Embryo research. Medical search. Frequent questions

Yet, frozen embryo transfer is known to be associated with a higher risk of hypertensive disorders in pregnancy than both natural conception and fresh embryo transfer. (miragenews.com)
Frozen embryo transfers are now increasingly common all over the world, and in the last few years, some doctors have begun skipping fresh embryo transfer to routinely freeze all embryos in their clinical practice, the so-called 'freeze-all' approach," said Sindre H. Petersen, M.D., the study's lead author and a Ph.D. fellow at the Norwegian University of Science and Technology in Trondheim, Norway. (miragenews.com)
This analysis found that the risk of high blood pressure in pregnancy was substantially higher after frozen embryo transfer compared to pregnancies from fresh embryo transfer or natural conception. (miragenews.com)
Pregnancies from fresh embryo transfer did not have a higher risk of developing hypertensive disorders compared to natural conception, neither in population level analysis nor in sibling comparisons. (miragenews.com)
Among other findings, women in the study who gave birth after IVF pregnancies were average age 34 years for frozen embryo transfer, 33 years for fresh embryo transfer and 29 years for those who conceived naturally. (miragenews.com)
This study supports that it is safe to transfer poor quality embryos when they are the only option for fresh embryo transfer (ET). (biomedcentral.com)
Birth outcomes are compared after elective cryopreservation and delayed transfer versus fresh embryo transfer. (medscape.com)

Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure. (centerwatch.com)
Endometrial induced injury has been suggested that could improve embryo implantation in cases of patients with recurrent implantation failure. (centerwatch.com)
And they report that implantation and pregnancy rates were similar regardless of embryo type and culture. (institutobernabeu.com)
But their data are not sufficient to overturn our current understanding that embryo implantation is independent, and we do not have evidence that individual embryos 'help each other' implant. (mommyish.com)
Mitalipov's group never intended to implant the eggs into a womb, but the embryos were "clinical quality" and probably could have survived implantation. (wired.com)
Physiological and molecular determinants of embryo implantation. (bilpublishing.com)
Regulatory T cells in embryo implantation and the immune response to pregnancy. (bilpublishing.com)
No significant differences in the implantation rate, clinical pregnancy rate, miscarriage rate, live births, and the number of children born were found between the groups of poor quality embryos transferred on day 3 and day 5. (biomedcentral.com)
Though the implantation rate was lower for the group of poor quality embryos, than for the control (13.9% vs 37.2%), statistically significant differences between the proportion of implanted embryos which resulted in clinical pregnancies and live births in both groups were not observed (72% vs 78.2 and 55.8% vs 62.0% respectively). (biomedcentral.com)
Transfer of poor quality embryos at either day 3 or day 5 have a low potential for implantation, though those embryos which successfully implanted have the same potential for live birth as the embryos of fair and good quality. (biomedcentral.com)
This decision relies on the fact that the implantation potential of poor quality embryos is much lower than of good or fair quality. (biomedcentral.com)
We carried out a prospective randomized trial on 220 couples with nontubal factor infertility to compare pregnancy rates and implantation rates after zygote intrafallopian transfer (ZIFT) and uterine embryo transfer (UET). (who.int)
Microinjection of DNA or ES cells into pre-implantation stage embryos. (irbbarcelona.org)
Abstract BackgroundTo determine whether Gonadotropin-releasing hormone (GnRH) agonist down regulation combined with hormone replacement treatment (HRT) can improve the reproductive outcomes in the frozen thawed embryo transfer (FET) cycle of elderly patients with idiopathic recurrent implantation failure (RIF). (sciencegate.app)
The major areas of research that might have application in the development of regenerative endodontic techniques are (a) postnatal stem cells, (b) scaffold materials, (c) morphogen/growth factors, (d) implantation. (bvsalud.org)

One IVF treatment process available utilizes frozen embryos: after an egg is fertilized by sperm in the lab, it is frozen using a cryopreservation process before being thawed and transferred to the uterus at a later date. (miragenews.com)
The procedure is becoming more common because of the significantly improved freezing technology or cryopreservation methods that started in the late 2000s and because more patients are choosing to freeze embryos, according to the study authors. (miragenews.com)
In general, embryos of poor morphology are not favored to be selected for the embryo transfer, nor for the cryopreservation, and thus are often discarded. (biomedcentral.com)
Improvement in cryopreservation procedures has permitted conservation of supernumerary embryos for use in future cycles, and refinements in culture frameworks and embryo selection have brought about the transfer of elective single embryos while keeping up positive pregnancy rates. (scirp.org)
Controlled ovarian stimulation (COS) followed by embryo and/or oocyte cryopreservation is the FP method recommended by both the ASCO and ISFP. (medscape.com)
Embryo cryopreservation is a well-established technique and has been used in fertility centers worldwide for the past 30 years in noncancer patients. (medscape.com)

2016, Developmental Cell ), we demonstrated the generality of RACE by extracting cell-shape information from entire Drosophila , zebrafish, and mouse embryos imaged with confocal and light-sheet microscopes. (janelia.org)
β-gal expression was assayed in tissue sections of transgenic mouse embryos at different stages of development. (nih.gov)
Figure 1: Electroporation-mediated gene expression in cultured chick and mouse embryos. (nature.com)

