• We want to help older adults successfully undergo cancer treatment without significant toxicities, so it leads to a survival benefit," she says. (kuer.org)
  • A growing body of evidence supports the notion that cancer care for older adults can be improved with geriatric assessments. (kuer.org)
  • Perphenazine is indicated for use in the treatment of schizophrenia and for the control of severe nausea and vomiting in adults. (nih.gov)
  • Prevalence of potentially inappropriate medication use in older adults living in nursing homes: a systematic review. (ahrq.gov)
  • Although adults aged 65 years and older are still at the greatest risk during the novel coronavirus (COVID-19) pandemic, a new report from the CDC has found that a significant portion of hospitalizations in the United States have come from younger adults. (pharmacytimes.com)
  • Early data from China found that a majority of COVID-19 deaths occurred among adults aged 60 years or older, or among those with underlying health conditions. (pharmacytimes.com)
  • Adults aged 65 years and older are still at the greatest risk, with 31% of cases, 45% of hospitalizations, 53% of ICU admissions, and 80% of deaths. (pharmacytimes.com)
  • The percentage of patients hospitalized increased with age, from 2% to 3% among those less than 9 years old, to 31% or more among adults aged 85 years and older. (pharmacytimes.com)
  • The researchers also found that nearly half of ICU admissions were among adults between 65 and 84 years old. (pharmacytimes.com)
  • Finally, among the 44 cases with a known outcome, 15 (34%) deaths were reported in adults 85 years of age or older, 20 (46%) among adults between 65 and 84 years of age, and 9 (20%) deaths were among adults between 20 and 64 years of age. (pharmacytimes.com)
  • Late-life depression (LLD) is prevalent and defined as major depressive disorder in adults 65 years and older. (psychiatrictimes.com)
  • Furthermore, older adults with LLD tend to have a poor response to treatment with antidepressants, with the remission rates ranging between 55% and 81% in a first-line trial of selective serotonin reuptake inhibitors (SSRIs) or serotonin and norepinephrine reuptake inhibitors (SNRIs). (psychiatrictimes.com)
  • A subpopulation of older adults meet criteria for late-life treatment-resistant depression (LLTRD), defined as failure to respond to 2 or more adequate trials of antidepressant treatment. (psychiatrictimes.com)
  • 13 Additionally, LLTRD is challenging to treat as older adults who have failed 2 previous antidepressant trials are less likely to achieve remission with a third SSRI/SNRI trial. (psychiatrictimes.com)
  • Adherence counseling may be needed for older adults who do not take their medications as prescribed. (psychiatrictimes.com)
  • Several instruments can be used to assess depression severity in older adults with LLTRD, such as the Geriatric Depression Scale and the Beck Depression Inventory. (psychiatrictimes.com)
  • Measurement-based care tends to be efficacious and treatment of depression in older adults is associated with a larger effect size than any single use of antidepressant. (psychiatrictimes.com)
  • LLD often co-occurs with medical comorbidities, and older adults with more significant medical burden often have lower response rates to treatment. (psychiatrictimes.com)
  • 20 For example, physical and functional impairment are significant risk factors for depression , whereas older adults with depression are at a higher risk of subsequent physical decline. (psychiatrictimes.com)
  • The authors noted that the current lack of public policy could lead to an increase in suicide and accidental shootings among baby boomers and older adults, who have high rates of gun ownership and increasing risk for age-related dementia. (osteopathic.org)
  • Researchers report that older adults have the highest rates of gun ownership, with 27 percent of people 65 and older owning one or more firearms, and 37 percent living in a home with a firearm present. (osteopathic.org)
  • Dexamethasone may also be used as a treatment of coronavirus disease 2019 (COVID-19) in adults and adolescents (aged 12 years and older with body weight of at least 40 kg) with difficulty breathing and in need of oxygen therapy. (who.int)
  • Fractional exhaled nitric oxide (FENO) has been extensively studied in children and adults with asthma, but little is known about FENO in elderly asthmatics. (nih.gov)
  • Recently published treatment guidelines that take into account the efficacy and tolerability profiles of new and old antiepileptic drugs (AEDs) provide recommendations for drug selection in adults. (neurology.org)
  • [ 20 ] The JAK inhibitor fedratinib is approved treatment of adults with intermediate-2 or high-risk primary or secondary (post-PV or post-essential thrombocythemia) myelofibrosis. (medscape.com)
  • Ropeginterferon alfa-2b-njft (Besremi) is approved by the US Food and Drug Administration (FDA) for treatment of adults with PV. (medscape.com)
  • Older adults are prone to nutritional deficiencies, especially in situations of stress or disease ( Scheidt, Humpherys & Yorgason, 1999 ). (peerj.com)
  • Pharmacokinetic Studies:  important to determine whether or not the pharmacokinetic behavior of the drug in elderly subjects or patients is different from that in younger adults  to characterize the effects of influences, such as abnormal renal or hepatic function, that are more common in the elderly even though they can occur in any age group. (edocr.com)
  • Social service providers, home caregivers, family members of older adults, and older adults should be trained in medication management and educated about the potential for adverse medication reactions. (cdc.gov)
  • National data sets should be studied further to assess medication-use patterns among older adults. (cdc.gov)
  • Taking DHEA by mouth doesn't improve physical performance in older adults. (medlineplus.gov)
  • Taking DHEA by mouth does not seem to improve mental function or decrease mental decline in healthy older people, people with HIV, or in healthy young adults. (medlineplus.gov)
  • In the largest trial so far to be conducted in frail elderly patients with advanced gastroesophageal cancer, a lower dose of chemotherapy produced similar outcomes but with less toxicity than the standard dose used for patients with this condition. (medscape.com)
  • Many elderly or frail patients are unable to tolerate the standard combination chemotherapy regimen, he said. (medscape.com)
  • Geriatric assessments can help physicians better estimate who will likely develop chemotherapy toxicities and other serious potential complications of cancer treatment, including death. (kuer.org)
  • This paper presents the major issues related to the surgical management of presumed early-stage ovarian cancer, surgery and chemotherapy for advanced-stage ovarian cancer in the elderly, and a proposed 21st century algorithm for dealing with these major issues in ovarian cancer in the elderly. (cancernetwork.com)
  • 7) Renal function is less than optimal in many patients in their 70s and 80s, and thus, cytotoxic chemotherapy has the potential to be more toxic. (cancernetwork.com)
  • These cancers are more frequent in older people who are often too frail to undergo full course of chemotherapy. (ed.ac.uk)
  • This trial brought together researchers and clinicians from multiple centres in the UK to assess whether older and/or frail patients with advanced gastroesophageal cancer benefit from less intensive palliative chemotherapy and whether a formal Geriatric Assessment can assist treatment decision-making. (ed.ac.uk)
  • The article titled " Efficacy of Reduced-Intensity Chemotherapy With Oxaliplatin and Capecitabine on Quality of Life and Cancer Control Among Older and Frail Patients With Advanced Gastroesophageal Cancer - The GO2 Phase 3 Randomized Clinical Trial " presents evidence that reduced-intensity chemotherapy provides a better patient experience without significantly compromising cancer control and should be considered for older and/or frail patients. (ed.ac.uk)
  • Baseline geriatric assessment can help predict the utility of chemotherapy but did not identify a group benefiting from higher-dose treatment. (ed.ac.uk)
