. (pharmaceuticalintelligence.com)
In the future, scientists might also lessen the immune reaction by using eggs from someone who is genetically similar to the recipient, such as a mother or sister. (pharmaceuticalintelligence.com)

This gives them the ability to create patient specific pluripotent cells, which could then be used in therapies or disease research. (wikipedia.org)
These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
Ideally, iPSC-based therapies in the future will rely on the isolation of skin fibroblasts or keratinocytes, their reprogramming into iPSCs, and the correction of the genetic defect followed by differentiation into the desired cell type and transplantation. (biomedcentral.com)
Stem cell therapies hold vast potential for repairing organs and treating disease. (pharmaceuticalintelligence.com)
We now see a patent landscape where stem cell technologies and related therapies can, with very few exceptions, be protected via patents, provided the appropriate form of claim wording is used. (schlich.co.uk)
Stem cell technologies promise to be the next transformative medical technology offering therapies for conditions and diseases that are currently beyond medical science by creating replacement or supplementary tissues for a patient. (schlich.co.uk)

After being free from human interference and the addition of new cattle for over 1000 years, this UK Native breed are considered so genetically similar that they are in fact, genetic clones of each other. (geminigenetics.com)
With the help of micropipette, single cells are added to fresh culture media for multiplication and formation of cell clones. (yourarticlelibrary.com)

This therapy targets either the somatic cells (i.e., body) or the gametes (ie. (biotechfront.com)
As of October 1, 18-year-olds in the United Kingdom conceived with donor gametes will be able to find out who. (bioedge.org)
These cells are not those that evolved to produce gametes during embryonic development. (independentsciencenews.org)
The technology, should it find its way into fertility clinics, may reduce the number of donor gametes that are necessary, but it is likely to vastly increase the need for women to serve as surrogates, especially for same-sex males seeking to reproduce genetically, unless the creation of artificial wombs, currently an actively researched prospect, becomes a reality. (independentsciencenews.org)

Another application of SCNT stem cell research is using the patient specific stem cell lines to generate tissues or even organs for transplant into the specific patient. (wikipedia.org)
Cells of the same type make tissues, and tissues make organs. (orthodoxwiki.org)
In some adult tissues, such as bone marrow, muscle, and brain, discrete populations of adult stem cells generate replacement cells. (orthodoxwiki.org)
Adult stem cells give the body its ability to repair and replace the cells and tissues of some organs. (orthodoxwiki.org)
Dec. 29, 2005 -- South Korean laboratories used by scientist Hwang Woo Suk no longer have any stem cells created from patients' tissues, the result of the researcher's landmark May 2005 paper, the Seoul National University said. (blogspot.com)
These stem cells come from developed organs and tissues in the body. (healthline.com)
In addition to their ability to supply cells at the turnover rate of their respective tissues, they can be stimulated to repair injured tissue caused by liver damage, skin abrasions and blood loss. (thefutureofthings.com)
The ability of our body to regenerate some of its tissues is largely owed to the reserves of adult stem cells. (thefutureofthings.com)
Today, we can derive stem cells from a range of adult and newborn tissues: liver cells, kidney cells, brain cells, fat cells, and umbilical cord blood. (eppc.org)
Transplantation of cells, tissues, or organs from another member of the same species. (nationalacademies.org)
The hope has been that this would eliminate the problem of the patient's immune system attacking the pluripotent cells as foreign tissue, which is a problem with most organs and tissues when they are transplanted from one patient to another. (pharmaceuticalintelligence.com)
reagents made using a patient's own cells used to regenerate disease or damaged tissues 14,15 , once the stuff of science fiction, may become science fact. (schlich.co.uk)

The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
This research informs the medical community of the margin of safety that would be required if, in the distant future, researchers need to use SCNT to create pluripotent cells to treat someone. (pharmaceuticalintelligence.com)

I-SceI) to cut chromosomes for genetic engineering of mammalian cells, where non-homologous recombination is more common than in yeast. (oldfield.info)

The genetic material of the donor egg cell is removed and discarded, leaving it 'deprogrammed. (wikipedia.org)
The DNA within the skin sample is cultured and inserted into a donor egg cell whose nucleus (genetic material) has been removed. (geminigenetics.com)
This DNA comes from small cells called polar bodies that form off of eggs and contain the same genetic material as in a woman's egg nucleus. (salk.edu)
They repeated the process - this time starting with the genetic material extracted from the skin cells of a much older man. (usf.edu)