In-Vitro Fertilization and Embryo Transplantation is a medical technique which is available for the treatment of infertility in many parts of the world. (wma.net)
The technique of in vitro fertilization and embryo transplantation can also be useful in research directed towards a better understanding of how genetic defects arise and are transmitted, and how they might be prevented or treated. (wma.net)
The principles of the World Medical Association's Declaration of Helsinki will apply to all clinical research in respect to in-vitro fertilization and embryo transplantation, as well as all problems that arise out of such clinical research. (wma.net)
The technique of in-vitro fertilization and embryo transplantation creates the possibility of donation of ova, sperm, and embryo, so that the biological donors may not be the parents of the child produced by this procedure. (wma.net)
Such use of donated gametes or embryo may present serious legal, moral, and ethical issues for both patients and physicians involved in such in-vitro fertilization and embryo transplantation procedures. (wma.net)
In conducting the research, Song collected fruit fly eggs at different times after fertilization in the lab. (innovitaresearch.com)
We present preliminary results using the prototype, which enables the acquisition of electrophysiological signals from in vivo 3 and 5 days-post-fertilization zebrafish embryos. (sussex.ac.uk)
To investigate the impact of antithyroid antibody on pregnancy outcome following the in vitro fertilization and embryo transfer (IVF-ET). (medsci.org)
To date, no consensus has been achieved on the impact of ATA on the outcome of in vitro fertilization and embryo transfer (IVF-ET). (medsci.org)
DALLAS, Sept. 26, 2022 - In vitro fertilization (IVF) using frozen embryos may be associated with a 74% higher risk of hypertensive disorders in pregnancy , according to new research published today in Hypertension, an American Heart Association journal. (miragenews.com)
In comparison, the study found that pregnancies from fresh embryo transfers - transferring the fertilized egg immediately after in vitro fertilization (IVF) instead of a frozen, fertilized egg - and pregnancy from natural conception shared a similar risk of developing a hypertensive disorder. (miragenews.com)
All patients undergoing embryo transfers of poor quality embryos on day 3 or on day 5 as part of fresh In Vitro Fertilization (IVF) cycles performed between 2012 and 2016. (biomedcentral.com)
A total of 52 couples with normal karyotypes underwent in vitro fertilization, and 162 embryos were donated for genetic screening. (eurekamag.com)
Embryos in IVF group were generated by mature follicles retrieved during gonadotrophin-stimulated in vitro fertilization (IVF) cycles. (eurekamag.com)
However, the authors pointedly avoid mention of CRISPR, and while their survey covers speculative technology like gene editing and human cloning, it also looks at established practices like tests for genetic disease in embryos during in vitro fertilization (IVF). (bio-itworld.com)
Zebrafish embryos were treated with extractable organic matters (EOM) from PM2.5 at 5 µg/mL in the presence or absence of antioxidant N-acetyl-L-cysteine (NAC, 0.25 µM) at 2 h post fertilization (hpf). (bvsalud.org)

An Instituto Bernabeu study has compared the individual and group embryo culture to determine the rate of blastocyst formation and their quality. (institutobernabeu.com)
The researchers observed that single culture improves the rate of blastocyst formation and usable embryos. (institutobernabeu.com)
Impact of group embryo culture vs individual embryo culture strategies on blastocyst rate and quality. (institutobernabeu.com)
At the blastocyst stage, there is a higher probability of euploidy among good morphology blastocysts, yet still, the effect of aneuploidy on the embryo quality is rather subtle [ 1 ]. (biomedcentral.com)
Nowadays, the majority of transfers are performed either on day 3 at the cleavage stage, or on day 5 at the blastocyst stage, and it is advised not to transfer more than 2 embryos at once to minimize the risk of complications in both the mothers and the fetuses [ 10 , 11 ]. (biomedcentral.com)
The willful exchange of a single top notch quality elective single embryo transfer e-SET (Blastocyst) has fundamentally lessened the multiple gestation rates and boosted the rate of singleton pregnancy without compromising the global success rates. (scirp.org)
Elective single-embryo transfer (e-SET) is a procedure in which one top quality embryo is selected from a larger number of existing embryos (cleavage stage or blastocyst), and is placed in the uterus. (scirp.org)
MethodsThis is a retrospective cohort study analyzing 594 elderly patients (aged 36~43 years old) undergoing third cleavage embryo or blastocyst transfer over nearly 5-year period (January 2015-November 2020) at Northwest Women's and Children's Hospital after IVF-ICSI cycles. (sciencegate.app)
Embryonic stem cells are stem cells derived from the inner cell mass of an early, preimplantation stage embryo known as a blastocyst. (bvsalud.org)

