CefuroximeCiprofloxacinPenicillinAntibioticsChloramphenicolTerms of safety and efficacyParenteralCephalosporinCephalosporinsMeropenemVial containsAmoxicillinAntibioticRocephinClaforanAntimicrobialLevofloxacinMeningitisDoxycyclinePneumoniaeStrainsClinical efficacyMECHANISM OF ACTSafetyPreventionCefoxitinInfectionBacterialEnterococcusDosesResistanceFeverDifferPatientsRiskData
Cefuroxime1
- In meningitis, cefotaxime crosses the blood-brain barrier better than cefuroxime. (wikipedia.org)
Ciprofloxacin3
- Evaluation of the efficacy and safety of intravenous ciprofloxacin versus meropenem in the treatment of postoperative infection. (druglib.com)
- In vivo efficacy of the combination of ciprofloxacin and cefotaxime against Vibrio vulnificus sepsis. (tactical-medicine.com)
- She was treated with ceftriaxone and ciprofloxacin. (biomedcentral.com)
Penicillin5
- citation needed] As a β-lactam antibiotic in the third-generation class of cephalosporins, cefotaxime is active against numerous Gram-positive and Gram-negative bacteria, including several with resistance to classic β-lactams such as penicillin. (wikipedia.org)
- For injectable drugs , cefotaxime and ceftriaxone were more effective than penicillin. (lymetalk.net)
- [14] Treatment when infected is with antibiotics such as doxycycline, penicillin , or ceftriaxone . (mdwiki.org)
- Vancomycin : It is a glycopeptide antibiotic discovered in 1956 as a penicillin substitute which has assumed special significance due to efficacy against MRSA, Strep. (pharmacy180.com)
- 7 In tropical countries, there has been an emergence of Streptococcus pneumoniae that is resistant to penicillin, cefotaxime, and chloramphenicol. (jabfm.org)
Antibiotics2
- Contraindicated in patients with known hypersensitivity to ceftriaxone or to the cephalosporin class of antibiotics. (torquepharma.com)
- Cefotaxime injection is in a class of medications called cephalosporin antibiotics. (onteenstoday.com)
Chloramphenicol15
- In a study, conducted by Department of Paediatrics and Child Health and Faculty of Medicine of the University of Natal (situated in Durban, Republic of South Africa) compared the efficacy of chloramphenicol and ceftriaxone for the treatment of typhoid fever. (medicotips.com)
- All children were culture positive for Salmonella typhi(causative agent of typhoid fever) and bacterial strains are equally sensitive to both ceftriaxone and chloramphenicol. (medicotips.com)
- The ceftriaxone group contained 29 patients and the chloramphenicol group contained 30 patients. (medicotips.com)
- Ceftriaxone was given intramuscularly in a dose of 80mg/kg/day for five days and chloramphenicol was given via oral route in a daily dose of 50-100 mg/kg/day in three divided doses for three weeks (21 days). (medicotips.com)
- This study concluded that ceftriaxone is a better alternative to treat typhoid fever as compared to conventional chloramphenicol. (medicotips.com)
- Because only 5 days of ceftriaxone therapy gives us the same results as those of 21 days long chloramphenicol therapy. (medicotips.com)
- In another study (Treatment of typhoid fever with ceftriaxone for 5 days or chloramphenicol for 14 days, a randomized clinical trial by Aslam, T butler, I Kabir), All patients treated with ceftriaxone became culture negative on third day of treatment while 60 % of those patients who were treated with chloramphenicol were still culture positive. (medicotips.com)
- This study also concluded that 5 days of ceftriaxone therapy is a better alternative to 14 days long chloramphenicol therapy for the treatment of typhoid fever. (medicotips.com)
- Another latest study (2013) that is conducted in Abbassia Fever Hospital, Egypt also declared 5 days treatment course of ceftriaxone as a better alternative to 14-21 days long course of chloramphenicol therapy. (medicotips.com)
- The duration of ceftriaxone therapy is significantly lesser than chloramphenicol therapy. (medicotips.com)
- The patients become culture negative earlier with ceftriaxone as compared to chloramphenicol. (medicotips.com)
- Moreover, resistant strains to chloramphenicol have emerged but resistant strains to ceftriaxone are not yet reported (2013). (medicotips.com)
- Ceftriaxone versus Chloramphenicol for Treatment of Acute Typhoid Fever Osama Mohamed Hammad et all. (medicotips.com)
- Treatment of typhoid fever with ceftriaxone for 5 days or chloramphenicol for 14 days: a randomized clinical trial. (medicotips.com)
- Once daily ceftriaxone vs. chloramphenicol for treatment of typhoid fever in children.Moosa A, Rubidge CJ. (medicotips.com)
Terms of safety and efficacy1
- In most cases, it is equivalent to ceftriaxone in terms of safety and efficacy. (loinc.org)
Parenteral2
