Eggs for therapeutic human egg cell. Medical search. Frequent questions

The fusion ultimately gives rise to a microscopic embryo, from which embryonic stem cells can theoretically be derived. (the-scientist.com)
In the best case, an early embryo consisting of a few cells may form, but these are not capable of giving rise to human life, nor hESCs for therapeutic purposes. (the-scientist.com)
The resulting clone developed into a microscopic embryo, which survived long enough for pluripotent stem cell lines to be derived. (the-scientist.com)
The egg then "reprograms" the adult nucleus so that the cell behaves like an embryo but has the genes of the adult cell. (nih.gov)
In another strategy, called therapeutic cloning, the embryo can instead be used to create stem cells that are genetically identical to a patient. (nih.gov)
Since embryonic stem cells have the ability to form virtually any cell type in the body, those taken from a cloned embryo could potentially be used to treat many diseases. (nih.gov)
The early mammalian embryo consists of the extra-embryonic cell layers-the trophoblast and a body of cells called the inner cell mass (ICM), which eventually become the embryo proper. (thefutureofthings.com)
It is also our view that there are no sound reasons for treating the early-stage human embryo or cloned human embryo as anything special, or as having moral status greater than human somatic cells in tissue culture. (wikiquote.org)
increased public sensitivity and awareness together with the development of national regulations of governance of human cloning and embryo research in general. (lifeissues.net)
An in-depth analysis aiming at re-defining this terminology according to the new developments in human embryo research would be highly beneficial . (lifeissues.net)
3. National regulations of governance of human cloning and embryo research in general adopted so far confirm the convergence of views of the refusal to adopt legislation or guidelines permitting reproductive cloning , while they still show variations on the legitimacy of human cloning carried out as part of research agendas. (lifeissues.net)
They developed a 'chicken egg tumour model' in which cultured ovarian cancer cells are transplanted on top of the membrane that surrounds a 10-day-old chicken embryo. (medindia.net)
The biodegradable PMO carrying doxorubicin quickly eliminated the human ovarian tumours without affecting other organs in the chicken embryo. (medindia.net)
But it is perhaps not auspicious to quote him for purposes of the scientific debates on human cloning, because Ramsey agreed with and supported the scientific myth of the "pre-embryo" 47 made famous by Jesuit Richard McCormick and frog embryologist Clifford Grobstein. (lifeissues.net)
Thus, while Ramsey agreed that there is a human being present immediately at fertilization, he did not agree that it was also a human embryo or a human person - the classic "pre-embryo" argument. (lifeissues.net)
The human embryo did not begin until after 14-days, thus the above quote from Saunders would not apply. (lifeissues.net)
Perhaps Ramsey would give other extraordinarily powerful arguments as to why human cloning is unethical, but he obviously would not be able to base it on his unscientific "pre-embryo" position. (lifeissues.net)
6. " ... any living human embryo has the inherent 'potential' to develop into a healthy baby . (lifeissues.net)
Originally the relevant philosophical term was "potency" (or inherent power or capacity conveyed by a specific nature) was used to apply to an already existing substance - such as a new living human embryo. (lifeissues.net)
In that sense, the human embryo would not be even a human being yet, much less a human person. (lifeissues.net)
Thus if by "potential" one means "potency" - i.e., that the early human embryo already exists with a human nature that is already there, and has its own inherent power or capacity (provided by that human nature) to simply grow bigger and bigger through all the usual developmental stages through birth, then such a statement stands as accurate - both scientifically and philosophically. (lifeissues.net)
That is, it would be acknowledging that the human embryo and the human " baby " are the same human being and human person throughout all of his/her development. (lifeissues.net)
On the other hand, if by "potential" one means that the human embryo is not a human being or human person yet , but might be later once it has been born (i.e., a "baby"), then that statement is both scientifically and philosophically incorrect. (lifeissues.net)
Otherwise, such a treaty would not recognize the inherent human nature of the early human embryo or fetus until after birth , and thus cloning them and using them for research - both "therapeutic" and "reproductive" -- would not be banned, and women undergoing "infertility treatments" could surely be put in danger. (lifeissues.net)
Again, Saunders is referring to SCNT as "THE" cloning procedure, when there are many other ways to clone a human being as well, and he is scientifically mis-defining the product of SCNT (i.e., the cloned human embryo). (lifeissues.net)
A little shot of electricity comes next, and if all goes well, a new human cloned embryo comes into being and begins to develop in the same way as a sexually created embryo. (cbc-network.org)
Cloning of a human being" means asexual reproduction by implanting or attempting to implant the product of nuclear transplantation [e.g., an embryo] into a uterus or substitute for a uterus with the purpose of producing a human being. (cbc-network.org)
The zygote undergoes rapid mitotic divisions, the formation of two exact genetic replicates of the original cell, with no significant growth (a process known as cleavage) and cellular differentiation, leading to development of an embryo. (news-medical.net)
Research advocates attack President Bush for "banning stem cell research," while pro-life advocates lament a Republican administration and Congress that have banned nothing-not embryo destruction, not human cloning, not fetal farming, not genetic engineering. (eppc.org)
That is to say, we risk turning developed cells into developing embryos, and thus risk engaging in the very activities of embryo destruction and human cloning that we seek to avoid. (eppc.org)
Before leaving office, President Clinton sought to get around the existing law without actually changing it, by funding research on embryonic stem cells so long as the actual embryo destruction was paid for with private dollars. (eppc.org)
A human female embryo develops around 7 million proto-eggs, known as primordial oocytes. (discovermagazine.com)
During fertilization, the egg and the sperm are supposed to contribute precisely one copy of each chromosome to the embryo. (mbexc.de)

