• These lesions characteristically consist of polygonal cells with bland nuclei, abundant cytoplasm and fine eosinophilic cytoplasmic granules. (wikipedia.org)
  • Paraspermatogonia are characterized by voluminous nuclei with irregular clusters of heterochromatin, numerous dilated cisternae of the rough endoplasmic reticulum and small electron-dense granules spread through the cytoplasm. (applesnail.net)
  • We also observe that vaults located in the extreme periphery of the cytoplasm predominately associate with granule-like structures and actin. (caltech.edu)
  • The neutrophils were round, and the cytoplasm contained cytoplasmic granules. (bvsalud.org)
  • Inset-Higher-magnification image of neoplastic myelocytes with abundant cytoplasm filled with eosinophilic granules. (avma.org)
  • They contain well stained cytoplasm with numerous low electron density vesicles and few secretory granules. (uaeu.ac.ae)
  • Thus, in Prussian blue-stained marrow specimens, about 20% to 40% of red cell precursors have one to three very small, pinhead-sized blue granules in the cytoplasm under oil immersion optics, depending on the quality of the preparation. (mhmedical.com)
  • Such phenomenon was represented by severe distention of the cytoplasmic membrane systems (endoplasmic reticulum and Golgi complex) within the pyramidal cells and extensive swelling of the cytoplasm and neuronal processes of the granule neurons. (researchwithrutgers.com)
  • TEM evaluation from the brushed cells included cells with traditional membership cell features, such as 0.3- to 1 1.0-m dense granules and easy endoplasmic reticulum in the apical cytoplasm, and 1:1 to 2 2:1 cytoplasmic to nuclear UMB24 ratio (Figures 1E and 1F). (arcticcirclescotland.com)
  • Degenerative hepatopancreas, necrosis in hepatocytes, severe cytoplasmic vacuolation and disarrangement of hepatic cords in liver of O. niloticus were prominent seen under light microscopy in the laboratory condition, but in field condition elongated hepatocytes with increased nuclei and vacuolation in cytoplasm of hepatocytes were prominent, while TEM study showed degeneration in mitochondria, dilation in rough endoplasmic reticulum, damage in nucleus and appearance of cytoplasmic vacuolation in hepatocytes under laboratory condition. (omicsonline.org)
  • The axonemal microtubules run along the entire length of the cell and emerge from the posterior end forming a tuft of three or more free flagella, The rough endoplasmic reticulum, and the Golgi complex are involved in the production of secretory granules, some of which are later released by exocytosis. (applesnail.net)
  • Compared to the dark cells, the light cells contain a conspicuously poorly stained cytoplasmic ground substance with varying number of rough endoplasmic reticulum cisterns and secretory granules. (uaeu.ac.ae)
  • The mitochondria increase in number and size, accumulate homogeneous matrix, and acquire small, very dense granules. (rupress.org)
  • Intriguingly, cytoplasmic lattices were disorganized, and mitochondria, endoplasmic reticulum, and components of the subcortical maternal complex were mislocalized. (life-science-alliance.org)
  • The large more rounded luteal cell possessed numerous mitochondria and electron dense membrane- bound granules, extensive agranular endoplasmic reticulum and granular endoplasmic reticulum which at times appeared as stacks of closely packed cisternae. (upm.edu.my)
  • These cells differed from the large luteal cells in that they possessed fewer mitochondria and electron dense membrane- bound granules. (upm.edu.my)
  • Electron microscopy revealed lipofuscin granules, secondary lysosomes carrying various cytoplasmic organelles, and disruption of the double membrane structure of mitochondria, and PCR analysis disclosed a deletion in mitochondrial DNA. (elsevierpure.com)
  • Transmission electron microscopic study of gill showed severe damages which included degenerative changes in mitochondria, cellular vacuolation, damage in tubule vascular system, presence of lipid droplets, elongated nucleus, but in case of field experiment dilated mitochondria and cytoplasmic vacuolation were more prominent. (omicsonline.org)