The three-day meeting drew scientists, ethicists, patient advocates, regulators, and others from around the world to wrestle with profound questions: Is it ethical to rewrite the genetic code of the human race in sperm, eggs, or early embryos - the human "germline" - so that the repairs are passed down to any future children? (statnews.com)
New Scientist ) - A team in China has corrected genetic mutations in at least some of the cells in three normal human embryos using the CRISPR genome editing technique. (georgetown.edu)
The team allowed the embryos to develop for a few days, and according to the original and subsequent reports a battery of tests revealed that the resulting embryos took up the desired genetic changes in the majority of their cells with few errors. (wired.com)
Scientists are only supposed to edit embryos to prevent a baby from inheriting a serious genetic disease, and only if the doctors meet specific safety and ethical criteria, and if the parents have no other options. (wired.com)
Changes in genetic expression affect the development of fly embryos as shown, with an unaltered embryo at top and mutant version below. (innovitaresearch.com)
In just two hours, a fly embryo grows from a single, fertilized egg cell into more than 6,000 individual cells - each with a set of DNA-encoded, genetic instructions. (innovitaresearch.com)
An analysis showed that hour-old embryos did not contain enough DNA building blocks to continue meeting the genetic demands of the many thousands of new cells that had yet to form. (innovitaresearch.com)
However, with the development of preimplantation genetic screening, we came to the realization that the current morphological analysis cannot be relied on for choosing an euploid embryo. (biomedcentral.com)
To evaluate the benefit of next-generation sequencing (NGS)-based preimplantation genetic testing for aneuploidy (PGT-A) for embryo selection in frozen-thawed embryo transfer. (nih.gov)
The 14-day rule, which is the law in nations that lead genetic research, including the United States and Britain, was established in 1985 after the birth of the first "test tube baby," Louise Brown. (wnd.com)
Research suggests that most cases of MZ twinning are not caused by genetic factors. (medlineplus.gov)
But many scientists think it may be ethical someday to use the powerful new gene-editing technique known as CRISPR to edit the DNA in human embryos to prevent genetic disorders. (wuwm.com)
5. Most countries in the African Region have no specific regulations and policies governing genetic manipulations for assisted conception, treatment and research. (who.int)
2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
Study of Genetic Fidelity of Somatic Embryos - Derived Plants of Gentiana kurroo Royle from Western Himalayas - Plant of Great Medicinal Value. (who.int)

The Clinton administration will release guidelines later today that will enable federally funded scientists to conduct research using stem cells, harvested from human embryos, despite the persistent opposition of anti-abortion activists. (feminist.org)
A review committee of scientists and ethicists will be formed to monitor the research. (feminist.org)
While the deferral will hold up stem cell research by the teams from King's College London and Newcastle University that have applied to use hybrid embryos created by implanting human DNA into animal eggs, it will also allow some breathing space for scientists who support the practice to take their arguments to politicians and the UK public. (pharmatimes.com)
Scientists and the biotechnology industry have warned that the UK could lose its lead in the field if the proposed ban on hybrid embryos is not overturned. (pharmatimes.com)
Californian scientists recently grew the first human-pig embryos , and Japanese scientists say they've grown a replacement pancreas for a mouse inside a rat. (edu.au)
Yet, primarily due to moral considerations, stem-cell scientists have to work within many limitations placed on their research. (edu.au)
On 4 May, two groups reported that they had sustained human embryos in vitro for 12-13 days, and this latest advance could lead to scientists being able to study all aspects of early human development with unprecedented precision. (semanticscholar.org)
US-based scientists earlier this month reported they had grown human embryos in the lab for nearly two weeks, for the first time challenging the 14-day rule simply because no one had succeeded in keeping the embryos alive for that long. (medicalxpress.com)
The scientists then destroyed the embryos in order to avoid breaching the two-week limit. (medicalxpress.com)
Scientists warn that compounds released into the embryos environment during their division could negatively affect the potential of the embryo pool. (institutobernabeu.com)
In fact, a team of scientists at the Francis Crick Institute in London [ 1 ] has just applied for permission to use CRISPR/Cas9 on human embryos. (medscape.com)
That makes this only the second time scientists anywhere have edited viable embryos-if that's indeed what Mitalipov did. (wired.com)
While researching embryonic stem cells, scientists at the UNC School of Medicine discovered that by housing a protein called Bax in its active form in the Golgi, embryonic stem cells are primed to kill themselves if damage to their DNA makes them a threat to the developing embryo. (scitechdaily.com)
Scientists have cloned human embryos in test tubes in order to harvest stem cells, but Zavos has done what is considered taboo -- actually implanting the embryos. (go.com)
Did Scientists Recreate a Tyrannosaurus Rex Embryo from Chicken DNA? (snopes.com)
Extending the window for embryo research to 28 days would allow scientists to reveal a new in-depth chapter of knowledge about the developmental processes that take place in embryos," he wrote. (wnd.com)
The stem-cells allow scientists to create "synthetic" embryos that mimic early stages of human development. (wnd.com)
Scientists around the world criticized Chinese researcher He Jiankui's experimental editing of DNA in embryos that became twin girls. (wuwm.com)
Nevertheless, most scientists say it's far too early to try to create babies that way since it's unclear how well CRISPR works to edit DNA in a human embryo and whether it's safe. (wuwm.com)
He's announcement prompted some bioethicists and scientists to call for a global moratorium on using CRISPR to edit the DNA in human embryos. (wuwm.com)
Instead, they are calling for more specific guidelines for how scientists could ethically proceed with such research. (wuwm.com)
Several teams of scientists around the world are continuing to conduct research on editing DNA in human embryos, including a group in New York that recently disclosed experiments that are underway. (wuwm.com)

Although there is noted evidence that twin pregnancies result in higher live birth rates according to Reuters, the concept that embryos are helping on another implant in the womb, or " embryo assistance " has yet to be completely proven. (mommyish.com)
Zavos said he would never implant a human-cow embryo into the womb because it would be unethical. (go.com)
During this stage, the embryo is transferred into the womb. (hypnosisdownloads.com)

