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Successful somatic-cell nuclear transfer (SCNT) depends on the quality, availability and maturation of the animal's unfertilized oocytes. (nature.com)
Figure 1: Dog cloned by somatic-cell nuclear transfer. (nature.com)
Stem cell treatments are a type of cell therapy that introduce new cells into adult bodies for possible treatment of cancer, somatic cell nuclear transfer, diabetes, and other medical conditions. (wikipedia.org)
The primary cloning technique is called "somatic cell nuclear transfer" (SCNT). (cbc-network.org)
It is the policy of Washington state that research involving the derivation and use of human embryonic stem cells, human embryonic germ cells, and human adult stem cells from any source, including somatic cell nuclear transplantation , is permitted upon full consideration of the ethical and medical implications of this research. (cbc-network.org)
Cloning, or somatic cell nuclear transfer (SCNT), is the technique used to produce Dolly the sheep, the first animal to be produced as a genetic copy of another adult. (eurostemcell.org)
One cloning technology that has been developed for mammalian and human cells is somatic cell nuclear transfer (SCNT). (news-medical.net)
It became a hot topic in 1996 when Dolly the sheep was cloned via a process called somatic cell nuclear transfer. (archstl.org)
They found that the spontaneous mutation frequency in ES cells is 100-fold lower than that in mouse embryonic fibroblasts (a somatic cell line), which is similar to adult cells in vivo . (i-sis.org.uk)
Photographs of (a) the procedure of somatic cell transfer (shown with the arrow) into the perivitelline space of an enucleated oocyte, (b) cloned bovine embryos used for transplantation to recipient animals, and (c) cloned calf (obtained in Russia for the first time). (isaaa.org)
The team led by Galina Singina at the Ernst Federal Science Center for Animal Husbandry managed to clone the calf using somatic cell nuclear transfer (SCNT), with embryonic fibroblasts as donors of nuclei. (isaaa.org)
Somatic-cell nuclear transfer, the technique by which Dolly was created, was first used 40 years ago in research with tadpoles and frogs. (who.int)
The nucleus of an adult somatic cell (such as a skin cell) is removed and transferred to an enucleated egg, which is then stimulated with electric current or chemicals to activate cell division. (who.int)
if it implants and the pregnancy goes to term, the resulting individual will carry the same nuclear genetic material as the donor of the adult somatic cell. (who.int)
Scientists were initially interested in somatic-cell nuclear transfer as a means of determining whether genes remain functional even after most of them have been switched off as the cells in a developing organism assume their specialized functions as blood cells, muscle cells, and so forth. (who.int)
Scientists from the Monash Institute of Medical Research (MIMR) and colleagues from New South Wales will compare two different methods of creating patient-specific stem cells: somatic cell nuclear transfer (SCNT) and induced pluripotent stem cells (iPS). (medicalxpress.com)
Direct neuronal reprogramming of a somatic cell into therapeutic neurons, without a transient pluripotent state, provides new promise for the large number of individuals afflicted by neurodegenerative diseases or brain injury. (lu.se)
This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)

Within a few years, unless the religious right manages to stop it, specialized cells developed from either embryonic or adult cells will be used therapeutically to treat everything from Parkinson's, Alzheimer's, diabetes, spinal injuries, heriditary impairments, and even the regeneration of diseased organs. (prospect.org)

Donor fibroblasts were obtained from an ear-skin biopsy of a male Afghan hound and cultured for two to five passages (in which fully grown cells are transferred to a new culture dish). (nature.com)
Other types of cell lines are also available in X. laevis including: fibroblasts lines of the different strains and LG clones, and a kidney cells line (A6). (rochester.edu)
Dermal fibroblasts were taken from a 35-year old male and a 75-year-old male and used to create embryonic stem cells. (news-medical.net)
The researchers used CRISPR-Cas9 technology to knock out PAEP and LOC100848610, two genes representing beta-lactoglobulin in the bovine genome, and obtain a line of gene-edited embryonic fibroblasts. (isaaa.org)
One isolate was passed 6 times in duck embryo fibroblasts, and the infected cells were then injected intramuscularly into 2 healthy Patagonian conures ( Cyanoliseus patagonis) . (cdc.gov)
Human CMV grows only in human cells and replicates best in human fibroblasts. (medscape.com)
2008). Historically, this concept is highlighted by the experi- factors are key intrinsic regulators of these fate decisions and mental phenomenon of lineage reprogramming, for example, that fate choice involves modulating networks of transcription by the conversion of fibroblasts to muscles cells following trans- factors. (lu.se)

To produce Dolly, the cloned blastocyst was transferred into the womb of a recipient ewe, where it developed and when born quickly became the world's most famous lamb. (eurostemcell.org)
This has led to a lot of interest in SCNT, which is best known as the method used to pioneer whole animal cloning technology, such as Dolly the sheep. (news-medical.net)
This led to the creation of Dolly the cloned sheep . (zmescience.com)
Researchers have been hoping to harness the therapeutic potential of cloning ever since the cloning of Dolly the sheep in 1997. (nih.gov)
When an embryo like this is implanted into a uterus, as with Dolly, the process is called reproductive cloning. (nih.gov)
When the world learned in 1997 of Dolly the sheep, the first clone produced from an adult mammal, a broad public discussion about the ethics of human cloning ensued, largely focused on the nature, meaning, and future of human procreation. (thenewatlantis.com)
Although many species produce clonal offspring in this fashion, Dolly, the lamb born in 1996 at a research institute in Scotland, was the first asexually produced mammalian clone. (who.int)
The difference with Dolly is that all her DNA originated in a cell from the udder of an adult sheep. (newscientist.com)
Dolly was the only lamb born from 277 fusions of oocytes with udder cells. (newscientist.com)
With the announcement last November that Ian Wilmut, who cloned Dolly the sheep, was ditching cloning in favor of the "amazingly efficient" method of induced pluripotent stem-cell research (iPS) - which reprograms adult stem cells into embryonic ones without using human embryos or eggs - pro-lifers had reason to celebrate. (crisismagazine.com)
One of the live-born lambs, Dolly, was derived from the transplantation of the nucleus of an adult mammary cell. (shawprize.org)
Thus, Dolly was the first example of the reprogramming of the adult cell back to totipotency in a mammal. (shawprize.org)

The researchers wanted to see whether "mature" cells that have differentiated to fulfil a specialised role (such as that of an udder cell or a fetal cell) could be returned to a primitive state from which they could grow into entire organisms. (newscientist.com)
Research advocates attack President Bush for "banning stem cell research," while pro-life advocates lament a Republican administration and Congress that have banned nothing-not embryo destruction, not human cloning, not fetal farming, not genetic engineering. (eppc.org)
Transplantations of fetal tissue in the 1980s and 1990s provided proof-of-concept for the potential of cell replacement therapy for PD and some patients benefitted greatly from their transplants. (lu.se)
The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)

