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The stem cell controversy is the consideration of the ethics of research involving the development and use of human embryos. (wikipedia.org)
Not all stem cell research involves human embryos. (wikipedia.org)
The discovery of adult stem cells led scientists to develop an interest in the role of embryonic stem cells, and in separate studies in 1981 Gail Martin and Martin Evans derived pluripotent stem cells from the embryos of mice for the first time. (wikipedia.org)
However, the use of the technique on human embryos led to more widespread controversy as criticism of the technique now began from the wider public who debated the moral ethics of questions concerning research involving human embryonic cells. (wikipedia.org)
Similar to embryonic stem cells (ESCs), hpSCs are pluripotent cells that can be reproduced into any type of cell within the human body without using or destroying the viable human embryos. (pharmaceutical-technology.com)
Embryonic stem cells (ESCs) are stem cells derived from human embryos. (patbirminghammd.com)
Depending on the source, stem cells can be classified into two broad categories i.e. embryonic stem cells that are derived from embryos and non-embryonic stem cells that are derived from adult and fetal tissues. (benthamscience.com)
Embryos used in embryonic stem cell research come from eggs that were fertilized in in vitro fertilization clinics, but were never implanted in the woman's uterus. (stem-cell-treatment.org)
Mature egg cells are produced by mitotic divisions, and these cells directly develop into embryos. (alchetron.com)
A type of undifferentiated stem cell found in embryos. (mayo.edu)
Such cells are derived from human embryos, and are undifferentiated, unlike other specialized cells in the human body. (nhsjs.com)
Proponents of stem cell research claim that the blastocyst is not human yet, and the embryos used for stem cell harvest are typically leftover from in vitro fertilization procedures with minimal chance that a human could ever develop from them. (nhsjs.com)
Adversaries of stem cell research argue that embryos are human and destroying one is equal to murdering a child. (nhsjs.com)
There are many types of stem cells, but most of the controversy surrounds embryonic stem cells, as they are derived from human embryos. (nhsjs.com)
The source of embryos is from those fertilized in vitro , and then donated for research with donor consent. (nhsjs.com)

Stem cell therapy is a form of regenerative medicine that utilizes the body's natural healing mechanism to treat various conditions. (patbirminghammd.com)
Stem cells are being used in regenerative medicine to renew and repair diseased or damaged tissues, and have shown promising results in treatments of various orthopedic, cardiovascular, neuromuscular and autoimmune conditions. (patbirminghammd.com)
The unique self-regeneration and differentiating ability of embryonic stem cells can be used in regenerative medicine. (patbirminghammd.com)
As a result, International Stem Cell will benefit from the development of either technology, but it is important that the public and the scientific community be fully aware of all alternatives in the field of regenerative medicine, not just the ones that capture public imagination at any particular time. (intlstemcell.com)
Stem cells are emerging as an important source of material for diseases in regenerative medicine. (benthamscience.com)
The study of biology of stem cells is the hallmark of the recent emerging field of regenerative medicine and medical biotechnology. (benthamscience.com)
Generating healthy cells to replace cells affected by disease (regenerative medicine). (stem-cell-treatment.org)
Research and clinical study on stem cell therapy are still in the early stages, but the combination of the potential benefits of an extremely safe procedure leads to a promising future for this natural regenerative technique. (stem-cell-treatment.org)
Twin Cities Pain and Regenerative Medicine is accepting new patients for stem cell treatment for knee, back and joint pain. (stem-cell-treatment.org)
There is no cure for osteoarthritis, but regenerative medicine therapies, such as platelet-rich plasma (PRP) and bone marrow-derived stem cell therapy, are a new generation of treatments that have been shown to be safe, effective and have long-lasting results. (stem-cell-treatment.org)
MSCs played a crucial role in regenerative therapy and have been introduced as an interdisciplinary field between cell biology and material science. (techscience.com)
From "adult stem cells" to "xenotransplantation," learn about common and specialized regenerative medicine terms. (mayo.edu)
A type of stem cell found in organs of the body that can be used for regenerative interventions. (mayo.edu)
Center for Regenerative Biotherapeutics protocols have been developed to generate adult stem cell-derived bonelike, nerve-like and heart-like tissues. (mayo.edu)
There are other, less controversial alternatives to embryonic stem cells, such as adult, fetal, cord blood, and induced pluripotent stem cells, but they have other biological restrictions that make them less promising for use in regenerative medicine at this time. (nhsjs.com)
Stem cell therapy aims to use special regenerative cells (stem cells) to repopulate areas of damage that result from spinal cord injuries, with the hope of improving the ability to move ("motor outcomes") and to feel ("sensory outcomes") beyond the site of the injury. (regenerativemedicine.net)

Embryonic stem cells (ESCs) can grow infinitely and give rise to all types of cells in human body, thus of tremendous therapeutic potentials for a variety of diseases, such as Parkinson's disease, spinal cord injury, and diabetes. (benthamscience.com)
Mouse nuclear transfer embryonic stem cells (NT-ESCs) were first established in 2000, and then proved to be able to differentiate either in vivo or in vitro, and give rise to individual tissues through germ line transmission or tetraploid complementation. (benthamscience.com)
Fully reprogrammed NT-ESCs are indistinguishable from ESCs derived from fertilized eggs functionally and substantially. (benthamscience.com)
What is more, by deriving NT-ESCs from patient cells, the problem of immune rejection may be avoided. (benthamscience.com)

cells that were extracted from fetal tissue, which was donated. (salon.com)
The chickenpox, rubella, hepatitis A, shingles and one rabies vaccine all derive from fetal embryo fibroblast cells cultivated in the 1960s -- and Catholic leadership has wrestled with the ethics of using those vaccines. (salon.com)
there are reasons to have conversations about embryonic stem cell research and fetal tissue research. (salon.com)

