MetastasesCisplatinTumors by electrochemotherapyIrreversible electroporationCutaneousConclusions ElectrochemotherapyTumoursMelanomaPancreatic cancer cellsChemotherapyIntraoperativeVeterinary oncologyPulsesTreatmentVitroMalignanciesSubcutaneousCalciumHead and neckClinicalTransientTreatmentsCellsTechniqueHighResponse
Metastases3
- First clinical results of electrochemotherapy of internal tumors (e.g. liver metastases) are also promising and encouraging. (wikipedia.org)
- Intraoperative electrochemotherapy of colorectal liver metastases. (slovetres.si)
- AIM: Electrochemotherapy is an effective local treatment for cutaneous tumours and metastases. (unipv.it)
Cisplatin2
- Electrochemotherapy with bleomycin was used to treat a patient for the first time in 1991 at the Institute Gustave Roussy in France, while electrochemotherapy with cisplatin was used to treat for the first time in 1995 at the Institute of Oncology, Ljubljana, Slovenia. (wikipedia.org)
- In the clinical use of electrochemotherapy, limited side effects related to bleomycin or cisplatin use are recorded. (wikipedia.org)
Tumors by electrochemotherapy3
- The effective control of vulvar tumors by electrochemotherapy may contribute to improvement of quality-of-life. (bmj.com)
- Towards treatment planning and treatment of deep-seated solid tumors by electrochemotherapy. (slovetres.si)
- Coupling treatment planning with navigation system: a new technological approach in treatment of head and neck tumors by electrochemotherapy. (slovetres.si)
Irreversible electroporation2
- This review summarizes the use of high-voltage electrical pulses (HVEPs) in clinical oncology to treat solid tumors with irreversible electroporation (IRE) and electrochemotherapy (ECT). (rsna.org)
- 11) Zupanic A, Kos B, Miklavcic D. Treatment planning of electroporation-based interventions: electrochemotherapy, gene electrotransfer and irreversible electroporation. (slovetres.si)
Cutaneous4
- Reduction of tumor size has been achieved with electrochemotherapy faster and more efficiently than in standard chemotherapy for both cutaneous and subcutaneous tumors. (wikipedia.org)
- Curatolo P, Quaglino P, Marenco F, Mancini M, Nardò T, Mortera C, Rotunno R, Calvieri S and Bernengo MG: Electrochemotherapy in the treatment of Kaposi sarcoma cutaneous lesions: A two-center prospective phase II trial. (spandidos-publications.com)
- Benevento R, Santoriello A, Perna G, Canonico S: Electrochemotherapy of cutaneous metastastes from breast cancer in elderly patients: A preliminary report. (karger.com)
- Electrochemotherapy (ECT) is a well-known nonconventional skin cancer ablative method that was shown to be safe and effective for treating both locoregional disease spreading and disseminated cutaneous and subcutaneous lesions from different types of cancer. (unipg.it)
Conclusions Electrochemotherapy2
- Conclusions Electrochemotherapy is an effective and minimally invasive treatment modality in the palliative care management of patients with vulvar cancer. (bmj.com)
- Conclusions Electrochemotherapy could be proposed as a simple, feasible and safe palliative additional treatment in LAPC without progression after chemoradiotherapy. (unibo.it)
Tumours5
- Sersa G, Miklavcic D, Cemazar M, Rudolf Z, Pucihar G and Snoj M: Electrochemotherapy in treatment of tumours. (spandidos-publications.com)
- If Dr Forde and his team find that electrochemotherapy with these drugs triggers a body-wide anti-cancer immune response it could help to ensure that tumours do not reoccur and could reduce the risk of aggressive secondary metastatic cancers. (pcrf.org.uk)
- In this prospective trial, six European institutions investigated electrochemotherapy in recurrent, mucosal head and neck tumours. (unipv.it)
- PATIENT AND METHODS: Forty-three patients with recurrent mucosal head and neck tumours and no further curative or reasonably effective palliative treatment options were enrolled and treated with electrochemotherapy. (unipv.it)
- CONCLUSION: Electrochemotherapy can be applied to mucosal head and neck recurrent tumours accessible to the procedure with promising objective response, survival and toxicity profile. (unipv.it)