The researchers say the finding, which has been successfully demonstrated in frog embryos, will help scientists control the differentiation of various cell types. (scitechdaily.com)
The learning resource provides an overview of stem cells, explains differentiation, embryonic, adult and induced pluripotent stem cells, theraputic stem cell cloning and stem cells as potential treatment for heart disease and nerve damage. (schoolscience.co.uk)
Derivation and differentiation of haploid human embryonic stem cells. (nature.com)
Genetic abnormalities associated with MDS block differentiation of hematopoietic stem and progenitor cells. (medscape.com)
First, we utilized single cell sequencing to dissect the differentiation of stem cells to midbrain dopaminergic neurons. (lu.se)
Aim: To detect the expression of molecules associated with Notch signaling pathway in stem cells from human exfoliated deciduous teeth (SHED) cultured in specific differentiation medium, namely, keratinocyte growth medium (KGM). (bvsalud.org)
Notch-1, Jagged-1, Jagged-2, and stem cell marker Nanog are expressed in SHED cultured in KGM which may be involved in the differentiation into epithelial-like cells in human dental pulp tissues. (bvsalud.org)
Since the Notch signaling pathway molecules play an important role in differentiation of epithelial cells, it is important to identify the presence of notch signaling molecules in SHED during the process of cell differentiation. (bvsalud.org)
The Notch signaling pathway provides important intercellular signaling mechanisms essential for cell fate specification and it regulates differentiation and proliferation of stem or progenitor cells by para-inducing effects 3-4 . (bvsalud.org)
Notch signaling pathway is also involved in the regulation of epithelial cell differentiation in various tissues 5-6 . (bvsalud.org)
Stem and progenitor cell populations are often heterogeneous, which may reflect stem cell subsets that express subtly different properties, including different propensities for lineage selection upon differentiation, yet remain able to interconvert. (lu.se)
A key challenge is to understand how state, but must also afford flexibility in cell-fate choice to permit the different cell-fate options confronting stem and progenitor cell-type diversification and differentiation in response to cells are selected and coordinated such that adoption of a given intrinsic cues or extrinsic signals. (lu.se)
Evidence the fate of stem cells has broad ramifications for biomedical suggests that during development or differentiation, cells make science from elucidating the causes of cancer to the use of very precise transitions between apparently stable ``network stem cells in regenerative medicine. (lu.se)
Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age. (lu.se)

The Threat of Human Cloning concludes by calling for laws prohibiting both human cloning and the creation of embryos for research. (thenewatlantis.com)
Some prohibit only cloning for reproductive purposes and allow the creation of cloned human embryos for research, whereas others prohibit the creation of cloned embryos for any purpose. (who.int)
At the same time, the statement calls for a five-year moratorium on the use of cloning to create human embryos for research purposes. (boloji.com)
Pro-cloning forces have been working hard to convince state governments to pass constitutional amendments enshrining a "right" to clone and to destroy embryos for research. (flfamily.org)

France prohibits reproductive cloning and embryo creation for research purposes, but enacted laws (with a sunset provision expiring in 2009) to allow scientists to conduct stem cell research on imported a large amount of embryos from in vitro fertilization treatments. (wikipedia.org)
Dramatic Uses for Adult Stem Cells - Bibliography Adult Stem Cells to be Tested in Repairing Human Heart Muscle For the first time, scientists will be able to see whether injections of bone marrow stem cells can actually help rebuild weakened human heart muscle. (physiciansforlife.org)
A protein that is necessary for the formation of the vertebrate brain has been identified by researchers at the Harvard Stem Cell Institute (HSCI) and Boston Children's Hospital, in collaboration with scientists from Oxford and Rio de Janeiro. (scitechdaily.com)
"PrimeGen , based in Irvine, California, says that its scientists have converted specialised adult human cells back to a seemingly embryonic state - using methods that are much less likely to trigger cancer than those deployed previously. (cbc-network.org)
The company also claims to be able to produce reprogrammed cells faster and much more efficiently than other scientists. (cbc-network.org)
However, following the successful derivation of human embryonic stem cells in 1998, the debate over human cloning largely shifted to the question of whether it is acceptable for scientists to create human embryos only to destroy them. (thenewatlantis.com)
But cloning research continued, and American scientists announced in 2013 that they had for the first time successfully obtained stem cells from cloned human embryos. (thenewatlantis.com)
1. Cloning is an umbrella term traditionally used by scientists to describe different processes for duplicating biological material. (who.int)
But scientists have not managed to isolate such cells from farm animals, and must rely instead on injecting genes randomly into early embryos. (newscientist.com)
Long before the controversy emerged over human embryonic stem cells, scientists and doctors began using first-generation stem cells from adult bone marrow. (eppc.org)
But they are also less equipped to produce every cell type of the body and less able to reproduce themselves indefinitely, which makes them less appealing to scientists interested in basic research. (eppc.org)
In July 2005, for example, scientists announced that they had engineered adult mouse stem cells into usable mouse eggs, a technique that might one day allow for the creation of human eggs from ordinary human cells. (eppc.org)
As the cell begins to divide, scientists believe stem cells can be extracted and grown into tissue or organs. (boloji.com)
The scientists honoured by the 2008 Shaw Prize in Life Science and Medicine used different approaches to reprogramme an adult cell into the totipotent or pluripotent state, and in doing so made important contributions to potential new approaches to improve agriculture practices and to treat human diseases. (shawprize.org)
Interest in using stem cells from cloned human embryos has revived after success by scientists in the United States and Korea. (bioedge.org)
Nature adds that rogue scientists might implant cloned embryos into wombs to create cloned children, a possibility which is widely condemned. (bioedge.org)
Scientists are unlikely to rush into creating human embryonic stem cell lines. (bioedge.org)
When mammalian cloning was first announced, Rush Limbaugh and others argued that scientists would never be able to create anything in a lab that has a soul. (acsh.org)
William Kristol now argues that therapeutic cloning, even if it works, will be so inefficient that it might as well be banned (though many scientists seem to disagree with him and a capitalist should know that inefficient practices tend to disappear without the need for bans anyway). (acsh.org)
Wesley J. Smith ("Cloning and Congress," July 1/July 8) expresses the oft-heard conservative confidence in adult stem cell research, while most scientists remain uncertain that adult stem cells will have the plasticity of embryonic stem cells. (acsh.org)
James Alexander Thomson, affectionately known as Jamie Thomson, is an American developmental biologist whose pioneering work in isolating and culturing non-human primate and human embryonic stem cells has made him one of the most prominent scientists in stem cell research. (asu.edu)
New techniques in cloning frozen mammals may allow scientists to bring back the mammoth. (singularityhub.com)
More than a decade after their first attempt, a team of Japanese scientists have announced that they will aim to clone a woolly mammoth in the next five years. (singularityhub.com)
As we recently discussed , scientists have been pursuing cloning endangered and extinct species with middling success. (singularityhub.com)
These scientists experimented eagerly in aims of learning how to clone human. (benjaminbarber.org)
Common answers to the puzzling questions about humans and cloning are still trying to be answered today, and scientists and the public are eager to learn all they can about cloning. (benjaminbarber.org)
Scientists have been all abuzz in the last few years over stem cells - cellular magicians that promise to dazzle and amaze. (cbc.ca)
Scientists say embryonic stem cells are the most useful type because they have the potential to become any type of cell within the body. (cbc.ca)
Scientists are fascinated by the ability of stem cells to become any type of cell. (cbc.ca)
The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)

Stem cells come in three forms: embryonic stem cells, embryonic germ cells and adult stem cells. (cbc.ca)
Embryonic stem cells come from embryos, embryonic germ cells from testes, and adult stem cells can come from bone marrow. (cbc.ca)
This paper outlines the debates prompted through a reproduction mechanism involv- by progress in cloning research, with special ing male and female germ cells. (who.int)

