Efficacy proteasome inhibitors. Medical search. Frequent questions

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Anatomy20

Cell Line, Tumor Cell Line Tumor Cells, Cultured Cells, Cultured Endoplasmic Reticulum HeLa Cells Cell Nucleus COS Cells HEK293 Cells Fibroblasts Cytosol Jurkat Cells Mitochondria K562 Cells HCT116 Cells Inclusion Bodies Cell Line, Transformed HL-60 Cells Cytoplasm Lysosomes

Organisms9

Mice, Nude Thermoplasma Mice, Inbred C57BL Saccharomyces cerevisiae Rats, Sprague-Dawley Mice, Inbred BALB C Mice, SCID Cercopithecus aethiops Cricetinae

Diseases6

Multiple Myeloma Neoplasms Disease Models, Animal Lymphoma, Mantle-Cell Hyalinosis, Systemic Prostatic Neoplasms

Chemicals and Drugs106

Proteasome Inhibitors Proteasome Endopeptidase Complex Leupeptins Boronic Acids Pyrazines Cysteine Proteinase Inhibitors Cysteine Endopeptidases Multienzyme Complexes Protease Inhibitors Acetylcysteine Ubiquitins Ubiquitin Oligopeptides Antineoplastic Agents Lactones Ubiquitinated Proteins NF-kappa B Peptide Hydrolases Polyubiquitin Enzyme Inhibitors Ubiquitin-Protein Ligases Chymotrypsin Thiostrepton Caspases I-kappa B Proteins Protein Subunits Proto-Oncogene Proteins c-bcl-2 RNA, Small Interfering RNA, Messenger Pyrroles Clioquinol Myeloid Cell Leukemia Sequence 1 Protein Ubiquitin-Conjugating Enzymes Ubiquitin-Activating Enzymes Caspase 3 Calpain Protein Synthesis Inhibitors Proteins Dipeptides Butanes Tumor Suppressor Protein p53 Endopeptidases DNA-Binding Proteins Cyclin-Dependent Kinase Inhibitor p27 Apoptosis Regulatory Proteins Lactams, Macrocyclic Cell Cycle Proteins Benzoquinones TNF-Related Apoptosis-Inducing Ligand Neoplasm Proteins HSP90 Heat-Shock Proteins Recombinant Proteins Molecular Chaperones Transcription Factors Adenosine Triphosphatases Carrier Proteins Membrane Proteins Histone Deacetylase Inhibitors Nuclear Proteins Thiocarbamates bcl-2-Associated X Protein Sulfones HSP70 Heat-Shock Proteins Caspase Inhibitors Hydroxamic Acids Activating Transcription Factor 4 Recombinant Fusion Proteins Reactive Oxygen Species Cyclin-Dependent Kinase Inhibitor p21 Cycloheximide Tumor Necrosis Factor-alpha Glutathione Synthase Intracellular Signaling Peptides and Proteins HSP72 Heat-Shock Proteins Hydroxyquinolines Transcription Factor CHOP Peptides Proto-Oncogene Proteins c-mdm2 Ligases Chloroquine Microtubule-Associated Proteins Antibiotics, Antineoplastic Proto-Oncogene Proteins Protein-Serine-Threonine Kinases Amino Acid Chloromethyl Ketones Caspase 8 Tumor Suppressor Proteins Boron Compounds 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt Heat-Shock Proteins Peptide Fragments Saccharomyces cerevisiae Proteins Ubiquitin-Protein Ligase Complexes Phthalimides X-Linked Inhibitor of Apoptosis Protein Green Fluorescent Proteins SKP Cullin F-Box Protein Ligases Receptors, TNF-Related Apoptosis-Inducing Ligand Triterpenes S-Phase Kinase-Associated Proteins Muscle Proteins DNA Primers Semicarbazones Cullin Proteins Peptides, Cyclic bcl-2 Homologous Antagonist-Killer Protein