  • We hope our findings will help patients make an informed choice between low-dose chemotherapy and no chemotherapy at all, with the knowledge that low-dose chemotherapy may prove beneficial and still allow them to maintain some quality of life while slowing the progression of the disease. (ed.ac.uk)
  • Suppress myeloproliferative activity with chemotherapy (hydroxyurea) in all patients older than 50 years. (medscape.com)
  • thus, evaluate treatment carefully before using any chemotherapy or radiotherapy. (medscape.com)
  • Prophylaxis and treatment of emesis induced by cytostatics, emetogenic chemotherapy within antiemetic treatment. (medicines.org.uk)
  • Standard treatment for advanced disease consists of cytoreductive surgery and combination chemotherapy. (utwente.nl)
  • Bezak Modelling aggressive cancer treatment elderly tumour repopulation aggressive cancer treatment elderly chemotherapy, Physics in Medicine and Biology submis A2. (ceas-mana.ro)
  • Limited single-institution retrospective series suggest that clinically fit elderly patients may benefit from a similar treatment regimen. (jnccn.org)
  • But with the increase in longevity comes a combination of chronic diseases and organ impairments, not all of which are clinically readily apparent in the elderly. (cancernetwork.com)
  • Therefore, it is necessary to predict the sensitive indicators of MACE in elderly CHF patients clinically, which is especially important to improve people's prognosis. (hindawi.com)
  • Routine measurements of FENO may not be clinically valuable in elderly asthmatics. (nih.gov)
  • For drugs used in diseases not unique to, but present in the elderly, a minimum of 100 patients would usually allow detection of clinically important differences. (edocr.com)
  • MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands), published online in the New England Journal of Medicine on December 17, showed a clinically significant increase in functional independence in daily life by 3 months in patients with an occluded major cerebral artery who underwent endovascular intervention, most of whom had already received thrombolysis. (medscape.com)
  • This is the kind of data that oncologists get excited about, and that's being able to give more tolerable treatments with comparable outcomes," said Nicholas Rohs, MD, assistant professor of medicine, hematology, and medical oncology at the Tisch Cancer Institute at Mount Sinai, New York City, who was approached for comment. (medscape.com)
  • Patients in level C experienced fewer side effects and achieved better OTU outcomes than those in level A or B. This was the case even for patients who were younger and less frail. (medscape.com)
  • Clinical outcomes associated with medication regimen complexity in older people: a systematic review. (ahrq.gov)
  • The new CDC report is the first preliminary findings on outcomes among patients with COVID-19 in the United States. (pharmacytimes.com)
  • and level C: 60% of level A doses) using Overall Treatment Utility (OTU) assessment tool to help determine the outcomes. (ed.ac.uk)
  • Our aim was to evaluate survival outcomes in patients aged ≥85 years who undergo PPCI for STEMI. (rcpe.ac.uk)
  • Current treatment modalities do not change these outcomes. (medscape.com)
  • TB surveillance and patient-fund register data were used to evaluate TB treatment outcomes. (who.int)
  • However, financial assistance alone did not improve treatment outcomes for migrant patients. (who.int)
  • According to the New York Times , nursing homes obscure the true prevalence of antipsychotic use by giving some of their elderly dementia patients a phony diagnosis of schizophrenia. (citizen.org)
  • [email protected] Clinical Trials in Geriatrics Nidhi Saxena Xcellon Institute [email protected] Introduction  Those aged 65 years or above  Increase in prevalence of large number of physical and health related problems with age  Increased use of prescription and non-prescription drug  Long duration of treatment and poly-pharmacy is common in elderly  Altered physiological function altering the response of drugs. (edocr.com)
  • Reasons:  Prevalence of many diseases is age related and several may co-exist in the same patient  Adequate response from single drug is not possible  Increased utilization of fixed dose drug combination for the optimum management of a number of conditions. (edocr.com)
  • among males aged 20 years and older, prevalence reaches 67% in Kenya. (who.int)
  • The literature reports a high prevalence of tooth loss among older people 1,2 . (bvsalud.org)
  • An international expert consensus (Delphi Survey) established five symptoms and their severities to define treatment failure to provide adequate relief in patients with chronic constipation. (medscape.com)
  • For the elderly, this population is often accompanied by a variety of diseases, so the clinical symptoms and signs of CHF patients are atypical, and it is difficult to get effective treatment in time, thus increasing the mortality of patients [ 4 ]. (hindawi.com)
  • 17 Thus, a PHQ-9 score of 10 or greater usually indicates that the depressive symptoms are severe enough to initiate a medication or treatment alteration. (psychiatrictimes.com)
  • In stable elderly asthmatic patients, FENO was not elevated and did not correlate with subjects' demographics, comorbidities, treatment, symptoms or spirometric values. (nih.gov)
  • The chiropractor will do what is possible to ease symptoms, but treatment cannot be guaranteed at the first visit. (whatclinic.com)
  • In some cases, there is a miscommunication between the patient and the doctor - whether the doctor misses important health issues from the patient's medical history or the patient does not describe their symptoms accurately. (healthnews.com)
  • Older individuals are also at higher risk of a misdiagnosis because they often have atypical symptoms and have other chronic illnesses with overlapping symptoms that make it harder for a doctor to diagnose a heart attack. (healthnews.com)
  • In some cases, the elderly may not have the typical symptoms of depression, but they instead experience unexplained pain or digestive problems. (healthnews.com)
  • The GERSOC-Trial will evaluate whether geriatric screening in elderly patients with advanced-stage ovarian cancer improves treatment completion and quality of life. (utwente.nl)
  • The life expectancy of elderly patients with glioblastoma is significantly shorter than in younger patients. (jnccn.org)
  • It has the oldest average population in the world and the longest life expectancy. (heartland.org)
  • When the patient is already over 80, the simple fact of the matter is that no amount of treatment is going to work miracles in terms of life expectancy or quality of life. (thedailybeast.com)
  • In general, phosphorus-32 ( 32 P) therapy should be reserved for patients older than 80 years or patients with comorbid conditions in whom life expectancy is less than 5-10 years and the convenience of 32 P dosing outweighs the substantial risks of developing acute leukemia 5-15 years after 32 P administration. (medscape.com)
  • Because the or no cavities) were diagnosed with the elderly population is increasing and the This research was approved by the eth- use of dental explorer and were scored elderly have a longer life expectancy in ics committee of the Suleyman Demirel as "D." Missing teeth were scored as most parts of the world, the number of University School of Medicine. (who.int)
  • This is especially impactful in a disease with a paucity of data, particularly in our elderly or frail patients that comprise a significant portion of patients with this disease," he said. (medscape.com)
  • Hall and his team had previously conducted a phase 2 trial in a similar population of older, frail patients with advanced gastroesophageal cancer and found that the combination of oxaliplatin ( Eloxatin , Sanofi-Aventis) and capecitabine ( Xeloda , Hoffman-LaRoche) was more effective than capecitabine alone. (medscape.com)
  • The goal of the study was to find the optimum dosage of capecitabine and oxaliplatin for use in older or frail patients and to determine the optimal clinical benefit, tolerability, quality of life, and patient satisfaction. (medscape.com)
  • It remains challenging to distinguish fit elderly patients who can endure standard therapy from frail patients who may benefit from an adapted treatment strategy. (utwente.nl)