Melanoma2
- The main object of this study was a severe melanoma diagnosed in the jaw of a 15-year-old dog and its palliative treatment with electrochemotherapy. (slovetres.si)
- Electrochemotherapy of melanoma: What we know and what is unexplored? (nih.gov)
Pancreatic cancer cells2
- Researchers at CancerResearch@UCC have found that a technique known as electrochemotherapy causes pancreatic cancer cells to become more sensitive to three widely used anti-cancer drugs. (senatormedical.se)
- We found that the electrochemotherapy with these drugs causes the pancreatic cancer cells to die in a way that releases signals into the body that may alter the immune response," said Dr Forde, whose research is published in the journal Cancers . (pcrf.org.uk)
Chemotherapy4
- Electrochemotherapy (ECT) is a type of chemotherapy that allows delivery of non-permeant drugs to the cell interior. (wikipedia.org)
- Cadossi R, Ronchetti M and Cadossi M: Locally enhanced chemotherapy by electroporation: Clinical experiences and perspective of use of electrochemotherapy. (spandidos-publications.com)
- This treatment results in the formation of reversible pores in the cell membrane, allowing up to a 1000 fold increase in chemotherapy drug absorption (Electrochemotherapy). (bmj.com)
- Combination modalities with other immunotherapy agents, chemotherapy, radiotherapy, electrochemotherapy are also being explored to overcome resistance and to potentiate the immune response. (nki.nl)
Intraoperative2
Veterinary oncology2
- Electrochemotherapy in veterinary oncology. (slovetres.si)
- Electrochemotherapy in Veterinary Oncology: State-of-the-Art and Perspectives. (nih.gov)
Pulses5
- Provided that appropriate anesthesia is used for alleviation of the symptoms associated with application of electric pulses, the control of the pain level during the electrochemotherapy is acceptable for the patients. (wikipedia.org)
- Introduction Electrochemotherapy involves the use of transient tumor permeabilization via electric pulses in combination with low-dose chemotherapeutic agents. (bmj.com)
- Electrochemotherapy delivers short, intense pulses of electricity to a tumour, which temporarily increase how porous cancer cells are, allowing more drugs to flood inside. (senatormedical.se)
- Electrochemotherapy is an antitumor treatment that combines a cytotoxic drug with the local administration of electric pulses delivered at the tumor site. (pasteur.fr)
- Electrochemotherapy (ECT) is a combined treatment in which high voltage electroporation (EP) pulses are used to facilitate the uptake of a chemotherapeutic drug into tumor cells, thus increasing antitumor effectiveness of the drug. (biomedcentral.com)
Treatment10
- Recently, new electrochemotherapy modalities have been developed for treatment of internal tumors using surgical procedures, endoscopic routes, or percutaneous approaches to gain access to the treatment area. (wikipedia.org)
- Electrochemotherapy (ECT) may be an option in the treatment of KS skin lesions due to the high response rate noted in neoplastic lesions of different histological types. (spandidos-publications.com)
- One of the treatment options is electrochemotherapy (ECT). (karger.com)
- Background: Electrochemotherapy is becoming a well-established treatment for malignancies of skin and non-skin origin and its use is widening across Europe. (ucc.ie)
- Methods The following databases were searched: MEDLINE, Scopus, and Cochrane Database, to identify all registered articles pertaining to palliative vulvar cancer treatment with electrochemotherapy from inception until August 2019, in line with PRISMA guidelines. (bmj.com)
- What is Electrochemotherapy for cancer treatment? (senatormedical.se)
- 5) Tozon N, Kodre V, G. Sersa G, Cemazar M. Effective treatment of perianal tumors in dogs with electrochemotherapy. (slovetres.si)
- 9) Kos B, Zupanic A, Kotnik T, Snoj M, SerÅ¡a G, MiklavÄiÄ D. Robustness of treatment planning for electrochemotherapy of deep-seated tumors. (slovetres.si)