Analytical, Diagnostic and Therapeutic Techniques and Equipment19

Blotting, Western Treatment Outcome Transfection Xenograft Model Antitumor Assays Immunoblotting Drug Screening Assays, Antitumor Models, Biological Reverse Transcriptase Polymerase Chain Reaction Immunoprecipitation Inhibitory Concentration 50 Disease Models, Animal Antineoplastic Combined Chemotherapy Protocols Drug Evaluation, Preclinical Clinical Trials as Topic Flow Cytometry Drug Administration Schedule Drug Therapy, Combination Double-Blind Method Microscopy, Fluorescence

Phenomena and Processes42

Apoptosis Ubiquitination Proteolysis Drug Synergism Down-Regulation Dose-Response Relationship, Drug Drug Resistance, Neoplasm Protein Processing, Post-Translational Signal Transduction Cell Survival Time Factors Transfection Protein Binding Enzyme Activation Phosphorylation Amino Acid Sequence Mutation Cell Death Cell Proliferation Cell Cycle Protein Transport Protein Stability Autophagy Hydrolysis Up-Regulation Gene Expression Regulation Unfolded Protein Response RNA Interference Inhibitory Concentration 50 Protein Structure, Tertiary Transcription, Genetic Oxidative Stress Endoplasmic Reticulum-Associated Degradation Endoplasmic Reticulum Stress Protein Folding Protein Biosynthesis Substrate Specificity Cell Division Gene Expression Regulation, Neoplastic Gene Expression Kinetics Antigen Presentation

Information Science2

Molecular Sequence Data Amino Acid Sequence

Health Care3

Treatment Outcome Clinical Trials as Topic Double-Blind Method

Anatomy Organisms Diseases Chemicals and Drugs Analytical, Diagnostic and Therapeutic Techniques and Equipment Phenomena and Processes Information Science Health Care

Proteasome Inhibitors Proteasome Endopeptidase Complex Leupeptins Boronic Acids Pyrazines Cysteine Proteinase Inhibitors Cysteine Endopeptidases Multienzyme Complexes Protease Inhibitors Acetylcysteine Ubiquitins Ubiquitin Apoptosis Oligopeptides Antineoplastic Agents Cell Line, Tumor Ubiquitination Lactones Multiple Myeloma Proteolysis Cell Line Ubiquitinated Proteins NF-kappa B Drug Synergism Peptide Hydrolases Polyubiquitin Blotting, Western Enzyme Inhibitors Ubiquitin-Protein Ligases Down-Regulation Dose-Response Relationship, Drug Chymotrypsin Tumor Cells, Cultured Thiostrepton Drug Resistance, Neoplasm Caspases Protein Processing, Post-Translational I-kappa B Proteins Treatment Outcome Signal Transduction Cell Survival Cells, Cultured Endoplasmic Reticulum Protein Subunits Time Factors HeLa Cells Transfection Proto-Oncogene Proteins c-bcl-2 Xenograft Model Antitumor Assays Protein Binding RNA, Small Interfering Enzyme Activation Molecular Sequence Data Phosphorylation Immunoblotting RNA, Messenger Amino Acid Sequence Mutation Pyrroles Clioquinol Cell Death Cell Proliferation Cell Cycle Myeloid Cell Leukemia Sequence 1 Protein Ubiquitin-Conjugating Enzymes Ubiquitin-Activating Enzymes Caspase 3 Calpain Protein Transport Protein Synthesis Inhibitors Proteins Protein Stability Neoplasms Dipeptides Drug Screening Assays, Antitumor Autophagy Butanes Tumor Suppressor Protein p53 Endopeptidases DNA-Binding Proteins Cyclin-Dependent Kinase Inhibitor p27 Apoptosis Regulatory Proteins Models, Biological Lactams, Macrocyclic Cell Cycle Proteins Cell Nucleus COS Cells Reverse Transcriptase Polymerase Chain Reaction HEK293 Cells Benzoquinones Hydrolysis Up-Regulation Gene Expression Regulation TNF-Related Apoptosis-Inducing Ligand Unfolded Protein Response RNA Interference Neoplasm Proteins Immunoprecipitation HSP90 Heat-Shock Proteins Mice, Nude

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