  • As a comprehensive geriatric assessment (CGA) can contribute to the identification of frail patients and improve tailored therapy in this population, screening tests were developed to select those who may benefit from a CGA. (utwente.nl)
  • These factors and others were incorporated into a novel assessment tool called Overall Treatment Utility (OTU). (medscape.com)
  • Geriatric oncologist Supriya Gupta Mohile meets with patient Jim Mulcahy at Highland Hospital in Rochester, N.Y. "If I didn't do a geriatric assessment and just looked at a patient I wouldn't have the same information," she says. (kuer.org)
  • Before his doctor devised a treatment plan, she ordered what's known as a geriatric assessment. (kuer.org)
  • Geriatric assessment is an approach that clinicians use to evaluate their elderly patients' overall health status and to help them choose treatment appropriate to their age and condition. (kuer.org)
  • The assessment includes questionnaires and tests to gauge the patients' physical, mental and functional capacity, taking into account their social lives, daily activities and goals. (kuer.org)
  • If I didn't do a geriatric assessment and just looked at a patient I wouldn't have the same information," she says. (kuer.org)
  • A study published in the Journal of Geriatric Oncology in November found that in 197 cancer patients 70 years and older, 27% of the treatment recommendations patients received from the tumor board were different from those received after completing a geriatric assessment. (kuer.org)
  • Thus, assessment of autonomic dysreflexia in patients with known causative factors may include palpation of the bladder and bowel and can also include bladder scan. (wikipedia.org)
  • How do men with eating disorders differ from women in terms of assessment and treatment? (psychiatrictimes.com)
  • Takam, E. Bezak, E. Yeoh, L. Marcu Assessment of normal tissue complications following prostate cancer irradiation: comparison of radiation treatment modalities using NTCP models, Medical Physics submisA4. (ceas-mana.ro)
  • We therefore sought to evaluate, through a retrospective multicenter cohort study, whether long-term treatment with acetylsalicylic acid was associated with lower in-hospital mortality in this specific population. (springer.com)
  • An independent expert team identified ADEs present upon admission or occurring during hospitalization by a structured retrospective patient chart review. (springer.com)
  • According to the Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7), the SBP should be the primary target for diagnosis and treatment of hypertension in the elderly ( TABLE 1 ). (uspharmacist.com)
  • Chiropractors specialise in the diagnosis and treatment of nerve, muscle and join problems particularly relating to the spine and its effect of the nervous system. (whatclinic.com)
  • La comanda in aproximativ 4 saptamani Edited by world renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up to date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care. (ceas-mana.ro)
  • It is concluded that although information about diagnosis and treatment does not appear in patients' discourse effectively, participants consider their decision-making autonomy to be valid during treatment. (bvsalud.org)
  • Chiang Rai Hospital (CRH), the largest provincial government hospital, provides free TB diagnosis and treatment for patients who declare that health-care costs are unaffordable. (who.int)
  • This may also lead to more patients being eligible for second-line therapies, as they will be in better clinical condition after finishing their first line of therapy. (medscape.com)
  • Available prospective randomized clinical trials in the elderly population with glioblastoma have shown that radiotherapy is superior to supportive care only, that single-modality hypofractionated radiotherapy (reduced dose and shorter treatment schedule) is an alternative to single-modality standard fractionated radiotherapy, and that single-agent temozolomide is equivalent to radiotherapy alone. (jnccn.org)
  • As patients use conditionally approved therapies outside the standard clinical testing track, the results can be placed in that registry, where names and other private information are shielded from researchers' view. (heartland.org)
  • Expert consensus document on hypertension in the elderly: A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents Developed in collaboration with the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, and European Society of Hypertension. (smw.ch)
  • Furthermore, there is no consensus on clinical indications for various types of pessaries, patient characteristics for sizing, or appropriate pessary care [5,6]. (researchgate.net)
  • Primary care attendees with subclinical as well as clinical insomnia had increased odds of being older and female and having chronic medical illness compared with those without insomnia. (psychiatrist.com)
  • Patients with clinical insomnia had increased odds of common mental disorders (anxiety, depression, and somatization) and greater disability compared with the subclinical or no insomnia groups. (psychiatrist.com)
  • Public and Patient Involvement (PPI) in research is a key focus of our active award, the HRB Irish Network for Children's Clinical Trials (In4kids). (hrb.ie)
  • Methods Clinical data were collected retrospectively on all patients aged ≥85 years who were referred and accepted for PPCI to our centre between 2013 and 2018. (rcpe.ac.uk)
  • Identifying low-risk patients suitable for outpatient management is a clinical and research priority. (bmj.com)
  • Conclusions A novel clinical risk score with good discriminative performance was developed to identify elderly patients with UGIB who were suitable for safe outpatient management. (bmj.com)
  • Clinical Experience:  Geriatric patients should be included in the Phase 3 database (and in Phase 2,at the sponsor's option) in meaningful numbers. (edocr.com)
  • Alzheimer's disease) geriatric patients should constitute the major portion of the clinical database. (edocr.com)
  • The Food and Drug Administration (FDA) should complete development and implementation of proposed guidelines for drugs for use in the elderly, especially elderly subgroups at risk, and should emphasize not excluding persons from participating in clinical trials on the basis of age alone. (cdc.gov)
  • Due to the clinical and pathologic significance of calcium oxalate crystals as seen in this patient, specimens from the sinonasal tract should be evaluated for the presence of these crystals, which may be a surrogate marker for fungal infection and may also independently cause tissue destruction. (bvsalud.org)
  • Patients are requested to visit the hospital biweekly or monthly, depending on their clinical conditions. (who.int)
  • At the conclusion of today's session the participant will be able to describe the current status of influenza activity in the United States, discuss the circulating influenza strains seen this season and the implications for clinicians, discuss the use of influenza diagnostic tests and the role in clinical care and discuss anti-viral treatment implications for patients evaluation treatment and testing. (cdc.gov)
  • Participants Patients from January 2015 to December 2020 for the derivation cohort and from January 2021 to June 2022 for the validation cohort were enrolled in this study. (bmj.com)
  • METHODS AND RESULTS: Using the Danish nationwide registries, all patients admitted with a first-time PE between 2000 and 2020 and discharged alive were included. (bvsalud.org)
  • Willingness to support TB patients was driven by presenting provincial TB epidemiology information, research data on the experience of poor patients and the inspiring experiences of other women volunteers. (who.int)
  • While at CDC Dr. Havers research interests have focused on the epidemiology, prevention, and treatment of influenza. (cdc.gov)
  • This article summarizes published data of current patterns of care in elderly patients and reviews published evidence as it pertains to the benefit of different treatment modalities in elderly patients with glioblastoma. (jnccn.org)
  • 2 While studies have shown that the rates of hypertension in the elderly have not changed since 1999, the number of elderly affected continues to grow due to this aging population. (uspharmacist.com)