W ASHINGTON - The organizers of the International Summit on Human Gene Editing left the door open to one of the most controversial uses of that technology, altering human eggs, sperm, or early embryos in a way that allows those changes to be inherited by future generations. (statnews.com)
The work studied a total of 830 embryos from 103 egg and sperm donation cycles without any alteration (normozoospermic) and 97 transfers. (institutobernabeu.com)
Officials at OHSU confirmed that the work took place there, and that it met the university's Institutional Review Board criteria for safeguarding the rights and welfare of subjects involved in human research-presumably the donors of the eggs and sperm, in this case. (wired.com)
The article, which appears in Science and is free to access , comes in the midst of a simmering debate about CRISPR gene editing, a powerful technique for rewriting living genomes, which has already been used at least once in (nonviable) human embryos and inspired calls for a voluntary moratorium on editing human egg, sperm, and embryonic cells. (bio-itworld.com)

The views, opinions and positions expressed by these authors and blogs are theirs and do not necessarily represent that of the Bioethics Research Library and Kennedy Institute of Ethics or Georgetown University. (georgetown.edu)
The Steering Committee on Bioethics of the Council of Europe was mandated to draw up such a protocol and for this purpose organised an important symposium on reproductive technologies and embryo research, in Strasbourg from the 16th to the 18th of December 1996. (bmj.com)
This conference will convene experts in bioethics, stem cell research, embryology, and law to discuss the ethical underpinnings and future scope of the rule. (harvard.edu)

EWTN Mass January 10, 2007: The Destruction of Embryos and the Triumph of Life Fr. (priestsforlife.org)
"We were all an embryo at one point, and we ought to as a society be very careful about being callous about the wanton destruction of embryos, of life," Rove said. (ostroyreport.com)

Emilia Niemiec and Heidi Howard argue that the serious health risks associated with egg donation, the burden placed on the women who undergo this procedure, and the related ethical issues should be acknowledged and considered when discussing potential clinical uses of gene editing and related research. (uu.se)
Fresh vs. frozen embryo transfer: new approach to minimize the limitations of using national surveillance data for clinical research. (cdc.gov)
This study aimed to evaluate the quality of embryos generated by in-vitro matured immature follicles, as a guideline for further clinical decision-making. (eurekamag.com)
The recent results of AIDS Clinical Trials Group Protocol 076, a controlled clinical trial sponsored by the National Institutes of Health in collaboration with the National Institute of Health and Medical Research and the National Agency of Research on AIDS in France, indicate that zidovudine administered to a selected group of HIV-infected women and their infants can reduce the risk for perinatal transmission of HIV by approximately two-thirds. (cdc.gov)
Clinical Futures investigators are international experts in their clinical research related fields and have authored hundreds of pediatric research articles in leading peer-reviewed journals. (chop.edu)
Our objective was to compare the clinical outcomes of frozen-thawed embryo transfer (FET) with and without pretreatment gonadotropin-releasing hormone agonist (GnRHa) in polycystic ovary syndrome (PCOS) patients. (sciencegate.app)
assemblage, for research purposes, of of management activities involving planning, biological material selected on the basis of clinical or implementation, documentation, assessment and biological characteristics. (who.int)
The World Health Organization, through its International Clinical Trials Registry Platform, has developed the ICTRP database to provide patients, family members and members of the public current information about clinical research studies. (who.int)

It was previously thought that there is enough DNA precursors 'from the mother' in early embryos to synthesize DNA in rapidly dividing and growing cells," Mogilner said. (innovitaresearch.com)

Comparison of three non-viral transfection methods for foreign gene expression in early chicken embryos in ovo . (nature.com)
Why are chicken embryos typically the go-to for flu vaccine cultivation? (cdc.gov)

In this study, we aimed to detect PM2.5-induced 8-OHdG and Î³H2AX changes in the heart of zebrafish embryos using an immunofluorescence assay. (bvsalud.org)
The results show that EOM from PM2.5 significantly enhanced 8-OHdG and Î³H2AX signals in the heart of zebrafish embryos . (bvsalud.org)
Here, we present an immunofluorescence protocol for investigating the role of DNA damage in PM2.5-induced heart defects that can be applied to the detection of environmental chemical-induced protein expression changes in the hearts of zebrafish embryos . (bvsalud.org)

It was then endorsed in 1984 by the Warnock committee - established to inquire into the technologies in-vitro fertilisation (IVF) and embryology - in the United Kingdom, and in 1994 by the US National Institutes of Health's Human Embryo Research Panel. (edu.au)

The study , published online July 25 in Developmental Cell, revealed that a mother fruit fly ultimately provides no more than half of the DNA building blocks needed by a rapidly dividing embryo. (innovitaresearch.com)
Sure enough, when the embryo's RNR was given free rein in this manner, new, embryo-driven fabrication of DNA precursors exploded fivefold (which caused other developmental problems for the fly embryos). (innovitaresearch.com)
Beginning with Aristotle, quickening divided the developmental stages of embryo and fetus. (asu.edu)
This method is applicable to other vertebrate embryos and is an important tool with which to address cell and developmental biology questions. (nature.com)
Dr Meiser-Stedman was supported in conducting this research by a Peggy Pollak Research Fellowship in Developmental Psychiatry awarded by the Psychiatry Research Trust. (kcl.ac.uk)
The plant kingdom is characterized by a high level of developmental plasticity, including the ability of plants to form embryos (totipotency) in the absence of fertilisation. (europa.eu)
Ascidians are used as a model for developmental research. (ucsd.edu)