Yet further treatments using stem cells could potentially be developed due to their ability to repair extensive tissue damage. (wikipedia.org)
Adult stem cells are generally limited to differentiating into different cell types of their tissue of origin. (wikipedia.org)
Early polio research included the use of embryonic tissue . (salon.com)
Adult Stem Cells Taken from Human Fat Tissue Used to Treat Heart Failure Sweden Company Wants To Start First Stem Cell Research Factory Leading Scientist Charges Colleagues With "Misleading" Public British Stem Cell Researcher: Benefits of. (physiciansforlife.org)
As the embryo develops and forms a baby, stem cells are distributed throughout the body where they reside in specific pockets of each tissue, such as the bone marrow and blood. (patbirminghammd.com)
As we age, these cells function to renew old and worn out tissue and cells. (patbirminghammd.com)
These have been found to be an excellent source of stem cells or precursor cells that have the ability to multiply and transform into cells of any tissue. (patbirminghammd.com)
Stem cells are also being used in the treatment of various soft tissue (muscle, ligaments and tendons) as well as bone-related injuries. (patbirminghammd.com)
In addition to their ability to supply cells at the turnover rate of their respective tissues, they can be stimulated to repair injured tissue caused by liver damage, skin abrasions and blood loss. (thefutureofthings.com)
embryonic stem cells , resulting from the early divisions of the egg, characterized by their "pluripotency", i.e. the capacity, that they share with the egg cell itself, to produce all the cell types found in the adult organism, and the tissue-specific stem cells present in the tissues and organs of the adult. (pas.va)
These adult stem cells are highly specialized and can only produce the tissue in which they reside. (pas.va)
In addition, there has been remarkable progress in developing approaches to stimulate these tissue-resident stem cells in situ in the tissue. (pas.va)
Induced pluripotent stem cells, another types of pluripotent stem cells derived from any tissue by reprogramming and are the homologous source of stem cells. (benthamscience.com)
Both a rich source of adult stem cells, bone marrow and adipose tissue are acquired with a special collection system and then centrifuged at high speed to isolate stem cells. (stem-cell-treatment.org)
Then, the stem cells are carefully injected into the site where the damaged tissue exists and healing regeneration begins. (stem-cell-treatment.org)
Stem cell therapy also has other potential benefits, such as reducing inflammation, lessening or relieving pain, regenerating or repairing damaged tissue, and healing sports injuries. (stem-cell-treatment.org)
Stem cell injections are designed to heal and strengthen damaged tissue. (stem-cell-treatment.org)
The hope has been that this would eliminate the problem of the patient's immune system attacking the pluripotent cells as foreign tissue, which is a problem with most organs and tissues when they are transplanted from one patient to another. (pharmaceuticalintelligence.com)
This reaction could occur because cells created through SCNT contain mitochondria from the egg donor and not from the patient, and therefore could still look like foreign tissue to the recipient's immune system. (pharmaceuticalintelligence.com)
Undifferentiated cells, found in a differentiated tissue, that can renew themselves and - with certain limitations - differentiate to yield all the specialized cell types of the tissue from which they originated. (michaeljfox.org)
Enhanced expression of IL-6, IGF-1, TGF-β, and VEGF has also been observed in LC treated BMSCc+ groups, suggested the cardiac differentiation of BMSCc+, and can be utilized in tissue engineering for cardiac cell therapy. (techscience.com)
The Mesenchymal and Tissue Stem Cell Committee, which belongs to the International Society for Cellular Therapy, stated that plastic-adherent properties are the minimum criteria for determining MSCs. (techscience.com)
However, it can be challenging to differentiate when they are connected with wounded tissue, opposed to when they instruct tissue-specific progenitor cells responsible for the redevelopment of damaged tissue. (techscience.com)
The process of removing all the cells from a donor organ, such as a heart or lung, leaving behind just a tissue scaffold. (mayo.edu)
One explanation for deficient repair is when undifferentiated adult stem repair cells are inadequate in number or cannot be stimulated within the damaged tissue site. (journalofprolotherapy.com)
With improved understanding of tissue healing and regeneration, stem cell Prolotherapy is gaining significant clinical importance and potential. (journalofprolotherapy.com)
At first, the mesenchymal stem cell was thought to be the primary component of this undifferentiated cell type, however it is now evident that within the adipose extracellular matrix are also adipocytic precursors (known as progenitor cells) adherent to adipocytes, and in close approximation to a variety of additional undifferentiated multipotent and pluripotent cells, including pericytes and endothelial cells, all thought to play important roles in mesenchymal-stromal derived tissue regeneration. (journalofprolotherapy.com)
Extracellular vesicles (EVs) -- nanometer sized messengers that travel between cells to deliver cues and cargo -- are promising tools for the next generation of therapies for everything from autoimmune and neurodegenerative diseases to cancer and tissue injury. (regenerativemedicine.net)
The researchers induced injury by three hours of oxygen restrictions followed by 90 minutes of reoxygenation and then measured the fraction of dead cells and the contractile force of the tissue. (regenerativemedicine.net)
The heart tissue treated with EEVs had half as many dead cells and had a contractile force four times higher than the untreated tissue after injury. (regenerativemedicine.net)
Our findings indicate that EEVs could protect cardiac tissue from reoxygenation injury in part by supplementing the injured cells with proteins and signaling molecules that support different metabolic processes, paving the way for new therapeutic approaches," said Andr G. Kl ber, a Visiting Professor of Pathology at Harvard Medical School and co-author of the study. (regenerativemedicine.net)