  • In addition, we determined that several nuage proteins localize to spermatogenic cell-specific structures, including mitochondria-associated granules (MAG), granulated bodies (GB), reticulated bodies (RB), and ribosome aggregates (RA) [ 22 - 26 ]. (hindawi.com)
  • Figures 222 (upper) and 223 (lower) from Chapter 7 (Mitochondria) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Mitochondrial matrix granules are located within the space bounded by the inner mitocho. (ucsd.edu)
  • lt;br />Abstract<br />Lysosomes are cytoplasmic compartments that contain many acid hydrolases and play critical roles in the metabolism of a wide range of macromolecules. (blogspot.com)
  • On light microscopic analysis, there is an endomysial accumulation of mononuclear cells, particularly CD8+ T cells (similar to the findings in PM). Other characteristic findings in muscle include vacuoles lined with basophilic granules, eosinophilic inclusions, abnormal microtubular filaments in nuclear and cytoplasmic inclusions, and ragged red fibers. (rheumaknowledgy.com)
  • These cell types might be related to the different stages of secretory granule synthesis and maturation. (uaeu.ac.ae)
  • At birth there are dense irregular cytoplasmic inclusions presumed to be lipide in renal cells, the cytoplasmic granules of Palade are abundant, and there are large round bodies in the cells of the proximal tubules. (rupress.org)
  • The lipide inclusions disappear a few days after birth, and the cytoplasmic granules of Palade diminish in abundance as the cells differentiate. (rupress.org)
  • Figures 293 and 294 from Chapter 10 (Lipochrome Pigment) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. The density of brown cytoplasmic inclusions identified as lipofuscin, or lipochrome pigment incr. (ucsd.edu)
  • Figure 386 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Exocytosis in a mucus-secreting cell from the colon. (cellimagelibrary.org)
  • Figure 388 from Chapter 15 (Cytoplasmic Inclusions) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Mucus-secreting cell from a crypt of rabbit colonic mucosa after stimulation in vitro with acetycholi. (cellimagelibrary.org)
  • LCH, once described as histiocytosis X, is a clonal proliferative disorder of Langerhans cells that stain immunohistochemically with S-100 and CD-1a and demonstrate cytoplasmic Birbeck granules under electron microscopy. (medscape.com)
  • Both malignant and benign versions of the tumor exist, where malignant tumors are characterized histologically by features such as spindling, high nuclear to cytoplasmic ratios, pleomorphism, and necrosis. (wikipedia.org)
  • Electron microscopy revealed extensive neuronal necrosis among the granule cells and many of these necrotic neurons also displayed the phenomenon of karyorrhexis (fragmentation of the pyknotic nuclei). (researchwithrutgers.com)
  • The nucleus has a prominent, electron-dense, granular nucleolus and clumped chromatin. (avma.org)
  • The classical type is a ring sideroblast with large, Prussian blue-stained granules in a circumferential position around the nucleus of the erythroblast. (mhmedical.com)
  • Luxol blue stain showing eosinophil granules reacting with blue color. (oncohemakey.com)
  • Biologists found in early 20th Century that light microscope do have limitations, as subcellular components and cytoplasmic organelles could not be revealed with the light microscope. (austinpublishinggroup.com)
  • Normal red cell precursors have cytoplasmic organelles termed siderosomes that contain aggregated iron-rich ferritin. (mhmedical.com)
  • Under these experimental conditions, the death rate and the general morphology of HTC cells were not affected, as well as most of the cytoplasmic organelles. (biosafety-info.net)
  • Nuclear DNA appeared orthochromatically greenish-yellow, but cytoplasmic RNA was observed to be metachromatically red under the fluorescence microscope. (bvsalud.org)
  • In fact, anatomical laboratories are incomplete without Transmission Electron Microscope. (austinpublishinggroup.com)
  • The limitations of light microscope led to the discovery of electron microscope (EM). (austinpublishinggroup.com)