It added: "If, in the process of research, early human embryos or germline cells undergo gene editing, the modified cells should not be used to establish a pregnancy. (statnews.com)
Defects in cervical vertebrae in boric acid-exposed rat embryos are associated with anterior shifts of hox gene expression domains. (greenmedinfo.com)
The promise of other fields the authors explore, like gene therapy and embryonic stem cell research, is still more far-reaching. (bio-itworld.com)
Efficient gene transfer by electroporation of chick embryos in ovo has allowed the development of new approaches to the analysis of gene regulation, function and expression, creating an exciting opportunity to build upon the classical manipulative advantages of the chick embryonic system. (nature.com)

For over 35 years, the "14-Day Rule," prohibiting in vitro experimentation on embryos beyond 14 days, has stood as an ethical line in the sand for embryo research around the world. (harvard.edu)

It is suggested that debates on embryo donation for hESC research should include the views of embryo donors and should consider the social, as well as the moral, status of the human embryo. (semanticscholar.org)

A proposed draft protocol for the European Convention on Biomedicine relating to research on the human embryo and fetus. (bmj.com)
Quickening, the point at which a pregnant woman can first feel the movements of the growing embryo or fetus, has long been considered a pivotal moment in pregnancy. (asu.edu)
The physician must consider the effects of drug exposure on the developing fetus or embryo and acknowledge specific susceptibilities at each point in fetal development, as balanced against the risks of worsening maternal illness. (medscape.com)

Even though several studies highlighted the role of maternal thyroid hormones (THs) during embryo-foetal development, direct evidence of their interaction with embryonic thyroid receptors (TRs) is still lacking. (nih.gov)
Those initial, maternal DNA precursors, the researchers further demonstrated, actually put the brakes on a vital enzyme that the embryo needs to crank out precursors all by itself. (innovitaresearch.com)
We acknowledge that in high-risk situations (e.g. previous history of preterm gestation and poor maternal wellbeing), double-embryo transfer (DET) or triple embryo transfer (TET) ought to be disallowed because of unsuitably high perils. (scirp.org)
Conclusion: In direct pathway somatic embryos were in contact with maternal tissue in a suspensor like structure. (who.int)

In this talk I examine the extent to which this has occurred in the debate on embryo research, and the nature of the input provided by religious groups. (otago.ac.nz)
The objective of this paper is to stimulate academic debate on embryo and fetal research from the perspective of the drafting of a protocol to the European Convention on Biomedicine. (bmj.com)

One of the technical bottlenecks in producing nonhuman primate models is that current assisted reproductive techniques, such as in vitro culture and frozen conservation of multicell-stage embryos, often result in poor embryo quality and subsequently lead to low birth rates. (elsevier.com)
Therefore, our experiments demonstrate that by matching the critical time window in the recipient's reproductive cycle for achieving optimal embryo-uterine synchrony, pronuclear embryo transfer technology can significantly improve the pregnancy rate and live birth of healthy baby monkeys. (elsevier.com)
Main topics covered go from selecting females, design and planning of embryo transfer, heat detection mechanisms, bovine reproductive anatomy, thawing protocols and embryo preservation. (thecattlesite.com)
5. In 2001, France and Germany requested the United Nations General Assembly to develop international conventions on human reproductive cloning, therapeutic cloning and research on stem cells. (who.int)
These findings are also useful for further investigating the underlying mechanism of GnRHa-HRT protocol in improving the reproductive outcomes of elderly patients with RIF.Trial registration:The research protocol was approved by the hospital institutional ethics committee (2021002). (sciencegate.app)

The 1973 Supreme Court case Roe v. Wade was a significant event in the story of fetal personhood-the story of whether embryos and fetuses are legal persons. (asu.edu)
In particular, the carcinogenicity, genotoxicity , and embryo-fetal toxicity, along with the route of excretion were evaluated. (cdc.gov)

Vitrification of oocytes and in vitro produced bovine embryos exposed to cytochalasin B. Brazilian Journal of Veterinary Research and Animal Science , 39 (5), 260-265. (usp.br)
The activities of glucose 6-phosphate dehydrogenase (G6PDH) of the follicular oocytes collected from bovine ovaries and the embryos fertilized in vitro were measured using fluorescence microscope with photomultiplier and photometer attachments. (nii.ac.jp)
Publications] Setsuo Iwasaki, Yasuo Shioya and Tatsuo Nakahara: 'Measurement of glucose 6-phosphate dehydrogenase activity in bovine oocytes and embryos using quantitative fluorescence microscopy. (nii.ac.jp)
And embryos in IVM group were fertilized from IVM immature oocytes. (eurekamag.com)

2017) have added robust cornerstone help to the conclusion that elective-single embryo transfer (e-SET) is very viable at diminishing multiplex-gestation birth rates: a 47% lessening with the utilization of e-SET contrasted and double-embryo transfer (DET) and triple-embryo transfer (TET). (scirp.org)