Last week's newspapers carried the news of what was widely described as a significant "breakthrough" in stem cell science: the first successful human use of a technology known as Somatic Cell Nuclear Transfer (also referred to as SCNT). (intlstemcell.com)
I realize that I could be accused of bias because I am one of the founders of International Stem Cell, but, in fact, our company also owns license rights to some of the key intellectual property that is required to create cells through SCNT technology and our scientists are very familiar with its promise and its limitations. (intlstemcell.com)
Like embryonic stem cells and SCNT cells, these cells can be converted into almost any cell in the human body and thus have enormous potential for human therapy. (intlstemcell.com)
Unlike SCNT cells, parthenogenetic stem cells require no genetic manipulation or insertion of foreign DNA. (intlstemcell.com)
The cell lines that are produced from this method, unlike cell lines from embryonic stem cells or from SCNT, can potentially be matched to millions of people in the same way that an organ transplant is matched between donor and patient. (intlstemcell.com)
The promise of the SCNT method is that the nucleus of a patient's skin cell, for example, could be used to create pluripotent cells that might be able to repair a part of that patient's body. (pharmaceuticalintelligence.com)
One attraction of SCNT has always been that the genetic identity of the new pluripotent cell would be the same as the patient's, since the transplanted nucleus carries the patient's DNA. (pharmaceuticalintelligence.com)
Stanford University have raised the possibility in the past that the immune system of a patient who received SCNT-derived cells might still react against the cells' mitochondria, which act as the energy factories for the cell and have their own DNA. (pharmaceuticalintelligence.com)
When transplanted back into the nucleus donor strain, the cells were rejected although there were only two single nucleotide substitutions in the mitochondrial DNA of these SCNT-derived cells compared to that of the nucleus donor. (pharmaceuticalintelligence.com)
When scientists at the Oregon Health and Science University announced success in performing SCNT with human cells last year, it reignited interest in eventually using the technique for human therapies. (pharmaceuticalintelligence.com)
Although many stem cell researchers are focused on a different method of creating pluripotent stem cells, called induced pluripotent stem cells, there may be some applications for which SCNT-derived pluripotent cells are better suited. (pharmaceuticalintelligence.com)
The immunological reactions reported in the new paper will be a consideration if clinicians ever use SCNT-derived stem cells in human therapy, but such reactions should not prevent their use. (pharmaceuticalintelligence.com)
This research informs the medical community of the margin of safety that would be required if, in the distant future, researchers need to use SCNT to create pluripotent cells to treat someone. (pharmaceuticalintelligence.com)

This makes them potentially capable to help in effectively combatting a variety of degenerative diseases and conditions such as spinal cord injury, stroke or heart attacks. (nhsjs.com)

Many less controversial sources of acquiring stem cells include using cells from the umbilical cord, breast milk, and bone marrow, which are not pluripotent. (wikipedia.org)
To obtain stem cells from the bone marrow, a needle is inserted into the iliac crest of the pelvic bone to extract the stem cells. (patbirminghammd.com)
The procedure begins with your doctor extracting stem cells from your own bone marrow. (patbirminghammd.com)
Mesenchymal stem cells (MSCs) are multipotent cells usually isolated from bone marrow, endometrium, adipose tissues, skin, and dental pulp. (techscience.com)
A medical procedure in which healthy bone marrow stem cells are injected into the body to replace damaged or diseased bone marrow. (mayo.edu)
They are located either in the bone marrow, a copius beginning of root cells, or in peripheral system of the human organic structure.Embryonic root cells ( ES Cells )ES cells materializes from the procedure of fertilisation that occurs for about 5 yearss ( 3 ) Before human embryologic root cells came approximately, two scientists, Gail Martin and Martin Evans had discovered the mouse embryologic root cells. (lyceecharlesdegaulle.eu)

Researchers investigating many other conditions, including Parkinson's , also have been known to use embryonic stem cells. (salon.com)
In fact, by some estimates, as few as 100 parthenogenetic stem cell lines could provide immune-matched cells to over 50 percent of the world's population, and could accelerate disease therapies and treatments for severe chronic conditions, including diabetes, spinal cord injuries, liver diseases, blinding diseases such as macular degeneration, and neural diseases such as Parkinson's and Alzheimer's. (intlstemcell.com)
They can thus develop into brain, muscle, blood, skin, and other tissues and can, in theory, help with many health conditions involving organ dysfunction or failure, as well as cancer, injury, and may even address degenerative and otherwise incurable diseases such as Parkinson's and Alzheimer's disease. (nhsjs.com)
For example, experimental iPS cell therapies are being investigated that may one day replace neurons in Parkinson's Disease patient brains, different cell types of the eye for degenerative eye conditions , heart cells for heart disease , and more. (regenhealthsolutions.info)
Degenerative brain diseases include memory disorders such as Alzheimer's disease as well as Parkinson's disease and amyotrophic lateral sclerosis (ALS). (regenerativemedicine.net)