After many divisions in culture, this single cell forms a blastocyst (an early stage embryo with about 100 cells) with almost identical DNA to the original donor who provided the adult cell - a genetic clone. (eurostemcell.org)
These stem cells are genetically matched to the donor organism, holding promise for studying genetic disease. (eurostemcell.org)
Genetic match for the patient - you use their skin cells. (cbc-network.org)
This caused genetic changes that turned the adult cells into stem cells. (zmescience.com)
If cloning were to be done for reproduction, this would impose on the resulting individual a predetermined genetic identity, subjecting him - as has been stated - to a form of biological slavery, from which it would be difficult to free himself. (archdiocese-no.org)
Giving adults the opportunity to have what has been called the "ultimate 'single-parent child'" would contribute to the commodification of children, and would withhold from children the possibility of a relationship with both a genetic mother and father. (thenewatlantis.com)
This form of genetic engineering would deny the children it produces an open future, burdening them with the expectation that they will be like the individuals from whom they were cloned. (thenewatlantis.com)
And cloning could make possible still more dramatic forms of genetic engineering. (thenewatlantis.com)
Most natural cloning occurs in those species that produce their descendants asexually, that is, without combining the male and female genetic material. (who.int)
However, an animal created through this technique would not be a precise genetic copy of the source of its nuclear DNA because each clone derives a small amount of its DNA from the mitochondria of the egg (which lie outside the nucleus) rather than from the donor of cell nucleus. (who.int)
A clone is an organism that is a genetic copy of an existing one. (who.int)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
Next, the researchers take cells containing donor genetic material. (newscientist.com)
But what is not getting such wide reporting is the use of pluripotent stem cells (as well as many other types of cells and genetic engineering techniques) for reproductive purposes . (lifeissues.net)
The science fiction definition of "clone" suggests that the cloned organism would be an exact genetic copy of another creature-human or beast-created in the laboratory by any of a number of means. (all.org)
In therapeutic cloning on the other hand, genetic material from a body cell is inserted into an egg cell, replacing the nucleus. (boloji.com)
Wutz, A. Haploid mouse embryonic stem cells: rapid genetic screening and germline transmission. (nature.com)
Genetic modification and screening in rat using haploid embryonic stem cells. (nature.com)
Cloning embryos is different from the genetic process of in vitro fertilization, but still holds many similarities with it. (benjaminbarber.org)
A chemical compound or substance that inhibits oxidation - damage to cells' membranes, proteins or genetic material by free radicals (the same chemical reaction that causes iron to rust). (michaeljfox.org)

The information presented here covers the legal implications of embryonic stem cells (ES), rather than induced pluripotent stem cells (iPSCs). (wikipedia.org)
While embryonic stem cells are taken from embryoblasts, induced pluripotent stem cells are undifferentiated from somatic adult cells. (wikipedia.org)
Right now, the hottest area in stem cell biology is that of induced pluripotent stem cells, or iPS cells, which have the ability to develop into several different tissue types. (cbc-network.org)
His new method, known as induced pluripotent stem cells (IPS) , added chemicals to adult cells for about 50 days. (zmescience.com)
However, some features of these cells are said to be superior to induced pluripotent stem cells, their main rival at this point. (bioedge.org)
Using our recently established haploid human pluripotent stem cells (hPSCs), we generated a genome-wide loss-of-function library targeting 18,166 protein-coding genes to define the essential genes in hPSCs. (nature.com)
These progenitors which are derived from either embryonic stem cells (ESCs) or healthy induced pluripotent stem cells (iPSCs) express wild-type levels of a-syn, thus making them equally susceptible to developing Lewy bodies over time. (lu.se)

For SCNT, the chromosomes of the unfertilized canine oocytes were removed by micromanipulation, and a single donor cell was transferred into each enucleated oocyte. (nature.com)
If the authors of this bill really meant what they appear to have written, their legislation would ban all human cloning, since as we have seen, biologically, a new human organism, that is, a new human being, comes into existence with the completion of SCNT. (cbc-network.org)
This is junk biology since implanting isn't the act of asexual reproduction: SCNT cloning is. (cbc-network.org)
SCNT is a method of cloning mammalian cells that can be used to create personalized embryonic stem cells from an adult animal or human. (news-medical.net)
But SCNT can also be used to clone human cells for transplant or other therapies. (news-medical.net)
In humans, a major roadblock in achieving successful SCNT leading to embryonic stem cells has been the fact that human SCNT embryos fail to progress beyond the eight-cell stage. (news-medical.net)
This was the first successful reprogramming of human somatic cells into embryonic stem cells using a cloning technique, SCNT. (news-medical.net)
Another successful attempt at human SCNT was made using cells from two adult males. (news-medical.net)
SCNT, or therapeutic cloning, is one method used to produce a source of individually-tailored stem cells. (medicalxpress.com)
One aspect to this project will be to source oocytes, or immature egg cells to generate SCNT embryos from which embryonic stem cells are harvested. (medicalxpress.com)
Unlike SCNT, iPS cells are derived from adult cells, such as skin, which are reprogrammed to behave like embryonic stem cells. (medicalxpress.com)
Once our team produces the iPS cells, we will compare the properties of iPS versus cells developed through SCNT. (medicalxpress.com)
Australia is already a global leader in overall stem cell research and this new and clear regulatory framework gives us an opportunity to extend our leadership into SCNT which could transform how we treat diabetes, heart diseases and Parkinson's," Mr Jennings said. (medicalxpress.com)

That is what New Jersey legislators did when they passed and then Governor James McGreevey signed S-1909 last year, a law that was sold to the public as outlawing human cloning but which actually permits the creation of cloned human life, and its implantation and gestation up to and including the very moment prior to the emergence of the cloned baby from the birth canal. (cbc-network.org)

Along the same lines, a writer in the Baltimore Chronicle accused "opponents of embryonic stem-cell research" of "prolonging the suffering of millions. (breakpoint.org)
He labeled the president, and other opponents of embryonic stem-cell research, as an "obstacle to hope for a scientific breakthrough, a miracle. (breakpoint.org)
Pro-lifers fumed during the 2004 presidential race when John Kerry attacked opponents of embryonic stem-cell (ESC) research as "anti-science" ideologues who sought to block life-saving cures "right at our fingertips. (crisismagazine.com)

The nucleus of a body cell from the DNA donor is removed, and put into the place formerly occupied by the egg's nucleus. (cbc-network.org)
In this procedure, the nucleus of an egg cell is removed and replaced by the nucleus of a cell from another adult. (eurostemcell.org)
After being inserted into the egg, the adult cell nucleus is reprogrammed by the host cell. (eurostemcell.org)
The cloning method is based on the fact that cytoplasmic factors in mature, metaphase II oocytes are able to reset the identity of a transplanted adult cell nucleus to an embryonic state. (news-medical.net)
Cloning entails taking the nucleus - the compartment that contains the DNA - from an adult cell and putting it into an egg from which the original nucleus has been removed. (nih.gov)
The egg then "reprograms" the adult nucleus so that the cell behaves like an embryo but has the genes of the adult cell. (nih.gov)
Thus, the clone would be genetically identical to the nucleus donor only if the egg came from the same donor or from her maternal line. (who.int)
They pioneered a new technique of starving embryo cells before transferring their nucleus to fertilized egg cells. (shawprize.org)
When the nucleus of a stem cell has been the technique of cloning. (who.int)
The basic techniques of of the implanted nucleus, when it fully cloning have been known for some time, and develops. (who.int)

Wilmut and his colleagues fuse the empty oocyte with the donor cell by bringing them together and subjecting them to an electric current. (newscientist.com)
Generation of genetically modified mice by oocyte injection of androgenetic haploid embryonic stem cells. (nature.com)

One group from CHA University in Seoul reported in Cell Stem Cell in April that it had managed to use cell nuclei from two men, aged 35 and 75, to create embryonic stem cell lines. (bioedge.org)