But what is not getting such wide reporting is the use of pluripotent stem cells (as well as many other types of cells and genetic engineering techniques) for reproductive purposes . (lifeissues.net)
Finally, and inexorably, a true professional scientist poses clearly challenging questions to his research colleagues, and to the scientific enterprise in general, about the dubious "scientific" justification for the current rush to clone human beings - for both "therapeutic" and for "reproductive" purposes. (lifeissues.net)
Agreeing with the premise of an earlier article in the same journal, he agrees that we "must not let our debate get completely derailed by vested interests, whether politically or economically motivated", and that the failure to find global agreement on human cloning at the U.N. could result in "reproductive" human cloning [and all the abuses of women that would entail]. (lifeissues.net)
Their 'Human Cloning Prohibition Act of 2002' would prohibit human reproductive cloning by imposing significant criminal and civil penalties in the form of fines (at least $1 million) and up to ten years in prison. (boloji.com)
The time of year when eggs are collected from women's ovaries during fertility treatment makes a difference to live birth rates, according to new research published today (Thursday) in Human Reproduction, one of the world's leading reproductive medicine journals. (news-medical.net)
But we can only wonder about the ethical propriety of producing the first human child with this technique, knowing that the hoped-for newborn would be a reproductive experiment, one that may end initially in numerous fetal failures. (eppc.org)
The mature egg cell, observes Roger Gosden, a reproductive biologist at the University of Leeds in England, is the rarest cell in the human body. (discovermagazine.com)
Now there is hope of leveling the reproductive playing field somewhat--several recent experiments promise to lead to a vast supply of human eggs. (discovermagazine.com)
The purpose of this review is to summarize science-based new treatments for human reproductive failure and future developments. (infertile.com)
With stem cell biology and molecular understanding of reproductive failure, new therapies for previously untreatable infertility are currently on the near horizon. (infertile.com)
This article is part of a Special Issue entitled: Molecular Genetics of Human Reproductive Failure. (infertile.com)
Here, we cover the two main areas that contribute to aneuploidy: (1) factors that influence the fidelity of chromosome segregation in eggs of women from all ages and (2) factors that change in response to reproductive ageing. (mbexc.de)
Reproductive cloning versus germ cell (egg, ovum). (who.int)

This could allow us to create cells that are useful for transplantation for a variety of diseases without the problem of immunological rejection," said Noggle in a press briefing. (the-scientist.com)
These proprietary cells avoid ethical issues associated with use or destruction of viable human embryos and, unlike most other major stem cell types, can be immune matched and be a source of therapeutic cells with minimal rejection after transplantation into hundreds of millions of individuals of differing racial groups. (intlstemcell.com)
However, the Senate bill does allow for therapeutic cloning, known as 'nuclear transplantation', for research on therapies that could cure several serious and life-threatening diseases. (boloji.com)
It is the policy of Washington state that research involving the derivation and use of human embryonic stem cells, human embryonic germ cells, and human adult stem cells from any source, including somatic cell nuclear transplantation , is permitted upon full consideration of the ethical and medical implications of this research. (cbc-network.org)
This condition is either inherited, or it is acquired through the infusion of allogeneic hematopoietic cells during transplantation or transfusion . (zubiaga.org)
The tetragametic state has important implications for organ or stem-cell transplantation. (zubiaga.org)