In 1998, James Thomson and Jeffrey Jones derived the first human embryonic stem cells, with even greater potential for drug discovery and therapeutic transplantation. (wikipedia.org)
The facility is also near leading Californian research institutions that have already collaborated with ISCO on basic stem cell biology and therapeutic applications. (pharmaceutical-technology.com)
ISCO will simultaneously partner with leading scientists across the world to showcase the therapeutic applicability and the potential advantages of hPSC over other stem cells. (pharmaceutical-technology.com)
A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)
Kuldip S. Sidhu , " Frontiers in Pluripotent Stem Cells Research and Therapeutic Potentials Bench-to-Bedside ", Bentham Science Publishers (2012). (benthamscience.com)
1, 2 Recently, Prolotherapists have begun to utilize the potential of autologous adipose (fat)-derived stem/stromal cells (AD-SC) within non-manipulated fat graft scaffolding, combined with high-density PRP concentrates (HD-PRP) to provide a potent biological therapeutic combination. (journalofprolotherapy.com)
With this study, we have mimicked a human disease on a chip with human cells and developed a novel therapeutic approach to treat it. (regenerativemedicine.net)
So, rather than one molecule that is therapeutic, we think that the exosomes contain a cocktail of molecules and proteins that can, all together, help the cell maintain homeostasis, deal with the stress, modify metabolic action and reduce the amount of injury. (regenerativemedicine.net)

Treatments that have been proposed include treatment for physical trauma, degenerative conditions, and genetic diseases (in combination with gene therapy). (wikipedia.org)
Gynogenesis and pseudogamy are closely related phenomena in which a sperm or pollen triggers the development of the egg cell into an embryo but makes no genetic contribution to the embryo. (alchetron.com)
A chemical compound or substance that inhibits oxidation - damage to cells' membranes, proteins or genetic material by free radicals (the same chemical reaction that causes iron to rust). (michaeljfox.org)
With that new understanding, researchers began working to answer key biological questions that surfaced from those early experiments: what genetic, biological, or chemical components were responsible for encouraging cells to go back to an earlier state and regain the potential to become any cell type? (regenhealthsolutions.info)
Outside of the body, patient-generated iPS cells retain the same genetic and/or cellular defects they do in the patient. (regenhealthsolutions.info)
These cells can be analyzed in labs to uncover the underlying mechanisms of the disease, including the identification of new genetic and environmental causes. (regenhealthsolutions.info)
When HIV infects a cell it first injects its genetic material RNA in this case into the cell along with the reverse transcriptase enzyme that transcribes the single-strand RNA molecule into a double-stranded DNA molecule. (regenerativemedicine.net)

There are plenty of legitimate reasons to question the unlikely philanthropic viral sensation of the summer -- from its gimmicky premise to the way it overshadows our own government's slashing of medical research funding -- but it's hard to argue with the more than $13 million raised for ALS so far, or the awareness the stunt has raised for the vicious and so far incurable degenerative disease. (salon.com)

The ability of our body to regenerate some of its tissues is largely owed to the reserves of adult stem cells. (thefutureofthings.com)
In the 1960s and 1970s, scientists discovered that there are cells within adult tissues of the body that harbor many of the same special properties as embryonic stem cells. (pas.va)
However, these adult stem cells have more restricted potential - they are specialized to replenish, rejuvenate, and repair the tissues in which they reside. (pas.va)
They are particularly active in tissues and organs in which the lifespan of the differentiated cells is short, like blood, skin and the inner cell layer covering the intestinal cavity, as well as in the repair of skeletal muscle after exercise of injury. (pas.va)
Significant advances have been made in isolating, culturing and reintroducing adult stem cells into tissues. (pas.va)
Stem cells can be guided into specific cells that can be used in people to regenerate and repair tissues that have been damaged or affected by disease. (stem-cell-treatment.org)
Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to an international study in mice by researchers at the Stanford University, MIT and colleagues in Germany and England. (pharmaceuticalintelligence.com)
Transplanting organs, tissues or cells from one person to another. (mayo.edu)
Transplanting tissues or cells from one area of a person's own body to another. (mayo.edu)
Using specific types of stem cells to repair damaged tissues and treat disease. (mayo.edu)
Recognition of the vast number of undifferentiated cells associated with the stromal vascular fraction has resulted in extensive research demonstrating the heterogeneity of such cells, and their ability to participate in production of all mesodermal-derived tissues. (journalofprolotherapy.com)
iPS cells could potentially be used to generate cell types that could be transplanted to replace those lost or damaged in organs or tissues due to injury or disease. (regenhealthsolutions.info)
Part of the innate immune system that is the body s first line defense against infection, dendritic cells sense the presence of pathogens in the blood or other tissues, ingest infecting organisms, and then display fragments of the invaders on their surface, which alerts and activates both killer and helper T cells (CD4 and CD8 cells), essentially teaching them to target the specific pathogen. (regenerativemedicine.net)