  • The pathophysiology behind hypertension in the elderly is a complex process that is not entirely understood, but it is attributed to an increase in peripheral vascular resistance caused by decreased elasticity and increased stiffness due to smooth muscle hypertrophy in arterial walls. (uspharmacist.com)
  • In older patients hospitalized for SARS-CoV-2 pneumonia, we aimed to investigate the association between aspirin use before admission and the risk of in-hospital all-cause mortality. (springer.com)
  • After SIPTW, aspirin treatment was not significantly associated with lower mortality (adjusted hazard ratio: 1.10 [0.81-1.49], P = .52). (springer.com)
  • Observational studies suggest that, similar to atypical antipsychotic drugs, treatment with conventional antipsychotic drugs may increase mortality. (nih.gov)
  • The extent to which the findings of increased mortality in observational studies may be attributed to the antipsychotic drug as opposed to some characteristic(s) of the patients is not clear. (nih.gov)
  • Jyrkkä J, Enlund H, Korhonen MJ, Sulkava R, Hartikainen S. Polypharmacy status as an indicator of mortality in an elderly population. (smw.ch)
  • 2 , 3 Insomnia in the elderly is associated with increased mortality, higher functional limitation, and impaired quality of life. (psychiatrist.com)
  • The objective of this study was to investigate the risk of all-cause mortality, worsening heart failure, venous thromboembolism, and myocarditis associated with the mRNA vaccines in patients with heart failure. (bvsalud.org)
  • Unlike rate trends for the non-elderly, both declines appeared independent of corresponding mortality trends for unintentional poisoning and poisoning of undetermined intent. (cdc.gov)
  • The official decline in the suicide rate between 1987 and 2000 may have been a partial artifact of misclassification of non-elderly suicides within unintentional poisoning mortality. (cdc.gov)
  • Prevention of AD involves educating the patient, family and caregivers of the precipitating cause, if known, and how to avoid it, as well as other triggers. (wikipedia.org)
  • Prevention and treatment of postoperative vomiting, within antiemetic treatment. (medicines.org.uk)
  • Dramatic Growth In Cancer Rates Among US Elderly, Minorities Predicted -- ScienceDaily Dysbiosis bad breath Hpv cancer prevention vaccine Kumar S et al, A randomised trial of radiotherapy 3,97 compared with cisplatin chemo-radiotherapy in patients with unresectable squamous cell cancer of the esophagus, Radiotherapy cancer aggressive radiation Oncology 83 2pp. (ceas-mana.ro)
  • To prevent seasonal flu, the Advisory Committee on Immunization Practices (ACIP) of the US Centers for Disease Control and Prevention (CDC) recommends routine annual influenza vaccination for all persons aged 6 months or older, preferably before the onset of influenza activity in the community. (medscape.com)
  • [ 51 ] The ACIP also publishes recommendations on the use of antiviral agents for prevention and treatment of influenza. (medscape.com)
  • Background Primary percutaneous coronary intervention (PPCI) is the first-line treatment for acute ST-elevation myocardial infarction (STEMI). (rcpe.ac.uk)
  • To determine whether the survival of patients with suspected acute pulmonary embolism (PE) relates to radiological probability of acute PE assessed using lung scintigraphy scans (LSS). (rcpe.ac.uk)
  • Treatment of symptomatic multiple myeloma, acute lymphoblastic leukemia, Hodgkin's disease and non-Hodgkin's lymphoma in combination with other medicinal products. (medicines.org.uk)
  • It is unlikely that intra-arterial treatment will alter the natural history of acute ischemic stroke in the absence of a proximal arterial occlusion, so they probably included many patients who didn't need the therapy," he said. (medscape.com)
  • Patients who have a history of being unable to successfully lose and maintain weight and who meet label indications are candidates for weight loss medications. (medscape.com)
  • If deemed ineffective (weight loss less than 5% at 3 mo) or if there are safety or tolerability issues at any time, it is recommended that the medication be discontinued and alternative medications or referral for alternative treatment approaches be considered. (medscape.com)
  • In patients with type 2 diabetes mellitus who are overweight or obese, antidiabetic medications that have additional actions to promote weight loss (such as glucagonlike peptide-1 [GLP-1] analogs or sodium-glucose-linked transporter-2 [SGLT-2] inhibitors) are suggested, in addition to the first-line agent for type 2 diabetes mellitus and obesity, metformin. (medscape.com)
  • and patients who are using medications that may affect kidney function. (medscape.com)
  • These changes ultimately cause the increasing rates of hypertension and influence the choice of which medications should be utilized for treatment. (uspharmacist.com)
  • The physiologic changes affect the pharmacokinetic parameters of commonly used hypertension medications, sometimes leading to different recommendations when it comes to treatment. (uspharmacist.com)
  • Nonpharmacologic treatment may improve hypertension therapy with medications or prevent the need for medications entirely. (uspharmacist.com)
  • The mean annual cost of medications was $1435.93 (€1286), and preventive treatments accounted for the majority of this cost at $1222.66 (€1095). (ajmc.com)
  • In recent decades, the time and costs required to obtain new medications, treatments, and therapies have increased significantly. (heartland.org)
  • TEDD provides a mechanism for collecting real-world data as patients try different medications or therapies. (heartland.org)
  • Multi-dose drug dispensing, in which patients receive their medications packaged together for each dose (and not separated by individual medication), was associated with higher use of potentially inappropriate medications , but not with an increased rate of drug-drug interactions. (ahrq.gov)
  • Evaluation of older persons' medications: a critical incident technique study exploring healthcare professionals' experiences and actions. (ahrq.gov)
  • Patients may not take their medications daily due to factors such as cognitive dysfunction, poor insight, ambivalence about treatment, worries about medication adverse effects, or the misleading concern that the medications have addictive properties. (psychiatrictimes.com)
  • Older individuals may experience weakness and numbness in the limbs, speech difficulty, dizziness, and confusion, which can also be caused by other illnesses or medications. (healthnews.com)
  • These medications act by suppressing the immune system, leaving the patient exposed to severe infection and at risk of cancer. (hrb.ie)
  • Sectral may interact with allergy treatments (or if you are undergoing allergy skin-testing), clonidine, guanabenz, MAO inhibitors, diabetes medications, heart medications, medicines for asthma or other breathing disorders, cold medicines, stimulant medicines, or diet pills. (rxlist.com)
  • Faculty of Dentistry for routine dental treatment between March 2008 and April 2009 in Isparta, Turkey, were interviewed for demographic data, systemic diseases, and lists of medications. (who.int)
  • 0.001).Dentists must be aware of the dental implications that may arise from systemic diseases and medications and should properly modify elderly patients' treatment accordingly. (who.int)
  • the elderly popula- medications used as they relate to age (OHI) (Greene and Vermillion) and tion grew dramatically in the second and gender. (who.int)
  • Trials are being completed to evaluate the effect of high dose varicella vaccine in reducing the high rates of herpes zoster and postherpetic neuralgia ( 10 , 11 ) in elderly. (cdc.gov)
  • We aimed to evaluate the influence of aneurysm, patient, and rater characteristics on the confidence of visual evaluation of aneurysm coiling and retreatment decisions. (ajnr.org)
  • Twenty-six participants of the Advanced Course in Endovascular Interventional Neuroradiology of the European Society of Neuroradiology were asked to evaluate digital subtraction angiography examinations of patients who had undergone endovascular coiling, by determining the grade of aneurysm occlusion, the change between immediate postprocedural and follow-up angiograms, their level of confidence, the technical difficulty of retreatment, and the best therapeutic approach. (ajnr.org)