A couple of studies show some success in generating early microscopic embryos, but this [study] is the first successful pluripotent stem cell line," said Daley. (the-scientist.com)
To achieve this success, Scott Noggle at the New York Stem Cell Foundation Laboratory took a unique approach to the process. (the-scientist.com)
Researchers reported in Nature on November 22, 2007, that they successfully isolated 2 embryonic stem cell lines from cloned embryos made using cells from the skin of an adult rhesus macaque. (nih.gov)
The team that isolated the embryonic stem cell lines was led by Dr. Shoukhrat Mitalipov at Oregon Health and Science University in Portland. (nih.gov)
The stem cells, the researchers showed, could turn into heart or nerve cells in the laboratory, and had other characteristics of established embryonic stem cell lines. (nih.gov)
While regarded by many top scientists as the Holy Grail of medicine, others consider embryonic stem-cell research sacrilegious. (thefutureofthings.com)
Recent advances in the field of stem-cell research are giving hope to millions. (thefutureofthings.com)
Avant-garde approaches to stem-cell therapy may be the first stepping-stones to a bright new future of stem-cell medicine and are emerging in leading laboratories worldwide. (thefutureofthings.com)
The term stem cell can be defined by two very important qualities: the cell has the ability to self-renew and, in a more general sense, the cell has not completed differentiation into its final state. (thefutureofthings.com)
A particular field encouraged by the foundation is stem-cell research, with the great hope that it will result in the ability to get cells to differentiate into neurons and support cells to bridge the gap of a spinal cord injury. (thefutureofthings.com)
International Stem Cell Corporation (OTCBB:ISCO), www.internationalstemcell.com , announced today that its wholly owned subsidiary Lifeline Skin Care, Inc. ("LSC"), has now completed its evaluation of the highly successful trial launch of its new stem cell skin care product line in November and December 2010, and will move forward with its general marketing program. (intlstemcell.com)
Lifeline Skin Care products contain parthenogenetic stem cell extract and were developed by the ISCO research team in collaboration with world recognized cosmetic chemists. (intlstemcell.com)
International Stem Cell Corporation is a California-based biotechnology company focused on therapeutic and research products. (intlstemcell.com)
ISCO is advancing novel human stem cell-based therapies where cells have been proven to be efficacious but traditional small molecule and protein therapeutics have not. (intlstemcell.com)
The cost will be met by the North-East England Stem Cell Institute (Nesci). (progress.org.uk)
Peter Braude, Professor of Obstetrics and Gynaecology at Kings College London, who has also been granted HFEA licences for embryonic stem cell research in the past commented, 'This is a difficult situation because there is a strong need for eggs for research. (progress.org.uk)
American feminists and women's health activists are debating on the difficult issue of human cloning and stem cell research. (boloji.com)
The bill purports to promote stem-cell research, while outlawing the cloning of a human being. (cbc-network.org)
While stem-cell research holds enormous potential for treating or even curing some diseases, the cloning of a human being is morally and ethically unacceptable…Any attempt to clone a human being is in direct conflict with the public policies of this state. (cbc-network.org)
Snuppy was cast under suspicion following revelations that the Korean scientist had fabricated his stem cell research. (blogspot.com)
It brightens the prospects that his team retains the source technologies for stem cell research," Park said. (blogspot.com)
Only two of Hwang's 11 claimed stem-cell lines existed when he submitted his 2005 paper to the journal, Science, the university said on Dec. 23. (blogspot.com)
With private stem cell research, of course! (sicklecellpalmbeach.org)
Stem cell research holds more than hope for cures. (sicklecellpalmbeach.org)
The jury is in on stem cell research. (sicklecellpalmbeach.org)
Stem cell research can offer a cure for your incurable illness. (sicklecellpalmbeach.org)
With private stem cell research a personal cure for an ill patient can be accelerated. (sicklecellpalmbeach.org)
Private stem cell research for the wealthy (that will eventually lead to cures for everyone) has arrived!So now you are all relaxed about your health's future because some countries such as Switzerland and some American states such as California are beginning to endorse stem cell research.We too are excited about this ground breaking research. (sicklecellpalmbeach.org)
An article published in the journal Cell Stem Cell describes the first scientific study to develop blastoids - "synthetic embryos", as they were initially (and incorrectly) called - from bovine pluripotent stem cells (PSCs). (news-medical.net)
This is our sad state of stem cell affairs. (eppc.org)
But if we are to make wise policy the stem cell/cloning arena, we need to step back, sort out the various scientific alternatives and moral issues, and search for a way forward that all citizens can embrace. (eppc.org)
To this end, we offer a detailed analysis of the stem cell/cloning question-where is the science, what are the political alternatives, and what moral obligations should guide us? (eppc.org)
Last May, the House of Representatives passed a bill to create a cord blood stem cell bank, legislation that is likely to become law with virtually unanimous support. (eppc.org)
These moral perils are surely not a reason to oppose adult stem cell research, which deserves vigorous and expanded public support. (eppc.org)
and human spermatogenic stem cell culture to treat azoospermia, and to preserve fertility in pre-pubertal boys undergoing cancer treatment. (infertile.com)
One of the greatest controversies triggered tissue, a stem cell encoding for heart tissue by the rapid pace of evolution in biology, will eventually develop into heart tissue particularly in genomics and biotechnology, and so on. (who.int)
When the nucleus of a stem cell has been the technique of cloning. (who.int)
The con- is removed and replaced by a nucleus of cept of human cloning has long been in the another cell type, the stem cell will then imagination of many scientists, scholars and be reprogrammed to produce the product fiction writers [ 1 ]. (who.int)

Moreover, most early-stage embryos that are produced naturally (that is, through the union of egg and sperm resulting from sexual intercourse) fail to implant and are therefore wasted or destroyed. (wikiquote.org)
The first is that great old standard, "sexual" reproduction, in which sperm meets egg. (cbc-network.org)
In a woman's lifetime perhaps 400 will become full-grown eggs capable of being fertilized by sperm. (discovermagazine.com)
However, human eggs frequently contain an incorrect number of chromosomes - a condition termed aneuploidy, which is much more prevalent in eggs than in either sperm or in most somatic cells. (mbexc.de)
Chimeras are formed from four parent cells (two fertilized eggs or early embryos fuse together) or from three parent cells (a fertilized egg is fused with an unfertilized egg or a fertilized egg is fused with an extra sperm). (zubiaga.org)
It occurs through the fertilization of two ova by two sperm, followed by the fusion of the zygotes and the development of an organism with intermingled cell lines. (zubiaga.org)
Such an organism is called a tetragametic chimera as it is formed from four gametes - two eggs and two sperm . (zubiaga.org)

So you have what are called monoclonal antibodies that target cancer cells. (thenakedscientists.com)