For many decades, stem cells have played an important role in medical research, beginning in 1868 when Ernst Haeckel first used the phrase to describe the fertilized egg which eventually gestates into an organism. (wikipedia.org)
At the top of the list comes the zygote-a fertilized egg, which of course has the ability to divide and differentiate into all cell types in the body and create a new organism. (thefutureofthings.com)
The first three divisions of the zygote give birth to eight totipotent cells, each of which also has the ability to become an entire organism. (thefutureofthings.com)
In the 1960s, the early days of stem cell research, John Gurdon was a student in the U.K. when he began working on cloning - transplanting the nucleus from the cell of one organism into the egg of another where the nucleus had been removed. (regenhealthsolutions.info)
In fact, in the right environment, adult cells could revert to an earlier, embryonic cell type that would be capable of giving rise to all the specialized cell types present in an adult organism. (regenhealthsolutions.info)

The ICM continues to differentiate into three germ layers-ectoderm, mesoderm and endoderm, each of which follows a specific developmental destiny that takes them along an ever-specifying path at which end the daughter cells will make up the different organs of the human body. (thefutureofthings.com)

In 1995 adult stem cell research with human use was patented (US PTO with effect from 1995). (wikipedia.org)
However, some evidence suggests that adult stem cell plasticity may exist, increasing the number of cell types a given adult stem cell can become. (wikipedia.org)
Many musculoskeletal conditions caused by sports injuries and overuse can be treated with all-natural adult stem cell procedures. (stem-cell-treatment.org)

One method of creating pluripotent stem cells is called somatic cell nuclear transfer, and involves taking the nucleus of an adult cell and injecting it into an egg cell from which the nucleus has been removed. (pharmaceuticalintelligence.com)
is a British developmental biologist who was the first to use nuclear transfer of differentiated adult cells to generate a mammalian clone, a Finn Dorset sheep named Dolly, born in 1996. (mathisfunforum.com)

Adult stem cells can be used to accelerate bone or tendon healing , and they can induce cartilage progenitor cells to produce a better matrix and repair cartilage damage . (thefutureofthings.com)

Egg harvesting and Embryonic Stem-cell Research Pose Serious Threat to Women's Health A congressional hearing last Thursday raised awareness on the risks to women's health and fertility by in vitro fertilization (IVF), human cloning, embryonic stem-cell. (physiciansforlife.org)
The technology known as "Parthenogenesis" begins with human eggs that are created and used every day throughout the world for in-vitro fertilization (IVF). (intlstemcell.com)
The controversy over embryonic stem cell research is caused by the fact that the procurement of these stem cells involves the destruction of the embryo produced during in vitro fertilization. (nhsjs.com)

It may be performed using cells from the patient's own body (autologous transplant) or cells from a donor (allogeneic transplant). (mayo.edu)

These are called adult stem cells or somatic stem cells. (patbirminghammd.com)

Because they are the patient's own cells, they escape immune rejection that remains a serious concern for current organ transplants from donors. (regenhealthsolutions.info)

The term stem cells dates back to the late 1800s at which time it referred to the fertilized egg, a pluripotent cell able to give rise to all of the complex cell types that comprise our body. (pas.va)

Stem cell therapies, once a dream, are now becoming a reality. (pas.va)
It's no secret that many athletes have taken advantage of stem cell therapies to extend their careers. (stem-cell-treatment.org)
Stem cell therapies hold vast potential for repairing organs and treating disease. (pharmaceuticalintelligence.com)
The petition recognizes that many "Canadians suffer from debilitating illnesses and diseases" and that the petitioners "support ethical stem cell research that has already shown encouraging potential to provide cures and therapies for these illnesses and diseases. (lifesitenews.com)
iPS cells have shown promise as a tool in predicting how particular patients will respond to potential therapies. (regenhealthsolutions.info)

Yamanaka was able to induce adult mouse cells to a pluripotent state whereby the cells mimicked embryonic stem cells and could become any cell type in the body. (regenhealthsolutions.info)
We are now focusing on fully understanding all the components required to trigger appropriate activation of dendritic cells in HIV infection, which may help to induce an elite-controller-like, drug-free remission of HIV in a broader patient population, explains Yu, an associate professor of Medicine at Harvard Medical School. (regenerativemedicine.net)

Umbilical Cord Blood Storage Company Sees Growth Umbilical Cord Stem Cell Storage Resources Arkansas House Votes to Create Umbilical Cord Stem Cell Bank Scientists Claim They Discovered Molecule That Might Help Embryonic Stem Cells Grow US Senate Vote for. (physiciansforlife.org)
While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
In the future, scientists might also lessen the immune reaction by using eggs from someone who is genetically similar to the recipient, such as a mother or sister. (pharmaceuticalintelligence.com)
Root Cells " , have ever grabbed the involvements of scientists in the biomedical field. (lyceecharlesdegaulle.eu)
Stem cells that have largely been dealt with by scientists can be classified into three chief signifiers ;Adult root cellsHarmonizing to Allman ( 2006 ) , this root cell was discovered by a former medical pupil at the Standford University named Irving Weissman in 1988. (lyceecharlesdegaulle.eu)
An important achievement in stem cell research was recognized in 2012, when the Nobel Prize in Physiology or Medicine was awarded to two scientists who transformed the field: Shinya Yamanaka and John Gurdon. (regenhealthsolutions.info)
The implications of the Gurdon/Yamanaka discovery have been wide-ranging and continue to help scientists understand cell biology and development. (regenhealthsolutions.info)
For sensory outcomes the degree of improvement tended to increase with the number of cells introduced -- scientists are often reassured by this sort of "dose response," as it suggests a real underlying biologically plausible effect. (regenerativemedicine.net)

