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  • needle electrodes
  • Currently, medical researchers are using carbon-based needle electrodes to monitor neurotransmitters. (nanowerk.com)
  • A research team in the Department of Electrical and Electronic Information Engineering and the Electronics-Inspired Interdisciplinary Research Institute (EIIRIS) at Toyohashi University of Technology developed 5-μm-diameter needle-electrodes on 1 mm × 1 mm block modules. (medicalxpress.com)
  • array
  • Flat-panel volume computed tomography for cochlear implant electrode array examination in isolated temporal bone specimens," Otology & Neurotology , vol. 27, no. 4, pp. 491-498, 2006. (hindawi.com)
  • Reliability of cone beam computed tomography in scalar localization of the electrode array: a radio histological study," European Archives of Oto-Rhino-Laryngology , vol. 271, no. 4, pp. 673-679, 2014. (hindawi.com)
  • Imaging of cochlear implant electrode array with flat-detector CT and conventional multislice CT: Comparison of image quality and radiation dose," Acta Oto-Laryngologica , vol. 130, no. 4, pp. 443-452, 2010. (hindawi.com)
  • We used the cochlear implant electrode array for novel "close-field" electroporation to transduce mesenchymal cells lining the cochlear perilymphatic canals with a naked complementary DNA gene construct driving expression of brain-derived neurotrophic factor ( BDNF ) and a green fluorescent protein ( GFP ) reporter. (sciencemag.org)
  • Now, however, scientists have shown in animals that its possible to implant a tiny, ultra-thin electrode array in the auditory nerve that can successfully transmit a wide range of sounds to the brain. (bio-medicine.org)
  • The intimate contact of the array with the nerve fibers achieves more precise activation of fibers signaling specific frequencies, reduced electrical current requirements and dramatically reduced interference among electrodes when they are stimulated simultaneously, Middlebrooks says. (bio-medicine.org)
  • Many of these studies focused on identifying poorly encoding electrodes by some measure (e.g. electrode discrimination, pitch ordering, threshold, CT-guided, masked modulation detection), but provide inconsistent criteria about which electrodes, and how many, should be deactivated, and without considering how speech information becomes distributed across the electrode array. (slesystems.com)
  • Previously validated models were used to generate predictions of speech scores as a function of all possible combinations of active electrodes in a 22-electrode array in three groups of hypothetical subjects representative of relatively better, moderate, and poorer performing CI users. (slesystems.com)
  • Optimal active electrode combinations were those that maximized discrimination of speech cues, maintaining 80%-100% of the physical span of the array. (slesystems.com)
  • The electrode array must fit inside this space. (cochlearimplanthelp.com)
  • As the number of electrodes and wires increases, the wires must either be finer, or the array must become thicker. (cochlearimplanthelp.com)
  • Microscale needle-electrode array technology has enhanced brain science and engineering applications, such as electrophysiological studies, drug and chemical delivery systems, and optogenetics. (medicalxpress.com)
  • A tiny array of implanted electrodes may help people with spinal cord injuries to regain use of their paralyzed limbs, a new study reveals. (neurosciencenews.com)
  • vivo
  • We analyzed the functional consequences of EE on aged brain physiology by performing in vivo local field potential (LFP) recordings with chronic implants. (frontiersin.org)
  • In vivo, 400-micron SIROF electrodes, subjected to 50 Hz, 1 ms current pulses and interpulse bias control for charge-balance, delivered 0.1 mC/phase with electrode polarization well-within safe limits as defined by the potential for water reduction. (arvojournals.org)
  • We demonstrated the high design variability in the packaging of our electrode device, and in vivo neuronal recordings were performed by simply placing the device on a mouse's brain. (medicalxpress.com)
  • H. Sawahata et al, Single 5 μm diameter needle electrode block modules for unit recordings in vivo, Scientific Reports (2016). (medicalxpress.com)
  • entire implant
  • The entire implant system is designed to be wireless, while transmitting as much as 20 megabits of data per second. (medgadget.com)
  • Diamond is so hard and rigid, however, that an entire implant made of the stuff would quickly damage surrounding tissue and the body would seal off the implant as if it were a splinter, Zorman said. (nanowerk.com)
  • minimally invasive
  • A robot-guided minimally invasive approach for cochlear implant surgery: preliminary results of a temporal bone study," International Journal of Computer Assisted Radiology and Surgery , vol. 4, no. 5, pp. 475-486, 2009. (hindawi.com)
  • Neurotology
  • Role of electrode placement as a contributor to variability in cochlear implant outcomes," Otology & Neurotology , vol. 29, no. 7, pp. 920-928, 2008. (hindawi.com)
  • Revision surgery due to magnet dislocation in cochlear implant patients: An emerging complication," Otology & Neurotology , vol. 35, no. 1, pp. 29-34, 2014. (hindawi.com)
  • MRI without magnet removal in neurofibromatosis type 2 patients with cochlear and auditory brainstem implants," Otology & Neurotology , vol. 35, no. 5, pp. 821-825, 2014. (hindawi.com)
  • Hearing preservation outcomes with different cochlear implant electrodes: nucleus hybrid L24 and nucleus freedom CI422," Audiology and Neurotology , vol. 19, no. 5, pp. 293-309, 2014. (hindawi.com)
  • auditory