  • But with the electron microscope we could achieve a resolving power of 0.2 nm that is 1000x better than a light microscope or one million times better than unaided human eye. (austinpublishinggroup.com)
  • The preparation of specimen to be viewed with an electron microscope also needs an expertise. (austinpublishinggroup.com)
  • The ultra structure of luteal cells and the proportion of the different cell types in the functional corpus luteum of the goat were studied using the electron microscope. (upm.edu.my)
  • Students should be able to describe neurons and glia, their morphological components as seen with the light and electron microscope, and some of the fundamental functional roles these cell types play in the nervous system. (comoficar.com)
  • scanning electron microscopic (SEM) and transmission electron microscopic (TEM) results revealed that the ultrastructural features of the blood cells of Zobawng cattle contain certain cellular morphological differences as compared to the other domestic and wild animals. (bvsalud.org)
  • However, the tumor cells contained small secretory granules (up to 250 nm) accumulated along the cell membrane characteristic of thyrotrope cells. (nih.gov)
  • These clusters show preferential accumulation in specific membrane compartments of different cell types, in particular, in Purkinje cell (PC) spines and granule cell (GC) presynaptic active zones. (jneurosci.org)
  • This is in keeping with ultrastructural studies in GCCs that showed the presence of abundant mucinous vacuoles, in comparison with the extremely difficult to locate, occasional membrane-bound, electron-dense granules [ 3 ]. (gastrores.org)
  • Five different types of pituicytes have been identified on the basis of their cytoplasmic characteristics ( 1 ), and attempts are presently underway to characterize and classify each type as a progenitor of a separate type of neurologic tumor. (ajnr.org)
  • Electron microscopy demonstrated a poorly differentiated mesenchymal tumor with a multifocal giant cell component and evidence of neurosecretory-granules. (hindawi.com)
  • Our nuclear transfer experiment showed that the phenotype is attributable to cytoplasmic rather than nuclear defects of the zygotes. (life-science-alliance.org)
  • In contrast, conventional carcinoids are often diffusely positive for chromogranin and synaptophysin, with abundant electron-dense granules on electron microscopy [ 4 ]. (gastrores.org)
  • Transmission electron microscopy has an edge over other optical technologies. (austinpublishinggroup.com)
  • Transmission electron micrograph of a nodule-bearing section of liver from the screech owl in Figure 1 . (avma.org)
  • They can be seen in erythroblasts by transmission electron microscopy and represent normal structures providing iron for hemoglobin synthesis. (mhmedical.com)
  • Cytopathological study both through light and electron microscopic ( scanning electron microscopy and transmission electron microscopy) observations were based on gill, liver and kidney. (omicsonline.org)
  • Transmission electron micrograph of longitudinal section of rat heart ventricle. (ucsd.edu)
  • Transmission electron micrograph of section of cardiac muscle from guinea pig right atrium. (ucsd.edu)
  • Transmission electron micrograph of a section of the right atrium of a guinea pig heart. (ucsd.edu)
  • Furthermore, some adenoma cells were fusiform with long cytoplasmic processes resembling thyrotropes. (nih.gov)
  • Interspersed amongst the large luteal cells were smaller luteal cells with tapering cytoplasmic processes. (upm.edu.my)
  • The collecting ducts develop tight pleating of the basal cell membranes, and dark cells containing numerous small cytoplasmic vesicles and microvilli appear. (rupress.org)
  • Virus isolation and electron microscopy demonstrated virus-infected prairie dogs associated with the recent out- active viral replication in lungs and tongue. (cdc.gov)
  • PRKRA localized to four types of nuage structures, including aggregates of 60-90 nm particles, irregularly-shaped perinuclear granules, and intermitochondrial cement of pachytene spermatocytes, and chromatoid bodies of round spermatids. (hindawi.com)