Understanding human [eggs'] ability to reprogram could shed light on improved methods for reprograming," said Noggle. (the-scientist.com)
Two separate research teams have figured out how to "reprogram" cells with just a handful of genes to give them the characteristics of embryonic stem cells. (nih.gov)
As a result, the need to be able to directly reprogram adult cells developed. (ed.ac.uk)
The holy grail of regenerative medicine-whatever one's ethical beliefs about destroying embryos-is to "reprogram" regular cells from one's own body so that individuals can be the source of their own rejection-proof therapies. (eppc.org)

A controversial scheme to extend the practise of 'egg sharing' has been approved by the UK's Human Fertilisation and Embryology Authority (HFEA) to provide greater numbers of eggs for embryonic stem (ES) cell research. (progress.org.uk)

Somatic cell nuclear transfer typically involves the transfer of genomic information from a somatic cell into an unfertilized egg cell whose nucleus has been removed. (the-scientist.com)
Cloning entails taking the nucleus - the compartment that contains the DNA - from an adult cell and putting it into an egg from which the original nucleus has been removed. (nih.gov)

ISCO's core technology, parthenogenesis, results in creation of pluripotent human stem cells from unfertilized oocytes (eggs). (intlstemcell.com)
They must inject themselves daily for four weeks with large doses of hormones to encourage their ovaries to produce numerous mature oocytes while simultaneously suppressing the normal menstrual cycle, which would eject the eggs into the fallopian tubes. (discovermagazine.com)
In human oocytes, chromosomes often segregate incorrectly. (mbexc.de)

While iPSCs avoid the ethical issues surrounding embryonic stem cells, the methods used to derive them sometimes induce mutations in cancer causing genes, making them unsuitable for therapeutic purposes. (the-scientist.com)
While women have always been paid for donating their eggs for in vitro fertilization, ethical guidelines have prevented researchers from paying women for their eggs. (the-scientist.com)
The breakthrough may eventually put to rest the ethical controversy surrounding stem cells. (nih.gov)
Stem cells are at the forefront of medical research and incite some of the most controversial ethical and religious debates worldwide. (thefutureofthings.com)
In particular, scientific developments in areas such as iPS cells open new possibilities of research and, at mid term, of therapeutic applications, but they also bring new ethical challenges and problems requiring further reflection and debate. (lifeissues.net)
The recent desperation to clone human embryos may be seriously undermining accepted ethical principles of medical research, with potentially profound wider consequences. (lifeissues.net)
The HFEA has also announced a public consultation, to run from September until November, to assess the opinion of the British public on the ethical status of egg donation for research. (progress.org.uk)
The bill also applies Federal ethical regulations on human subject research and outlaws the transfer of cloned embryos to a woman's uterus or to any artificial womb. (boloji.com)
But adult stem cells also raise some interesting ethical dilemmas alongside their great therapeutic promise. (eppc.org)

The first pluripotent human embryonic stem cells (hESCs) have been generated from somatic cell nuclear transfer, according to a study published today (October 5) in Nature . (the-scientist.com)

In humans, somatic transfer has been less fruitful-the egg cell quits dividing and often dies after nuclear transfer. (the-scientist.com)

Claims that you could clone individual treatments of human beings to treat common diseases like diabetes, suggests you need a huge supply of human eggs. (wikiquote.org)
Review of Critical Article: Cobbe, 'Why the apparent haste to clone humans? (lifeissues.net)
See Neville Cobbe, "Why the apparent haste to clone humans? (lifeissues.net)
While his tadpoles matured to fully functioning adult frogs at the time, subsequent experiments trying to clone frogs using fully adult cells only produced tadpoles that did not mature. (ed.ac.uk)
However, his results and improved methods inspired researchers at The Roslin Institute to use nuclear transfer to clone sheep and produce Dolly the Sheep, the first animal to be cloned from an adult cell. (ed.ac.uk)
HumanPass Wednesday confirmed fingerprinting traces of Snuppy, Hwang's canine clone, matched those of its somatic cell donor, an Afghan hound named Tai, while they demonstrated disparate mitochondrial genotypes. (blogspot.com)
Unicellular for those cells that are derived from human organisms are primed to replicate (clone) pre-embryos, which seem to have a high themselves by nature. (who.int)

The use of various types of stem cells for research purposes to make disease "models" in the lab for regenerative medicine and for "therapies" to cure sick patients for diseases is constantly in the news. (lifeissues.net)
Ethically, since eventually all such "research" will be applied to people, he cautions against the abuse of women "egg" donors, and against the premature use of vulnerable sick human patients for testing supposedly "patient-specific" stem cells in supposed "therapies", pointing to the obvious violations of standard international research ethics guidelines such clinical trials would necessarily entail. (lifeissues.net)
The chicken egg model has several advantages over existing models, such as mouse models, for testing anti-cancer therapies. (medindia.net)
Thus, a kind of 'regenerative medicine' gives people access to therapies derived from their own cells. (boloji.com)

In the end, the egg cell contained three sets of chromosomes-two from the diploid somatic cell, and one from the haploid egg. (the-scientist.com)
The genetically modified egg now has 46 chromosomes, the full human compliment. (cbc-network.org)
For example, the chimera may have a liver composed of cells with one set of chromosomes and have a kidney composed of cells with a second set of chromosomes. (zubiaga.org)