  • The possible auditory nerve implants likely would be suitable fo. (bio-medicine.org)
  • He led a study requested by the National Institutes of Health to re-evaluate the potential of auditory nerve implants. (bio-medicine.org)
  • The possible auditory nerve implants likely would be suitable for the same people who are candidates today for cochlear implants: the profoundly deaf, who cant hear at all, and the severely deaf, whose hearing ability is greatly reduced. (bio-medicine.org)
  • If the initial success in animals is borne out in further tests, a human auditory nerve implant is probably five to 10 years away, he says. (bio-medicine.org)
  • patient
  • Thus, in cases where the implant is not optimally placed, it is not necessary to remove the implant and then reposition it within or adjacent to the tissue to be treated, thereby reducing stress to the patient caused by additional surgery. (google.com)
  • Postoperative CTs of each patient showed exit of the electrode from the cochlea into the tympanic or labyrinthine Fallopian canal. (ovid.com)
  • prosthetic
  • Draper , an engineering company based in Cambridge, MA, has developed an electrode implant that may drastically improve how amputees control and feel through their prosthetic devices. (medgadget.com)
  • In order to listen to a neuron for long, or help people control a prosthetic as they do a natural limb, the electrodes need to be able to survive for years in the brain without doing significant damage. (umich.edu)
  • surgery
  • Cadaveric feasibility study of da Vinci Si-assisted cochlear implant with augmented visual navigation for otologic surgery," JAMA Otolaryngology-Head & Neck Surgery , vol. 140, no. 3, pp. 208-214, 2014. (hindawi.com)
  • The current surgical setup of cochlear implant surgery is briefly reviewed and its limitations are highlighted. (springer.com)
  • Although this is only a preliminary study, we believe that these results provide a strong indication to the potential of robot-assisted cochlear implant surgery to provide a significant reduction in trauma rates during cochlear implant surgery. (springer.com)
  • The implant is only switched on and stimulated after the eye has recovered fully from the effects of surgery. (implantable-device.com)
  • Bionics
  • After years of hard work and planning, Ms Ashworth's implant was switched on last month at the Bionics Institute, while researchers held their breaths in the next room, observing via video link. (implantable-device.com)
  • Advanced Bionics implants have 16 electrodes, and each one has its own current source (or pair of current sources, if the positive and negative sources are counted separately). (cochlearimplanthelp.com)
  • stimulate
  • An external system is connected to this unit in the laboratory, allowing researchers to stimulate the implant in a controlled manner in order to study the flashes of light. (implantable-device.com)
  • algorithm
  • OBJECTIVE: A retrospective study in 5 patients with pharmacoresistant epilepsy was performed to evaluate whether an elastic image fusion algorithm can provide a more accurate projection of the electrode contacts on the preimplantation magnetic resonance images compared with linear fusion. (uzh.ch)
  • magnetic
  • S. Schmerber, E. Reyt, and J.-P. Lavieille, "Is magnetic resonance imaging still a contraindication in cochlear-implanted patients? (hindawi.com)
  • A contact prepared by the winding of a nanofibre or film material with a relatively high resistivity can effectively suppress turbulence and improve the safety of the electrode during magnetic resonance imaging. (google.com)
  • Magnetic Resonance Imaging (MRI) machines can generate hazardous RF heating of patients with implanted neurostimulation leads. (waikato.ac.nz)
  • frequency
  • Conclusion: Despite the use of a flexible electrode, complete preservation of low frequency residual hearing can only be achieved in a minority of patients. (uni-muenchen.de)
  • We use an electrode with a kilohertz frequency that blocks unwanted nerve conduction in addition to the electrode that stimulates nerve activity," said principal investigator Robert Butera, a professor jointly appointed in Georgia Tech's School of Electrical and Computer Engineering and the Wallace H. Coulter Department of Biomedical Engineering . (gatech.edu)
  • surgical
  • Dr Penny Allen, a specialist surgeon at the Centre for Eye Research Australia, led a surgical team to implant the prototype at the Royal Victorian Eye and Ear Hospital. (implantable-device.com)
  • tissue
  • The resident immune cells spot the foreigner and attack, inflaming the brain tissue and blocking communication between the electrode and the cells. (umich.edu)
  • Other implant devices having micro-electrodes are provided which are especially adapted for electrostimulation and/or electrical monitoring of endo-abdominal tissue or viscera. (google.com)
  • thresholds
  • A positive interpulse bias decreased the polarization of the SIROF electrodes, but was not required to deliver pulses at charge levels above reported chronic perceptual thresholds in humans. (arvojournals.org)
  • devices
  • The next big step will be when we commence implants of the full devices. (implantable-device.com)
  • Microfabricated silicon needle-electrode devices were expected to be an innovation that would be able to record and analyze the electrical activities of the microscale neuronal circuits in the brain. (medicalxpress.com)
  • results
  • With only six weeks of testing, the team couldn't say for sure how the electrode would fare in the long term, but the results were promising. (umich.edu)
  • Several studies have examined the effect of deactivating poorly encoding electrodes on speech perception with mixed results. (slesystems.com)