  • Furthermore, it is critical to assess adherence to medication and treatment. (psychiatrictimes.com)
  • It is the first FDA-approved medication for PV that patients can take regardless of their treatment history, and the first interferon therapy specifically approved for PV. (medscape.com)
  • Reimbursement patterns should encourage better access to medical care for persons needing complex medication regimens and for isolated patients. (cdc.gov)
  • Community-based programs should strengthen efforts to ensure that older Americans have the information necessary to participate with their health-care providers in medication management. (cdc.gov)
  • No definitive medication protocol specific to SARS has been developed, although various treatment regimens have been tried without proven success. (medscape.com)
  • That regimen proved to be too toxic in this patient population. (medscape.com)
  • We previously compared three-, two-, or one-drug treatments in this patient population and found two drugs were best," Hall explained. (medscape.com)
  • Approximately half of all patients with glioblastoma are older than 65 years and nearly one-quarter are older than 70 years, with a rising incidence of this disease in the elderly population. (jnccn.org)
  • However, no randomized trial has been performed in the elderly population using this regimen. (jnccn.org)
  • As the population grows older, so will the rate of cancer among seniors. (kuer.org)
  • Hypertension has been a well-recognized condition in the elderly for a very long time and is prevalent in over 70% of the elderly population. (uspharmacist.com)
  • The elderly population tends to experience more pronounced side effects and consequences from drug interactions as well. (uspharmacist.com)
  • To our knowledge, it has not yet been established whether long-term aspirin use is associated with improved prognosis in an older comorbid population at very high CV risk hospitalized for SARS-CoV-2 pneumonia. (springer.com)
  • RESULTS: Study population consisted of 633 patients with median age 82 years, median Charlson comorbidity index 2. (smw.ch)
  • Depression affects 1-5% of the general elderly population, 13.5% of older individuals who require home healthcare, and 11.5% of elderly who are hospitalized. (healthnews.com)
  • In all countries, the majority of health care spending goes to the older half of the population distribution in deference to the greater demand for health care services among the elderly. (thedailybeast.com)
  • This study reiterates the need for more awareness with regard to detection and management of insomnia in the elderly population. (psychiatrist.com)
  • I nsomnia is a common but underrecognized problem in the elderly population and is reported to have multiple negative health correlates. (psychiatrist.com)
  • Given the large baby boomer population, how will this influence treatment for aging patients with schizophrenia? (psychiatrictimes.com)
  • The study population consisted of 171 patients: 77 anaemic and 94 non-anaemic. (rcpe.ac.uk)
  • Drug used to treat condition where increased age is a risk factor, older people should be oversampled in studies designed to test there efficacy [email protected] Fact  Elderly population are under-represented in trials of treatments for conditions that predominantly affect older people. (edocr.com)
  • The growing aging of the population and the consequent spread of chronic conditions illustrate the importance of studies on old age and autonomy in medical decision-making. (bvsalud.org)
  • However, limited evidence exists on the safety of the SARS-CoV-2 mRNA vaccines in this patient population. (bvsalud.org)
  • Only the population aged 65 years and older showed a sustained decline in the suicide rate over the entire observation period. (cdc.gov)
  • This work's proposal is to analyse the perception of elders with Multiple Myeloma on their autonomy during treatment at the hematology ambulatory of the Clinics Hospital of the Federal University of Goiás. (bvsalud.org)
  • Cancer Treatment: IMRT Radiation Therapy paraziti 12 Cancer aggressive radiation, chimioterapie şi radiaţii - Traducere în engleză - exemple în română Reverso Context Breast cancer: care advices for the skin affected by the oncology treatment effects Teza -ele de cancer aggressive radiation Deterministic modelling of kinetics cancer aggressive radiation radiobiology of radiation-cisplatin interaction in the treatment of head and neck cancers, Universitatea din Adelaide, Australia, Allen, E. (ceas-mana.ro)
  • Perphenazine has not been shown effective for the management of behavioral complications in patients with mental retardation. (nih.gov)
  • New research from Aarhus University now shows that younger persons newly- diagnosed with type 2 diabetes have significantly poorer health and thus a high risk of delayed complications compared with type 2 diabetes patients who first contract the disease twenty years later in life. (news-medical.net)
  • Seeing early signs of diabetes complications among young patients is very serious, says Anne Bo, master of science in public health science from Aarhus University. (news-medical.net)
  • Like strokes and heart attacks, it requires immediate medical treatment to avoid long-term complications, such as tissue damage, organ failure, or death. (healthnews.com)
  • The elderly are more prone to sepsis and other complications due to their weaker immune systems. (healthnews.com)
  • Fortunately, Japanese policymakers had at hand the right idea at the right time: Free To Choose Medicine (FTCM), an innovative approach developed by Bartley Madden that would create an alternative pathway to traditional government drug certification, granting patients access to safe and promising treatments earlier and allowing physicians and patients to make sounder judgements about the efficacy of treatments. (heartland.org)
  • As expected, there was a lower lung cancer death risk seen for those patients who quit smoking earlier in life, and the risk for those who were former smokers was significantly lower than for those who continued to smoke. (health.am)
  • Besides recurrence status, recommendation of retreatment is significantly influenced by patient age, aneurysm neck width, and characteristics of the therapist. (ajnr.org)
  • In the case of twenty percent of the younger patients, researchers discovered early signs of damage to the kidneys, while seven percent showed signs of eye problems. (news-medical.net)
  • The younger patients are more overweight, have poorer controlled blood sugar levels, higher cholesterol levels and almost the same presence of hypertension. (news-medical.net)
  • This can also contribute to the explanation of the younger patients' proportionately poorer health,' says Anne Bo. (news-medical.net)
  • consider anagrelide in younger patients (aged 50-70 y). (medscape.com)
  • The geriatric subpopulation should be represented sufficiently to permit the comparison of drug response in them to that of younger patients. (edocr.com)
  • Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. (citizen.org)
  • DRUG NAME] is not approved for the treatment of patients with dementia-related psychosis. (citizen.org)
  • CHICAGO, November 26, 2018-Red flag laws allowing for the removal of firearms from people with mental illness need to be widely extended to patients suffering from dementia, according to an article in The Journal of the American Osteopathic Association . (osteopathic.org)
  • One study of patients with dementia or related mental health issues revealed 18 percent lived in a home with one or more firearms. (osteopathic.org)
  • According to the study, the presence of guns did not vary by the degree of dementia, with severely impaired patients as likely to have firearms in their homes as those with mild cognitive impairment. (osteopathic.org)
  • Similar policies could assist physicians and families of patients with dementia, Dr. Galluzzi noted. (osteopathic.org)
  • In addition, Dr. Galluzzi encourages patients and their families to make a plan for transferring ownership of the gun before dementia sets in. (osteopathic.org)
  • In the latest example of poor treatment of Britain's elderly, the family of one of the frail residents claim they were given as little as 30 minutes to choose a replacement home for their dementia-stricken mother. (express.co.uk)