- These results, which were obtained using allogeneic as well as xenogeneic IL-2-secreting cells, suggest that electrochemotherapy combined with such cellular immunotherapy might be a useful approach for the treatment of metastasizing cancers. (pasteur.fr)
- Electroporation and Electrochemotherapy in Gynecological and Breast Cancer Treatment. (nih.gov)
Vitro1
- The effect of pulse repetition frequency on the uptake into electropermeabilized cells in vitro with possible applications in electrochemotherapy [med. (emf-portal.org)
Malignancies1
- The success rate for electrochemotherapy in "human malignancies" has been stated to be more than 80% provided that a proper patient selection criteria will be performed. (wikipedia.org)
Subcutaneous1
- We previously found that in mice the cure rate of subcutaneous transplanted tumors treated by electrochemotherapy is increased by repeated systemic interleukin-2 (IL-2) injections. (pasteur.fr)
Calcium2
- Electrochemotherapy (ECT) with bleomycin and calcium solution (CaCl2) was combined with standard and CO2 laser surgeries. (slovetres.si)
- a randomized double-blinded phase II study, comparing the effect of calcium electroporation with electrochemotherapy. (bvsalud.org)
Head and neck1
- These favourable results indicate that electrochemotherapy could play a role in patients with recurrent head and neck cancer. (unipv.it)
Clinical4
- The first step, which is addressed in this paper, aims to critically analyze the quality of published studies and to provide the recommendations for reporting clinical trials on electrochemotherapy. (ucc.ie)
- Based on the critical issues emerging from this analysis, recommendations and minimal requirements for reporting clinical data on electrochemotherapy were prepared and summarized into a checklist. (ucc.ie)
- Conclusions: There is an increasing body of published clinical data on electrochemotherapy, but more high quality clinical data are needed. (ucc.ie)
- Our recommendations, provided in the form of a summary checklist, are intended to ameliorate data reporting in future studies on electrochemotherapy and help researchers to provide a solid evidence basis for clinical practice. (ucc.ie)
Transient1
- Electrochemotherapy (ECT) is the combination of transient pore formation following electric pulse application with the administration of cytotoxic drugs, which enhances the cytotoxic effect of the applied agent due to membrane changes. (liverpool.ac.uk)
Treatments3
- Electrochemotherapy treatments. (onkodisruptor.com)
- An overview of the electrochemotherapy sessions on animals, loco-regional anesthetics and intervals for the repetition of veterinary treatments, advice for operators. (onkodisruptor.com)
- He added: "The technology for delivering electrochemotherapy to the pancreas in a patient is still under development, but it is important we unravel the biology to see how these treatments can be refined. (pcrf.org.uk)
Cells3
- This phenomenon is called electroporation (or electropermeabilization) and is becoming widely used to improve anticancer drug delivery into cells, which is being referred to as electrochemotherapy. (wikipedia.org)
- Cemazar M, Parkins CS, Holder AL, Chaplin DJ, Tozer GM and Sersa G: Electroporation of human microvascular endothelial cells: Evidence for an anti-vascular mechanism of electrochemotherapy. (spandidos-publications.com)
- In this study of preestablished tumors in mice we show that after electrochemotherapy, delayed peritumoral injections of histoincompatible IL-2-producing cells result in the cure of almost all the tumors. (pasteur.fr)
Technique2
- Through training, veterinarians can learn the Electrochemotherapy technique and the correct setup of the OnkoDisruptor® electroporators. (onkodisruptor.com)
- Electrochemotherapy technique was consistently reported, with most studies (31/33) adhering closely to published standard operating procedures. (ucc.ie)
High1
- Electrochemotherapy yielded a high nonrecurrence rate of 99.5% for individual sarcoids in the current study. (thehorse.com)
Response1
- Dr Forde hopes to conduct further work examining exactly what effect electrochemotherapy has on the immune response. (pcrf.org.uk)