Leeb, M. & Wutz, A. Derivation of haploid embryonic stem cells from mouse embryos. (nature.com)
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells. (nature.com)

General Assembly the following year,3 and the World Medical Association's Resolution on Cloning, endorsed in 1997, have confronted the issue but lack binding legal force. (who.int)
WHA50.37 of 1997 argues that human cloning is ethically unacceptable and contrary to human integrity and morality. (who.int)

There is nothing in the policy that stops researchers from using stem cells obtained elsewhere, like adult stem cells. (breakpoint.org)
In January 2007, researchers at Wake Forest University reported that "stem cells drawn from amniotic fluid donated by pregnant women hold much of the same promise as embryonic stem cells. (wikipedia.org)
According to modern stem cell researchers, Spain is one of the leaders in stem cell research and currently has one of the most progressive legislations worldwide with respect to human embryonic stem cell (hESC) research. (wikipedia.org)
The stem cells could be studied in the laboratory to help researchers understand what goes wrong in diseases like these. (eurostemcell.org)
Researchers from the Harvard Stem Cell Institute have identified a vital protein that can help determine embryonic development. (scitechdaily.com)
These findings could benefit stem cell researchers trying to create specific tissue types or organs in the lab. (scitechdaily.com)
In order to guide or direct stem cells to differentiate into a given cell type, such as neural cells or muscle cells, researchers continue to alter their experimental recipes, fine-tuning which molecules should be added to their dishes in what sequence and amount. (scitechdaily.com)
For those trying to create neural cells, "Notum is a necessary ingredient and new tool in the kit box for researchers to instruct human progenitor cells to become neural tissues," said He, who is also an American Cancer Society research professor. (scitechdaily.com)
Additionally, the researchers were able to demonstrate how Notum deactivates Wnt, which is a family of proteins that direct stem cells to "self-renew," or make more stem cells, among other things. (scitechdaily.com)
UK researchers have rejuvenated the skin cells of a 53-year-old woman so they are the equivalent of a 23-year-olds. (zmescience.com)
The technique used by Reik and his team comes from the 1990s when researchers from the Roslin Institute found a way to turn an adult mammary gland cell taken from a sheep into an embryo. (zmescience.com)
Researchers reported in Nature on November 22, 2007, that they successfully isolated 2 embryonic stem cell lines from cloned embryos made using cells from the skin of an adult rhesus macaque. (nih.gov)
Before this new study was published, Nature asked another group of researchers to confirm that the stem cells were genetically identical to the donor skin cells. (nih.gov)
The stem cells, the researchers showed, could turn into heart or nerve cells in the laboratory, and had other characteristics of established embryonic stem cell lines. (nih.gov)
In the first report [2], researchers from Edinburgh and Oxford took cells from the mouse brain marked with transgene 1, and cultured them together with ES cells marked with a second transgene, 2. (i-sis.org.uk)
These researchers pointed out that the spontaneous fusion rate (without interleukin-3) was extremely low, between 2-11 per million bone marrow cells, and is unlikely to account for all the findings with adult stem cells. (i-sis.org.uk)
In the current issue of the same journal [6], researchers compared the frequency and type of mutation induced in embryonic stem cells and embryonic somatic cells. (i-sis.org.uk)
Researchers from the Ernst Federal Science Center for Animal Husbandry, Skolkovo Institute of Science and Technology (Skoltech), Moscow State University, and their colleagues have produced the first viable cloned calf in Russia - and she recently turned one. (isaaa.org)
For each clone, the Roslin researchers combine material from two sources. (newscientist.com)
For the first time, US researchers have cloned embryonic stem cells from adult cells, a breakthrough on the path towards helping doctors treat a host of diseases. (medicalxpress.com)
However, the process is still ethically controversial, as researchers first create a human embryo and then destroy it to create stem cells. (bioedge.org)
Researchers there are working on technology that induces human skin cells to change into the kind of stem cells that have been created by embryos. (cbc.ca)
However, researchers at the Harvard Stem Cell Institute say reprogrammed cells won't eliminate the need or value of studying embryonic stem cells. (cbc.ca)

At that point - and this is important to understand - there is no more cloning to be done since a new human organism now exists. (cbc-network.org)
If the cloned human organism is to be experimented upon and destroyed, the process is often called "therapeutic cloning. (cbc-network.org)
Or to put it the other way around, cloning, not implantation, is what produces a new and distinct human organism. (cbc-network.org)
There are differences-so much so that despite the "exact copy" claim, the cloned organism is actually unique genetically. (all.org)
The fertilized egg is considered totipotent, as it can develop into a whole organism, while the cells in the embryo are pluripotent because they are capable of differentiating into somatic cells that make up all the organs. (shawprize.org)
XI - embryonic stem cells: embryonic cells that are capable of modifying the cells of any organism tissue. (hinxtongroup.org)
… "embryo" means a human organism during the first 56 days of its development following fertilization or creation, excluding any time during which its development has been suspended, and includes any cell derived from such an organism that is used for the purpose of creating a human being. (hinxtongroup.org)

And the federal policy doesn't prohibit the use of all embryonic stem cells. (breakpoint.org)
Whereas Germany, Austria, Italy, Finland, Portugal and the Netherlands prohibit or severely restrict the use of embryonic stem cells, Greece, Sweden, Spain and the United Kingdom have created the legal basis to support this research. (wikipedia.org)
Other policy options, such as supposed compromises that would prohibit "reproductive cloning" but permit "therapeutic cloning" by prohibiting not the act of creating a cloned embryo but the act of transferring a cloned embryo to a woman's uterus, would inherently mandate the wide-scale destruction of human embryos. (thenewatlantis.com)
General Assembly the adoption of a declaration on human cloning by which Member States were called upon to prohibit all forms of human cloning inasmuch as they are incompatible with human dignity and the protection of human life. (who.int)
Their 'Human Cloning Prohibition Act of 2002' would prohibit human reproductive cloning by imposing significant criminal and civil penalties in the form of fines (at least $1 million) and up to ten years in prison. (boloji.com)

It was believed that the epigenetic signature and age-related changes such as shortened telomeres and oxidative DNA damage might hinder reprogramming of mature adult nuclei. (news-medical.net)
The adult cell nuclei were transferred into metaphase-II stage human oocytes, producing a karyotypically normal diploid embryonic stem cell line from each of the adult male donor cells. (news-medical.net)
They performed nuclear transfer experiments in which nuclei from embryonic, foetal and adult cells of the sheep were transplanted into fertilized eggs derived from ewes. (shawprize.org)