  • 3 Hypertension puts the elderly at greater risk for developing several cardiovascular diseases (CVDs), ranging from myocardial infarction, angina, and cerebrovascular disease to peripheral artery disease and cardiac failure. (uspharmacist.com)
  • 50 CHF patients admitted to the Department of Cardiovascular Medicine of our hospital from January 2021 to December 2021 were selected as the observation group. (hindawi.com)
  • When patients are already affected by type 2 diabetes at such a young age, the damage can develop into blindness, kidney failure or life-threatening cardiovascular diseases, as they must live with the disease for decades. (news-medical.net)
  • patients who are elderly or have cardiovascular compromise should be phlebotomized cautiously, and smaller amounts should be removed. (medscape.com)
  • To explore the application value of N-terminal pro-B type natriuretic peptide (NT-proBNP) combined with neutrophil-to-lymphocyte ratio (NLR) in evaluation of major adverse cardiac events (MACEs) in elderly patients with chronic heart failure (CHF). (hindawi.com)
  • The patient is at a high risk for becoming dependent on laxatives and developing a laxative colon. (medscape.com)
  • Analyses of seventeen placebo-controlled trials (modal duration of 10 weeks), largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1.6 to 1.7 times the risk of death in placebo-treated patients. (nih.gov)
  • We know from previous studies that persons with type 2 diabetes who receive proper treatment have a lower risk of death from heart disease. (news-medical.net)
  • The elderly are at increased risk of heart attack because many have risk factors such as high blood pressure, high cholesterol levels, diabetes, and excess weight. (healthnews.com)
  • Older individuals are at increased risk of misdiagnosis, and they often do not receive treatment. (healthnews.com)
  • in 1986 in a case control study of lung cancer in New Mexico, which compared cases and controls less than 65 years of age to those more than 65 years of age and additionally showed that one decline in lung cancer risk that occurs with smoking cessation in the older person is comparable to that of the young. (health.am)
  • This same study showed that the number of years of smoking is relatively less important than the number of cigarettes smoked per day in determining the risk for lung cancer in those persons 65 and older. (health.am)
  • Patients can be risk-stratified for their risk of thrombosis according to their age and history of thrombosis. (medscape.com)
  • Patients older than 60 years or with a previous history of thrombosis are considered to be high risk. (medscape.com)
  • Patients younger than 60 years and with no prior history of thrombosis are considered low risk. (medscape.com)
  • This study aimed to develop a simple risk score to identify elderly patients with UGIB for whom hospital admission is not required. (bmj.com)
  • This was the first study on the construction of a risk score for upper gastrointestinal bleeding in elderly patients. (bmj.com)
  • use of multiple drugs may be the strongest of several factors that predispose older persons to this excess risk. (cdc.gov)
  • Risk factors for rehospitalization were investigated using cause specific Cox regression models.A total of 55 201 patients were identified. (bvsalud.org)
  • CONCLUSION: Patients with PE have a high risk of rehospitalization, with almost half of patients being rehospitalized within 1 year. (bvsalud.org)
  • Identification of high-risk patients may help target interventions aiming at reducing the risk of rehospitalization. (bvsalud.org)
  • The doctor takes all these factors into account and tallies a score for their patient to help guide their decision-making about the patient's treatment. (kuer.org)
  • Whether it's a question of taking away a person's car or gun, these difficult discussions don't get easier as the patient's mental state deteriorates," says Dr. Galluzzi "It's critical for families to talk about this early and decide on power of attorney so someone can act in the best interest of the patient when they are no longer able to do it for themselves. (osteopathic.org)
  • It makes up one part of the different treatment methods that we can chose between when we decide your treatment plan. (whatclinic.com)
  • METHODS: During a 23-month period, all adult non-trauma patients with an Emergency Severity Index (ESI) of 2 or 3 were prospectively enrolled. (smw.ch)
  • Methods: Patients aged 65 years or older with distal femur fractures of AO/OTA types 33 A2, A3, B1, B2, C1, and C2 were included. (lu.se)
  • METHODS: We conducted a registry-based nationwide cohort study of all Danish patients with MI during 2000 to 2017. (bvsalud.org)
  • The average age of patients at the time of diagnosis of advanced, inoperable gastroesophageal cancer is 75 years, and many are frail," Hall told reporters. (medscape.com)
  • Most use reduced chemo schedules to treat frail and/or elderly gastroesophageal cancer patients, but without a good evidence base to guide them," he said. (medscape.com)
  • The GO2 study was a phase 3 trial that included 514 patients aged 51 to 96 years who had advanced gastroesophageal cancer and were residing in the United Kingdom. (medscape.com)
  • This activity has been designated to meet the educational needs of physicians and nurses involved in the management of patients with cancer. (jnccn.org)
  • When Lorraine Griggs' 86-year-old father was diagnosed with prostate cancer, he was treated with 35 rounds of radiation, though he had a long list of other serious medical issues, including diabetes, kidney disease and high blood pressure. (kuer.org)
  • The tool can play an important role in cancer care, according to clinicians who work with the elderly. (kuer.org)
  • It can be tricky to predict who will be cured, who will relapse and who will die from cancer treatment. (kuer.org)
  • Given that in the 21st century many believe 70 years of age is the new 60 and 80 years of age is the new 70, any article on ovarian cancer in the elderly depends on one's definition of elderly. (cancernetwork.com)
  • ABSTRACT: The incidence of ovarian cancer is highest in women over 70 years old, and the disease is the leading cause of death from gynecologic malignancies in the United States and Europe. (cancernetwork.com)
  • Nevertheless, improving the quality of medical care for elderly women with ovarian cancer continues to be a challenge. (cancernetwork.com)
  • 1] As a result, a significant number of women in their 70s and 80s will present with presumed ovarian cancer, requiring a dramatic change in our approach to "elderly" women with this disease. (cancernetwork.com)
  • Therefore, it is reasonable in the 21st century to define elderly relative to ovarian cancer as women in their 70s and 80s. (cancernetwork.com)
  • 8) Comorbidities in this age group make the management of ovarian cancer in the elderly a true 21st century challenge. (cancernetwork.com)
  • In another case, a 72-year-old male patient with cancer rejected treatment options and ended his life with a gunshot to the head. (osteopathic.org)
  • There is no standard of care for the treatment of advanced gastroesophageal cancer in the United Kingdom, and practices vary widely as to which regimen is used. (ed.ac.uk)
  • This is the largest randomized controlled trial to date specifically investigating frail and/or elderly patients with advanced gastroesophageal cancer, and the results should guide future treatment. (ed.ac.uk)
  • According to a 2014 study published in JAMA Network Open several forms of cancer are among the most common missed or delayed diagnoses in the elderly. (healthnews.com)
  • Each year, tens of millions of people are diagnosed with cancer around the world, and more than half of the patients eventually die from it. (health.am)
  • Background: Approximately 40% of the newly diagnosed patients with advanced ovarian cancer are aged 70 years or older. (utwente.nl)
  • Discussion: This trial aims to gather evidence for the use of geriatric screening in treatment decision-making in elderly patients with advanced ovarian cancer. (utwente.nl)