The goal of stem cell therapy is to amplify the natural repair system of the patient's body by increasing the numbers of stem cells at injury sites. (patbirminghammd.com)

After HIV DNA enters the nucleus of an infected cell, it becomes integrated into the cellular DNA, turning it into an HIV factory that generates more virus particles. (regenerativemedicine.net)

In rodents, and even in some preliminary trials in humans, human embryonic stem cells have been shown to bridge gaps in spinal cord injuries , allowing restoration of motor functions. (thefutureofthings.com)
A particular field encouraged by the foundation is stem-cell research, with the great hope that it will result in the ability to get cells to differentiate into neurons and support cells to bridge the gap of a spinal cord injury. (thefutureofthings.com)
Will Stem Cell Therapy Help Cure Spinal Cord Injury? (regenerativemedicine.net)
A systematic survey of the scientific literature shows that stem cell therapy can have a statistically significant impact on animal models of spinal cord injury, and points the way for future studies. (regenerativemedicine.net)
High-profile campaigners like the late actor Christopher Reeve, himself a victim of sports-related spinal cord injury, have placed high hopes in stem cell transplantation. (regenerativemedicine.net)
In this case the authors assessed 156 published studies that examined the effects of stem cell treatment for experimental spinal injury in a total of about 6000 animals. (regenerativemedicine.net)
The authors went on to use their analysis to explore the effects of bias (whether the experimenters knew which animals were treated and which untreated), the way that the stem cells were cultured, the way that the spinal injury was generated, and the way that outcomes were measured. (regenerativemedicine.net)

Embryonic stem cells isolation primarily requires the consent of donors and can include the killing of fertilized eggs. (techscience.com)

Since pluripotent stem cells have the ability to differentiate into any type of cell, they are used in the development of medical treatments for a wide range of conditions. (wikipedia.org)
As the embryonic cells divide and the daughter cells differentiate, they become increasingly specific. (thefutureofthings.com)
These adult stem cells are considered multipotent, having the ability to differentiate into different cell types, albeit with a more limited repertoire than embryonic stem cells. (thefutureofthings.com)
When the stem cells divide, the new cell may remain a stem cell to divide again or may differentiate to become any of the 200 types of specialized cells in the human body. (nhsjs.com)

Situated in California, US, the new facility is located close to fertility clinics that provide donated human eggs to ISCO. (pharmaceutical-technology.com)
Unfertilised human eggs are used to produce parthenogenic stem cells (hpSC) that have the ability to be immune-matched with millions of patients. (pharmaceutical-technology.com)
Unlike embryonic stem cells, the human eggs used to create parthenogenetic stem cells are never fertilized and cannot become a human being. (intlstemcell.com)

This includes liver disease, diabetes, age-related Macular Degeneration (AMD), corneal blindness and various neural degenerative diseases that are common among genetically different populations across the globe. (pharmaceutical-technology.com)
The HLA genotypes of stem cells obtained from such oocytes are heterozygous and are genetically cloned to the donors. (pharmaceutical-technology.com)
The team used cells that were created by transferring the nuclei of adult mouse cells into enucleated eggs cells from genetically different mice. (pharmaceuticalintelligence.com)
The aim of the study was to create a genetically modified clone of mouse stem cells with a conditional knockout of humanized α-synuclein, which can be used for the reinjection into mouse blastocysts, as well as for basic and applied in vitro research in the field of pathophysiology and neuropharmacology. (eco-vector.com)
An approach to obtaining clones of mouse genetically modified stem cells expressing pathological humanized α-synuclein, has been proposed and implemented. (eco-vector.com)
The developed cell clone can serve to create a line of genetically modified mice that serve as a test system for pathophysiological and neuropharmacological studies associated with synucleinopathies. (eco-vector.com)