Phosphatidylcholine a major component of egg lecithin, occurs in all cellular organisms, being one of the important components of the phospholipid portion of the cell membrane. (wikipedia.org)
Cloning in biotechnology refers to processes used to create copies of DNA fragments ( molecular cloning ), cells (cell cloning), or organisms . (wikiquote.org)
Together, Gurdon's and the Dolly team's successes introduced the concept of reprogramming the DNA of specialized cells to be able to make new organisms or new stem cells. (ed.ac.uk)

A breakthrough in somatic cell nuclear transfer opens the possibility of producing human embryonic stem cells with a patient's own genes. (the-scientist.com)
The advance here is the proof that somatic cell nuclear transfer can work [in human cells] and can fully reset the donor cell genome to a pluripotent state," said Harvard Medical School's George Daley , who was not affiliated with the study. (the-scientist.com)
Somatic cell nuclear transfer has shown limited success in animal studies, which have successfully isolated pluripotent cells. (the-scientist.com)
Instead of removing the egg genome prior to nuclear transfer, he and his colleagues added the somatic cell nucleus directly to the intact egg. (the-scientist.com)
Briggs and King were the first to perform cloning by nuclear transfer using eggs and cells from the Northern Leopard Frog, Rana pipiens . (ed.ac.uk)
Gurdon used the technique of nuclear transfer to remove the DNA from a tadpole's intestinal cell and place it into an egg cell. (ed.ac.uk)
The primary cloning technique is called "somatic cell nuclear transfer" (SCNT). (cbc-network.org)
Hwang's stem cells should have been found to be nuclear transferred embryonic stem cells from patients' skin cells. (blogspot.com)

Meanwhile, the ability of the mature egg to transform and begin embryonic development remains fully potent. (cbc-network.org)

Before this new study was published, Nature asked another group of researchers to confirm that the stem cells were genetically identical to the donor skin cells. (nih.gov)
It is hoped that one donor per week will be recruited and that each new recruit will donate six to ten eggs for the research. (progress.org.uk)
The nucleus of a body cell from the DNA donor is removed, and put into the place formerly occupied by the egg's nucleus. (cbc-network.org)
Thus, for a tetragametic human, a wider array of relatives and other persons may be eligible to be an organ donor . (zubiaga.org)

This led to the development of therapeutic cloning as a source for genetically matching replacement cells for patients with degenerative diseases. (ed.ac.uk)
The potential of therapeutic cloning for treating, and perhaps curing, a variety of debilitating diseases demands that the scientific community be allowed to continue this promising work. (boloji.com)
Researchers elucidate the role of cell death in the pathogenesis of different diseases. (news-medical.net)
Already, non-embryonic stem cells are being used to treat a variety of diseases-most notably certain cancers of the blood. (eppc.org)

The Roslin Institute's Lissa Heron is working with genetically modified chickens, meaning that their eggs can produce vital drugs. (thenakedscientists.com)
Although chickens can't be cloned in the same way that mammals can, they can be genetically modified, meaning that their eggs might provide us with a lot more than a tasty breakfast in the future. (thenakedscientists.com)
and there's an easy way of now making the genetically modified chicken so that you produce a lot of whatever protein you want in the eggs. (thenakedscientists.com)

In the case of asexually creating a human, the biotechnologist removes the nucleus from a mature human egg (an oocyte). (cbc-network.org)
Aneuploidy arises as a consequence of aberrant meiosis during egg development from its progenitor cell, the oocyte. (mbexc.de)

Successful replication of ovarian tumors inside chicken eggs heralds a new era for patient-centred cancer treatment, said Fuyuhiko Tamanoi of Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) and colleagues in the US. (medindia.net)
Adult stem cells are easier to control than embryonic stem cells and thus less likely to form tumors. (eppc.org)

And now Washington joins the infamous list with Senate Bill 5594, a thoroughly disingenuous piece of legislation that purports to outlaw the cloning of human beings, but by manipulating language and redefining terms, actually permits human cloning and gestation of the resulting cloned embryos through the ninth month. (cbc-network.org)

This paper outlines the debates prompted through a reproduction mechanism involv- by progress in cloning research, with special ing male and female germ cells. (who.int)

As part of the study, Noggle and his colleagues developed new protocols that allow women to choose between giving their eggs to research or in vitro fertilization programs. (the-scientist.com)
As most women will not donate altruistically, this has left researchers working with the poor-quality eggs rejected from in vitro fertilization. (the-scientist.com)
According to the researcher's new protocols, women are paid to donate, but only later choose whether their eggs should go to research or in vitro fertilization. (the-scientist.com)
a) Note, again, the reference to only sexual human reproduction - "the moment of conception" - i.e., fertilization. (lifeissues.net)
The stem cells in storage at Hwang's laboratories at the university were all derived from the fertility clinic MizMedi's blastocysts, which were generated by in vitro fertilization . (blogspot.com)
When it comes to eggs, though, the success of in vitro fertilization has created a demand far exceeding supply. (discovermagazine.com)

Adult stem cells can be used to accelerate bone or tendon healing , and they can induce cartilage progenitor cells to produce a better matrix and repair cartilage damage . (thefutureofthings.com)

Mutations in 11 genes are linked to aggressive forms of prostate cancer, which may present novel therapeutic and therapy options. (medindia.net)
Kat - So, if that complex biological system is the chicken's egg, how do you get the genes that make the proteins into the chickens? (thenakedscientists.com)