Prior to September 11, the defining moment of the Bush presidency had been the president's decision to limit embryonic stem-cell research. (breakpoint.org)
Reeve, who was left paralyzed after being thrown from a horse a decade ago, was a tireless advocate of embryonic stem-cell research. (breakpoint.org)
Second, the policy applies only to research using federal money for embryonic stem-cell research. (breakpoint.org)
Federally funded research can be conducted using stem cell lines that were already available in August 2001. (breakpoint.org)
Stem cell laws are the law rules, and policy governance concerning the sources, research, and uses in treatment of stem cells in humans. (wikipedia.org)
The European Union has yet to issue consistent regulations with respect to stem cell research in member states. (wikipedia.org)
Germany has restrictive policies for stem cell research, but a 2008 law authorizes "the use of imported stem cell lines produced before May 1, 2007. (wikipedia.org)
In 2003, Spain's laws state that embryos left over from IVF and donated by the couple that created them can be used in research, including ES cell research, if they have been frozen for more than five years. (wikipedia.org)
The United Kingdom is one of the leaders in stem cell research, in the opinion of Lord Sainsbury, Science and Innovation Minister for the UK. (wikipedia.org)
A new £10 million stem cell research centre has been announced at the University of Cambridge. (wikipedia.org)
The bill purports to promote stem-cell research, while outlawing the cloning of a human being. (cbc-network.org)
While stem-cell research holds enormous potential for treating or even curing some diseases, the cloning of a human being is morally and ethically unacceptable…Any attempt to clone a human being is in direct conflict with the public policies of this state. (cbc-network.org)
What is cloning, and what does it have to do with stem cell research? (eurostemcell.org)
This form of cloning is unrelated to stem cell research. (eurostemcell.org)
Breast Milk Contains Stem Cells Adult Stem Cells Found to Cure Blindness - Three Patients Apparently Cured Destruction of Human Embryos for Stem Cell Research with Tax Dollars Poised to Begin: Comment Period / Comments Requested on Obama's New Human. (physiciansforlife.org)
at least half deal with non-embryonic stem cell research. (physiciansforlife.org)
Australian Physician/Bioethicist Reveals Huge Profits are Motive Behind Cloning and Embryonic Stem Cell Research Push Child with Cerebral Palsy Who Could Not See or Speak Does Both Following Umbilical Cord Stem Cell Therapy CA Conflict of Interest Successful Human. (physiciansforlife.org)
Remember, this is the research which takes and adult skin cell and then turns the stem cells back to an "embryonic" like state. (cbc-network.org)
Keep in mind, this is ethical adult stem cell research, which is in human clinical trials, helping patients NOW. (cbc-network.org)
Unlike *yawn* embryonic stem cell and cloning research which has produced zip to date. (cbc-network.org)
That's why Father Pacholczyk, director of education at the National Catholic Bioethics Center in Philadelphia, said that the efforts to help people understand the immorality of embryo reserch, including human cloning, must focus on humanizing the issue and appreciating our own embryonic origins, not just on the desired results of embryonic or other types of stem-cell research. (archstl.org)
A decade later, cloning came to the forefront in Missouri with the narrow passage of Amendment 2, a ballot initiative in 2006 that constitutionally protects embryonic stem-cell research and human cloning. (archstl.org)
The Catholic Church has always held that stem-cell research and therapies are morally acceptable, as long as they don't involve the creation and destruction of human embryos. (archstl.org)
The Church also supports research and therapies using adult stem cells, which are cells that come from any person who has been born - including umbilical cord blood, bone marrow, skin and other organs. (archstl.org)
A 9 page research paper that presents an overview of stem cell research that looks at possible benefits, but primarily focuses on the issues being debated and the biological realities involved, before arguing a stance regarding US guidelines on this topic, which favors loosening restrictions on this valuable line of research. (echeat.com)
Two separate research teams have figured out how to "reprogram" cells with just a handful of genes to give them the characteristics of embryonic stem cells. (nih.gov)
The petition recognizes that many "Canadians suffer from debilitating illnesses and diseases" and that the petitioners "support ethical stem cell research that has already shown encouraging potential to provide cures and therapies for these illnesses and diseases. (lifesitenews.com)
Britain s House of Lords final approval of therapeutic human cloning and embryonic stem cells research has intensified the battle for ascendancy between adult and embryonic stem cells. (i-sis.org.uk)
One example is the creation of the Institute of Cell Therapy, which is engaged in research into the adult stem cell and is against the use embryonic cells, this in the city that saw the rise and fall of phoney "cloning pioneer" Hwang Woo-suk. (asianews.it)
It was one of the trusty clichés of science journalists in the heated debates five or six years ago over embryo research, "therapeutic cloning" and embryonic stem cells. (crisismagazine.com)
Often aborted babies are harvested for Stem Cell Research. (archdiocese-no.org)
Although the latest scientific work related to cloning has been focused on potential medical applications, much of that research is relevant to the creation of cloned children. (thenewatlantis.com)
Cloning-for-biomedical-research is also profoundly unethical, as it turns human reproduction into a manufacturing process in the most literal sense: human embryos are created to serve as raw materials for the production of biomedical research supplies. (thenewatlantis.com)
Cloning-for-biomedical-research also endangers the health and safety of the women called on to undergo dangerous hormone treatments to serve as egg donors. (thenewatlantis.com)
If research cloning is not stopped now, we face the prospect of the mass farming of human embryos and fetuses, and the transformation of the noble enterprise of biomedical research into a grotesque system of exploitation and death. (thenewatlantis.com)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
Victoria and New South Wales have put aside their competitive interstate rivalry to collaborate on a stem cell research project, as announced by Innovation Minister Gavin Jennings and NSW Minister for Science and Medical Research, Verity Firth, today. (medicalxpress.com)
Mr Jennings said changes to the Victorian Infertility Treatment Act and the NSW Human Cloning and Other Prohibited Practices Act have opened up new opportunities for stem cell research in Australia. (medicalxpress.com)
These moral perils are surely not a reason to oppose adult stem cell research, which deserves vigorous and expanded public support. (eppc.org)
Before leaving office, President Clinton sought to get around the existing law without actually changing it, by funding research on embryonic stem cells so long as the actual embryo destruction was paid for with private dollars. (eppc.org)
The use of various types of stem cells for research purposes to make disease "models" in the lab for regenerative medicine and for "therapies" to cure sick patients for diseases is constantly in the news. (lifeissues.net)
increased public sensitivity and awareness together with the development of national regulations of governance of human cloning and embryo research in general. (lifeissues.net)
In particular, scientific developments in areas such as iPS cells open new possibilities of research and, at mid term, of therapeutic applications, but they also bring new ethical challenges and problems requiring further reflection and debate. (lifeissues.net)
3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
No harm comes to the person whose stem cells are obtained for research in such a fashion. (all.org)
There are those in the government and scientific community who say more money must be spent on human embryonic stem cell research because it holds the most promise for helping people with conditions such as Alzheimer's disease. (all.org)
Alzheimer's researcher Ned Potter said, however, that human embryonic stem cell research would not help the Alzheimer's patient at all. (all.org)
Contrary to the impression many people have, research involving human embryonic stem cells is not new. (all.org)
Yet, human embryonic stem cell research has thus far been unsuccessful in the quest to develop any therapeutic treatments. (all.org)
Therefore, it is speculated that those who support human embryonic stem cell research are clamoring loudly for taxpayer dollars because private companies know human embryonic stem cell research is neither worth their time nor their money. (all.org)
On the other hand, research involving adult stem cells has not only been around for a long time, it has also been used successfully for decades! (all.org)
It is further speculated that those who support human embryonic stem cell research are also seeking human embryos for the purposes of human cloning. (all.org)
While stem cell research and human cloning are complex topics, the facts are readily available. (all.org)
American feminists and women's health activists are debating on the difficult issue of human cloning and stem cell research. (boloji.com)
The bill also applies Federal ethical regulations on human subject research and outlaws the transfer of cloned embryos to a woman's uterus or to any artificial womb. (boloji.com)
However, the Senate bill does allow for therapeutic cloning, known as 'nuclear transplantation', for research on therapies that could cure several serious and life-threatening diseases. (boloji.com)
The Society for Women's Health Research, a non-profit group, agrees that therapeutic cloning should be allowed. (boloji.com)
While supporting research that would help to determine whether stem cells have therapeutic effects, they point out that those adult stem cells, umbilical cord stem cells, and embryonic stem cells not derived from embryos created for research can be used. (boloji.com)
And this week, the New York Stem Cell Foundation Research Institute announced in Nature that it had created a line of cells from a woman with Type 1 diabetes. (bioedge.org)
There have been many false dawns in the field of embryonic stem cell research, but these results seem to confirm that it is possible to use adult cells to create genetically matched stem cell lines. (bioedge.org)
So when I was recently contacted by an earnest and amiable member of a local school board who was concerned about the questionable manner in which the issue of "stem cell" research - both human embryonic and adult - was presented to the high school students in his district in a currently-used science textbook, I agreed to evaluate that section in the text for him. (lifeissues.net)
My edited analysis of the section on "stem cell research" in this science textbook is copied below. (lifeissues.net)
In my opinion there is no question but that the scientific information on stem cell research included in this science text book being used in Illinois schools incorporates some inaccurate scientific facts, and seems to be very partial to the use of human embryonic "stem cell" research. (lifeissues.net)
But then they tell us that adult stem cell research is morally acceptable even though the presence or absence of an egg cell membrane is the only discernible difference between the cells used in adult stem cell research and the cells used in embryonic stem cell research. (acsh.org)
Paul Wagle, M.A., discusses his experience with a life-saving adult stem cell treatment, and the importance of promoting ethical approaches to medical research. (flfamily.org)
CLI's Vice President and Research Director, Dr. David Prentice, recently joined Molly Smith, host of From the Median, to explain the science, history, and politics of stem cells. (flfamily.org)
In December 1999, the editors of Science, the journal devoted to scientific and medical matters, called stem cell research the 'Breakthrough of the Year. (cbc.ca)
Since then, there has been a flurry of announcements about developments in stem cell research and hints of promising treatments for diseases such as Alzheimer's, Parkinson's and cancer. (cbc.ca)
In May 2007, Ontario and California announced a $30-million stem cell research deal aimed at finding new therapies for those diseases. (cbc.ca)
Ontario and California together account for about 70 per cent of the stem cell research currently conducted in North America. (cbc.ca)
Some of that money would be aimed at turning the state into the second-largest stem cell research region in the United States. (cbc.ca)
This new method of generating stem cells does not require embryos as starting points and could be used to generate cells from many adult tissues, such as a patient's own skin cells,' said principal author Andras Nagy, senior investigator at Mount Sinai's Samuel Lunenfeld Research Institute. (cbc.ca)
On the issue of stem cell research, the gap between the scientific and religious cultures has never been wider. (prospect.org)
The potential of stem cell research to enhance human life is extraordinary. (prospect.org)
Should expensive therapies derived from stem cell research be covered universally by health insurance? (prospect.org)
He decreed that stem cell colonies produced before Aug. 9, 2001, could continue to receive federal funding for research purposes but no federal money could go to develop new stem cells from embryos. (prospect.org)
The life-enhancing promise of stem cell research is just too potent and the ethical questions too tricky to leave the issue in the hands either of private entrepreneurs or religious fundamentalists, much less both. (prospect.org)
Recent news of an impending clinical cell transplantation trial in Parkinson's disease using parthenogenetic stem cells as a source of donor tissue have raised hopes in the patient community and sparked discussion in the research community. (lu.se)
and (i i) to develop (epi)genomic powerful molecular and/or cell biology and close col aboration to create synergies methodologies, profiling strategies, and functional genomics tools, recent progress and better exploit and further expand bioinformatics tools and resources that in understanding of the cancer (epi) unique research tools and expertise. (who.int)