Great levels of success and potential have been realized from research using adult stem cells. (wikipedia.org)
Destruction of a human embryo is required in order to research new embryonic cell lines. (wikipedia.org)
Political leaders debate how to regulate and fund research studies that involve the techniques used to remove the embryo cells. (wikipedia.org)
But the story has taken a new twist as religious groups are now beginning to discourage followers from participating -- because ALS research at times relies on embryonic stem cells. (salon.com)
this research is funded by one specific donor, who is committed to this area of research. (salon.com)
She added that donors "can stipulate where their money goes and can ask that it not pay for embryonic stem cell research. (salon.com)
The Archdiocese suggests people who want to do the challenge contribute to the John Paul II Medical Research Institute, "where the research is only conducted using adult stem cells. (salon.com)
Stem cells are at the forefront of medical research and incite some of the most controversial ethical and religious debates worldwide. (thefutureofthings.com)
Recent advances in the field of stem-cell research are giving hope to millions. (thefutureofthings.com)
Protocols are approved by Independent Review Boards (IRBs) to protect the safety of donors and by an independent Stem Cell Research Oversight (SCRO) committee to insure compliance with state laws and research ethics, regulations established by the U.S. Food and Drug Administration (FDA) and the U.S. Department of Health and Human Services (HHS) Office for Human Research Protections, in addition to state-level requirements. (intlstemcell.com)
Stem cell research represents one of the most polarized biomedical controversies of our time. (nhsjs.com)
Considering the great potential of embryonic stem cell research, it is argued here that their research be allowed to be legal, federally funded, and its development a national priority. (nhsjs.com)
Stem cell research is one of the most controversial issues in modern medicine. (nhsjs.com)
In the United States currently embryonic stem cell research is allowed but there has been a lot of public controversy and legal setbacks. (nhsjs.com)
Two bills were proposed: The first one was the Stem Cell Research Advancement Act, which passed in both the House of Representatives and the Senate but was vetoed by President George W. Bush. (nhsjs.com)
This newer bill calls for prioritizing federally assisted advancement of embryonic stem cell research ( 1). (nhsjs.com)
Additionally, there have been two executive orders focusing on embryonic stem cells, one released by President George W. Bush prohibiting embryonic stem cell research and related federal funding, the other by President Barack Obama reversing the previous order but still with restrictions in place ( 2). (nhsjs.com)
This showcases the ambivalence of public perception, policy and legislation about stem cell research. (nhsjs.com)
Harmonizing to the National Institutes of Health resource for root cell research ( 2009 ) , a root cell is fundamentally an unspecialised cell that is able to self-renew and distinguish into many distinguishable types of mature cells. (lyceecharlesdegaulle.eu)
As such, this inimitable nature of these root cells is the principle of carry oning a research on it. (lyceecharlesdegaulle.eu)
As the guess sing root cells rises, there is much contention and statements between those who are in favor of the research and those who strongly oppose it. (lyceecharlesdegaulle.eu)
As a affair of fact, in this twenty-first century, apart from issues on animate being testing, root cell research excessively has become one of the most problematic topics. (lyceecharlesdegaulle.eu)
The argument on this country of treatment has led to this probe study which will consider on whether," Should Medical Research Involving The Use Of Human Stem Cells Be Permitted? (lyceecharlesdegaulle.eu)
Stem cells were foremost discovered by Dr. Ernest McCulloch, a medical research worker at the Ontario Cancer Institute in Toronto, Canada in 1960. (lyceecharlesdegaulle.eu)
Traveling on from this find, James Thomson from the University of Wisconsin and John Hopkins University had successfully discovered and segregated the human ES cells in order to be grown in the research lab. (lyceecharlesdegaulle.eu)
Collectively, the research by Gurdon and Yamanaka ushered in a new era that changed the face of stem cell research. (regenhealthsolutions.info)
In their paper published, the research team reports finding that dendritic cells of elite controllers are better able to detect the presence of HIV paradoxically through a greater susceptibility to HIV infection which enables them to stimulate the generation of T cells specifically targeting the virus. (regenerativemedicine.net)
While the connection between TBI and degenerative brain diseases has been known, no comprehensive research data exist on the impact of TBI on degenerative brain diseases among adults of working age. (regenerativemedicine.net)

Like embryonic stem cells, adult stem cells can also turn into more than one cell type, but their differentiation is restricted to a limited number of cell types. (patbirminghammd.com)
The term stem cell can be defined by two very important qualities: the cell has the ability to self-renew and, in a more general sense, the cell has not completed differentiation into its final state. (thefutureofthings.com)
This general definition includes a wide variety of cells with varying degrees of differentiation potential. (thefutureofthings.com)
Stem cells are not specialized and the process of their specialization is called differentiation. (benthamscience.com)
Mesenchymal stem cells (MSCs) are multipotent stromal cells capable of self-renewal and exhibit multilineage differentiation properties. (techscience.com)

Most commonly, this controversy focuses on embryonic stem cells. (wikipedia.org)

In stem cell transplants, stem cells replace cells damaged by chemotherapy or disease, or serve as a way for the donor's immune system to fight some types of cancer and blood-related diseases, such as leukemia, lymphoma, neuroblastoma, and multiple myeloma. (stem-cell-treatment.org)
Previously unseen immune reaction identified for stem cell transplants. (pharmaceuticalintelligence.com)

Currently, stem cell therapy is used to treat various degenerative conditions of the shoulder, knees, hips, and spine. (patbirminghammd.com)
For post-surgical recovery, stem cell therapy may be beneficial for people who have degenerative conditions, such as osteoarthritis. (stem-cell-treatment.org)

This avoids the key immune rejection issues associated with other stem cell classes. (pharmaceutical-technology.com)

Therefore we have chosen to use the term "adipose-derived stem/stromal cells" (AD-SC's), rather than simply "mesenchymal stem cells. (journalofprolotherapy.com)

The team also demonstrated that these intercellular travelers could be derived from endothelial cells, which line the surface of blood vessels and are more abundant and easier to maintain than stem cells. (regenerativemedicine.net)

Amnion and amniotic fluid may be obtained from a donor during gestation or at birth and developed into a biologic therapy agent in liquid form which may be cryopreserved for later use. (patbirminghammd.com)
A type of cell derived from amniotic fluid, which is the liquid that surrounds a developing fetus in the amniotic sac. (mayo.edu)