  • Marcu Efficient Monte Carlo modelling of individual tumour cell propagation for hypoxic head and neck cancer, Physics in Medicine and Cancer aggressive radiation Bezak, I Cancer aggressive radiation Scheduling cisplatin and radiotherapy in the treatment of squamous cell cancer aggressive radiation of the head and neck: a modelling approach, Physics in Cancer aggressive radiation and Biology Bezak, Cancer aggressive radiation. (ceas-mana.ro)
  • Olver Modelling of post aggressive cancer treatment elderly accelerated repopulation in squamous hpv cancer and warts carcinomas, Physics in Medicine and Biology Olver Cisplatin and radiotherapy in the treatment of locally advanced head and neck cancer: a review of their cooperation, Acta Oncologica ISSN x. (ceas-mana.ro)
  • Such an eventuality might occur in patients institutionalized in nursing homes or in chronic care facilities who require medical consultations to rule out conditions that are more serious. (medscape.com)
  • More than 60% of cancers in the U.S. occur in people older than 65. (kuer.org)
  • Stroke is a leading cause of adult disability, the third leading cause of death in the United States, and more likely to occur in the elderly. (healthnews.com)
  • Perphenazine products are also contraindicated in patients with suspected or established subcortical brain damage, with or without hypothalamic damage, since a hyperthermic reaction with temperatures in excess of 104°F may occur in such patients, sometimes not until 14 to 16 hours after drug administration. (nih.gov)
  • The long-term risks of polycythemia vera (PV) include leukemic and fibrotic transformation, which occur in fewer than 5% and 10% of patients, respectively, at 10 years. (medscape.com)
  • This team may include the physician, a psychologist or psychiatrist, physical and exercise therapists, dietitians, and other subspecialists, depending on the comorbidities of the individual patient. (medscape.com)
  • Direct cost of the disease is difficult to pin down due to the numerous comorbidities often associated with CM and the fact that many patients with migraine never approach their physician about the disease. (ajmc.com)
  • We looked for associations between FENO and subjects' demographics, comorbidities, asthma treatment, spirometric values and asthma control test (ACT) scores. (nih.gov)
  • A Multi-Domain Group-Based Intervention to Promote Physical Activity, Healthy Nutrition, and Psychological Wellbeing in Older People with Losses in Intrinsic Capacity: AMICOPE Development Study. (mdpi.com)
  • Heart disease is very prevalent among the elderly, representing the leading cause of death in people over the age of 75 years. (uspharmacist.com)
  • Performance of 3 sets of criteria for potentially inappropriate prescribing in older people to identify inadequate drug treatment. (ahrq.gov)
  • They feel very alone when it comes to tackling a disease that is commonly associated with elderly people. (news-medical.net)
  • Care homes are entrusted to care for some of the most frail and vulnerable older people in our society and moving them at such short notice would have been hugely distressing and such a shock that it would have threatened their health and wellbeing and, for some, even their survival. (express.co.uk)
  • But not only is this health care spending on the elderly the key issue in the federal budget, our disproportionate allocation of health care dollars to old people surely accounts for the remarkable lack of apparent cost effectiveness of the American health care system. (thedailybeast.com)
  • 125 patients (6.19%) were denied permits, including 5 children and 6 elderly persons over 60 years, while 1,004 patients (49.73%) received no response, including 265 children and 116 elderly people over 60 (Palestinian District Liaison office in Gaza). (who.int)
  • Often older people (or not so young? (alternativemedicinecollege.com)
  • DHEA levels seem to go down as people get older. (medlineplus.gov)
  • Taking DHEA by mouth daily for up to 2 years doesn't seem to improve body shape, bone strength, muscle strength, or quality of life in people older than 60 who have low DHEA levels. (medlineplus.gov)
  • Patient safety and ethical implications of healthcare sick leave policies in the pandemic era. (ahrq.gov)
  • Development of a trigger tool to identify adverse events and no-harm incidents that affect patients admitted to home healthcare. (ahrq.gov)
  • Furthermore, the younger newly-diagnosed patients are met by a healthcare sector that is not prepared for the patient group. (news-medical.net)
  • This points towards a need to rethink the way the healthcare sector organizes type 2 diabetes treatment, and not least, how the younger type 2 diabetes patients are met by healthcare professionals,' says Anne Bo. (news-medical.net)
  • This activity reviews the evaluation and management of mitral regurgitation and highlights the role of the healthcare team in evaluating and treating patients with this condition. (nih.gov)
  • If you are a patient please refer your questions to your healthcare provider. (cdc.gov)
  • In a recently published study in The Journal of Headache and Pain, Italian researchers compiled data on 548 patients suffering from chronic and episodic migraines enrolled in a tertiary level headache center to determine overall costs incurred. (ajmc.com)
  • Researchers also stated that by following this method, "it was possible to detect any changes in dosage and class of drugs and, therefore, provide better estimates of the cost of pharmacological treatments. (ajmc.com)
  • Among 2449 patients with known age, the researchers found that 6% were aged 85 years or older, 25% were 65-84 years of age, 18% were 55-64 years of age, 18% were 45-54 years of age, and 29% were between 20 and 44 years of age. (pharmacytimes.com)
  • The Internal Medicine wards were staffed by teams consisting of attending physicians, junior and senior residents, and interns on rotation, caring together for an average of ten adult patients daily. (springer.com)
  • While physicians can alert local authorities if a patient should no longer drive a motor vehicle, no such process exists for firearm owners with cognitive impairment. (osteopathic.org)
  • Aside from public policy, the authors say physicians need to get comfortable talking with patients and their families about guns in the home. (osteopathic.org)
  • The main aim of this review is to let general practitioners and physicians understand what happens to older patients after referral to the renal service. (rcpe.ac.uk)
  • At diagnosis half of the patients have a metastatic tumour and recurrence is very common. (hrb.ie)
  • Potential explanations for this abbreviated survival include differences in tumor biology, reduced use of therapies, enhanced toxicity of treatment, or diminished efficacy of available therapies with increasing age. (jnccn.org)
  • 14 These difficulties associated with LLTRD treatment can be exacerbating for clinicians and their patients and can lead to a sense of hopelessness and resistance to further treatments. (psychiatrictimes.com)
  • Epidemiological profile of geriatric patients admitted to the emergency department of a university hospital localized in a rural area. (smw.ch)
  • The study shows that the group of younger newly-diagnosed patients have a much poorer health situation compared to the older diabetic patients. (news-medical.net)
  • Counsel the patient regarding the appropriate dietary prophylaxis with follow-up visits on an outpatient basis. (medscape.com)
  • The share of inpatient sample cases in all hospital patients living in the catchment area according yields as grossing-up factor for the number of outpatient sample cases per year. (bmj.com)
  • Results Within a 2-year period 2007-2008 a total of 2149 injured patients at the age of 65 years and older received inpatient or outpatient treatment. (bmj.com)
  • The hypothesis was tested that the use of diuretics and RAAS blockade could be associated with an increased incidence of serious conditions in those patients. (smw.ch)
  • Elderly patients with epilepsy face unique treatment challenges, which include age-related reductions in liver or kidney function that may alter drug pharmacokinetics. (neurology.org)
  • Therefore, we conducted a multicenter cohort study with the aim to gain a detailed insight into recognition of ADEs by medical teams in older inpatients. (springer.com)
  • A combination of capecitabine and oxaliplatin is a commonly used regimen in my clinic, and to know that we can reduce doses without sacrificing benefit will allow me to give this therapy to more patients than before," he said. (medscape.com)