This was believed to be due to an inability to activate certain embryonic genes. (news-medical.net)
But, although the mutation frequency of genes was much lower in ES cells, mutant ES cells accumulated with time in culture. (i-sis.org.uk)
The fact that the DNA of a fully differentiated (adult) cell could be stimulated to revert to a condition comparable to that of a newly fertilized egg and to repeat the process of embryonic development demonstrates that all the genes in differentiated cells retain their functional capacity, although only a few are active. (who.int)
More importantly, biotechnologists will for the first time be able to manipulate the genes of cells from farm animals directly before growing them into embryos. (newscientist.com)
hPSC-enriched essential genes mainly encode transcription factors and proteins related to cell-cycle and DNA-repair, revealing that a quarter of the nuclear factors are essential for normal growth. (nature.com)
Fig. 2: Analysis of cell-essential genes. (nature.com)
But previous approaches required the use of viruses to deliver the four genes needed to activate the cell and accomplish that task. (cbc.ca)
explosion further, consider that a fictitious small genome with 2002) More recently and more dramatically, the potential for 260 genes would host the same number of combinations as cell state conversions is exemplified by the reprogramming of the number of atoms in the visible universe! (lu.se)

Elaboration of an international convention against reproductive cloning of human beings has been under consideration in the United Nations since December 2001 when the subject was included in the agenda of the fifty- sixth session as a supplementary agenda item at the request of France and Germany. (who.int)
2. Over the years, the international community has tried without success to build a consensus on an international convention against the reproductive cloning of human beings. (who.int)
3. Creating awareness among ministries of health in the African Region will provide them with critical and relevant information on the reproductive cloning of human beings and its implications to the health status of the general population. (who.int)
7. The WHO Regional Committee for Africa is invited to review this document for information and guidance concerning reproductive cloning of human beings. (who.int)
3. Media reports on nuclear transfer are usually about one form, reproductive nuclear transfer, also known as reproductive cloning of human beings . (who.int)

Cloning of a human being" means asexual reproduction by implanting or attempting to implant the product of nuclear transplantation [e.g., an embryo] into a uterus or substitute for a uterus with the purpose of producing a human being. (cbc-network.org)
Some in vivo transplantation studies have reported robust (35-50%) levels of transdifferentiation, which makes it unlikely that the results are due to cell fusion events. (i-sis.org.uk)
For pediatric patients with refractory cytopenia, certain cytogenetic abnormalities, or malignant transformation, hematopoietic stem cell transplantation (HSCT) from a matched related or unrelated donor early in the course of the disease is the treatment of choice. (medscape.com)
MDS is rare in childhood and may have a rapidly progressive course with an extremely poor prognosis without hematopoietic stem cell transplantation (HSCT). (medscape.com)
Based on discussions held by a global collaborative initiative on translation of stem cell therapy in Parkinson's disease, we have identified a set of key questions that we believe should be addressed ahead of every clinical stem cell-based transplantation trial in this disorder. (lu.se)

Embryonic stem cells were isolated in mice in 1981, and in humans in 1998. (wikipedia.org)
In most countries, it is illegal to attempt reproductive cloning in humans. (eurostemcell.org)
The protein, Notum, first discovered in fruit flies in 2002 and then found in mice and humans, is one of many that help determine embryonic development. (scitechdaily.com)
Help us to be faithful to this sacred trust so that we may protect and promote the dignity of every human life from the very moment of conception, particularly the tiniest humans in the embryonic stage of human development who are so often forgotten by society & used by modern science. (archdiocese-no.org)
If the same could be achieved in humans, it would mean that each of us could have clones of ourselves made from our own tissue. (newscientist.com)
But if, as seems likely, the Roslin team has succeeded in making an entire animal from adult tissue, it might be possible to do the same for humans. (newscientist.com)
During the development of vertebrates, including humans, the fertilized egg develops into the embryo, and the cells in the embryo then proceed to differentiate to form somatic cells of different tissues and organs. (shawprize.org)
We are far from understanding what trait is caused by each component of the human genome, but experiments in the replacement of diseased cells with newly cloned ones are well underway in animals and may soon help humans. (acsh.org)
Cloning humans has recently become a possibility that seems much more feasible in today's society than it was twenty years ago. (benjaminbarber.org)
It is not known when or how cloning humans really became a possibility, but it is known that there are two possible ways that we can clone humans. (benjaminbarber.org)
There is no doubt that many problems involving the technological and ethical sides of this issue will arise and will be virtually impossible to avoid, but the overall idea of cloning humans is one that we should accept as a possible reality for the future. (benjaminbarber.org)
Cloning humans is an idea that has always been thought of as something that could be found in science fiction novels, but never as a concept that society could actually experience. (benjaminbarber.org)