- Cefotaxime sodium, a parenteral cephalosporin antibiotic, exerts its bactericidal action through inhibition of bacterial cell wall synthesis. (onteenstoday.com)
- Alternative regimens include cefoxitin 2 g IM in a single dose and probenecid 1 g orally administered concurrently in a single dose with doxycycline 100 mg orally twice a day and metronidazole 500 mg orally twice a day for 14 days or other parenteral third-generation cephalosporin (e.g., ceftizoxime or cefotaxime) with doxycycline 100 mg orally twice a day and metronidazole 500 mg orally twice a day for 14 days. (reliasmedia.com)
Cephalosporin4
- Cefotaxime is a third-generation cephalosporin antibiotic. (loinc.org)
- Cefotaxime is a third generation cephalosporin, with activity similar to ceftizoxime and cefotaxime. (loinc.org)
- Ceftriaxone is a cephalosporin (SEF a low spor in) antibiotic. (onteenstoday.com)
- For saltwater injuries secondary to stingrays, it is important to cover for vibrio vulnificus with a third-generation cephalosporin and a tetracycline (e.g., ceftriaxone and doxycycline) or a fluoroquinolone. (tactical-medicine.com)
Cephalosporins3
- citation needed] Cefotaxime is contraindicated in patients with a known hypersensitivity to cefotaxime or other cephalosporins. (wikipedia.org)
- This finding is of clinical importance prevalence in sickle cell disease patients may decrease the efficacy of third-generation cephalosporins in invasive since it precludes using cephalosporins as a treatment pneumococcal disease. (cdc.gov)
- This implicates ceftriaxone in causing the highest rate of fatality amongst cephalosporins and drugs in general. (rhochistj.org)
Meropenem3
- Efficacy of ceftriaxone or meropenem as initial therapies in Whipple's disease. (druglib.com)
- The efficacy and safety of meropenem and tobramycin vs ceftazidime and tobramycin in the treatment of acute pulmonary exacerbations in patients with cystic fibrosis. (druglib.com)
- Efficacy of meropenem as monotherapy in the treatment of ventilator-associated pneumonia. (druglib.com)
Vial contains1
- Each vial contains ceftriaxone sodium equivalent to 250 mg, 500 mg, 1 gram or 2 grams of ceftriaxone activity. (onteenstoday.com)
Amoxicillin2
- Is ceftriaxone the same as amoxicillin? (onteenstoday.com)
- We conclude the following: (1) Cefixime and amoxicillin were equivalent in overall clinical and bacteriologic efficacy for otitis media. (onteenstoday.com)
Antibiotic5
- Cefotaxime is an antibiotic used to treat a number of bacterial infections in human, other animals and plant tissue culture. (wikipedia.org)
- citation needed] The most common adverse reactions experienced are: Pain and inflammation at the site of injection/infusion (4.3%) Rash, pruritus, or fever (2.4%) Colitis, diarrhea, nausea, vomiting (1.4%) Cefotaxime is a β-lactam antibiotic (which refers to the structural components of the drug molecule itself). (wikipedia.org)
- What type of antibiotic is cefotaxime? (onteenstoday.com)
- Is cefotaxime an antibiotic? (onteenstoday.com)
- Cefotaxime is a broad-spectrum antibiotic that is FDA-approved and indicated to treat gram-positive, gram-negative, and anaerobic organisms of susceptible strains causing pneumonia, urinary tract infections, cervicitis, endometritis, urethritis, and sepsis. (onteenstoday.com)
Rocephin1
- A brand name for ceftriaxone is Rocephin. (onteenstoday.com)
Claforan1
- Cefotaxime sodium is marketed under various trade names including Claforan (Sanofi-Aventis). (loinc.org)
Antimicrobial2
- Since Nocardia species infections are very often sporadic, information from randomized clinical trials comparing the clinical efficacy of specific antimicrobial agents is lacking. (antimicrobe.org)
- We were unable to track patients through follow-up urine specimen testing to determine efficacy of antimicrobial treatment. (bmj.com)
Levofloxacin1
- He was discharged on oral levofloxacin after treatment in ED with intravenous ceftriaxone and doxycycline. (tactical-medicine.com)
Meningitis4
- CNS infections - e.g. meningitis/ventriculitis secondary to N. meningitidis, H. influenzae, S. pneumoniae Although cefotaxime has demonstrated efficacy in these infections, it is not necessarily considered to be the first-line agent. (wikipedia.org)
- Ceftriaxone is used to treat many kinds of bacterial infections, including severe or life-threatening forms such as E. coli, pneumonia, or meningitis. (onteenstoday.com)
- Ceftriaxone is also used to treat pelvic inflammatory disease, bacterial septicemia, bone and joint infections, and meningitis. (onteenstoday.com)
- For empirical therapy of bacterial meningitis, i.v. vancomycin is usually combined with i.v. ceftriaxone/cefotaxime. (pharmacy180.com)
Doxycycline2
- Additionally, for outpatient PID therapy, cefotaxime may be administered with oral doxycycline with or without oral metronidazole for 14 days. (onteenstoday.com)