With high levels of platelet-derived growth factors and cytokines, this combination provides both a living bioscaffold and a multipotent cell replenishment source useful for enhanced musculoskeletal healing. (journalofprolotherapy.com)

Soon, Yamanaka and another scientist, James Thomson in the U.S., published studies showing that human cells could be similarly reprogrammed back to a pluripotent state. (regenhealthsolutions.info)

In early 2009, the FDA approved the first human clinical trials using embryonic stem cells. (wikipedia.org)
The non-embryonic stem cells like adult stem cells are in clinical use for many years and embryonic stem cells are now emerging as an alternative source for the same purpose with huge potentials in drug discovery and toxicological studies. (benthamscience.com)
The process of moving a scientific discovery into an actual treatment available for patients takes many years, even decades, and there is currently no medical treatment that directly involves iPS cells, though many are being developed and some are in clinical trial. (regenhealthsolutions.info)

Normal egg cells form after meiosis and are haploid, with half as many chromosomes as their mother's body cells. (alchetron.com)

The mesenchymal stem cell is the most commonly harvested. (patbirminghammd.com)

Because of this critical role of dendritic cells, the investigators explored the hypothesis that dendritic cells of elite controllers were better able to sense HIV and as a result to generate virus-specific T-cell responses. (regenerativemedicine.net)

These stem cells can be derived from eggs collected during IVF procedures with informed consent from the patient. (patbirminghammd.com)
It is possible, with informed consent from the IVF patient, to hold back some unfertilized eggs for creation of parthenogenetic stem cells, all at no additional risk to the donor. (intlstemcell.com)

This produces either heterozygous human parthenogenetic stem cell lines that can be precisely HLA-matched or stem cell lines histocompatible with the oocyte donors or HLA homozygous hPSC that are histocompatible with the major segments of human population. (pharmaceutical-technology.com)

Only cells from an embryo at the morula stage or earlier are truly totipotent, meaning that they are able to form all cell types including placental cells. (wikipedia.org)
Different cell types will be produced using hPSC technology. (pharmaceutical-technology.com)
The facility accommodates separate suites for developing and manufacturing different types of cells. (pharmaceutical-technology.com)
The facility will produce different cell types using the company's patented human parthenogenic stem cell (hpSC) technology, known as parthenogenesis. (pharmaceutical-technology.com)
There are two major types of stem cells: embryonic stem cells and adult stem cells. (patbirminghammd.com)
They are pluripotent, which means they have the ability to develop into almost any of the various cell types of the body. (patbirminghammd.com)
There are many types of stem cells, but the one with the most potential is the embryonic stem (ES) cell. (nhsjs.com)
Embryonic stem cells are totally undifferentiated and have the ability to divide and create multiple specialized cell types. (nhsjs.com)

7 There has been some variation and question regarding the correct terminology for this population of stromal adipose cells. (journalofprolotherapy.com)

Unlike induced pluripotent stem cells (iPSs), hPSCs do not manipulate the gene expression process back to a less differentiated stage, thereby avoiding the regulatory, ethical and safety obstacles. (pharmaceutical-technology.com)

The early mammalian embryo consists of the extra-embryonic cell layers-the trophoblast and a body of cells called the inner cell mass (ICM), which eventually become the embryo proper. (thefutureofthings.com)

The CRISPR/Cas9-mediated homologous recombination system with donor DNA oligonucleotides of the human sites of the corresponding gene sites was used to humanize the fourth and fifth exons. (eco-vector.com)
As a result of the study, a strategy for CRISPR/Cas9-assisted homologous recombination in the genome of mouse embryonic stem cells has been developed to create a fully humanized Snca gene encoding α-synuclein, and the clone genome of mouse embryonic stem cells has been edited using a CRISPR technology. (eco-vector.com)

These "diseases in a dish" can also be used screen thousands of chemical compounds to discover new drugs that could potentially treat disease-affected cells. (regenhealthsolutions.info)

Anatomy49

Organisms32

Diseases8

Chemicals and Drugs43

Analytical, Diagnostic and Therapeutic Techniques and Equipment35

Psychiatry and Psychology1

Phenomena and Processes67

Disciplines and Occupations1

Technology, Industry, Agriculture5

Information Science4

Named Groups4

Health Care3

Embryos15

Regenerative16

ESCs4

Fetal3

Tissue31

SCNT13

Diseases and conditions1

Bone marrow6

Parkinson's5

Therapeutic8

Genetic7

Incurable1

Tissues13

Organism5

Organs of the huma1

Adult stem3

Nuclear transfer2

Progenitor cells1

Vitro fertilization3

Allogeneic1

Somatic1

Organ1

Pluripotent cell1

Therapies5

Induce2

Scientists8

Patient's1

Nucleus1

Spinal7

Isolation1

Differentiate4

Human eggs3

Genetically6

Research28

Differentiation5

Controversy1

Transplants2

Conditions2

Immune rejection1

Stromal cells1

Endothelial cells1

Amniotic2

Multipotent1

James Thomson1

Clinical3

Haploid1

Mesenchymal1

Generate1

Informed consent2

Parthenogenetic1

Types8

Adipose1

Unlike1

Mammalian1

Homologous2

Potentially1