Meanwhile, the ability of the mature egg to transform and begin embryonic development remains fully potent. (cbc-network.org)
Stem cells are naturally occurring in the human body (and other living organisms) at all levels of development. (orthodoxwiki.org)
As embryonic development proceeds, stem cells lose their pluripotency. (orthodoxwiki.org)
Normally, polar bodies disintegrate and disappear during egg development," said co-first author Hong Ma, MD, PhD, with OHSU's Center for Embryonic Cell and Gene Therapy. (salk.edu)
In 1942, the Carnegie Stages of Early Human Embryonic Development were instituted at the National Museum of Health and Medicine in Washington, D.C. 4 The Carnegie Stages of Early Human Development are the basis for the Nomina Embryologica which was part of the larger Nomina Anatomica for decades until 1989. (lifeissues.net)
see at cargnegiescience.edu from the Carnegie Stages of Early Human Embryonic Development , Stage 1. (americanrtl.org)
We have also seen this kind of substandard development in our donor program (see footnote). (sharedjourney.com)
There are not enough stem cells in the low grade blastocysts to continue development. (sharedjourney.com)
The embryonic development of the loach resembled that of the zebrafish in terms of morphological change and gene expression. (bioone.org)
Thus, the testis xenografting method may facilitate the development of genetically modified monkey models. (asianscientist.com)
Cell competition is a process that compares the relative fitness of progenitor cells, resulting in winners, which contribute further to development, and losers, which are excluded, and is likely a universal quality control process that contributes to the fitness of an individual. (bvsalud.org)

All humans start out as only one cell. (healthline.com)
In rodents, and even in some preliminary trials in humans, human embryonic stem cells have been shown to bridge gaps in spinal cord injuries , allowing restoration of motor functions. (thefutureofthings.com)
It also means that finally getting the sheep technology to work with cells from adult humans may not turn out to be a turning point for this technology, after all. (usf.edu)

Physicians could also extract DNA from the person who is going to receive the cellular transplant - creating a patient-specific treatment - though that would end up being far more expensive than drawing from a library of ready-made cells. (usf.edu)

In human SCNT experiments, these eggs are obtained through consenting donors, utilizing ovarian stimulation. (wikipedia.org)
Only a handful of the labs in the world are currently using SCNT techniques in human stem cell research. (wikipedia.org)
Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
The promise of the SCNT method is that the nucleus of a patient's skin cell, for example, could be used to create pluripotent cells that might be able to repair a part of that patient's body. (pharmaceuticalintelligence.com)
One attraction of SCNT has always been that the genetic identity of the new pluripotent cell would be the same as the patient's, since the transplanted nucleus carries the patient's DNA. (pharmaceuticalintelligence.com)
Stanford University have raised the possibility in the past that the immune system of a patient who received SCNT-derived cells might still react against the cells' mitochondria, which act as the energy factories for the cell and have their own DNA. (pharmaceuticalintelligence.com)
This reaction could occur because cells created through SCNT contain mitochondria from the egg donor and not from the patient, and therefore could still look like foreign tissue to the recipient's immune system. (pharmaceuticalintelligence.com)
When transplanted back into the nucleus donor strain, the cells were rejected although there were only two single nucleotide substitutions in the mitochondrial DNA of these SCNT-derived cells compared to that of the nucleus donor. (pharmaceuticalintelligence.com)
The immunological reactions reported in the new paper will be a consideration if clinicians ever use SCNT-derived stem cells in human therapy, but such reactions should not prevent their use. (pharmaceuticalintelligence.com)

The nucleus of a body cell from the DNA donor is removed, and put into the place formerly occupied by the egg's nucleus. (cbc-network.org)
The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)

The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)