A common example of a stem cell is the hematopoietic stem cell (HSC) which are multipotent stem cells that give rise to cells of the blood lineage. (wikipedia.org)
In contrast to multipotent stem cells, embryonic stem cells are pluripotent and are thought to be able to give rise to all cells of the body. (wikipedia.org)
Stem cells from human exfoliated deciduous teeth (SHED) are multipotent stem cells derived from the pulp tissues of extracted deciduous teeth 1 . (bvsalud.org)

They produced idential lambs called Megan and Morag, which originated from different cells of the same embryo. (newscientist.com)
In 1995, they produced a pair of lambs called Megan and Morag from embryonic cells. (shawprize.org)

We tested whether the cloned dogs were genetically identical by microsatellite analysis of genomic DNA from the donor Afghan, the cloned dogs and the surrogates (see supplementary information ). (nature.com)
Analysis of eight canine-specific microsatellite loci confirmed that the cloned dogs were genetically identical to their donor dog. (nature.com)
Another long-term hope for therapeutic cloning is that it could be used to generate cells that are genetically identical to a patient. (eurostemcell.org)
By transferring adult cell DNA into an embryonic stem cell, it is possible to create a line of immortal embryonic cells that are able to develop into any type of adult cell, genetically identical to the donor. (news-medical.net)
In another strategy, called therapeutic cloning, the embryo can instead be used to create stem cells that are genetically identical to a patient. (nih.gov)
Beyond this scientific interest, the commercial concern in animal cloning focuses on replicating large numbers of genetically identical animals, especially those derived from a progenitor that has been modified genetically. (who.int)

When Notum was not present, the embryos would become a sack of skin cells with no head and a tiny brain, a result of embryonic progenitor cells making only epidermal but not neural cells. (scitechdaily.com)
The first part of the thesis (Paper I, II, III) shows the development and improvement of a hESC-based system of for virus-mediated direct reprogramming of human glial progenitor cells into both induced dopaminergic neurons (iDANs) and GABAergic interneurons. (lu.se)
To varying degrees, these fates also extend to the Such state stability is required in stem and progenitor cells to immediate progeny of stem cells, known as progenitor or support self-renewal and maintenance of the uncommitted transit-amplifying cells. (lu.se)

This kind of cloning is today being performed at several scientific labs in the United States, despite the availability of alternative techniques that produce cells of nearly the same scientific and medical value but that require neither the creation nor destruction of human embryos. (thenewatlantis.com)

For example, stem cells could be generated using the nuclear transfer process described above, with the donor adult cell coming from a patient with diabetes or Alzheimer's. (eurostemcell.org)
Those were spindle removal, donor cell fusion, and cytoplast activation. (news-medical.net)
The mitochondrial DNA of the stem cells, however, matched the donor egg's mitochondrial DNA. (news-medical.net)
The resulting cells were pluripotent and could be differentiated into insulin-producing beta cells to restore the function of the pancreas in the donor. (news-medical.net)
Wilmut says there were so many failures because it is difficult to ensure that the empty oocyst and the donor cell are at the same stage of the cell division cycle. (newscientist.com)

Kass calls it "cruel to suggest that stem-cell-based therapies are 'at our fingertips. (breakpoint.org)
These cells have been sought after as potential therapies for diseases ranging from heart disease to Parkinson's to cancer. (news-medical.net)
The holy grail of regenerative medicine-whatever one's ethical beliefs about destroying embryos-is to "reprogram" regular cells from one's own body so that individuals can be the source of their own rejection-proof therapies. (eppc.org)
Thus, a kind of 'regenerative medicine' gives people access to therapies derived from their own cells. (boloji.com)
The data presented in this thesis may serve as valuable resources to help optimize future cell replacement therapies for patients suffering from PD. (lu.se)
Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016? (lu.se)
Stem cell-based therapies for Parkinson's dis- ogy company International Stem Cell Corporation ease (PD) are rapidly moving towards clinical trials. (lu.se)

Cloning of human cells is a technology that holds the potential to cure many diseases and provide a source of exactly matched transplant tissues and organs. (news-medical.net)
They may instead be fusing with existing cells, creating genetically mixed-up tissues with unknown health effects" [1]. (i-sis.org.uk)
Today, we can derive stem cells from a range of adult and newborn tissues: liver cells, kidney cells, brain cells, fat cells, and umbilical cord blood. (eppc.org)
Stem cells exist naturally in the body to replace damaged cells and tissues. (schoolscience.co.uk)
But recent evidence suggests it may be possible to reprogram adult stems to repair tissues. (cbc.ca)

We discuss these properties with examples both from the hematopoietic and embryonic stem cell (ESC) systems. (lu.se)

He added that treatments for dreaded diseases "could be right at our fingertips" if we lifted "the stem cell ban. (breakpoint.org)
Father Tad Pacholczyk is convinced that embryonic stem cells will someday cure diseases. (archstl.org)
However, the use of stem cells to treat diseases is still extremely limited in the present day. (zmescience.com)
Since embryonic stem cells have the ability to form virtually any cell type in the body, those taken from a cloned embryo could potentially be used to treat many diseases. (nih.gov)
Already, non-embryonic stem cells are being used to treat a variety of diseases-most notably certain cancers of the blood. (eppc.org)
There are more than 70 diseases or conditions-including leukemia, immune system and other blood disorders, cancers, and autoimmune diseases-that respond well when adult stem cell therapy is used. (all.org)
The potential of therapeutic cloning for treating, and perhaps curing, a variety of debilitating diseases demands that the scientific community be allowed to continue this promising work. (boloji.com)
2. Omitting that the diseases everyone is talking about curing (diabetes, Parkinson's, paralysis) have already been treated with adult stem cells. (alexchediak.com)

Retrieved on December 04, 2023 from https://www.news-medical.net/life-sciences/Cloning-Human-Cells.aspx. (news-medical.net)

Attempts were then made to show that mammalian cells - and human cells in particular - could also be reprogrammed back to a pluripotent state, because it is believed that such knowledge may advance our understanding of developmental mechanisms, and yield new approaches for disease treatment. (shawprize.org)

The finding that adult cells can fuse with ES cells is therefore irrelevant to the debate, and the fact that it was used in an attempt to discredit adult stem cells is itself revealing, particularly in view of other recent findings on ES cells. (i-sis.org.uk)
Over the past few years, the debate over stem cells and cloning has grown both more complex and more profound. (eppc.org)
The heated debate in our society over reproductive cloning, as well as therapeutic cloning to obtain embryonic stem cells, has been fueled by misconceptions and hyperbole on both sides. (flfamily.org)
Regardless of how well read you are on the embryonic stem cell debate, I think you will find Brahm's treatment to be accessible and informative. (alexchediak.com)
The main issue as to whether or not human cloning is possible through the splitting of embryos began in 1993 when experimentation was done at George Washington University Medical Center in Washington D. C. There Dr. Jerry Hall experimented with the possibility of human cloning and began this moral and ethical debate. (benjaminbarber.org)
But there has been intense debate over the use of stem cells. (cbc.ca)
I recently participated in a debate at the Harvard Medical School on the ethics of stem cell cloning. (prospect.org)