Researchers have been hoping to harness the therapeutic potential of cloning ever since the cloning of Dolly the sheep in 1997. (nih.gov)
Therapeutic cloning has garnered a great deal of attention over the past few years, but until now it had only been achieved in the mouse. (nih.gov)
Their report, published in the same issue of the journal, confirms that therapeutic cloning has now been accomplished in primates for the first time. (nih.gov)
Although this study proves that the therapeutic cloning of primates is possible, there are still many hurdles to be overcome. (nih.gov)
Given that we have an efficiency of 1% cloning for livestock species and if only one in a thousand cells are viable then around 100,000 cells would need to be transferred. (wikiquote.org)
And he also agrees that if we don't find global agreement on human cloning, "we can probably expect dire consequences for the future of biomedical research and its impact on society at large. (lifeissues.net)
But he is equally concerned about the unethical aspects inherent in the rush to perform " therapeutic " human cloning research, including the abuses to all vulnerable human patients who would be required to participate in clinical trials. (lifeissues.net)
Ramsey's statement could thus not apply to the issue of human cloning to begin with. (lifeissues.net)
b) But there is a more fundamental reason why Ramsey's statement might not apply to the issue of human cloning. (lifeissues.net)
a) It would seem that Saunders uses the "potential" argument here quite appropriately, but it is critical that the term be understood properly in order to deflect any misunderstandings or misinterpretations - especially if the term were to be used in any U. N. treaty on human cloning. (lifeissues.net)
If the term "potential" were to be incorporated into a U. N. treaty on human cloning, it would be necessary to clarify its use as referring to an already existing human being/person. (lifeissues.net)
Gurdon's results surprised the scientific community and stirred talk of the possibility of cloning other animals, including humans. (ed.ac.uk)
However, therapeutic cloning depends on the availability of human eggs, which are in very limited supply. (ed.ac.uk)
Human cloning involves creating embryos with the intent of implanting them in women to produce children. (boloji.com)
In therapeutic cloning on the other hand, genetic material from a body cell is inserted into an egg cell, replacing the nucleus. (boloji.com)
Last year, the Republican-controlled House of Representatives in the US Congress passed a bill banning all human cloning, a measure President Bush supports. (boloji.com)
The Society for Women's Health Research, a non-profit group, agrees that therapeutic cloning should be allowed. (boloji.com)
While supporting a ban on the cloning of a human being, the Society believes that the ban should not deter important advancements in scientific technology. (boloji.com)
In June 2002, numerous international organizations joined the Collective in issuing a statement on human cloning in which they called on Congress to pass a strong, effective ban on using human cloning to create a human being. (boloji.com)
There is no way that human cloning could be developed without unethical mass experimentation on women and children,' they said. (boloji.com)
At the same time, the statement calls for a five-year moratorium on the use of cloning to create human embryos for research purposes. (boloji.com)
from nationalreview.com Let's call it "stealth human-cloning legalization. (cbc-network.org)
It's easy to do: First, write a proposed law that you claim outlaws human cloning. (cbc-network.org)
your supposed cloning ban actually authorizes human cloning, implantation, and gestation through the ninth month. (cbc-network.org)
That is what New Jersey legislators did when they passed and then Governor James McGreevey signed S-1909 last year, a law that was sold to the public as outlawing human cloning but which actually permits the creation of cloned human life, and its implantation and gestation up to and including the very moment prior to the emergence of the cloned baby from the birth canal. (cbc-network.org)
The second way to reproduce is a strictly human invention - known as "asexual" reproduction - or more commonly, cloning. (cbc-network.org)
At that point - and this is important to understand - there is no more cloning to be done since a new human organism now exists. (cbc-network.org)
If the cloned human organism is to be experimented upon and destroyed, the process is often called "therapeutic cloning. (cbc-network.org)
They are different uses for the cloned human lives created via cloning. (cbc-network.org)
If the authors of this bill really meant what they appear to have written, their legislation would ban all human cloning, since as we have seen, biologically, a new human organism, that is, a new human being, comes into existence with the completion of SCNT. (cbc-network.org)
It defines the term "cloning of a human being" inaccurately. (cbc-network.org)
Or to put it the other way around, cloning, not implantation, is what produces a new and distinct human organism. (cbc-network.org)
Unfortunately these researchers will be working with one hand tied behind their back because these countries and California are working with restrictive legislation that forbids or impedes the cloning of human embryos. (sicklecellpalmbeach.org)
With only one company in the Grand Unites States openly working on therapeutic cloning, the U.S.A is left in the dust where innovative research and future cures are concerned.The U.S. was once at the forefront of medicine and technology, research and innovation, cures and prevention. (sicklecellpalmbeach.org)
Over the past few years, the debate over stem cells and cloning has grown both more complex and more profound. (eppc.org)
Therapeutic cloning possesses enormous potential for revolutionizing medical and thera- peutic techniques. (who.int)
This is therapeutic cloning. (who.int)
So long as this form of cloning (non-human) in different culture media. (who.int)
However, it appears that the ability of the In its simplest form, cloning is defined stem cells to transform is limited, except as the exact replication of cells. (who.int)
This cell then has therapeutic cloning: the global the capacity to divide and grow into an exact replica of the original from whom the debate somatic cell was taken. (who.int)