  • These structures first appear in the cytoplasmic lobe of elongated step 10 spermatids and subsequently disappear in step 19 spermatids. (hindawi.com)
  • The granules are spherical with moderate to high electron density. (avma.org)
  • Scanning electron microscopy displayed severe loss of normal array of concentric microridges, swelling of microridges, damage in epithelial cells and appearance of vacuoles on the stratified epithelium, while loss of regular pattern of microridges were observed under field condition. (omicsonline.org)
  • Phosphoinositides (PIs) are minor components on the cytoplasmic side of eukaryotic cell membranes, but they play essential roles in a wide variety of cellular functions. (jneurosci.org)
  • RISC assembles into processing bodies (P-bodies) which are specific cytoplasmic foci in somatic eukaryotic cells [ 7 - 9 ]. (hindawi.com)
  • The differentiation of the cells of the cortical tubules has been studied using the light and electron microscopes. (rupress.org)
  • To determine if intracellular vaults are morphologically similar to previously studied purified and recombinant vaults, we have used electron cryo-tomography to characterize the vault complexes found in the thin edges of primary human cells growing in tissue culture. (caltech.edu)
  • Viral antigens in the lung were abundant in logic, immunohistochemical (IHC), electron microscopy bronchial epithelial cells, macrophages, and fibroblasts. (cdc.gov)
  • Occasional nuclei of the small luteal cells contained cytoplasmic inclusion bodies. (upm.edu.my)
  • The ultrastructure of pancreatic light and clear endocrine cells in normal and transplanted tissue fragments in the anterior eye-chamber of rats was described by electron microscopy. (uaeu.ac.ae)
  • In order to verify this hypothesis, we treated HTC cells with 1-10 mM Roundup and analysed cellular features by flow cytometry, fluorescence and electron microscopy. (biosafety-info.net)
  • They observed that the big photosynthetic bacteria were killed by tiny cells that attached to their surface and sucked their cytoplasmic content. (nature.com)
  • On the other hand, there are specific cytoplasmic foci similar to the P-bodies in spermatogenic cells, which are called nuage [ 15 - 18 ]. (hindawi.com)
  • Scanning electron micrograph of rat colon mucosa goblet cells. (cellimagelibrary.org)
  • Electron microscopy revealed an undifferentiated, monomorphous adenoma with morphological features of an acidophil stem cell adenoma such as the presence of misplaced exocytoses, fibrous bodies and mitochondrial gigantism. (nih.gov)
  • Figure 427 from Chapter 16 (Cytoplasmic matrix and cytoskeleton) of 'The Cell, 2nd Ed.' by Don W. Fawcett M.D. Papillary muscle of cat heart shows the cross-banded organization of striated muscle. (ucsd.edu)
  • SIGNIFICANCE STATEMENT In this study, we established an electron microscopic method to visualize and analyze the quantitative distribution pattern of phosphatidylinositol-4,5-bisphosphate (PI(4,5)P 2 ) on cell membranes using cryo-fixed brain tissues and SDS-digested freeze-fracture replica labeling. (jneurosci.org)
  • The reticulocytes were recorded occasionally, like small blue thin rods or granules. (bvsalud.org)
  • Nonetheless, muscle biopsy with electron microscopic analysis is required to make a diagnosis of inclusion body myositis. (rheumaknowledgy.com)
  • In such instances, inclusion body myositis should be suspected, and muscle biopsy repeated or reviewed with emphasis on electron microscopic findings. (rheumaknowledgy.com)
  • A variety of renal disorders, carcinomas, neuroendocrine tumors, viral infections and myopathies need electron microscopic exploration to ascertain the cause and pathological features of a diagnostic entity. (austinpublishinggroup.com)
  • Electron optics is a vast subject and could be learnt separately for understanding the functioning of EM and trouble shooting. (austinpublishinggroup.com)
  • The source of illumination used in the EM is high energy 'electron beam' derived from heated tungsten filament or the tip of lanthanum hexabromide (LaB 6 ) crystal. (austinpublishinggroup.com)