  • Patients in level B received 80% of doses given to patients in level A. Patients in level C received 60% of the level-A doses. (medscape.com)
  • The initial and daily doses should always be determined based on individual patient response and disease severity. (medicines.org.uk)
  • Initial dose and duration of treatment depending on the cause and severity, 6-16 mg (up to 24 mg) / day orally, divided into 3-4 individual doses. (medicines.org.uk)
  • Level C produced the best OTU results, owing to lower side effects and better quality of life for the patients who received the lower dose. (medscape.com)
  • Multi-dose drug dispensing and inappropriate drug use: a nationwide register-based study of over 700 000 elderly. (ahrq.gov)
  • Johnell K, Fastbom J. Multi-dose drug dispensing and inappropriate drug use: A nationwide register-based study of over 700,000 elderly. (ahrq.gov)
  • Your health care provider may recommend a change in the dose of other steroid treatments you may be taking, if you are given [CV004 trade name]. (who.int)
  • The dose should be titrated to the individual patient response and disease severity. (medicines.org.uk)
  • Of the 1047 patients with SARS-CoV-2 pneumonia and median age 86 years, 301 (28.7%) were taking aspirin treatment before admission. (springer.com)
  • RESULTS: From 2000 to 2017, 136,293 consecutive patients were identified (63.2% men, median age 69 years). (bvsalud.org)
  • Osteoporosis and osteo arthritis are not contraindications to treatment. (whatclinic.com)
  • Initial treatment involves sitting the patient upright, removing any constrictive clothing (including abdominal binders and support stockings), rechecking blood pressure frequently, and then checking for and removing the inciting issue, which may require urinary catheterization or bowel disimpaction. (wikipedia.org)
  • Initial treatment should always be monotherapy. (neurology.org)
  • Initial treatment of autoimmune disorders like systemic lupus erythematodes. (medicines.org.uk)
  • Some patients, especially elderly individuals, may be too weak to care for themselves alone at home. (medscape.com)
  • 1 It is estimated that the number of persons aged 65 years and older will increase to 72 million by the year 2030, which will in turn result in an increased rate of hypertension among the elderly. (uspharmacist.com)
  • He is undergoing treatment at a private hospital's intensive coronary care unit, especially set up for novel coronavirus patients, the official said. (newindianexpress.com)
  • Butt TF, Branch RL, Beesley L, Martin U. Managing hypertension in the very elderly: effect of adverse drug reactions (ADRs) on achieving targets. (smw.ch)
  • Adverse drug reactions in patients older than 70 years during the heat wave occurred in France in summer 2003: a study from the French PharmacoVigilance Database. (smw.ch)
  • Thus, one important strategy for preventing adverse drug reactions among elderly persons is to limit the number of drugs used. (cdc.gov)
  • The current standard treatment of newly diagnosed, protocol-eligible, nonelderly patients with glioblastoma is based on the randomized prospective EORTC/NCIC study that included patients aged 18 to 70 years with a performance status of ECOG 0 to 2. (jnccn.org)
  • Data from patients' electronic medical records were collected and only patients with EM and CM who underwent continuous treatment in the 2 years prior to January 2019 while at the Regional Referral Headache Center of Rome were included in the study. (ajmc.com)
  • The study cohort comprised 250 patients aged 65 years or older consecutively admitted to Internal Medicine wards of three hospitals in the Netherlands between April and November 2007. (springer.com)
  • Inappropriate drug use in the elderly: a nationwide register-based study. (ahrq.gov)
  • Patient involvement for improved patient safety: a qualitative study of nurses' perceptions and experiences. (ahrq.gov)
  • We can see from the study that the younger sufferers are generally receiving too little treatment. (news-medical.net)
  • She refers to the patients' own experiences which were recorded in connection with the study. (news-medical.net)
  • However, the question of why the group of younger diabetic patients is growing is complex, says Helle Terkildsen Maindal, professor of health promotion at Aarhus University, research manager at the Steno Diabetes Center Copenhagen and last author of the research study. (news-medical.net)
  • QUESTIONS UNDER STUDY: Up to 20% of elderly patients present to the emergency department (ED) with non-specific complaints (NSC), such as "generalised weakness", the majority suffering from serious conditions requiring timely intervention. (smw.ch)
  • Patients presenting to the emergency department with non-specific complaints: The Basel Non-specific Complaints (BANC) Study. (smw.ch)
  • This analysis was based on a subset of subjects enrolled in the Ambulatory Treatments for Leaking Associated with Stress (ATLAS) trial, a randomized multicenter study of the Pelvic Floor Disorders Network. (researchgate.net)
  • Further, correlates of insomnia among elderly subjects in India have only been reported in 1 study 14 from a single institution, hence the findings have limited generalizability. (psychiatrist.com)
  • A total of 822 patients (derivation cohort=606 and validation cohorts=216) were included in this study. (bmj.com)
  • This study presents a new malnutrition screening test for use in elderly women. (peerj.com)
  • The purpose of this study was to compare the functional outcome between immediate full weight-bearing (FWB) as tolerated and partial weight-bearing (PWB) during the first 8 weeks following plate fixation of distal femur fractures in elderly patients. (lu.se)
  • Objective: This study evaluated the effect of age, duration of edentulism, and duration of current complete-denture use on the extent of mandibular movements and on reestablishment of vertical dimension of occlusion in elderly complete-denture wearers. (bvsalud.org)
  • Extent of mandibular movements was assessed using intraoral Gothic arch tracings while the study participants were still wearing their old complete dentures (T0). (bvsalud.org)
  • Conclusion: The study findings show that older age and long-term use of dentures were linked to limited reestablishment of vertical dimension of occlusion and range of mandibular motion. (bvsalud.org)
  • A previous study shows unaffordable travel expense was one of the reasons of patient default. (who.int)
  • Our previous study 4 reported that a majority of TB patients had to borrow money during their TB treatment course (six to nine months). (who.int)
  • Our study shows that intra-arterial treatment works. (medscape.com)
  • With intra-arterial intervention as in our study one in three patients had a good outcome. (medscape.com)
  • To assess insomnia and its health correlates among elderly primary care patients in India. (psychiatrist.com)
  • A multicenter, cross-sectional survey was administered to 1,770 elderly primary care patients from 71 government primary health centers in Kerala, India, from May to December 2016. (psychiatrist.com)
  • Insomnia in the elderly is frequent in primary care patients in India and has multiple negative health correlates. (psychiatrist.com)
  • Primary percutaneous coronary intervention in the very elderly: a realistic intervention? (rcpe.ac.uk)
  • A total of 320 patients aged ≥ 70 years with primary, advanced-stage ovarian carcinoma will be included. (utwente.nl)
  • Her current primary research focuses on influenza anti-viral treatment as well as influenza vaccine effectiveness. (cdc.gov)
  • The injury rate rose sharply in persons at the age of 80 years and older (47.5 per 1000). (bmj.com)
  • Dexamethasone is indicated in the treatment of coronavirus disease 2019 (COVID-19) in adult and adolescent patients (aged 12 years and older with body weight at least 40 kg) who require supplemental oxygen therapy. (medicines.org.uk)
  • [ 19 ] The JAK1/2 inhibitor ruxolitinib is approved for treatment of PV in patients who have had an inadequate response to or are intolerant of hydroxyurea. (medscape.com)
  • These patients have very large clots and [intravenous] tPA alone is often inadequate to clear them. (medscape.com)