Commercial egg lecithin, specified in the United States National Formulatory (USP/NF) as used by pharmaceutical companies, is a highly purified mixture of phospholipids, devoid of triglycerides, cholesterol, or proteins. (wikipedia.org)
Egg-derived lecithin is not usually a concern for those allergic to eggs since commercially available food grade egg lecithin is devoid of allergy causing egg proteins. (wikipedia.org)
The other benefits of chickens are that they can make proteins that behave more like human proteins compared to some cells and some other mammals. (thenakedscientists.com)
And so, when you give these proteins to humans as a therapeutic, they are less likely to cause an immune response - a negative immune response and they're also more likely to be active compared to proteins made in other systems. (thenakedscientists.com)

So it is unlikely that the cells would be viable. (wikiquote.org)
Let's say that one in a thousand cells were nevertheless viable, practical issues come into play. (wikiquote.org)

At the top of the list comes the zygote-a fertilized egg, which of course has the ability to divide and differentiate into all cell types in the body and create a new organism. (thefutureofthings.com)
The first three divisions of the zygote give birth to eight totipotent cells, each of which also has the ability to become an entire organism. (thefutureofthings.com)
if the different cells emerged from the same zygote, it is called a mosaicism . (zubiaga.org)

A number of large biotech companies and scientists are looking toward stem cells as the basis for a therapeutic solution to cure such illnesses as blindness, diabetes and spinal cord injuries. (thefutureofthings.com)
Treatment at the Newcastle NHS Fertility Centre, which will offer the scheme, usually costs £3,500, if a woman agrees to surrender half of her derived eggs to scientists the fee will be halved. (progress.org.uk)
The eggs will then be used by scientists from Newcastle and Durham Universities to create embryos from which they will attempt to derive stem cells . (progress.org.uk)
Until now scientists have been restricted to using 'left-over' eggs from IVF treatment, these are usually poor quality and are already older than those that will be donated through the new scheme. (progress.org.uk)
Discussing the planned public consultation Angela McNab, chief executive of the HFEA, said, 'We know there are a wide variety of views on the subject of donating eggs for research and we anticipate a strong response to the consultation from professional groups, scientists, clinicians and patients as well as the public. (progress.org.uk)
As the cell begins to divide, scientists believe stem cells can be extracted and grown into tissue or organs. (boloji.com)
Long before the controversy emerged over human embryonic stem cells, scientists and doctors began using first-generation stem cells from adult bone marrow. (eppc.org)
But they are also less equipped to produce every cell type of the body and less able to reproduce themselves indefinitely, which makes them less appealing to scientists interested in basic research. (eppc.org)
In July 2005, for example, scientists announced that they had engineered adult mouse stem cells into usable mouse eggs, a technique that might one day allow for the creation of human eggs from ordinary human cells. (eppc.org)

In the United States those voluntary donors receive several thousand dollars for each harvest of eggs, and it is hard-earned pay. (discovermagazine.com)

For the first time researchers can now compare iPSC differentiation to the same process an egg goes through after the transfer of a somatic cell genome. (the-scientist.com)
This could help researchers identify abnormalities in iPSC differentiation, correct them, and develop pluripotent stem cells that don't harbor tumorigenic qualities and do not require the use of human embryos. (the-scientist.com)
This general definition includes a wide variety of cells with varying degrees of differentiation potential. (thefutureofthings.com)
The pheromone signalling pathway of baker's yeast belongs to a class of MAPK (mitogen-activated protein kinase) signalling pathways, which in eukaryotes commonly play a key role in the transmission and translation of extracellular stimuli into intracellular responses such as cell differentiation, proliferation or stress responses. (mpg.de)

Their work was supported by NIH's National Institute of Neurological Disorders and Stroke (NINDS), National Institute of Child Health and Human Development (NICHD) and National Center for Research Resources (NCRR). (nih.gov)
As he has questioned the HFEA before, would not the use of vulnerable human patients in clinical trials be premature, dangerous, and unethical given the already acquired knowledge in the research community that such supposed "patient-specific" stem cells would most probably cause serious immune rejection reactions in these patients? (lifeissues.net)
I knew and had great respect for the famous Protestant theologian and bioethicist Paul Ramsey, and used much of his work concerning the use of human subjects in research in my own. (lifeissues.net)
ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary, Lifeline Cell Technology, and has developed cell based skin care products through its subsidiary, Lifeline Skin Care. (intlstemcell.com)
This is the first time the system has been approved in order to derive eggs for research. (progress.org.uk)
There are some risks involved in removing eggs, whether used in IVF or for research purposes, including ovarian hyper-stimulation syndrome. (progress.org.uk)
Dr Calum MacKellar, director of research at the SCHB, added, 'This kind of agreement by women to donate their eggs for research will generally exploit the poorest members of our society. (progress.org.uk)
However, this license surprises me as it is inconsistent with the stance of not paying for eggs for research. (progress.org.uk)
While supporting research that would help to determine whether stem cells have therapeutic effects, they point out that those adult stem cells, umbilical cord stem cells, and embryonic stem cells not derived from embryos created for research can be used. (boloji.com)
``The patient-matching stem cells no longer exist,'' Roe Jung Hye, dean of research of affairs at the university, said in an e-mailed statement. (blogspot.com)
The university has been conducting a probe on Hwang and his research since Dec. 16, including genetic tests on stem cells being stored at the laboratories. (blogspot.com)
The number one lab in the world offering excellence in medical research is Gen Cells Cures owned by Gerald Armstrong. (sicklecellpalmbeach.org)