The findings are important to the understanding of the fundamentals of human development at the earliest stages, which have largely remained a mystery despite the attention given to human embryonic stem cell research. (news-medical.net)
Stem cells, harvested during the first week in embryo development, could be revolutionary in treating many diseases, including Alzheimers, which disproportionately affects women. (feminist.org)
This is also the earliest development of the human's nervous system (brain and spinal cord), at which there is risk of the embryo suffering pain. (edu.au)
Recording and contextualizing the science of embryos, development, and reproduction. (asu.edu)
This development and other advances in in vitro research involving organized, embryo-like cellular structures have raised a number of questions about the rule, its genesis, application, and future scope. (harvard.edu)
For example, studies with mice have shown that the deletion of any of PRC2's components results either in the death of an embryo or severe defects during the critical stages of early development. (berkeley.edu)
The resulting zygote splits into two very early in development, leading to the formation of two separate embryos. (medlineplus.gov)
During embryonic development melanocytes are formed from melanoblasts, which originate in the neural crest and migrate through the developing embryo in order to reach their final position on the body [ 2 ]. (plos.org)
Development of somatic embryos was observed on MS basal+0.50mg/l GA3+1.0 mg/lKn and the maximum plantlets formation was achieved when somatic embryos (directly and indirectly induced) were shifted to half strength MS basal medium. (who.int)
In birds, prenatal sounds can also provide anticipatory cues to embryos on postnatal conditions and adaptively direct development. (biologists.com)
Research Fellow of the National Council for Scientific and Technological Development, CNPq, Brazil. (scielo.org.mx)

Privately funded researchers will harvest the cells, and no embryo donors will receive payment. (feminist.org)

A controversial fertility doctor claims to have cloned human embryos and implanted them into four women's wombs.And while none of 11 embryos he claims to have cloned resulted in a viable pregnancy, Dr. Panayiotis Zavos said he'll continue trying to clone a human embryo. (go.com)
We investigated whether pronuclear embryo transfer can be used as an effective means for improving pregnancy and live birth rates of nonhuman primates. (elsevier.com)
The odds of developing hypertensive disorders in pregnancy after fresh vs. frozen embryo transfers compared to natural conception were adjusted for variables such as birth year and the mother's age. (miragenews.com)
In the population analysis, women whose pregnancy was the result of a frozen embryo transfer were 74% more likely to develop hypertensive disorders in pregnancy compared to those who conceived naturally. (miragenews.com)
Among women who had both a natural conception and an frozen embryo transfer IVF conception (the sibling comparison), the risk of hypertensive disorders in pregnancy after frozen embryo transfer was twice as high compared to pregnancies from natural conception. (miragenews.com)
Future research should investigate which parts of the frozen embryo transfer process may impact risk of hypertension during pregnancy. (miragenews.com)
Ongoing pregnancy rate (OPR) at 20 weeks' gestation per embryo transfer. (nih.gov)
PGT-A did not improve overall pregnancy outcomes in all women, as analyzed per embryo transfer or per ITT. (nih.gov)
The ability of tubal transfer of an embryo to produce pregnancy and live birth was first demonstrated in a non-human primate model [1]. (who.int)
The Organization of Teratology Information Specialists is a network of risk-assessment counselors in the United States and Canada who specialize in researching and communicating the risks associated with drug exposures in pregnancy. (medscape.com)

The Obama administration on Wednesday asked an appeals court for an emergency stay that would lift the ban on federal funding of research involving human embryonic stem cells. (news-medical.net)
The research was conducted by Shoukhrat Mitalipov, the same guy who first cloned embryonic stem cells in humans. (wired.com)
The hair-trigger suicidal response is an important adaptation for embryonic stem cells, said the UNC School of Medicine researcher, because a slower response could allow DNA damage to proliferate and harm the embryo. (scitechdaily.com)

Importantly, we observed that the highest live birth rate of ≈64% was obtained when the transfer of pronuclear embryos was performed in the presence of new corpus luteum in the ovary of recipients between 24 h and 36 h after estradiol peak. (elsevier.com)
Should we transfer poor quality embryos? (biomedcentral.com)
To evaluate if it is safe and effective to transfer poor quality embryos. (biomedcentral.com)
Standard morphology assessment has always been the major tool for selecting the best embryo for transfer, and good embryo morphology remains one of the main predictors for the successful outcome of the IVF programs. (biomedcentral.com)
Randomization for single frozen-thawed embryo transfer with embryo selection based on PGT-A euploid status versus morphology. (nih.gov)
Post hoc analysis of women aged 35-40 years showed a significant increase in OPR per embryo transfer (51% [62/122] vs. 37% [54/145]) but not per ITT. (nih.gov)
There was a significant increase in OPR per embryo transfer with the use of PGT-A in the subgroup of women aged 35-40 years who had two or more embryos that could be biopsied, but this was not significant when analyzed by ITT. (nih.gov)
single-embryo transfer. (nih.gov)
A series of training days are scheduled dealing with embryo transfer to assist technicians with selecting and breeding cattle. (thecattlesite.com)
While some expanded peril is natural for the barren populace requiring treatment, the act of multiple embryo transfer adds to these inconveniences and results, particularly concerning its part in higher number pregnancies. (scirp.org)
The Israeli researchers aimed to discover whether hypnosis could make the embryo transfer stage of IVF more successful. (hypnosisdownloads.com)
Transfer of manipulated embryos into pseudo-pregnant foster mice. (irbbarcelona.org)
Biorepositories vary agreement between the provider of research materials considerably, ranging form formal organisations and the recipient of the materials, setting forth to informal col ections of materials in an individual conditions of transfer and use, protecting proprietary researcher's freezer. (who.int)
Frozen Embryo Transfer in IVF--As Good as Fresh? (medscape.com)

Amid a demand for experimentation on older human embryos, bioethicists in Europe are arguing for an extension of the "14-day rule," which prohibits the use of embryos beyond that age. (wnd.com)