- The recommended outpatient IM/oral treatment regimens for PID now are ceftriaxone 500 mg IM in a single dose with doxycycline 100 mg orally twice a day and metronidazole 500 mg orally twice a day for 14 days. (reliasmedia.com)
Pneumoniae2
- citation needed] Given its broad spectrum of activity, cefotaxime is used for a variety of infections, including: Lower respiratory tract infections - e.g. pneumonia (most commonly caused by S. pneumoniae) Genitourinary system infections - urinary tract infections (e.g. (wikipedia.org)
- While regional susceptibilities must always be considered, cefotaxime typically is effective against these organisms (in addition to many others): Staphylococcus aureus (not including MRSA) and S. epidermidis Streptococcus pneumoniae and S. pyogenes Escherichia coli Haemophilus influenzae Neisseria gonorrhoeae and N. meningitidis Klebsiella spp. (wikipedia.org)
Strains1
- These first time in 3 clones: Maryland6B, ST660, and a novel strains displayed MICs of cefotaxime and ceftriaxone from clone, ST1753. (cdc.gov)
Clinical efficacy1
- 4 Clinical and PK/PD data demonstrate colistin has limited clinical efficacy, even if an intermediate result is obtained. (cdc.gov)
MECHANISM OF ACT1
- What is the mechanism of action of cefotaxime? (onteenstoday.com)
Safety3
- EXD-12 is a vaccine candidate currently in preclinical testing for safety and efficacy as a prophylactic and therapeutic vaccine for both Herpes Simplex Virus-1, HSV-1, and Herpes Simplex Virus-2, HSV-2. (precisionvaccinations.com)
- GSK's Simplirix HerpeVac was in a double-blind, randomized, controlled phase 3 clinical study to assess the prophylactic efficacy and safety of gD-Alum/MPL vaccine in preventing genital herpes disease in young women who are herpes simplex virus (HSV)-1 and -2 seronegative. (precisionvaccinations.com)
- Manufacturers have sought approval and provided evidence as to the safety and efficacy of their products only when used in accordance with the product monographs or other similarly approved standards or instructions for use. (canada.ca)
Prevention1
- Current data regarding the efficacy of prevention strategies and management approaches form the basis for the guidelines. (cdc.gov)
Cefoxitin1
- Of the 53 patients, 43 were due to cefotetan, eight due to ceftriaxone, one due to cefotaxime, and one due to cefoxitin. (rhochistj.org)
Infection1
- Ceftriaxone is also used to prevent infection in people having certain types of surgery. (onteenstoday.com)
Bacterial2
- Ceftriaxone works by inhibiting the mucopeptide synthesis in the bacterial cell wall. (onteenstoday.com)
- The beta-lactam moiety of ceftriaxone binds to carboxypeptidases, endopeptidases, and transpeptidases in the bacterial cytoplasmic membrane. (onteenstoday.com)
Enterococcus1
- Notable organisms against which cefotaxime is not active include Pseudomonas and Enterococcus. (wikipedia.org)
Doses1
- However, ceftriaxone has the advantage of once-daily dosing, whereas the shorter half-life of cefotaxime necessitates two or three daily doses for efficacy. (wikipedia.org)
Resistance2
- Changing patterns in microbial resistance suggest cefotaxime may be suffering greater resistance than ceftriaxone, whereas the two were previously considered comparable. (wikipedia.org)
- Le pneumocoque de sensibilite diminuee a la penicilline G (PSDP) representait 53;3des souches (n=225) et 12;8avaient une resistance de haut niveau.29;6avaient une sensibilite diminuee a l'amoxicilline et 15;1au cefotaxime. (bvsalud.org)
Fever1
- Fever persisted in some patients treated with ceftriaxone for prolong period of time. (medicotips.com)
Differ1
- The clinical and laboratory findings in ceftriaxone DIIHA differ dramatically from other associated drugs, such as cefotetan. (rhochistj.org)
Patients4
- In the ceftriaxone group twenty-three patients became culture negative and free of disease, 2 improved significantly, one failed to improve and two patients relapsed. (medicotips.com)
- Table 1 shows that among the patients with ceftriaxone-induced hemolytic anemia, five were tested, and none had antibodies for IgA & IgM. (rhochistj.org)
- 8 Of the eight ceftriaxone induced hemolytic anemia patients tested for IgG antibodies, six were shown to be positive. (rhochistj.org)
- Furthermore, RBC-bound complement was detected in all patients with DIIHA caused by ceftriaxone. (rhochistj.org)
Risk2
- own wirtschaftliche mixtures are intended in back of a 40 risk public water, first if ceftriaxone warns outlined. (stb-mette.eu)
- For some substances there is also a risk assessment made on the basis of concentrations measured in the environment in Sweden and efficacy studies with high quality. (janusinfo.se)
Data1
- data regarding efficacy are conflicting. (drugs.com)