In addition to their ability to supply cells at the turnover rate of their respective tissues, they can be stimulated to repair injured tissue caused by liver damage, skin abrasions and blood loss. (thefutureofthings.com)
The ability of our body to regenerate some of its tissues is largely owed to the reserves of adult stem cells. (thefutureofthings.com)
Dec. 29, 2005 -- South Korean laboratories used by scientist Hwang Woo Suk no longer have any stem cells created from patients' tissues, the result of the researcher's landmark May 2005 paper, the Seoul National University said. (blogspot.com)
Today, we can derive stem cells from a range of adult and newborn tissues: liver cells, kidney cells, brain cells, fat cells, and umbilical cord blood. (eppc.org)
Each population of cells keeps its own character and the resulting animal is a mixture of tissues. (zubiaga.org)
The stem cells suits human needs, does not cause harm and can be obtained from both adult and fetal does not conflict with religious beliefs, it has tissues, umbilical cord and early embryos. (who.int)

Precise signaling is crucial for the fitness of every living organism: whether during development or while communicating with a possible mating partner, only accurate transmission of received signals enables cells to trigger appropriate responses. (mpg.de)
This observation led to the belief that the DNA in specialised cells was 'fixed' and could not be used to produce a new organism. (ed.ac.uk)

To assist with these experiments, he used ultraviolet light to destroy the egg cell's original DNA and to make the egg cell's membrane easier to penetrate. (ed.ac.uk)

The team had similar results when they used ovarian tumour samples taken directly from patients, showing that their chicken egg model provides a convenient system for replicating human cancer. (medindia.net)
The nanoparticles were loaded with the anti-cancer drug doxorubicin and were tested on human ovarian tumour established in the chicken egg. (medindia.net)
No one knew whether human ovarian tissue could survive the process--after all, that kind of deep freeze normally kills mature eggs. (discovermagazine.com)

Before the technique will ever make it to the clinic, however, researchers must find a way to remove genomic material from the egg cell. (the-scientist.com)

Recent discoveries reveal new error-causing pathways and present a framework for therapeutic strategies to extend the span of female fertility. (mbexc.de)

There are now two ways to create new mammalian life, including humans. (cbc-network.org)

It is quite possible that the advances in human biology in the remainder of the twentieth century will be remembered as the most significant scientific achievement of the animal species known as Homo sapiens . (lifeissues.net)

The most common application of adult stem cells is probably the restoration of blood cells for patients with leukemia, and there are many more applications currently in practice. (thefutureofthings.com)
All patients involved in egg sharing need IVF treatment to help them have a baby. (progress.org.uk)
So, once you got insulin successfully used in human patients, we started thinking, "What else could we make for patients? (thenakedscientists.com)
Infertile patients cannot afford to wait for treatment while their eggs get older. (infertile.com)

Conversely our clinical results with new therapeutic approaches are adding to our understanding of the basic science of reproduction. (infertile.com)

She worries that the demand for women's eggs could create 'an unseemly market' in which low-income women would harvest and sell their eggs for financial gain. (boloji.com)

We may soon be able to grow unlimited numbers of perfectly healthy, fertilizable human eggs in the laboratory. (discovermagazine.com)

In 2006, Shinya Yamanaka and Kazutoshi Takahashi successfully reprogrammed specialised cells into induced pluripotent (iPS) cells. (ed.ac.uk)

The process ends with major surgery, complete with general anesthesia, as a surgeon pierces a donor's vaginal wall with a needle and sucks the eggs out of the ovaries. (discovermagazine.com)
As part of his vision of a dystopian future, Huxley took readers on a tour of a human hatchery where eggs matured in carefully maintained ovaries before being fertilized and developed in bottles. (discovermagazine.com)

The experiment by Robert Briggs and Thomas King suggested that the development of specialised cells was a one-way process that begins in the early stages of an embryo's development. (ed.ac.uk)

As the embryonic cells divide and the daughter cells differentiate, they become increasingly specific. (thefutureofthings.com)

The findings validate this controversial method, and may one day allow therapeutic stem cells to be created from a patient's own genetic material. (the-scientist.com)

Anatomy20

Organisms17

Diseases3

Chemicals and Drugs11

Analytical, Diagnostic and Therapeutic Techniques and Equipment3

Psychiatry and Psychology1

Phenomena and Processes15

Technology, Industry, Agriculture5

Information Science1

Embryo33

Reproductive13

Transplantation6

Stem cell38

Sperm7

Monoclonal antibodies1

Reprogram4

Fertilisation and Embryology Authority1

Nucleus has been removed2

Oocytes3

Ethical9

Pluripotent human1

Somatic transfer1

Clone7

Therapies4

Chromosomes3

Organisms3

Nuclear8

Embryonic development1

Donor4

Diseases4

Genetically modified3

Oocyte2

Tumors2

Beings1

Germ cells1

Fertilization6

Progenitor1

Genes2

Cloning40

Proteins4

Viable2

Zygote3

Scientists9

Donors1

Differentiation4

Research12

Tissues6

Organism2

Cell's1

Ovarian3

Researchers1

Fertility1

Mammalian1

Biology1

Patients4

Approaches1

Women's1

Laboratory1

Successfully1

Ovaries2

Development1

Divide1

Genetic material1