WHA50.37, which states "the use of cloning for the replication of human individuals is ethically unacceptable and contrary to human integrity and morality. (who.int)
Obtaining stem cells from fatty tissue, bone marrow, or the umbilical cord after the birth of a baby, on the other hand, may be done ethically. (all.org)
The rapidly emerging "regenerative" field of medicine is relying heavily on the use of ethically obtained stem cells. (flfamily.org)

The second way to reproduce is a strictly human invention - known as "asexual" reproduction - or more commonly, cloning. (cbc-network.org)

Stem cells have been used to repair tissue damaged by disease. (wikipedia.org)
Two reports appeared as advance online publications in the top British journal Nature , accompanied by a news report that begins, "The hyped ability of adult stem cells to sprout replacement tissue types is being called into question. (i-sis.org.uk)
She is the first mammal ever created from the non-reproductive tissue of an adult animal. (newscientist.com)
Mammary glands are rich in these cells, which are more adaptable than other tissue. (newscientist.com)
In a study published in the online journal Nature on March 1, 2009, Canadian researches described a new method for generating stem cells from adult human tissue. (cbc.ca)
He explained that the early embryonic cells that his laboratory tries to turn into specialized tissue for therapeutic purposes hadn't even ''individuated'' yet. (prospect.org)
Undifferentiated cells, found in a differentiated tissue, that can renew themselves and - with certain limitations - differentiate to yield all the specialized cell types of the tissue from which they originated. (michaeljfox.org)
A control bird that received uninfected tissue culture cells remained healthy until it was euthanized at 77 days. (cdc.gov)
However, post-mortem analysis of transplanted tissue revealed accumulation of pathological Lewy bodies in a small subset of transplanted cells over time, revealing a host-to-graft disease propagation. (lu.se)
One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)

X. laevis is the only amphibian where true lymphoid tumors have been discovered and cell lines have been obtained opening new avenues for tumor biology and tumor immunity. (rochester.edu)
Dr Paul Verma, Program Leader of MIMR's Stem Cell Biology Program and the Chief Investigator of the Victorian project team, will create the iPS cells for this project. (medicalxpress.com)
Understanding cell-fate decisions in stem cell populations is a major goal of modern biology. (lu.se)

In Dolly's case, the cell came from the mammary gland of an adult ewe. (eurostemcell.org)

In therapeutic cloning, the blastocyst is not transferred to a womb. (eurostemcell.org)
Instead, embryonic stem cells are isolated from the cloned blastocyst. (eurostemcell.org)
After growing and dividing for a week or so in a laboratory culture dish, the fused cell forms an early embryo called a blastocyst, which Wilmut's team implants into a surrogate mother. (newscientist.com)

The breakthrough may eventually put to rest the ethical controversy surrounding stem cells. (nih.gov)
Human cloning is intrinsically illicit in that, by taking the ethical negativity of techniques of artificial fertilization to their extreme, it seeks to give rise to a new human being without a connection to the act of reciprocal self-giving between the spouses and, more radically, without any link to sexuality. (archdiocese-no.org)
From the ethical point of view, so-called therapeutic cloning is even more serious. (archdiocese-no.org)
The report offers an ethical and policy analysis, articulating what makes cloning morally repugnant and calling for the practice to be definitively prohibited in the United States. (thenewatlantis.com)
But adult stem cells also raise some interesting ethical dilemmas alongside their great therapeutic promise. (eppc.org)
Although we cannot clone a human yet, this experiment occurred almost two years ago and triggered almost an ethical emergency. (benjaminbarber.org)
At the same time, there are indeed myriad ethical questions raised by the effort to develop therapeutic applications of stem cell cloning. (prospect.org)
Among the real and knotty ethical questions are these: Should human embryos be created expressly to be used for stem cell extraction? (prospect.org)
Cloning technology, however, is perceived as having the potential for reproductive cloning, which raises serious ethical and moral concerns. (who.int)

In the second report [3], mouse bone marrow cells marked with green fluorescent protein were found to fuse with ES cells in culture in the presence of the cytokine, interleukin-3, which is known to encourage cell fusion. (i-sis.org.uk)
The cells could be made to differentiate into bone forming cells, cartilage forming cells, fat cells, skeletal muscle cells and endothelial cells. (i-sis.org.uk)
Two-color flow cytometric analysis of CD31 expression on BALC/c mouse bone marrow cells. (bdbiosciences.com)
Bone marrow cells were stained with APC Rat Anti-Mouse CD45R/B220 antibody (Cat. (bdbiosciences.com)
Two-color flow cytometric dot plots show the correlated expression patterns of CD31 (or Ig Isotype control staining) versus CD45R/B220 for gated events with the forward and side light-scatter characteristics of viable bone marrow cells. (bdbiosciences.com)
This event explains the presence of multiple derangements observed in the bone marrow that involve several cell lineages. (medscape.com)
As the affected cell lines continue to divide and to provide the marrow with dysplastic cells, bone marrow dysfunction becomes apparent. (medscape.com)
Myelodysplastic syndrome (MDS) in childhood encompasses a diverse group of bone marrow disorders that share a common clonal defect of stem cells and that result in ineffective hematopoiesis with dysplastic changes in the marrow. (medscape.com)

These investigators used ultra high-throughput sequencing combined with conventional PCR-based cloning to recover a complete viral genome sequence. (cdc.gov)

It is always and in every case morally wrong to intentionally kill an innocent human being at any point in life, including the embryonic stage of development. (all.org)

A year ago, we showed that you could do it with cells from embryos," says Wilmut. (newscientist.com)
They fuse as one cell," says Wilmut. (newscientist.com)
The technique synchronized the cell cycles of both cells and the results led Wilmut and Campbell to believe that any type of cell could be used to produce a clone. (shawprize.org)
Since then, the work of Wilmut and Campbell has been duplicated in many other animal species and has provided approaches to produce useful therapeutic products with cloned animals and to improve agricultural practices. (shawprize.org)

The therapeutic potential of cloned human cells has been demonstrated by another study using human oocytes to reprogram adult cells of a type 1 diabetic. (news-medical.net)

Here we describe the cloning of two Afghan hounds by nuclear transfer from adult skin cells into oocytes that had matured in vivo . (nature.com)

In addition, the possibility of reprogramming adult stem cells back to a "pluripotent" (or embryonic-like) state raises the biological prospect of going back too far. (eppc.org)

If the insertion is successful, the eggs will be placed in an adult elephant and brought to term. (singularityhub.com)
Should women be paid to donate eggs or fertilized embryos to stem cell labs? (prospect.org)

The hybrid cells carrying four sets of chromosomes (instead of the usual two) behaved as stem cells when injected into mouse embryos. (i-sis.org.uk)

In Alzheimer's, it is the degeneration of the nerve cells that cause the problem because they lose their ability to connect with each other. (all.org)

To date, no human embryonic stem cell lines have been derived using therapeutic cloning, so both these possibilities remain very much in the future. (eurostemcell.org)
They derived several human embryonic stem cell lines from these cloned embryos whose DNA was an exact match to the adult cell that donated the DNA. (news-medical.net)
Professor Tuch's team will also use their proficiencies in characterising human embryonic stem cell lines and bioinformatics. (medicalxpress.com)

Anatomy54

Organisms28

Diseases6

Chemicals and Drugs71

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Disciplines and Occupations1

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Named Groups1

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19972

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20231

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