The embryos with morphological grade 1 have the lowest aneuploidy frequency (16.6%), and increase by the grade, especially in IVF group. (eurekamag.com)
IVM does not affect the quality of embryos and does not increase the aneuploidy rate of embryos. (eurekamag.com)

Fraser, S., Keynes, R. & Lumsden, A. Segmentation in the chick embryo hindbrain is defined by cell lineage restrictions. (nature.com)
adalimumab decreases effects of rabies vaccine chick embryo cell derived by pharmacodynamic antagonism. (medscape.com)
alefacept decreases effects of rabies vaccine chick embryo cell derived by pharmacodynamic antagonism. (medscape.com)

and more than 18,000 pregnancies were frozen embryo transfers. (miragenews.com)
The embryo selected for e-SET might be from a prior IVF cycle (e.g., cryopreserved embryos (frozen)) or from the present fresh IVF cycle that yielded more than one embryo. (scirp.org)

Reuters also points to an additional study from a fertility center in Iowa that saw no decline in successful pregnancies after instating a single-embryo policy. (mommyish.com)
The patient later had 4 transvaginal IVF embryo transfers, resulting in 3 pregnancies and 4 children. (medscape.com)

Frist said in October 2004, in an apparent reference to the fact that even stem cell researchers have admitted that embryo research is failing to offer progress on finding cures, "It is cruel to people who have disabilities and chronic diseases, and, on top of that, it's dishonest. (lifesitenews.com)
Embryonic stem cell research is seen to be a potentially far more lucrative source of financial profit for researchers and drug companies than adult stem cell research which does not involve selling stem cells and does not require subsequent life-time use of anti-rejection drugs. (lifesitenews.com)
In the journal Obstetrics and Gynecology , researchers posited that weaker embryos that would otherwise die "receive support" from their stronger counterpart. (mommyish.com)
Researchers in North Carolina have created "the first fully living dinosaur embryo in millions of years" using DNA from chicken skin. (snopes.com)
A 68 million-year-old DNA sample retrieved from soft tissue cells found in a recently excavated pregnant Tyrannosaurus Rex fossil has led researchers at North Carolina State University to produce the first fully living dinosaur embryo in millions of years. (snopes.com)
The researchers also plan to bring in two educators - one from the Chesapeake Bay Governor's School, one from Maine - who can develop lesson plans based on the research and get the community involved. (pilotonline.com)
Drinking pomegranate juice, the kind found in any supermarket, could reduce the risk of embryos developing brain damage, according to a new joint study by researchers from Rambam Health Care Campus and the Technion - Israel Institute of Technology, published in the American Journal of Obstetrics & Gynecology. (rambam.org.il)

Instead, we should foster all of these methods, and we should adequately fund and have ethical oversight over all ethical stem cell research. (issues2000.org)

It took 276 failed attempts to implant a cloned embryo to end up will Dolly the Sheep.Zavos said he will to continue his research in order to reach his goal. (go.com)
Scanning electron micrograph of a 6 day old human embryo beginning to implant into the lining of the uterus (endometrium). (ucsd.edu)

The latest study is the first to describe the results of using CRISPR in viable human embryos, New Scientist can reveal. (georgetown.edu)
Editing viable human embryos is, if not exactly a no-no, at least controversial. (wired.com)
Zavos took cells from the morgue and fused them with a cow's egg to create what he said was a viable embryo. (go.com)

The UK's Human Fertilisation and Embryology Authority has decided not to rule on licence applications for research proposals using hybrid embryos until there has been a "full and proper public debate" on the issue. (pharmatimes.com)
There was a question mark over whether the HFEA even had the authority to rule on the use of hybrid embryos, while the government has proposed banning the technique in its recent White Paper on overhauling the Human Fertilisation and Embryology Act 1990. (pharmatimes.com)
The Netherlands will change its laws on embryonic research, which until now only allowed tests to be conducted on leftover embryos procured from in vitro fertilisation processes. (medicalxpress.com)
In vitro fertilisation will reduce the cost of embryos, enabling more producers to access the technology, said Dr Diego Ortiz, CORPOICA. (thecattlesite.com)

While this study - which attempted to repair the DNA of six embryos in total - was very small, the results suggest CRISPR works much better in normal embryos than it did in previous tests on abnormal embryos that could not develop into children. (georgetown.edu)
MIT Technology Review reported that, for the first time in the US, a scientist had used Crispr on human embryos. (wired.com)
Knoepfler worries that incautious work like this could lead to political backlash against Crispr more broadly, like what happened to stem cell research in the 2000s under George W. Bush. (wired.com)
In February the National Academy of Sciences produced a report with its first real guidelines for Crispr research. (wired.com)

People have been talking about embryos, fetuses, and their status in science, the law, and society for centuries. (asu.edu)
New Research: Can Pomegranate Juice Reduce Brain Damage in Fetuses? (rambam.org.il)

The group endorsed research on so-called somatic genome editing, in which only affected cells (such as blood cells in the case of sickle-cell disease) have their genome altered. (statnews.com)
We found that in the Caenorhabditis elegans embryo, AB and P 1 cells fated to be somatic tissue and germline, respectively, have different cytokinesis kinetics supported by distinct myosin levels and organization. (biologists.com)
Results: Somatic embryos were observed from both direct and indirect method. (who.int)
Somatic embryos have their own vascular tissues, and can develop new plantlets independently. (who.int)