In the fetus, stem cells in developing tissue give rise to the multiple specialized cell types that make up the human body. (orthodoxwiki.org)
In adults, the remaining stem cells only differentiate into cell types specific to the tissue in which they reside (some recent studies seem to prove the contrary. (orthodoxwiki.org)
Adult stem cells are rare, and their origin in mature tissue is not yet completely understood. (orthodoxwiki.org)
Some recent studies focus on the plasticity of the adult stem cells, which is the ability to differentiate in specialized cells of another tissue. (orthodoxwiki.org)
This means they can potentially produce new cells for any organ or tissue. (healthline.com)
Plant tissue can be similarly taken in liquid nutrient medium and shaken mechanically when cells separate. (yourarticlelibrary.com)
and altering cell and tissue characteristics for biomedical research and manufacturing. (nationalacademies.org)
If there are intact cells in this tissue they have been 'stored' frozen. (wikiquote.org)
Using two juvenile monkey donors-one expressing GFP and one wild type control-Sun and his team grafted small pieces of testicular tissue onto the backs of castrated male nude mouse recipients. (asianscientist.com)

While there is a great deal published on the potential medical applications of stem cell research to treat or cure diseases such as diabetes, Alzheimer's disease, Parkinson's disease, cancer, and heart disease, much less has been published on the future impact of stem cell research in reproductive medicine. (jcpa.org)
Embryonic stem cells (ESC's) are said to hold the potential to treat and cure many disorders like diabetes and Parkinson's disease. (myassignmentwriters.org)

The disease specific stem cell lines could then be studied in order to better understand the condition. (wikipedia.org)
The team that isolated the embryonic stem cell lines was led by Dr. Shoukhrat Mitalipov at Oregon Health and Science University in Portland. (nih.gov)
Only two of Hwang's 11 claimed stem-cell lines existed when he submitted his 2005 paper to the journal, Science, the university said on Dec. 23. (blogspot.com)
Although it was only possible to examine a limited number of lines, from the point of view of epigenomic profiles, the quality of polar body-derived embryonic cells looks quite promising," says co-senior author Joseph Ecker , PhD, Salk professor and director of the Genomic Analysis Laboratory. (salk.edu)
One group from CHA University in Seoul reported in Cell Stem Cell in April that it had managed to use cell nuclei from two men, aged 35 and 75, to create embryonic stem cell lines. (bioedge.org)
There have been many false dawns in the field of embryonic stem cell research, but these results seem to confirm that it is possible to use adult cells to create genetically matched stem cell lines. (bioedge.org)

Somatic cells from a donor are extracted, and the nucleus is fused with that of a host egg using in vitro fertilization. (payforessay.net)
The stem cells in storage at Hwang's laboratories at the university were all derived from the fertility clinic MizMedi's blastocysts, which were generated by in vitro fertilization . (blogspot.com)
This is potentially a way to double the number of eggs we're able to get from one session of in vitro fertilization. (salk.edu)
We hope that by doing this, we can double the number of patient eggs available for in vitro fertilization. (salk.edu)
Embryonic life commences with fertilization, and hence the beginning of that process may be taken as the point de depart of stage 1 . (americanrtl.org)

In addition, specific proteins or biological substances can be added to these stem cell cultures to transform them in the laboratory into a large variety of specialized cell types, such as nerve, liver, muscle, bone, and blood cells. (jcpa.org)

The university has been conducting a probe on Hwang and his research since Dec. 16, including genetic tests on stem cells being stored at the laboratories. (blogspot.com)

This ability allows stem cells to create any cell type, which could then be transplanted to replace damaged or destroyed cells. (wikipedia.org)
However, by the time the fertilized egg divides into 8 or 16 cells something changes and each respective cell, if separated, no longer has the potential to create a fetus. (jcpa.org)
Dermal fibroblasts were taken from a 35-year old male and a 75-year-old male and used to create embryonic stem cells. (news-medical.net)
Last May, the House of Representatives passed a bill to create a cord blood stem cell bank, legislation that is likely to become law with virtually unanimous support. (eppc.org)
They injected it into 77 human egg cells, and from all those attempts, managed to create two viable cells that contained DNA from one or the other man. (usf.edu)
Cell competition also has pathological consequences, and can create super-competitor cells responsible for tumor progression. (bvsalud.org)

While both types of stem cells are very important for biomedical research, the use of embryonic stem cells raises most of the bioethical issues. (orthodoxwiki.org)
If animal trials show the technique to work as planned, and the eggs needed for the technique can be obtained in an ethical manner, it could provide a morally acceptable way to pursue biomedical research with these cells," says Richard Doerflinger, a spokesman for the US Catholic bishops. (bioedge.org)