We present a complete molecular organization of human PRC2 that offers an invaluable structural context for understanding all of the previous biochemical and functional data that has been collected on this complex," says Berkeley Lab biophysicist Eva Nogales, an electron microscopy expert who led this research. (berkeley.edu)
Early ascidian (sea squirt) embryos visualized by differential interface contrast (DIC) microscopy. (ucsd.edu)

The physician must also be sensitive to, and respect, the moral and ethical principles of patients, and refrain from the use of donated gametes or embryos when it would conflict with legal or ethical restrictions or the moral principles of the patients. (wma.net)

Optimized for transgenic mouse research, with state-of-the-art manipulator technology for microinjection at extremely flat angles. (pasteur.fr)
In vivo, β-gal staining, absent until embryonic day 9.5-10.5 (E9.5-E10.5), was observed as early as E11.5-E12.5 in different primordia (i.e. central nervous system, sense organs, intestine, etc.) of the TRE2× transgenic embryos, while the foetal thyroid function (FTF) was still inactive. (nih.gov)
No β-gal staining was detected in embryos of hypothyroid transgenic mice. (nih.gov)

Using RACE, we automatically reconstructed cellular-resolution tissue anisotropy maps across developing Drosophila embryos and quantified differences in cell-shape dynamics in wild-type and mutant embryos. (janelia.org)
And then she tried again to get King to just hear how far adult-tissue research has already advanced. (cbc-network.org)
a quantity of tissue, blood, urine or removes liability on the part of the provider that other biological y derived material used for diagnosis might arise from the recipient's use of the research and analysis. (who.int)

Microgravity effects on musculoskeletal tissues in embryos and adults. (msm.edu)

Germ-line engineering is changing the genetics in an embryo. (medscape.com)
We should not be doing germ-line engineering in human embryos first before we do them in the animal embryos. (medscape.com)
We believe that scientific understanding and precision in legal definitions of what constitutes a human embryo and/or its germ line are essential to developing coherent policies," the authors write. (bio-itworld.com)

Should the 14-Day Rule even apply to research involving the in vitro culture of embryo-like cellular structures? (harvard.edu)

Understanding this, the Bush administration limited public funding for embryo research to those stem cell lines already created from embryos. (lifesitenews.com)
For the first time in France, the sixth team will intend to create stem cell lines from human embryos conceived in the country. (genethique.org)
Voted NO on expanding research to more embryonic stem cell lines. (issues2000.org)

At both stages, embryos can be described as good, fair, or poor depending on their morphological appearance. (biomedcentral.com)

Britain this year granted its first research licence to genetically modify human embryos to a project that will help women who battle to fall pregnant. (medicalxpress.com)
The research found that, indeed hypnosis did seem to greatly increase chances of becoming pregnant. (hypnosisdownloads.com)
He claims another woman is pregnant who received an embryo created the same way, for the same purpose. (wuwm.com)

Using this method, the G6PDH activities of oocytesat germinal vesicle and second metaphase stages and embryos at two-cell to morulae stages were determined. (nii.ac.jp)
During early stages of breakneck growth, a developing embryo must begin to make its own building blocks of DNA after it has exhausted a supply from its mother. (innovitaresearch.com)

Original generations of GloFish® were genetically enhanced as embryos to help detect environmental pollutants and advance scientific research. (liveaquaria.com)

If he is referring to the "ethical bounds" set by the so-called bioethicists who advise governments around the world on crafting public policy on embryo research, he is making a circular argument. (lifesitenews.com)
Bioethicists are in complete agreement that an embryo is not a human person deserving of any legal protection whatever. (lifesitenews.com)

As the U.S. Senate prepares to hold a hearing on human embryonic stem cell research (hESCR), a new public opinion poll shows that a plurality of Americans (47 percent) oppose federal funding of stem cell research that involves destroying human embryos, while only thirty-eight percent (38 percent) support such funding. (news-medical.net)
A three-judge panel of the U.S. Court of Appeals for the D.C. Circuit granted a request from the Justice Department to lift a temporary injunction issued Aug. 23 blocking the funding on the grounds that it violated a law barring funding any research that involves the destruction of human embryos. (news-medical.net)
Our research with this underutilised crop involves linking genetics to nutritional composition of a set of Bambara groundnut cultivars and land races, representing a portion of available global genepool. (edu.au)

Anatomy3

Analytical, Diagnostic and Therapeutic Techniques and Equipment1

Disciplines and Occupations2

Humanities1

Fresh embryo transfer7

Implantation15

Cryopreservation6

Mouse embryos3

Fertilization16

Blastocyst9

Genetic15

Scientists22

Womb3

Sperm4

Bioethics3

Destruction of Embryos2

Clinical8

Early embryos1

Chicken embryos2

Zebrafish embryos3

Human embryo research1

Developmental7

Gene4

Prohibiting in vitro1

Donation1

Fetus3

Maternal4

Debate on embryo2

Reproductive5

Fetal2

Oocytes4

20171

Development11

Donors1

Pregnancy10

Embryonic stem3

Transfer14

Experimentation1

Aneuploidy2

Chick embryo3

Frozen2

Pregnancies2

Researchers7

METHODS1

Implant2

Viable3

Fertilisation4

CRISPR4

Fetuses2

Somatic4

Microscopy2

Gametes1

Transgenic3

Tissue3

Tissues1

Germ-line3

Vitro culture1

Stem cell lines3

Morphological1

Pregnant3

Stages2

Genetically1

Bioethicists2

Involves3