In this study, PGCs collected from Rugao yellow chicken embryonic eggs at Day 5.5 were cultured in media containing 0, 5, 10, 20, 50, and 100 µg/mL insulin. (bvsalud.org)
The results showed that insulin regulates cell proliferation in PGCs in a dose-dependent way, with an optimal dose of 10 µg/mL. (bvsalud.org)
Collectively, this study demonstrates that insulin reduces apoptosis and ferroptosis and enhances cell proliferation in a dose-dependent manner via the PI3K-AKT-mTOR signaling pathway in PGCs, providing a new addition to the theory of the regulatory role of the growth and proliferation of PGC in vitro cultures. (bvsalud.org)

After being inserted into the egg, the somatic cell nucleus is reprogrammed by its host egg cell. (wikipedia.org)

This includes liver disease, diabetes, age-related Macular Degeneration (AMD), corneal blindness and various neural degenerative diseases that are common among genetically different populations across the globe. (pharmaceutical-technology.com)

Donor fibroblasts were obtained from an ear-skin biopsy of a male Afghan hound and cultured for two to five passages (in which fully grown cells are transferred to a new culture dish). (nature.com)

As the embryonic cells divide and the daughter cells differentiate, they become increasingly specific. (thefutureofthings.com)
The separated cells also have the tendency to divide. (yourarticlelibrary.com)
Each of those two cells is able to divide indefinitely, "so from a small vial of those cells we could grow up as many cells as we would ever want," Lanza says. (usf.edu)

Modern biotechnology involves the use of genetically altered microorganisms (e.g. (biotechfront.com)
Developments in biotechnology have raised new concerns about animal welfare, as farm animals now have their genomes modified (genetically engineered) or copied (cloned) to propagate certain traits useful to agribusiness, such as meat yield or feed conversion. (wikiquote.org)

Several experimental strategies have been developed to derive iPSCs from differentiated somatic cells (summarized in Figure 1 ). (biomedcentral.com)

Adult stem cells can be used to accelerate bone or tendon healing , and they can induce cartilage progenitor cells to produce a better matrix and repair cartilage damage . (thefutureofthings.com)
The new International Stem Cell Corporation (ISCO) facility will produce human parthenogenic stem cells (hPSCs). (pharmaceutical-technology.com)
The facility will produce different cell types using the company's patented human parthenogenic stem cell (hpSC) technology, known as parthenogenesis. (pharmaceutical-technology.com)
Unfertilised human eggs are used to produce parthenogenic stem cells (hpSC) that have the ability to be immune-matched with millions of patients. (pharmaceutical-technology.com)
Perhaps this is worth celebrating for young women who cannot produce eggs on their own, as a first step toward novel fertility treatments. (eppc.org)

What are embryonic stem cells and what is their therapeutic potential? (myassignmentwriters.org)

if you have a choice of starting material and are forced to use embryonic stem cells to carry out the invention, ensure you describe the use of embryonic stem cells from morally acceptable sources in your patent application. (schlich.co.uk)

Anatomy49

Organisms32

Diseases8

Chemicals and Drugs43

Analytical, Diagnostic and Therapeutic Techniques and Equipment35

Psychiatry and Psychology1

Phenomena and Processes67

Disciplines and Occupations1

Technology, Industry, Agriculture5

Information Science4

Named Groups4

Health Care3

Identical34

Organism23

Embryo34

Blastocyst14

Embryos27

Pluripotent stem20

Sperm22

Established embryonic stem cell1

Oocyte7

Cloning32

ESCs1

Early embryonic development2

Oocytes5

Somatic cell donor1

Clone6

Genes9

Zygote7

Germ cells7

Totipotent1

Nuclear13

Reprogram1

Scientists19

Therapies6

Clones2

Gametes4

Tissues12

Researchers2

Mammalian1

Genetic material4

Development11

Humans3

Transplant1

SCNT9

Egg's2

Adult somatic1

Tissue9

Parkinson's2

Lines6

Fertilization5

Laboratory1

Hwang1

Create6

Biomedical research2

PGCs3

Nucleus is reprogrammed1

Populations1

Fibroblasts1

Divide3

Biotechnology2

IPSCs1

Produce5

Therapeutic potential1

Morally acceptable1